Abstract：
UNLABELLED:Platinum-based chemotherapy has been reported to induce diabetes and hyperosmolar coma in nondiabetic patients. The aim of the present study was to determine whether the administration of chemoradiation for head and neck carcinoma alters glucose metabolism during and after treatment. PATIENTS AND METHODS:Weekly nonfasting serum glucose level was obtained during treatment of one hundred and six patients with locally advanced head and neck cancer who underwent chemoradiationt. RESULTS:For the 91 non-diabetic patients, mean serum glucose level measured 97.75 before and 102.1, 102, 104.1, 109.1, 109.7, 110.3, 109.8, 113.2, 107.7 and 104.3 mg/dl during weeks 1-10 of treatment respectively. Serum glucose level elevation reached statistical significance for weeks 5-8. CONCLUSION:Chemoradiation for head and neck cancer may produce severe glucose metabolism alteration during treatment.
journal_name
Anticancer Resjournal_title
Anticancer researchauthors
Nguyen NP,Vos P,Vinh-Hung V,Borok TL,Dutta S,Karlsson U,Lee H,Martinez T,Jo BH,Nguyen LM,Nguyen N,Sallah Ssubject
Has Abstractpub_date
2009-11-01 00:00:00pages
4683-7issue
11eissn
0250-7005issn
1791-7530pii
29/11/4683journal_volume
29pub_type
杂志文章abstract：BACKGROUND:C-reactive protein (CRP) is the prototypical biomarker of inflammation. Genetic variations within the CRP gene have been shown to be associated with alterations of CRP expression and prognosis in cancer patients. The purpose of this study was to evaluate the association between four polymorphisms of the CRP ...
journal_title：Anticancer research
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更新日期：1993-07-01 00:00:00
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更新日期：2012-10-01 00:00:00
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journal_title：Anticancer research
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更新日期：2014-08-01 00:00:00
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更新日期：2012-12-01 00:00:00
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journal_title：Anticancer research
pub_type： 杂志文章
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更新日期：2002-05-01 00:00:00
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doi：
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doi：
更新日期：2002-11-01 00:00:00
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journal_title：Anticancer research
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doi：
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doi：
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journal_title：Anticancer research
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doi：
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更新日期：1992-09-01 00:00:00
