Mesothelin is more useful in pleural effusion than in serum in the diagnosis of pleural mesothelioma.

abstract：AIM:Mitotane is used in adrenal cancer as adjuvant therapy, monotherapy or combined with other cytotoxic agents in advanced disease, but only 30% of patients respond. The aim of this study was to define the structural requirements for drug activity and to develop analogs with improved adrenalytic action. MATERIALS AND...

journal_title：Anticancer research

authors： Schteingart DE,Sinsheimer JE,Benitez RS,Homan DF,Johnson TD,Counsell RE

更新日期：2012-07-01 00:00:00

abstract：:Flunarizine, a calcium-antagonist drug that binds to calmodulin, was found to inhibit the migration of both B16 melanoma cells and M5076 macrophage-like cancer cells. The migration movement, both under agarose and through a polycarbonate filter membrane, was impaired by the drug. In M5076 macrophage-like cells Fc-depe...

journal_title：Anticancer research

authors： Sezzi ML,De Luca G,Materazzi M,Bellelli L

更新日期：1985-05-01 00:00:00

abstract：:The expression of the protooncogene encoded proteins (c-erbB1, c-erb B2, c-myc, c-fos) and the suppressor gene product p53 was analyzed in 81 human squamous cell carcinomas of the lung and correlated with clinical parameters of the patients (patient survival, presence of metastases and tumor stage) and with biological...

journal_title：Anticancer research

authors： Volm M,Efferth T,Mattern J

更新日期：1992-01-01 00:00:00

abstract：AIM:To assess the ability of ultrasound (US)-guided vacuum-assisted breast excision (VAE) to remove Breast Imaging Reporting and Data System (BI-RADS) ≥3 breast lesions in order to analyze US features most frequently associated with complete excision. MATERIALS AND METHODS:A total of 266 BI-RADS ≥3 lesions without mic...

journal_title：Anticancer research

authors： Perretta T,Lamacchia F,Ferrari D,Beninati E,DI Tosto F,DE Stasio V,Meucci R,DI Stefano C,Buonomo OC,Vanni G,Pistolese CA

更新日期：2020-03-01 00:00:00

abstract：AIM:To seek differences between ductal carcinoma in situ (DCIS) according to the menopausal status of patients and to analyze their repercussions on patient care. PATIENTS AND METHODS:A multicenter retrospective study of 384 patients from 3 centers specialized in breast cancer surgery was carried out based on an analy...

journal_title：Anticancer research

authors： Pradier C,Cornuau M,Norca J,Mesbah H,Poree P,Body G,Classe JM,Leveque J

更新日期：2011-05-01 00:00:00

abstract：AIM:To investigate the prognostic significance of cancer antigen 15-3 (CA15-3) in primary breast cancer (BC). PATIENTS AND METHODS:This prospective study included 368 women: 62 patients with benign breast disease (BBD), 159 patients with invasive BC and 88 healthy blood donors (control). The median follow-up was 76 mo...

journal_title：Anticancer research

authors： Nisman B,Maimon O,Allweis T,Kadouri L,Maly B,Hamburger T,Peretz T

更新日期：2013-01-01 00:00:00

abstract：:We report a 64-year-old woman with a 9-cm liver tumor in the left lateral section. The patient had neither hepatitis B or C virus infection, nor cirrhosis. Carbohydrate antigen 19-9 (CA 19-9) level was 1,889 U/ml. We also suspected bulky hilar lymph node metastasis, and a left lateral sectionectomy without lymph node ...

journal_title：Anticancer research

authors： Miyata T,Beppu T,Imamura YU,Hayashi H,Imai K,Chikamoto A,Yamashita YI,Fukubayashi K,Ishiko T,Baba H

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Sunitinib is a tyrosine kinase inhibitor (TKI) targeting tumour angiogenesis in patients with advanced renal cell carcinoma (RCC). Currently no universally agreed model exists correlating the expression of angiogenesis markers with the success of treatment. PATIENTS AND METHODS:We retrospectively analysed a...

journal_title：Anticancer research

authors： Stubbs C,Bardoli AD,Afshar M,Pirrie S,Miscoria M,Wheeley I,Porfiri E

更新日期：2017-01-01 00:00:00

abstract：:50 patients with advanced breast cancer were treated with the combination of Mitoxantrone 10mg/m2 IV day 2, 5-Fluorouracil 400mg/m2 IV and Cyclophosphamide 300mg/m2 IV day 3, 4, 5, 6 of each monthly cycle. 49 patients are evaluable for toxicity and 47 for efficacy after three months of treatment. Hematologic toxicity ...

journal_title：Anticancer research

authors： Misset JL,Metz R,Gil-Delgado M,Keiling R,Cappelaere P,Armand JP,Prévot G,Grimbert J,Mathé G,Hibberd M

更新日期：1987-07-01 00:00:00

abstract：AIM:This retrospective observational study evaluated the role of hypo-fractionated stereotactic radiotherapy (SRT) in patients with oligo-progressive metastatic renal cell carcinoma (mRCC) treated with first-line oral tyrosine kinase inhibitors (TKI). Data on local control, delay of further progression, and safety are ...

