Abstract:
:NMR offers, in the complex proton relaxation properties of biological tissues, a unique and potentially powerful tool of tissue characterization. The difficulties encountered so far in comparing the results of in vitro and in vivo NMR studies carried out in different laboratories inhibit NMR methodologies from fully expressing their content of physiopathological information, as well as their potential for therapeutic monitoring. Moreover, obtaining accurate data on proton relaxation in vivo requires accurate location of the anatomical region under study. The acquisition of acceptable information about location and effects is dependent on the establishment of agreed procedures for tests, as well as on the use of appropriate test objects and test substances. A concerted research project entitled "Identification and Characterization of Biological Tissues by NMR" was activated in 1984 by the European Economic Community as part of the Third Medical Research Program, under the auspices of the Biomedical Engineering Concerted Action Committee. A series of papers is presented here which illustrates objectives and scientific programs of this project, the protocols adopted for multi-center comparison of in vitro and in vivo studies, and the results of validating trials, as well as problems of reference substances.
journal_name
Magn Reson Imagingjournal_title
Magnetic resonance imagingauthors
Podo F,Orr JS,Schmidt KH,Bovée WMdoi
10.1016/0730-725x(88)90447-xsubject
Has Abstractpub_date
1988-03-01 00:00:00pages
175-8issue
2eissn
0730-725Xissn
1873-5894pii
0730-725X(88)90447-Xjournal_volume
6pub_type
杂志文章abstract::1H-nuclear magnetic resonance (NMR) measurements have been carried out on a banded sandstone to investigate the effects of structural inhomogeneities on the fluid dynamics of the sample as a whole. The results obtained from average propagator measurements (the probability of a displacement z in a time delta or P delta...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/s0730-725x(98)00043-5
更新日期:1998-06-01 00:00:00
abstract::With the aim of developing a fast algorithm for high-quality MRI reconstruction from undersampled k-space data, we propose a novel deep neural Network, which is inspired by Iterative Shrinkage Thresholding Algorithm with Data consistency (NISTAD). NISTAD consists of three consecutive blocks: an encoding block, which m...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2020.04.016
更新日期:2020-07-01 00:00:00
abstract:INTRODUCTION:Pharmacokinetic parameters derived from dynamic contrast-enhanced MRI (DCE-MRI) data are sensitive to acquisition and post-processing techniques, which makes it difficult to compare results obtained using different methods. In particular, one of the most important factors affecting estimation of model para...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2018.05.007
更新日期:2018-10-01 00:00:00
abstract::The purpose of this study was to analyze background parenchymal enhancement (BPE) in the contralateral normal breast of cancer patients during the course of neoadjuvant chemotherapy (NAC). Forty-five subjects were analyzed. Each patient had three MRIs, one baseline (B/L) and two follow-up (F/U) studies. The fibrogland...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2013.07.014
更新日期:2013-11-01 00:00:00
abstract::When assessing liver iron content using relaxometry, an average relaxation rate (R1, R2 or R2*) is usually determined from a region of interest or the entire liver. This is commonly performed by fitting the signal decay in individual voxels to an appropriate relaxation function. The voxel-level parameters resulting fr...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2010.11.005
更新日期:2011-05-01 00:00:00
abstract::Multi-echo pulse sequences for producing T2-weighted images in much reduced imaging times have recently been developed for routine clinical use. A number of recent articles have described the contrast obtained with fast spin-echo (FSE) sequences and have generally indicated that they depict tissues very similarly to c...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章,评审
doi:10.1016/0730-725x(92)90001-g
更新日期:1992-01-01 00:00:00
abstract::Metabolic imaging of hyperpolarized [1-(13)C] pyruvate co-polarized with [(13)C]urea by dynamic nuclear polarization with rapid dissolution is a promising new method for assessing tumor metabolism and perfusion simultaneously in vivo. Novel pulse sequences are required to enable dynamic imaging of multiple (13)C spect...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2012.06.037
更新日期:2013-02-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to analyze flow patterns in the pulmonary circulation of healthy volunteers by using 4D flow magnetic resonance imaging. MATERIALS AND METHODS:The study was approved by the local ethics committee and all subjects gave written informed consent. Eighteen volunteers underwent a 4D ...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2012.06.036
