当前位置： SCI文献检索 > ANTICANCER RESEARCH期刊下所有文献 > Differences in breast carcinoma in situ between menopausal and premenopausal women.

Differences in breast carcinoma in situ between menopausal and premenopausal women.

Abstract：

AIM:To seek differences between ductal carcinoma in situ (DCIS) according to the menopausal status of patients and to analyze their repercussions on patient care. PATIENTS AND METHODS:A multicenter retrospective study of 384 patients from 3 centers specialized in breast cancer surgery was carried out based on an analysis of the various characteristics (clinical, therapeutic, histologic, outcome) of DCIS between two groups of post- and pre-menopausal patients. RESULTS:At the time of diagnosis, 58.6% of the patients were menopausal. Compared to these patients, DCIS in premenopausal women was more frequently associated with initial clinical signs (p=0.006), a larger tumor size (p=0.02), involved margins after initial surgery (p=0.005), and surgical re-excision (p=0.03). The mammograms of the menopausal patients indicated a worse prognosis (using the American College of Radiology Classification) (p=0.025), and according to the histology report findings, more marked comedo necrosis (p=0.01). There was no difference in the other criteria (nuclear grade, multifocality, benign lesions associated with malignancy, relapse and its time of occurrence). The use of hormone replacement therapy had no effect on these data. CONCLUSION:The characteristics of DCIS are similar, whether occuring before or after the menopause, but the phenotypic expression is different. Menopausal status should not be a criterion for changing patient care.

journal_name

Anticancer Res

journal_title

Anticancer research

authors

Pradier C,Cornuau M,Norca J,Mesbah H,Poree P,Body G,Classe JM,Leveque J

subject

Has Abstract

pub_date

2011-05-01 00:00:00

pages

1783-8

issue

5

eissn

0250-7005

issn

1791-7530

pii

31/5/1783

journal_volume

31

pub_type

杂志文章,多中心研究

相关文献

ANTICANCER RESEARCH文献大全
  • Generation of reactive oxygen intermediates (ROI) by the thionins from Viscum album L.

    abstract：BACKGROUND:Extracts from Viscum album L. are widely used as an adjuvant in complementary cancer therapy. While the mechanisms of mistletoe lectin (ML) cytotoxicity are well described, the viscotoxin (VT) effects are unclear at present. Thus, we treated human lymphocytes with VT and measured cell death-associated change...

    journal_title：Anticancer research

    pub_type： 杂志文章

    doi：

    authors： Büssing A,Schaller G,Pfüller U

    更新日期：1998-11-01 00:00:00

  • Non-tumorigenic SV40T immortalized human buccal epithelial cells show aneuploidy and genetic instability.

    abstract：:Cytogenetic and DNA flow cytometric analysis was carried out on four SV40T-transfected human buccal epithelial cells lines. One of these was immortalized and showed a nontumorigenic phenotype when tested in athymic nude mice. DNA flow cytometric ploidy values correlated well with cytogenetic ploidy values as calculate...

    journal_title：Anticancer research

    pub_type： 杂志文章

    doi：

    authors： Kulkarni Schmidt-Kastner PS,Heiden T,Tribukait B,Grafström RC

    更新日期：1996-09-01 00:00:00

  • Malignant mesothelioma of the tunica vaginalis testis in a petrochemical worker exposed to asbestos.

    abstract：:Malignant mesothelioma of the tunica vaginalis testis is a rare and aggressive asbestos-related malignancy that may pose difficult diagnostic problems. After 16 years of asbestos exposure, a 38-year-old petrochemical worker came to our notice with acute right testicular pain and swelling, simulating torsion of the spe...

    journal_title：Anticancer research

    pub_type： 杂志文章

    doi：

    authors： Candura SM,Canto A,Amatu A,Gerardini M,Stella G,Mensi M,Poggi G

    更新日期：2008-03-01 00:00:00

  • Regulation of Differentiation of HC11 Mouse Breast Epithelial Cells by the Signal Transducer and Activator of Transcription-3.