journal_title：Anticancer research

authors： Gebbia V,Girlando A,DI Grazia A,Fazio I,Borsellino N,Piazza D,Serretta V,Pergolizzi S,Pontoriero A,Firenze A,Valerio MR

更新日期：2020-12-01 00:00:00

abstract：AIM:To determine depression in patients with choroidal melanoma (CM) treated with proton beam radiotherapy. PATIENTS AND METHODS:This was a cross-sectional study including 50 patients with CM (50% males, mean age=49.88±6.34 years) and 46 age- and sex-matched healthy controls (52% males, mean age=48.60±8.05 years). Par...

journal_title：Anticancer research

authors： Moschos MM,Moustafa GA,Lavaris A,Damaskos C,Laios K,Karathanou E,Ladas DS,Asproudis I,Garmpis N,Kalogeropoulos C

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:Concurrent chemoradiotherapy with gemcitabine improves median survival for patients with unresectable pancreatic cancer. Recently, hyperfractionated accelerated radiotherapy (HART) has been used to treat these patients; however, the safety and efficacy are not well defined. PATIENTS AND METHODS:The standard...

journal_title：Anticancer research

authors： Maemura K,Shinchi H,Noma H,Mataki Y,Kurahara H,Maeda S,Hiraki Y,Nakajo M,Natsugoe S,Takao S

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:The possibilities and limitations of computer tomography (CT) examination for detecting primary gastric cancer tumors have been poorly understood. The aim of the present study was to evaluate the pre-operative assessment of gastric cancer tumors using 32-multidetector row-CT. PATIENTS AND METHODS:A prospect...

journal_title：Anticancer research

authors： Kikuchi S,Futawatari N,Sakuramoto S,Watanabe M,Kubota K,Sasaki M,Murata K,Kida M

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND/AIM:The Aspartate aminotransaminase/Alanine aminotransaminase ratio (AST/ALT ratio) has been identified as a prognostic marker for several malignancies. In this study, we evaluated the prognostic value of the AST/ALT ratio in a large cohort of non-metastatic colorectal cancer patients (CRC). PATIENTS AND ME...

journal_title：Anticancer research

authors： Scheipner L,Smolle MA,Barth D,Posch F,Stotz M,Pichler M,StÖger H,Gerger A,Riedl JM

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND/AIM:Orbital metastasis of systemic cancer is exceedingly rare. This is a case report of a patient treated for locally recurrent vulvar melanoma who later presented with unilateral proptosis and was found to have an isolated biopsy-proven extraocular muscle metastasis. PATIENTS AND METHODS:A 94-year-old fema...

journal_title：Anticancer research

authors： Pirlamarla AK,Tang J,Amin B,Kabarriti R

更新日期：2018-06-01 00:00:00

abstract：:Development of multidrug-resistance (MDR) remains a major cause of failure in the treatment of cancer with chemotherapeutic agents. In our efforts to explore alternative treatment regimens for multidrug-resistant tumors we have examined the sensitivity of MDR tumor cell lines to lymphokine activated killer (LAK) cells...

journal_title：Anticancer research

authors： Gautam SC,Chikkala NF,Lewis I,Grabowski DR,Finke JH,Ganapathi R

更新日期：1992-05-01 00:00:00

abstract：BACKGROUND:In a previous study we compared the influence of several growth factors on cancer cells in culture and observed that transforming growth factor-beta (TGF-beta) enhanced the invasiveness of several breast cancer cell lines. The objective of the present study was to determine the influence of three unique anti...

journal_title：Anticancer research

authors： Tong GM,Rajah TT,Zang XP,Pento JT

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Clofarabine is a second-generation nucleoside analogue. The aim of the study was the analysis of ex vivo activity of clofarabine and 14 other anticancer drugs in pediatric and adult acute lymphoblastic (ALL) and myeloid (AML) leukemia. PATIENTS AND METHODS:The ex vivo drug resistance profile was analyzed in...

journal_title：Anticancer research

authors： Styczynski J,Gil L,Derwich K,Wachowiak J,Balwierz W,Badowska W,Krawczuk-Rybak M,Matysiak M,Wieczorek M,Balcerska A,Sonta-Jakimczyk D,Stefaniak J,Kowalczyk J,Urasinski T,Sobol G,Komarnicki M,Wysocki M

更新日期：2009-05-01 00:00:00

abstract：:Treatment of patients with glioblastoma improved dramatically when concomitant and adjuvant temozolomide was added to external radiation therapy. The addition of this new treatment schedule as well as the improvements in individually-tailored radiation treatment, has resulted in a larger proportion of patients being f...

journal_title：Anticancer research

authors： Johansson F,Ekman S,Blomquist E,Henriksson R,Bergström S,Bergqvist M

更新日期：2012-09-01 00:00:00

abstract：:Important strategies against cancer are based on the understanding of the mechanisms of tumor progression. To elucidate alterations regarding tumor progression, we have performed proteomic differential display analysis for the expression of intracellular proteins in the regressive murine fibrosarcoma cell clone QR-32 ...