更新日期:2013-02-01 00:00:00
abstract::In this contribution, we report results from MRI studies of the propagation of heavy metal ions through columns packed with sandy aquifer materials. Both sorption of low concentrations of heavy metal ions from water flowing through the column and the formation of sorption traces produced from initially localized highe...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/s0730-725x(03)00166-8
更新日期:2003-04-01 00:00:00
abstract::Type A acute aortic dissection (TAAAD) sometimes presents with acute stroke-like symptoms. When intravenous tissue plasminogen activator (IV-tPA) therapy is considered for acute ischemic stroke, TAAAD must be excluded. Painless TAAAD presenting with acute stroke may be easily missed. Two cases of painless TAAAD presen...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2016.04.021
更新日期:2016-09-01 00:00:00
abstract::B(1) Field inhomogeneity and the relative effects of dielectric resonances are analyzed within the context of ultra high field MRI. This is accomplished by calculating the electromagnetic fields inside spherical phantoms and within a human head model in the presence and absence of an RF coil. These calculations are th...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/s0730-725x(01)00300-9
更新日期:2001-02-01 00:00:00
abstract::Tracking of signal intensity changes in soft tissue over time is often hampered by deformation of the tissue. In this study a method is described that uses finite element modeling to compensate for tissue deformation. The method is applied to the quantification of fluid redistribution in an intervertebral disc that de...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/s0730-725x(97)00251-8
更新日期:1998-01-01 00:00:00
abstract:PURPOSE:To compare the diagnostic performance of the noncontrast MRI including DWI to the standard MRI for detecting hepatic malignancies in patients with chronic liver disease. MATERIALS AND METHODS:We included 135 patients with 136 histologically-confirmed hepatocellular carcinomas (HCCs), 12 cholangiocarcinomas, an...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2013.12.021
更新日期:2014-07-01 00:00:00
abstract:OBJECTIVE:In magnetic resonance-guided breast vacuum biopsies, the contrast agent for targeting suspicious lesions can typically be applied only once during an intervention, due to the slow elimination of the gadolinium chelate from the extracellular fluid space. This study evaluated the feasibility of diffusion-weight...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2016.12.006
更新日期:2017-05-01 00:00:00
abstract::The site-dependent variations in trabecular bone morphology were studied in the rat tibia by magnitude and phase difference three-dimensional nuclear magnetic resonance microscopy and image processing, and the implications of ovariectomy were evaluated. Specimens excised from the proximal tibial metaphysis in ovariect...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/s0730-725x(99)00107-1
更新日期:2000-01-01 00:00:00
abstract:PURPOSE:To assess the value of semi-automated segmentation applied to diffusion MRI for predicting the therapeutic response of liver metastasis. METHODS:Conventional diffusion weighted magnetic resonance imaging (MRI) was performed using b-values of 0, 150, 300 and 450s/mm(2) at baseline and days 4, 11 and 39 followin...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2015.08.006
更新日期:2015-12-01 00:00:00
abstract::The ability to evaluate empirical diffusion MRI acquisitions for quality and to correct the resulting imaging metrics allows for improved inference and increased replicability. Previous work has shown promise for estimation of bias and variance of generalized fractional anisotropy (GFA) but comes at the price of compu...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2019.03.021
更新日期:2019-06-01 00:00:00
abstract::Pellets of HeLa from suspension cultured cells in isotonic medium (300 mosmolar) were introduced into a Bruker CXP100 NMR spectrophotometer at 80 mHz within 5 min of the start of centrifugation. T1 and T2 times were measured within a total elapsed time of 20-25 min at 80 mHz and 37 degrees C, and averaged 1430 msec an...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/0730-725x(90)90101-7
更新日期:1990-01-01 00:00:00
abstract::Transverse relaxation rates for Carr-Purcell-Meiboom-Gill (CPMG) sequences increase with inter-echo time in presence of microscopic magnetic field inhomogeneities due to nuclear spin diffusion. For a weak field approximation that includes diffusion effects, the CPMG relaxation rate shift for proton diffusion around ca...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2016.03.016