    abstract：BACKGROUND/AIM:The differentiation of the mouse breast epithelial cell line HC11 is known to require confluence as well as the addition of hydrocortisone, insulin and prolactin. MATERIALS AND METHODS:Since confluence, which triggers the engagement of the cell-to-cell adhesion molecule E-cadherin, induces a dramatic in...

    journal_title：Anticancer research

    pub_type： 杂志文章

    doi：10.21873/anticanres.13401

    authors： Niit M,Geletu M,Taha Z,Arulanandam R,Cass J,Hoskin V,Elliott B,Gunning P,Raptis L

    更新日期：2019-06-01 00:00:00

  • Lobarstin enhances chemosensitivity in human glioblastoma T98G cells.

    abstract：BACKGROUND/AIM:Lobarstin is a metabolite occurring from the Antarctic lichen Stereocaulon alpnum. Human glioblastoma is highly resistant to chemotherapy with temozolomide. Lobarstin was examined for its effect on glioblastoma. MATERIALS AND METHODS:Temozolomide-resistant T98G cells were subjected to toxicity test with...

    journal_title：Anticancer research

    pub_type： 杂志文章

    doi：

    authors： Kim S,Jo S,Lee H,Kim TU,Kim IC,Yim JH,Chung H

    更新日期：2013-12-01 00:00:00

  • 5-year results of cisplatin-epirubicin-vinorelbine (PEV) combination as primary chemotherapy in T2-3, N0-2 breast cancer patients: a multicentre phase II study.

    abstract：UNLABELLED:The aim this study was to assess the efficacy of cisplatin-epirubicin-vinorelbine, as primary chemotherapy, in reducing the tumour burden in T2-3 N0-2 breast carcinomas. Breast conservative surgery (BCS) rate, clinical and pathological complete response (pCR), toxicity and 5-year disease-free survival (DFS) ...

    journal_title：Anticancer research

    pub_type： 杂志文章,多中心研究

    doi：

    authors： Barni S,Visini M,Piazza E,Ionta MT,Ardizzoia A,Arnoldi E,Fava S,Pinotti G,Torretta F,Corradini G,Villa S,Nosenzo AM,Massidda B,Cazzaniga ME

    更新日期：2007-07-01 00:00:00

  • The effect of various types of splenectomy on the development of B-16 melanoma in mice.

    abstract：:260 CB57BL/J6 mice were used in an experimental protocol designed to investigate the effects of 4 different varieties of splenectomy on the growth rate of subcutaneously implanted GB-16 melanoma. In addition, the mean and absolute survival of the mice, the histopathology of the tumour and the effects of the same proce...

    journal_title：Anticancer research

    pub_type： 杂志文章

    doi：

    authors： Fotiadis C,Zografos G,Aronis K,Troupis TG,Gorgoulis VG,Sechas MN,Skalkeas G

    更新日期：1999-09-01 00:00:00

  • Retrovirus-mediated transduction of TRAIL and chemotherapeutic agents co-operatively induce apoptotic cell death in both sarcoma and myeloma cells.

    abstract：BACKGROUND:Resistance to multiple chemotherapeutic agents results from a variety of factors including a lack of apoptosis in tumor cells. To induce apoptosis in two types of tumor cells, RPMI-8226 and MG-63, a combination of chemotherapeutic agents and retroviral transduction of TRAIL was employed. MATERIALS AND METHO...

    journal_title：Anticancer research

    pub_type： 杂志文章

    doi：

    authors： Suzuki H,Hotta T,Koyama T,Komagata M,Imakiire A,Yanase N,Yoshimoto T,Mizuguchi J

    更新日期：2003-07-01 00:00:00

  • Detectable Wilms' tumor-1 transcription at treatment completion is associated with poor prognosis of acute myeloid leukemia: a single institution's experience.

    abstract：BACKGROUND/AIM:The present retrospective study was conducted to measure Wilms' tumor-1 (WT1) mRNA levels in the peripheral blood of patients with acute myeloid leukemia (AML) in order to examine any association with the clinical outcomes. PATIENTS AND METHODS:A total of 58 AML patients were evaluated retrospectively i...

