Association of C-reactive protein (CRP) gene polymorphisms, serum CRP levels and cervical cancer prognosis.

abstract：:Two metastasis-associated proteins, CD44v6 and NM23-H1, are expressed by normal lymphoid cells, the former serving as activation marker and the latter as a constitutive protein. CD44v6 is considered as a marker of poor prognosis of various hematological cancers but its expression was not demonstrated in childhood acut...

journal_title：Anticancer research

authors： Magyarosy E,Sebestyén A,Timár J

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Gastric cancer is the third most frequent type of neoplasia. In northern Brazil, the State of Pará has a high incidence of this type of neoplasia. Limited data are available so far on the genetic events involved in this disease. MATERIALS AND METHODS:Dual-color fluorescence in situ hybridization (FISH) for ...

journal_title：Anticancer research

authors： Calcagno DQ,Leal MF,Taken SS,Assumpção PP,Demachki S,Smith Mde A,Burbano RR

更新日期：2005-11-01 00:00:00

abstract：UNLABELLED:In a previous report we noted that cyclooxygenase-2 (COX-2) expression in clinical colorectal cancer is closely related to liver metastasis and survival. The aim of the present study was to clarify the role of COX-2 in liver metastasis and to examine the potential for a selective COX-2 inhibitor as a novel t...

journal_title：Anticancer research

authors： Yamauchi T,Watanabe M,Hasegawa H,Nishibori H,Ishii Y,Tatematsu H,Yamamoto K,Kubota T,Kitajima M

更新日期：2003-01-01 00:00:00

abstract：:We examined the antitumor effect of lipopolysaccharide extracted from Pantoea agglomerans, a Gram-negative bacterium, using intradermal administration on murine syngeneic tumors, Meth A fibrosarcoma, MH134 hepatoma and Lewis lung (LL) carcinoma. The latter two tumors are known to be relatively low in immunogenicity, h...

journal_title：Anticancer research

authors： Inagawa H,Nishizawa T,Noguchi K,Minamimura M,Takagi K,Goto S,Soma G,Mizuno D

更新日期：1997-05-01 00:00:00

abstract：:As with SV40-transformed BHK cells (1), pretreatment of BHK cells with 1-beta-D-arabinofuranosylcytosine (araC) very markedly enhanced the resistance frequency to N-phosphonoacetyl-L-aspartate (PALA) but only modestly increased the resistance frequency to vincristine (VCR). AraC pretreatment of cells that already had ...

journal_title：Anticancer research

authors： Chen Y,Goz B,Kirkman L

更新日期：1993-01-01 00:00:00

abstract：:p73, a structural homologue of the tumor suppressor gene, p53, has recently been identified and mapped to chromosome 1p36, where genomic loss of heterozygosity (LOH) often occurs in human hepatocellular carcinoma (HCC). To determine whether p73 is involved in the development of HCC and whether there is an inverse corr...

journal_title：Anticancer research

authors： Peng CY,Tsai SL,Yeh CT,Hung SP,Chen MF,Chen TC,Chu CM,Liaw YF

更新日期：2000-05-01 00:00:00

abstract：:Evidence exists that estrogen metabolism has a role in the pathogenesis of recurrent respiratory papillomatosis (RRP). This disease has a papillomavirus etiology and is characterized by recurrent benign tumors with a significant propensity to become malignant. We have measured the systemic transformation of estrogen u...

journal_title：Anticancer research

authors： Auborn K,Abramson A,Bradlow HL,Sepkovic D,Mullooly V

更新日期：1998-11-01 00:00:00

abstract：AIM:The aim of the present study was to detect the relative expressions of p53, p21(Waf1/Cip1), p27(Kip1) Bcl-2 and cleaved caspase-3 in cervical lesion samples from Brazilian women by immunohistochemistry. MATERIALS AND METHODS:A total of 230 cervical biopsies in paraffin-embedded blocks were studied: 43 were invasiv...

journal_title：Anticancer research

authors： Dobo C,Oshima CT,De Oliveira Lima F,Gomes TS,Stávale JN,Arias V,Ribeiro DA,Focchi GR

更新日期：2014-06-01 00:00:00

abstract：UNLABELLED:BACKGROND/AIM: Recent evidence indicates that inflammation is a hallmark of cancer. Tumor-associated neutrophils (TANs) contribute to tumor invasion. However, whether TANs and lymph node metastasis are related is unknown. Intranodal lymphatic vessel density (LVD) is significantly correlated with tumor progre...

journal_title：Anticancer research

authors： Tokumoto M,Tanaka H,Ohira M,Go Y,Okita Y,Sakurai K,Toyokawa T,Kubo N,Muguruma K,Maeda K,Sawada T,Hirakawa K

更新日期：2014-12-01 00:00:00

abstract：:2-Amino-3-methylimidazo[4,5-f]quinoline (IQ) is a food mutagen which has been found to be carcinogenic in the Fischer-344 rat. We have assessed the effects of a diet containing menhaden oil on IQ-DNA adduct formation in several organs of the male Fischer-344 rat. Young adult, male Fischer-344 rats were maintained on e...

