Rapid development of synaptic connections and plasticity between sensory neurons and motor neurons of Aplysia in cell culture: implications for learning and regulation of synaptic strength.

abstract：:1. Using patch-clamp recordings, expression of voltage-activated ion channels by identified glial cells in situ was studied in hippocampal slices derived from 5- to 24-day-old rats. Glial cells were filled with Lucifer yellow during recording, and were identified by staining for glial fibrillary acidic protein (GFAP)....

journal_title：Journal of neurophysiology

authors： Sontheimer H,Waxman SG

更新日期：1993-11-01 00:00:00

abstract：:In a subset of hereditary retinal diseases, early photoreceptor degeneration causes rapidly progressive blindness in children. To better understand how retinal development may interact with degenerative processes, we compared spontaneous and light-evoked activity among retinal ganglion cells in rd1 and rd10 mice, stra...

journal_title：Journal of neurophysiology

authors： Stasheff SF,Shankar M,Andrews MP

更新日期：2011-06-01 00:00:00

abstract：:At many glutamatergic synapses, non-N-methyl-d-aspartate (NMDA) and NMDA receptors are coexpressed postsynaptically. In the mammalian retina, glutamatergic rod bipolar cells are presynaptic to two rod amacrine cells (AII and A17) that constitute dyad postsynaptic partners opposite each presynaptic active zone. Whereas...

journal_title：Journal of neurophysiology

authors： Zhou Y,Tencerová B,Hartveit E,Veruki ML

更新日期：2016-01-01 00:00:00

abstract：:1. Ionic conductances controlled by type A and type B cholecystokinin (CCK) receptors were studied in neurons of the rat nucleus tractus solitarius (NTS) and dorsal motor nucleus of the vagus (DMNV), using intracellular and whole-cell patch clamp recordings in current or voltage clamp configuration during bath applica...

journal_title：Journal of neurophysiology

authors： Branchereau P,Champagnat J,Denavit-Saubié M

更新日期：1993-12-01 00:00:00

abstract：:Fluorescent protein (XFP) expression in postnatal neurons allows the anatomical and physiological investigation of identified subpopulations of interneurons with established techniques. However, the spatiotemporal pattern of activity of these XFP neurons within a network and their role in the functional output of the ...

journal_title：Journal of neurophysiology

authors： Wilson JM,Dombeck DA,Díaz-Ríos M,Harris-Warrick RM,Brownstone RM

更新日期：2007-04-01 00:00:00

abstract：:The development of modern neuroscience tools is critical for deciphering brain circuit organization and function. An important aspect for technical development is to enhance each technique's advantages and compensate for limitations. We developed a high-precision and fast functional mapping technique in brain slices t...

journal_title：Journal of neurophysiology

authors： Xu X,Olivas ND,Levi R,Ikrar T,Nenadic Z

更新日期：2010-04-01 00:00:00

abstract：:1. High-threshold Ca2+ currents were studied in large pyramidal cells acutely dissociated from the rat amygdaloid complex. L-, N-, and P-type currents were present in about equal proportions in these cells and accounted for most of the whole-cell current. ...

journal_title：Journal of neurophysiology

authors： Foehring RC,Scroggs RS

更新日期：1994-01-01 00:00:00

abstract：:Understanding how the brain processes sensory input to generate behavior remains an important problem in neuroscience. Towards this end, it is useful to compare results obtained across multiple species to gain understanding as to the general principles of neural coding. Here we investigated hindbrain pyramidal cell ac...

journal_title：Journal of neurophysiology

authors： Martinez D,Metzen MG,Chacron MJ

更新日期：2016-12-01 00:00:00

abstract：:Visual tracking of moving targets requires the combination of smooth pursuit eye movements with catch-up saccades. In primates, catch-up saccades usually take place only during pursuit initiation because pursuit gain is close to unity. This contrasts with the lower and more variable gain of smooth pursuit in cats, whe...

journal_title：Journal of neurophysiology

authors： de Brouwer S,Missal M,Lefèvre P

更新日期：2001-08-01 00:00:00

abstract：:Muscle spindles provide exquisitely sensitive proprioceptive information regarding joint position and movement. Through passively driven length changes in the muscle-tendon unit (MTU), muscle spindles detect joint rotations because of their in-parallel mechanical linkage to muscle fascicles. In human microneurography ...