更新日期:2016-09-01 00:00:00
abstract::The purpose of this study was to test whether an empirical mathematical model (EMM) of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) can distinguish between benign and malignant breast lesions. A modified clinical protocol was used to improve the sampling of contrast medium uptake and washout. T(1)-we...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2006.10.011
更新日期:2007-06-01 00:00:00
abstract::With the recent development of integrated positron emission tomography-magnetic resonance imaging (PET-MRI) scanners, new possibilities for quantitative molecular imaging of cancer are realized. However, the practical advantages and potential clinical benefits of the ability to record PET and MRI data simultaneously m...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章,评审
doi:10.1016/j.mri.2012.06.001
更新日期:2012-11-01 00:00:00
abstract::Magnetic resonance imaging (MRI) has played an important role in the diagnosis and management of cancer since it was first developed, but other modalities also continue to advance and provide complementary information on the status of tumors. In the future, there will be a major continuing role for noninvasive imaging...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章,评审
doi:10.1016/j.mri.2011.02.003
更新日期:2011-06-01 00:00:00
abstract::Functional MR (fMR) imaging techniques based on blood oxygenation level dependent (BOLD) effects were developed and applied to a rat brain tumor model to evaluate the potential utility of the method for characterizing tumor growth and regression following treatment. Rats bearing 9L brain tumors in situ were imaged dur...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/s0730-725x(98)00208-2
更新日期:1999-05-01 00:00:00
abstract::Gels consist of crosslinked polymer network swollen in solvent. The network of flexible long-chain molecules traps the liquid medium they are immersed in. Some gels undergo abrupt volume change, a phase transition process, by swelling-shrinking in response to external stimuli changes in solvent composition, temperatur...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/s0730-725x(02)00639-2
更新日期:2003-02-01 00:00:00
abstract::We propose a deuterium diffusion tracer approach to measure diffusion coefficient in the case of very short NMR relaxation times, too short for NMR pulsed field gradient sequences (T1 or T2 below 1 ms). We also treat the case of porous media containing metallic fibers (such as reinforced concrete) strongly disturbing ...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2018.09.010
更新日期:2019-02-01 00:00:00
abstract::High-resolution, single-slice, high spatial and spectral resolution (HiSS) breast magnetic resonance imaging (MRI) provides improved lesion conspicuity, margin definition and internal definition, as compared to conventional clinical MRI - and thus may provide better lesion characterization and increase breast MRI spec...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2009.05.022
更新日期:2010-01-01 00:00:00
abstract::Image artifacts due to 14 gauge radiotherapy electromagnetic (EM) transponders were assessed on conventional spin echo images, and corrected using metal artifact reduction techniques: high bandwidth, view angle tilting (VAT), and slice encoding for metal artifact correction (SEMAC). Large areas of signal loss and/or p...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2019.02.005
更新日期:2019-06-01 00:00:00
abstract::One of the main problems with rapid magnetic resonance imaging (MRI) techniques is the artifacts that result from off-resonance effects. The proposed off-resonance frequency filtered MRI (OFF-MRI) method focuses on the elimination of off-resonance components from the image of the observed object. To maintain imaging s...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2009.12.027
更新日期:2010-05-01 00:00:00
abstract:PURPOSE:The purposes of this study were to (1) correlate the ultrashort echo time (TE) signal intensity of the pointwise encoding time reduction with radial acquisition (PETRA) sequence with that of the ultrashort echo (UTE) sequence using in vivo meniscal ultrashort TE imaging of the knee with a 3-Tesla (3T) clinical ...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2015.09.003
更新日期:2016-02-01 00:00:00
abstract::The ability to determine coil sensitivities implies that a method optimized in terms of maximized signal-to-noise ratio (SNR) can be applied to the combination of multiple coil images. An optimization of SNR subsequently results in a minimized variance in quantitative velocity measurements using phase-contrast imaging...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2005.06.002
更新日期:2005-09-01 00:00:00