journal_title：Anticancer research

authors： Schut HA

更新日期：1993-09-01 00:00:00

abstract：:The metabolic transformations of labeled pyridoxine by hepatoma cells were studied. Buffalo rats were fed ad libitum a commercially prepared pyridoxine sufficient diet for 20 days at which time they were inoculated intramuscularly with hepatoma 7777 cells in both hind leg muscles. After tumor development, 50 microCi [...

journal_title：Anticancer research

authors： Tryfiates GP

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND/AIM:Combining an anticancer agent fenretinide (HPR) or C6-pyridinium ceramide (LCL29) with Foscan-mediated photodynamic therapy (FoscanPDT) is expected to augment anticancer benefits of each substance. We showed that treatment with FoscanPDT+HPR enhanced accumulation of C16-dihydroceramide, and that fumonisi...

journal_title：Anticancer research

authors： Boppana NB,Kraveka JM,Rahmaniyan M,Li LI,Bielawska A,Bielawski J,Pierce JS,Delor JS,Zhang K,Korbelik M,Separovic D

更新日期：2017-02-01 00:00:00

abstract：:A pharmacologically relevant modelling was attempted for screening of new molecules potentially active against non-small-cell lung cancers (NSCLCs). It was in this way that we investigated the in vivo chemosensitivity firstly of three human NSCLCs grafted onto nude mice, secondly of their in vitro primocultures, and t...

journal_title：Anticancer research

authors： Kruczynski A,Kiss R

更新日期：1993-03-01 00:00:00

abstract：BACKGROUND/AIM:Seizures represent a major problem for patients with brain metastases. This study evaluated the role of seizures in patients receiving single-fraction radiosurgery (SRS) or multi-fraction stereotactic radiotherapy (FSRT). PATIENTS AND METHODS:This retrospective study included 195 patients receiving SRS ...

journal_title：Anticancer research

authors： Rades D,Witteler J,Kjaer TW,Tvilsted S,Schild SE

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND/AIM:Prognosis for patients with head and neck squamous cell carcinoma (HNSCC) is poor in most cases and has not improved despite advances in therapy. Novel therapeutic approaches are mandatory in order to improve the situation. Everolimus, an inhibitor of mammalian target of rapamycin, as well as the multi-t...

journal_title：Anticancer research

authors： Aderhold C,Faber A,Umbreit C,Chakraborty A,Bockmayer A,Birk R,Sommer JU,Hörmann K,Schultz JD

更新日期：2015-03-01 00:00:00

abstract：:The mouse/human chimeric antibody Ch F11-39, recently generated by ourselves, shows the same high specificity and affinity for carcinoembryonic antigen (CEA) as those of its parental mouse monoclonal antibody. Ch F11-39 is capable of mediating antibody-dependent cell-mediated cytotoxicity (ADCC) with human peripheral ...

journal_title：Anticancer research

authors： Senba T,Kuroki M,Arakawa F,Yamamoto T,Kuwahara M,Haruno M,Ikeda S,Matsuoka Y

更新日期：1998-01-01 00:00:00

abstract：:The incorporation and metabolism of delta-6-desaturase substrate and product, [1-14C]-linoleic (18:2n-6) and [1-14C]-gamma-linolenic acid (18:3n-6), was examined in NIH-3T3 cells and the DT subclone which differs only in the presence of the v-Ki-ras oncogene. Similar amounts of post delta-6 and delta-5 desaturase meta...

journal_title：Anticancer research

authors： De Antueno RJ,Cantrill RC,Ells GW,Elliot M,Huang YS,Horrobin DF

更新日期：1993-07-01 00:00:00

abstract：AIM:To investigate the discordance in the programmed cell death-ligand 1 (PD-L1) expression between primary and metastatic tumors and analyze the association between the discordance and the clinical factors in non-small cell lung cancer (NSCLC) patients. PATIENTS AND METHODS:Twenty-one NSCLC patients who underwent sur...

journal_title：Anticancer research

authors： Takamori S,Toyokawa G,Okamoto I,Takada K,Kozuma Y,Matsubara T,Haratake N,Akamine T,Katsura M,Mukae N,Shoji F,Okamoto T,Oda Y,Iwaki T,Iihara K,Nakanishi Y,Maehara Y

更新日期：2017-08-01 00:00:00

abstract：:A rat rhabdomyosarcoma clonal line RMS/8 was cotransfected with genomic DNA of procaryotic or eucaryotic origin and neomycin resistance plasmid pKOneo. The lung colonizing and metastatic capacity of transfected cells was evaluated. When col- meta- RMS/8 cells were transfected, an increase in lung colonizing but not in...

journal_title：Anticancer research

authors： Verrelle P,Lascaut V,Poupon MF,Hillova J

更新日期：1987-03-01 00:00:00

abstract：:Menogaril is an antitumor agent active after oral administration, and unlike other anthracyclines, extravasation cannot occur. When the IC90 values of menogaril were plotted versus exposure time on a double-logarithmic scale, the regression lines had slopes between -0.64 and -0.80. These results showed that the mode o...