journal_title：Anticancer research

authors： Takenawa T,Kuramitsu Y,Wang Y,Okada F,Tokuda K,Kitagawa T,Ueyama Y,Nakamura K

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:To improve long-term survival by reducing toxicity in intermediate stage Hodgkin's disease patients, we compared the effects of involved field (IF) versus extended field (EF) irradiation administered after four cycles of ABVD regimen. MATERIALS AND METHODS:Two hundred and ten Hodgkin's disease patients, at ...

journal_title：Anticancer research

authors： Anselmo AP,Cavalieri E,Osti FM,Cantonetti M,De Sanctis V,Alfo M,Amadori S,Enrici RM

更新日期：2004-11-01 00:00:00

abstract：UNLABELLED:Platinum-based chemotherapy has been reported to induce diabetes and hyperosmolar coma in nondiabetic patients. The aim of the present study was to determine whether the administration of chemoradiation for head and neck carcinoma alters glucose metabolism during and after treatment. PATIENTS AND METHODS:We...

journal_title：Anticancer research

authors： Nguyen NP,Vos P,Vinh-Hung V,Borok TL,Dutta S,Karlsson U,Lee H,Martinez T,Jo BH,Nguyen LM,Nguyen N,Sallah S

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:A limited number of permanent ovarian carcinoma cell lines have been described so far and the majority of them have been derived from ovarian ascitic fluid cells taken from patients with serous ovarian carcinoma usually after chemotherapy treatment. MATERIALS AND METHODS:The cells for culture were obtained ...

journal_title：Anticancer research

authors： Bar JK,Harlozińska A

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND/AIM:Locoregional recurrence (LRR) of breast cancer is reported to occur at a rate of 5%-15%. Wide excision of LRR is the recommended treatment, which can increase the probability of subsequent local control. Herein, we describe a surgical technique wherein a pedicled skin and subcutaneous flap close the skin...

journal_title：Anticancer research

authors： Shinden Y,Nagata A,Nomoto Y,Saho H,Nakajo A,Minami K,Owaki T,Ohtsuka T,Kijima Y

更新日期：2020-10-01 00:00:00

abstract：:We report application of a novel immunohistochemical procedure for the staining of apoptotic (AP) cells in paraffin sections using monoclonal antibody (MAb) to single-stranded DNA. MAb differentiated between apoptosis and necrosis and in contrast to in situ end labelling specifically stained only AP cells. AP carcinom...

journal_title：Anticancer research

authors： Frankfurt OS,Robb JA,Sugarbaker EV,Villa L

更新日期：1996-07-01 00:00:00

abstract：BACKGROUND:The aim of this study was to investigate the diagnostic value of FDG PET in the follow-up for breast cancer in disease-free patients and patients suspected of having recurrent or metastatic disease. As a single imaging tool, PET can be compared with the conventional diagnostic means used for different examin...

journal_title：Anticancer research

authors： Siggelkow W,Zimny M,Faridi A,Petzold K,Buell U,Rath W

更新日期：2003-03-01 00:00:00

abstract：:The overexpression of p53, c-erbB-2 and p21ras gene products was evaluated immunohistochemically in ovarian carcinomas, borderline, and benign neoplasms. All studies were performed on cytospin preparations of cyst and/or ascitic fluid cells and mutual relations between oncoproteins were analysed. p53 and c-erbB-2 immu...

journal_title：Anticancer research

authors： Harłozińska A,Bar JK,Sobańska E,Goluda M

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND/AIM:Since the first description of five pericytomas with the t(7;12)/ACTB-GLI1 fusion gene, only three new tumors were studied by both cytogenetics and molecular techniques. We report here genetic data on another case of this rare tumor. MATERIALS AND METHODS:Cytogenetic, fluorescence in situ hybridization ...

journal_title：Anticancer research

authors： Panagopoulos I,Gorunova L,Rise TV,Andersen K,Micci F,Heim S

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND AND AIMS:We examined the prognostic value of pre-treatment C-reactive protein (CRP) after surgical resection (SR) for hepatocellular carcinoma (HCC). PATIENTS AND METHODS:A total of 298 patients with HCC who underwent SR were analyzed. They were categorized into a CRP-positive group (group A: CRP >0.2 mg/dl...

journal_title：Anticancer research

authors： Nishikawa H,Arimoto A,Wakasa T,Kita R,Kimura T,Osaki Y

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Because of the low chemosensitivity of gastric cancer to conventional antitumor agents, the role of adjuvant chemotherapy for patients with advanced gastric cancer is controversial. We have previously proposed the necessity to evaluate the appropriateness of particular adjuvant cancer chemotherapies in indiv...

journal_title：Anticancer research

authors： Kubota T,Egawa T,Otani Y,Furukawa T,Saikawa Y,Yoshida M,Watanabe M,Kumai K,Kitajima M

更新日期：2003-01-01 00:00:00