    journal_title：Anticancer research

    pub_type： 杂志文章

    doi：

    authors： Yamauchi T,Negoro E,Lee S,Takai M,Matsuda Y,Takagi K,Kishi S,Tai K,Hosono N,Tasaki T,Ikegaya S,Yoshida A,Urasaki Y,Iwasaki H,Ueda T

    更新日期：2013-08-01 00:00:00

  • Up-regulation of DDX39 in human pancreatic cancer cells with acquired gemcitabine resistance compared to gemcitabine-sensitive parental cells.

    abstract：:Intrinsic or acquired resistance of pancreatic cancer to gemcitabine (2'-deoxy-2'-difluorodeoxycytidine) is an important factor in the failure of gemcitabine treatment. Proteomic analysis of gemcitabine-sensitive KLM1 pancreatic cancer cells and -resistant KLM1-R cells identified heat-shock protein-27(HSP27) as a biom...

    journal_title：Anticancer research

    pub_type： 杂志文章

    doi：

    authors： Kuramitsu Y,Suenaga S,Wang Y,Tokuda K,Kitagawa T,Tanaka T,Akada J,Maehara S,Maehara Y,Nakamura K

    更新日期：2013-08-01 00:00:00

  • MicroRNA Expression in KRAS- and BRAF-mutated Colorectal Cancers.

    abstract：BACKGROUND/AIM:KRAS and BRAF are two genes commonly mutated in colorectal cancer (CRC). Even though BRAF is a downstream target of KRAS in the MAPK signalling pathway, KRAS- and BRAF-mutated CRCs are found to display several different clinical and histopathological features. We investigated whether a differential expre...

    journal_title：Anticancer research

    pub_type： 杂志文章

    doi：10.21873/anticanres.12272

    authors： Lundberg IV,Wikberg ML,Ljuslinder I,Li X,Myte R,Zingmark C,Löfgren-Burström A,Edin S,Palmqvist R

    更新日期：2018-02-01 00:00:00

  • Prognostic significance of T helper 1 and 2 and T cytotoxic 1 and 2 cells in patients with non-small cell lung cancer.

    abstract：BACKGROUND:We report the prognostic significance of peripheral and tumor-infiltrating Th1, Th2, Tc1 and Tc2 cells in lung cancer patients. MATERIALS AND METHODS:We evaluated the rates of interferon (IFN)-gamma+/CD4+ cells (Th1), interleukin (IL)-4+ /CD4+ cells (Th2), IFN-gamma+/CD8+ cells (Tc1), IL-4+ /CD8+ cells (Tc2...

    journal_title：Anticancer research

    pub_type： 杂志文章

    doi：

    authors： Ito N,Suzuki Y,Taniguchi Y,Ishiguro K,Nakamura H,Ohgi S

    更新日期：2005-05-01 00:00:00

  • Activities of structurally-related lipophilic selenium compounds as cancer chemopreventive agents.

    abstract：:The present study compared the effects of four lipophilic forms of selenium with regard to cancer chemopreventive activity, tissue selenium accumulation, and bioavailability for synthesis of a selenoprotein. These reagents included methylphenyl selenide, diphenyl selenide, triphenyl-selenonium chloride, and p-xylylbis...

    journal_title：Anticancer research

    pub_type： 杂志文章

    doi：

    authors： Ip C,Lisk DJ,Ganther HE

    更新日期：1998-11-01 00:00:00

  • PROX1 Is Associated with Cancer Progression and Prognosis in Gastric Cancer.

    abstract：BACKGROUND:It was recently reported that expression of prospero homeobox protein-1 (PROX1) is correlated with the prognosis of esophageal cancer and colorectal cancer. However, its correlation with gastric cancer is unclear. MATERIALS AND METHODS:Our study analyzed the effect of PROX1 knockdown on the migration, invas...

    journal_title：Anticancer research

    pub_type： 杂志文章

    doi：10.21873/anticanres.12966

    authors： Ueta K,Otowa Y,Kakeji Y,Hirashima M

    更新日期：2018-11-01 00:00:00

  • Interaction of radiation and etoposide on two cell lines with different radiosensitivities in vitro.

