Perfusion imaging by un-inverted flow-sensitive alternating inversion recovery (UNFAIR).

Abstract:

:A new pulse sequence for estimating cerebral blood flow called UNFAIR, which uses a combination of sequential hyperbolic secant preparatory pulses, is introduced. This sequence is based on the same generalized conditions as previously introduced inversion recovery techniques except that the spins in the image slice of interest always have +z magnetization and the in-flowing spins are alternately inverted and uninverted. CBF-weighted images of rat brain under conditions of normocpnia and hypercapnia are presented and demonstrate the expected CBF response. A model describing the signal response to this pulse sequence is also presented and compared with in-vivo data acquired from gray and white matter.

journal_name

Magn Reson Imaging

authors

Helpern JA,Branch CA,Yongbi MN,Huang NC

doi

10.1016/s0730-725x(96)00353-0

subject

Has Abstract

pub_date

1997-01-01 00:00:00

pages

135-9

issue

2

eissn

0730-725X

issn

1873-5894

pii

S0730-725X(96)00353-0

journal_volume

15

pub_type

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