journal_title：Anticancer research

authors： Yoshida M,Kobunai T,Nakano K,Saito H,Toko T,Takeda S,Unemi N

更新日期：1996-09-01 00:00:00

abstract：OBJECTIVE:To evaluate the existence of an association between cervicovaginal infections and precancerous lesions of the uterine cervix, through determination of prevalent cervicovaginal micro-organisms, alone and in association with human papillomavirus (HPV), in patients with abnormal and normal vaginal cytology. PAT...

journal_title：Anticancer research

authors： Lukic A,Canzio C,Patella A,Giovagnoli M,Cipriani P,Frega A,Moscarini M

更新日期：2006-11-01 00:00:00

abstract：:We examined the influence of a regularly moderate endurance training program on qualitative and quantitative alterations of monocytes from 24 breast cancer patients. At the beginning, after 5 weeks and 7 months of bicycle training we analyzed the composition of leucocytes and phagocytotic activity of monocytes using t...

journal_title：Anticancer research

authors： Peters C,Lötzerich H,Niemeir B,Schüle K,Uhlenbruck G

更新日期：1995-01-01 00:00:00

abstract：:Single agent carboplatin has demonstrated antitumoral activity in patients with advanced breast cancer. Thirty patients with inoperable locally advanced and/or metastatic breast cancer were treated with carboplatin (300 mg/m2) in combination with cyclophosphamide (600 mg/m2) and 5-fluorouracil (500 mg/m2) given on day...

journal_title：Anticancer research

authors： Closon MT,Verbeke L,Kains JP,Tijtgat J,Schallier D

更新日期：1995-03-01 00:00:00

abstract：BACKGROUND/AIM:Recent studies implied a significant role of hypoxia-inducible factor-1α (HIF1α) in cell transformation. This study aimed to assess the effects of HIF1α on the epithelial-to-mesenchymal transition (EMT) and tumorigenesis of lung adenocarcinoma cells. MATERIALS AND METHODS:Invasion, migration and colony ...

journal_title：Anticancer research

authors： Liu KH,Tsai YT,Chin SY,Lee WR,Chen YC,Shen SC

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:The aim of this study was to develop and characterize a mouse xenograft model for the hypercalcemic-type of small cell carcinoma of the ovary (HTSCCO). PATIENTS AND METHODS:Tumor fragments were removed from a patient and cultured in six subsequent generations of nude mice. Histology, comparative genomic hyb...

journal_title：Anticancer research

authors： Walt H,Hornung R,Fink D,Dobler-Girdziunaite D,Stallmach T,Spycher MA,Maly F,Haller U,Bürki N

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:The knowledge of direct effects of β-glucans on tumor cells is limited. This study evaluated the impact of a soluble yeast-derived beta-(1-3),(1-6)-d-glucan, containing a fraction of aggregated sugar polymers, on viability, proliferation and expression of CD86 of the human B-cell lymphoma cell lines Daudi an...

journal_title：Anticancer research

authors： Harnack U,Kellermann U,Pecher G

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:The size of colorectal polyps is important in the clinical management of these lesions. When using a conventional ruler (the tool of pathologists worldwide), we have previously found unacceptably high intra- and inter-observer variations in assessing the size of phantom polyps. The aim of this study was to a...

journal_title：Anticancer research

authors： Suzuki C,Matsson L,Rubio CA

更新日期：2008-05-01 00:00:00

abstract：:Human vaginal malignant melanoma represents rare gynecological malignancies of poor prognosis. We have established a melanoma tumor line in nude mice, designated Mela-1, and have examined the histological and biological characteristics of this tumor. The Mela-1 tumor has preserved the histological, histochemical and b...

journal_title：Anticancer research

authors： Sawada M,Terada N,Nishizawa Y,Ito S,Wakamatsu K,Takemura K,Yamamoto T,Ozaki M,Sakamoto H,Tanizawa O

更新日期：1994-07-01 00:00:00

abstract：:AD 198, a novel lipophilic N-alkyl derivative of adriamycin (ADR) and a potential anticancer agent for preclinical development, was studied for its effects on the activities of DNA and RNA polymerases in vitro and its ability to bind DNA. AD 198, which contains a benzyl substituent on the glycosidic amine, was found t...

journal_title：Anticancer research

authors： Lameh J,Chuang LF,Israel M,Chuang RY

更新日期：1988-07-01 00:00:00

abstract：BACKGROUND:Preclinical studies have shown that paclitaxel and doxifluridine can act synergistically without overlapping toxicity for the treatment of advanced gastric cancer. The objectives of this study were to determine the maximum tolerated dose (MTD), the dose-limiting toxicity and the recommended Phase II dose for...

journal_title：Anticancer research

authors： Takeyoshi I,Makita F,Tanahashi Y,Yokomori T,Iwazaki S,Kawashima Y,Iwanami K,Yamada T,Kawate S,Hamada K,Sunose Y,Yoshida M,Horiguchi J,Iesato H,Kobayashi M,Morishita Y

更新日期：2005-03-01 00:00:00