    abstract：PURPOSE:To investigate the differences between two rat yolk sac tumor cell lines with different radiosensitivities in etoposide sensitivity and in the sensitizing effect of etoposide in combination with irradiation. MATERIALS AND METHODS:NMT-1 is a parent radiosensitive cell line and NMT-1R is a variant radioresistant...

    journal_title：Anticancer research

    pub_type： 杂志文章

    doi：

    authors： Takahashi T,Mitsuhashi N,Akimoto T,Matsumoto H,Ishikawa H,Saito Y,Niibe H

    更新日期：2003-07-01 00:00:00

  • Clinical Significance of Glioma-associated Oncogene 1 Expression in Patients With Locally Advanced Gastric Cancer Administered Adjuvant Chemotherapy With S-1 After Curative Surgery.

    abstract：BACKGROUND/AIM:Glioma-associated oncogene 1 (GLI1) is an important transcription factor in the hedgehog signalling pathway and tumour formation. We evaluated the clinical significance of GLI1 expression as a prognostic factor in patients with locally advanced gastric cancer (GC). PATIENTS AND METHODS:GLI1 expression l...

    journal_title：Anticancer research

    pub_type： 杂志文章

    doi：10.21873/anticanres.14599

    authors： Hashimoto I,Oue N,Kimura Y,Hiroshima Y,Hara K,Maezawa Y,Kano K,Fujikawa H,Aoyama T,Numata M,Yamada T,Tamagawa H,Yamamoto N,Ogata T,Shiozawa M,Morinaga S,Rino Y,Yasui W,Masuda M,Miyagi Y,Oshima T

    更新日期：2020-10-01 00:00:00

  • Comparative anti-inflammatory activities of curcumin and tetrahydrocurcumin based on the phenolic O-H bond dissociation enthalpy, ionization potential and quantum chemical descriptor.

    abstract：:Curcumin and its reduced derivative tetrahydrocurcumin have been shown to exhibit chemopreventive activity. Cyclooxygenase-2 (COX-2) inhibition in lipopolysaccharide (LPS)- or Porphyromonas gingivalis fimbria-stimulated RAW 264.7 cells was investigated using Northern blot analysis. The fimbria-stimulated expression of...

    journal_title：Anticancer research

    pub_type： 杂志文章

    doi：

    authors： Murakami Y,Ishii H,Takada N,Tanaka S,Machino M,Ito S,Fujisawa S

    更新日期：2008-03-01 00:00:00

  • Structure-activity relationships of alpha, beta-unsaturated ketones as assessed by their cytotoxicity against oral tumor cells.

    abstract：:A series of simple alpha, beta-unsaturated carbonyl compounds (1-26) was characterized for their cytotoxic profiles against oral human normal and tumor cells. Several cycloalkenones showed potent cytotoxic activities against human oral squamous cell carcinoma HSC-2 cell line. Among them, 4,4-dimethyl-2-cyclopenten-1-o...

    journal_title：Anticancer research

    pub_type： 杂志文章

    doi：

    authors： Nakayachi T,Yasumoto E,Nakano K,Morshed SR,Hashimoto K,Kikuchi H,Nishikawa H,Kawase M,Sakagami H

    更新日期：2004-03-01 00:00:00

  • Combined treatment with thymosin-alpha1 and low-dose interferon-alpha after ifosfamide in non-small cell lung cancer: a phase-II controlled trial.

    abstract：:22 patients with advanced non-small-cell lung cancer were randomized to receive chemotherapy (ifosfamide) or chemotherapy followed by thymosin alpha1 + low-dose IFNalpha. Chemo-immunotherapy induced an enhanced response rate compared with chemotherapy alone (33% and 10% respectively). Although these differences were n...

    journal_title：Anticancer research

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：

    authors： Salvati F,Rasi G,Portalone L,Antilli A,Garaci E

    更新日期：1996-03-01 00:00:00

  • Combination of Trabectedin With Irinotecan, Leucovorin and 5-Fluorouracil Arrests Primary Colorectal Cancer in an Imageable Patient-derived Orthotopic Xenograft Mouse Model.