journal_title：Journal of neurophysiology

authors： Day J,Bent LR,Birznieks I,Macefield VG,Cresswell AG

更新日期：2017-04-01 00:00:00

abstract：:Few studies have analyzed activity-induced changes in EMG activity in individual human motor units. We studied the changes in human thenar motor unit EMG that accompany the potentiation of twitch force and fatigue of tetanic force. Single motor unit EMG and force were recorded in healthy subjects in response to select...

journal_title：Journal of neurophysiology

authors： Thomas CK,Johansson RS,Bigland-Ritchie B

更新日期：2006-03-01 00:00:00

abstract：:Electrical transmission is a dynamically regulated form of communication and key to synchronizing neuronal activity. The bag cell neurons of Aplysia are a group of electrically coupled neuroendocrine cells that initiate ovulation by secreting egg-laying hormone during a prolonged period of synchronous firing called th...

journal_title：Journal of neurophysiology

authors： Dargaei Z,Standage D,Groten CJ,Blohm G,Magoski NS

更新日期：2015-02-01 00:00:00

abstract：:In this report, we provide the first characterization of abducens nucleus neuron (ABN) discharge dynamics during horizontal disjunctive saccades. These movements function to rapidly transfer the visual axes between targets located at different eccentricities and depths. Our primary objective was to determine whether t...

journal_title：Journal of neurophysiology

authors： Sylvestre PA,Cullen KE

更新日期：2002-12-01 00:00:00

abstract：:1. The aim of this study was to examine the nature of motoneuron firing-rate modulation in type-identified motor units during smoothly graded contractions of the cat medial gastrocnemius (MG) muscle evoked by stimulation of the mesencephalic locomotor region (MLR). Motoneuron discharge patterns, firing rates, and the ...

journal_title：Journal of neurophysiology

authors： Tansey KE,Botterman BR

更新日期：1996-01-01 00:00:00

abstract：:1. High-voltage-activated Ca2+ currents [ICa(HVA)] were studied in immunolabeled mouse retinal ganglion neurons (RGNs) to elucidate channel-specific components and their developmental changes in vitro. 2. Neurons were dissociated at postnatal day 5. RGNs were selected for electrophysiological measurements by vital lab...

journal_title：Journal of neurophysiology

authors： Rothe T,Grantyn R

更新日期：1994-11-01 00:00:00

abstract：:1. GABAergic mechanisms in the midbrain periaqueductal gray (PAG) have been proposed to control the activity of descending antinociceptive systems and defensive behavior. Here, the effect of neuronal disinhibition by gamma-aminobutyric acid (GABAA) receptor blockade at midbrain sites on spinal neuronal responses to no...

journal_title：Journal of neurophysiology

authors： Sandkühler J,Willmann E,Fu QG

更新日期：1991-01-01 00:00:00

abstract：:A popular theory is that the cerebellum functions as a timer for clocking motor events (e.g., initiation, termination). Consistent with this idea, cerebellar patients have been reported to show greater deficits during hand movements that repeatedly start and stop (i.e., discontinuous movements) compared with continuou...

journal_title：Journal of neurophysiology

authors： Bo J,Block HJ,Clark JE,Bastian AJ

更新日期：2008-11-01 00:00:00

abstract：:Visual input provides vital information for helping us modify our walking pattern. For example, artificial optic flow can drive changes in step length during locomotion and may also be useful for augmenting locomotor training for individuals with gait asymmetries. Here we asked whether optic flow could modify the acqu...

journal_title：Journal of neurophysiology

authors： Finley JM,Statton MA,Bastian AJ

更新日期：2014-03-01 00:00:00

abstract：:We have investigated whether neurons in superficial laminae of the spinal dorsal horn respond to intracutaneous (ic) delivery of histamine and other irritant chemicals, and thus might be involved in signaling sensations of itch or chemogenic pain. Single-unit recordings were made from superficial lumbar dorsal horn ne...

journal_title：Journal of neurophysiology

authors： Jinks SL,Carstens E

更新日期：2000-08-01 00:00:00

abstract：:1. The purpose of this study is to analyze the kinematics of stepping from the point of view of limb control by attempting to dissociate the various neuronal and mechanical factors that shape actual movements observed experimentally. The cat hindlimb, like the primate arm, is a multijointed mechanical system with redu...

