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Sudden vs gradual onset of chronic fatigue syndrome differentiates individuals on cognitive and psychiatric measures.

Abstract：

:To examine the influence of mode of illness onset on psychiatric status and neuropsychological performance, 36 patients with CFS were divided into two groups: sudden vs gradual onset of symptoms. These two CFS subgroups were compared to each other and to sedentary healthy controls on standardized neuropsychological tests of attention/concentration, information processing efficiency, memory, and higher cortical functions. In addition, the distribution of comorbid Axis I psychiatric disease between the two CFS groups was examined. The rate of concurrent psychiatric disease was significantly greater in the CFS-gradual group relative to the CFS-sudden group. While both CFS groups showed a significant reduction in information processing ability relative to controls, impairment in memory was more severe in the CFS-sudden group. Because of the significant heterogeneity of the CFS population, the need for subgroup analysis is discussed.

journal_name

J Psychiatr Res

journal_title

Journal of psychiatric research

authors

DeLuca J,Johnson SK,Ellis SP,Natelson BH

doi

10.1016/s0022-3956(96)00052-0

subject

Has Abstract

pub_date

1997-01-01 00:00:00

pages

83-90

issue

1

eissn

0022-3956

issn

1879-1379

pii

S0022395696000520

journal_volume

31

pub_type

杂志文章

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