    abstract：BACKGROUND/AIM:The aim of the present study was to determine the efficacy of trabectedin combined with FOLFIRI (irinotecan, leucovorin and 5-fluorouracil) on a colorectal cancer (CRC) patient-derived orthotopic xenograft (iPDOX) mouse model. MATERIALS AND METHODS:A CRC tumor from a patient previously established in nu...

    journal_title：Anticancer research

    pub_type： 杂志文章

    doi：10.21873/anticanres.13860

    authors： Zhu G,Zhao M,Han Q,Tan Y,Sun YU,Bouvet M,Clary B,Singh SR,Ye J,Hoffman RM

    更新日期：2019-12-01 00:00:00

  • Topoisomerase II alpha expression in esophageal squamous cell carcinoma.

    abstract：BACKGROUND:DNA topoisomerase II alpha (topo II alpha) is associated with active cell proliferation of mammalian cells. Topo II alpha overexpression has been reported in a number of human malignancies and is considered to be related to their biological behaviors. MATERIALS AND METHODS:We examined the expression of topo...

    journal_title：Anticancer research

    pub_type： 杂志文章

    doi：

    authors： Ohashi Y,Sasano H,Yamaki H,Shizawa S,Kikuchi A,Shineha R,Akaishi T,Satomi S,Nagura H

    更新日期：1999-05-01 00:00:00

  • Human Papillomavirus and Potentially Relevant Biomarkers in Tonsillar and Base of Tongue Squamous Cell Carcinoma.

    abstract：:Human papillomavirus (HPV)-positive tonsillar- and base of tongue cancer is increasing epidemically and has much better outcome than corresponding HPV-negative cancer and most other head and neck cancers with around 80% 3-year disease free survival with conventional radiotherapy and surgery. Consequently, most HPV-pos...

    journal_title：Anticancer research

    pub_type： 杂志文章,评审

    doi：10.21873/anticanres.11958

    authors： Näsman A,Bersani C,Lindquist D,Du J,Ramqvist T,Dalianis T

    更新日期：2017-10-01 00:00:00

  • Clinical Value of Serum p53 Antibody in the Diagnosis and Prognosis of Esophageal Squamous Cell Carcinoma.

    abstract：BACKGROUND/AIM:Identifying useful biomarkers is central to selecting optimal therapeutic strategies for esophageal squamous cell carcinoma (ESCC). Serum p53 antibody (S-p53Ab), squamous cell carcinoma antigen (SCC-Ag), and carcinoembryonic antigen (CEA) were investigated to evaluate the significance of single and combi...

    journal_title：Anticancer research

    pub_type： 杂志文章

    doi：10.21873/anticanres.12419

    authors： Kunizaki M,Hamasaki K,Wakata K,Tobinaga S,Sumida Y,Hidaka S,Yasutake T,Miyazaki T,Matsumoto K,Yamasaki T,Sawai T,Hamamoto R,Nanashima A,Nagayasu T

    更新日期：2018-03-01 00:00:00

  • Genetic polymorphisms of carcinogen metabolizing enzymes are associated with oral leukoplakia development and p53 overexpression.

    abstract：BACKGROUND:Genetic polymorphisms of carcinogen-metabolizing enzyme genes have been associated with the risk of oral squamous cell carcinoma and oral leukoplakia. The overexpression of p53 protein is the most common genetic alteration in head and neck cancer. In the present study the combined or isolated presence of glu...

    journal_title：Anticancer research

    pub_type： 杂志文章

    doi：

    authors： Duarte EC,Ribeiro DC,Gomez MV,Ramos-Jorge ML,Gomez RS

    更新日期：2008-03-01 00:00:00

  • Lack of correlation between P53 expression, BCL-2 expression, apoptosis and ex vivo chemosensitivity in advanced human breast cancer.