journal_title：Journal of neurophysiology

authors： Shen L,Poppele RE

更新日期：1995-12-01 00:00:00

abstract：:The role of metabotropic glutamate receptors (mGluRs) and adenosine receptors in hypoxia-induced suppression of excitatory synaptic input to interneurons residing at the granule cell-hilus border in the dentate gyrus was investigated with the use of whole cell electrophysiological recording techniques in thin (250 mic...

journal_title：Journal of neurophysiology

authors： Doherty J,Dingledine R

更新日期：1997-01-01 00:00:00

abstract：:We have characterized selectivity and sparseness in anterior inferotemporal cortex, using a large data set. Responses were collected from 674 monkey inferotemporal cells, each stimulated by 806 object photographs. This 806 × 674 matrix was examined in two ways: columnwise, looking at responses of a single neuron to al...

journal_title：Journal of neurophysiology

authors： Lehky SR,Kiani R,Esteky H,Tanaka K

更新日期：2011-09-01 00:00:00

abstract：:Activity-dependent developmental maturation of the neocortical network is thought to involve the stabilization and potentiation of immature synapses. In particular, N-methyl-d-aspartate (NMDA) receptor-dependent long-term plasticity that is expressed presynaptically appears to be crucial for the selection of functiona...

journal_title：Journal of neurophysiology

authors： Walz C,Jüngling K,Lessmann V,Gottmann K

更新日期：2006-12-01 00:00:00

abstract：:Accurate temporal coding of low-frequency tones by spikes that are locked to a particular phase of the sine wave (phase-locking), occurs among certain groups of neurons at various processing levels in the brain. Phase-locked responses have previously been studied in the inferior colliculus and neocortex of the guinea ...

journal_title：Journal of neurophysiology

authors： Wallace MN,Anderson LA,Palmer AR

更新日期：2007-10-01 00:00:00

abstract：:We measured synaptic responses to complex stimulus trains in the calyx of Held and used the data to test how well several vesicle-release models could capture the observed dynamics. We tested stimulation protocols consisting of Poisson-distributed activity with periodically changing mean frequencies, trains with const...

journal_title：Journal of neurophysiology

authors： Hermann J,Grothe B,Klug A

更新日期：2009-01-01 00:00:00

abstract：:Previous studies have shown that daily, moderate-level sound exposure, or conditioning, can reduce injury from a subsequent high-level noise exposure. We tested the hypothesis that this conditioning produces an increased activity in the olivocochlear efferent reflex, a reflex known to provide protection to the cochlea...

journal_title：Journal of neurophysiology

authors： Brown MC,Kujawa SG,Liberman MC

更新日期：1998-06-01 00:00:00

abstract：:Dopamine (DA) neurons and GABA neurons of the substantia nigra (SN) promote distinct functions in the control of movement and have different firing properties and action potential (AP) waveforms. APs recorded from DA and GABA neurons differed in amplitude, maximal rate of rise, and duration. In addition, the threshold...

journal_title：Journal of neurophysiology

authors： Seutin V,Engel D

更新日期：2010-06-01 00:00:00

abstract：:1. The physiology and pharmacology of the connections made by stress-sensitive campaniform sensilla on the proximal dorsal tibia of a locust hind leg with a fast extensor tibiae motor neuron (FETi) have been examined. 2. Mechanical stimulation of a campaniform sensillum on the anterior surface of the tibia elicited bu...

journal_title：Journal of neurophysiology

authors： Parker D,Newland PL

更新日期：1995-02-01 00:00:00

abstract：:The intrinsic properties of tonically firing neurons in the cochlear nucleus contribute to representing average sound intensity by favoring synaptic integration across auditory nerve inputs, reducing phase locking to fine temporal acoustic structure and enhancing envelope locking. To determine whether tonically firing...

journal_title：Journal of neurophysiology

authors： Kreeger LJ,Arshed A,MacLeod KM

更新日期：2012-11-01 00:00:00

abstract：:1. The retinotopic organization of retinal inputs from the lateral eye of Limulus to the optic ganglia of the brain was determined from microelectrode recordings of nerve impulses. 2. The central connections of the natural subunits of the lateral optic nerve were determined using cobalt impregnation of cut axons. 3. C...

journal_title：Journal of neurophysiology

authors： Chamberlain SC,Barlow RB Jr

更新日期：1982-08-01 00:00:00