    abstract：:The relationship between apoptosis and chemosensitivity remains complex. We tested the chemosensitivity of 45 patients with advanced breast cancer (BC) ex vivo against anthracyclines (A: doxorubicin, epirubicin), taxanes (T: paclitaxel, docetaxel), cisplatin (DDP) and CMF and any correlation with the expression of p53...

    journal_title：Anticancer research

    pub_type： 杂志文章

    doi：

    authors： Rein DT,Schöndorf T,Breidenbach M,Janát MM,Weikelt A,Göhring UJ,Becker M,Mallmann P,Kurbacher CM

    更新日期：2000-11-01 00:00:00

  • Upfront Surgery for Small Intestinal Non-Hodgkin's Lymphoma.

    abstract：BACKGROUND/AIM:The clinical significance of surgery for secondary small intestinal non-Hodgkin's lymphomas (NHL) remains unknown. This study aimed to investigate the efficacy of resection for both primary and secondary small intestinal NHL. PATIENTS AND METHODS:Twenty patients with small intestinal lymphoma who underw...

    journal_title：Anticancer research

    pub_type： 杂志文章

    doi：10.21873/anticanres.14206

    authors： Iida T,Nozawa H,Sonoda H,Toyama K,Kawai K,Hata K,Tanaka T,Nishikawa T,Sasaki K,Shuno Y,Kaneko M,Murono K,Emoto S,Ishii H,Kurokawa M,Ishihara S

    更新日期：2020-04-01 00:00:00

  • Evaluation of Follow-up Examinations Using Ultrasonography for Patients With Thyroid Nodules Initially Diagnosed as Benign.

    abstract：BACKGROUND/AIM:The aim of this study was to determine the natural history of benign thyroid nodules using ultrasonography. PATIENTS AND METHODS:The records of 223 patients with benign thyroid nodules treated at the Kochi Medical School from 2010 to 2012 were reviewed retrospectively. Repeated ultrasonography was perfo...

    journal_title：Anticancer research

    pub_type： 杂志文章

    doi：10.21873/anticanres.13317

    authors： Oki T,Sugimoto T,Ogawa M,Dabanaka K,Namikawa T,Hanazaki K

    更新日期：2019-04-01 00:00:00

  • Cytotoxicity of CPT-11 and SN-38 for gastrointestinal and recurrent carcinomas cultured on contact-sensitive plates.

    abstract：:CPT-11 is a derivative of camptothecin, a topoisomerase-I inhibitor with marked cytotoxic activity. We examined the cytotoxicity of CPT-11 and its metabolite SN-38 for primary gastrointestinal carcinoma and various recurrent carcinomas which were cultured on contact-sensitive plates (CSPs). The response rate of seven ...

    journal_title：Anticancer research

    pub_type： 杂志文章

    doi：

    authors： Matsuoka H,Furusawa M,Tomoda H,Seo Y,Kono A,Takeda S,Sato K

    更新日期：1994-03-01 00:00:00

  • Natural antibodies against the carcinoembryonic antigen (CEA) and a related antigen, NCA, in human sera.

    abstract：:Natural antibodies directed against CEA and a related antigen, NCA, have been demonstrated in all normal and pathological sera using an EIA, although they have never been detected by RIA. These antibodies are not anti-blood group antibodies, as their titer was decreased only slightly by absorption with blood group sub...

    journal_title：Anticancer research

    pub_type： 杂志文章

    doi：

    authors： Frénoy N,Schauffler J,Cahour A,Burtin P

    更新日期：1987-11-01 00:00:00

  • The effect of a biological response modifier, PSK, on the intestinal immune system in tumor-bearing mice.

    abstract：:We have previously shown that oral administration of PSK not only exerts antitumor activity, but also restores immune response in tumor-bearing mice. In order to analyze the immunomodulative effect of PSK, we investigated the effects of oral PSK on the intestinal immune systems in ICR mice bearing sarcoma 180. Oral ad...

    journal_title：Anticancer research

    pub_type： 杂志文章

    doi：

    authors： Matsunaga K,Morita I,Oguchi Y,Fujii T,Yoshikumi C,Nomoto K

    更新日期：1987-05-01 00:00:00