Abstract：
:The influence of caloric load and nutrient composition on small intestinal satiety was investigated in six dogs with chronic esophageal fistulas. Dogs received small bowel infusion of a mixed nutrient liquid meal, a fat, carbohydrate, and a protein solution over two hours. Each infusion was given over a range of caloric densities which represented between 0 to 20% of the total 24 h caloric requirement for each animal. Satiety was measured by sham feeding at the end of the infusion. Infusion of 0.25 cal/ml (equivalent to 5% of the 24 h caloric requirement) of a liquid mixed nutrient meal (Isocal) significantly suppressed sham feeding (volume sham fed: control 265 +/- 28 ml/min; Isocal 0.25 cal/ml 218 +/- 52 ml/min, p < 0.05). Oleate and dextrose polymer also significantly reduced sham feeding at a caloric concentration of 0.25 cal/ml (volume sham fed: control 265 +/- 28 ml/min; oleate 112 +/- 28 ml/min; oleate 112 +/- 9 ml/min; dextrose polymer 190 +/- 11 ml/min), whereas peptone did not significantly suppress sham feeding until a solution with 0.5 cal/ml was given. These studies demonstrate that caloric load of intestinal nutrients must reach a threshold to produce satiety in sham feeding dogs. The threshold caloric load is different for the three nutrient groups, with fats requiring the lowest caloric load to produce satiety. These provide insight into the mechanisms by which small intestinal signals might contribute to regulation of the inter-meal interval.
journal_name
Physiol Behavjournal_title
Physiology & behaviorauthors
Geoghegan JG,Cheng CA,Lawson C,Pappas TNdoi
10.1016/s0031-9384(97)00107-8subject
Has Abstractpub_date
1997-07-01 00:00:00pages
39-42issue
1eissn
0031-9384issn
1873-507Xpii
S0031-9384(97)00107-8journal_volume
62pub_type
杂志文章abstract：:KINSEY, S. G., BAILEY, M. T., SHERIDAN, J. F., PADGETT, D. A. The inflammatory response to social defeat is increased in older mice. PHYSIOL BEHAV 91(0) 000-000, 2007. Previous research indicates that repeated social defeat of mice causes increased lymphocyte trafficking to the spleen, elevated proinflammatory cytokin...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2007.11.003
更新日期：2008-02-27 00:00:00
abstract：:Previous studies have reported binge-type consumption of solid vegetable shortening in non-food deprived rats maintained on schedules of limited shortening access. The current study determined if limited access would promote binge-type consumption of sucrose solutions. Adult male rats (6 groups, n = 10 each) were prov...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2007.05.002
更新日期：2007-11-23 00:00:00
abstract：:The sensory properties of foods and beverages are primary determinants of food choice. Some flavor components have an inherent hedonic valence that influences ingestive behavior. However, these hedonic impressions may be modified and others newly formed through their association with the post-ingestive consequences of...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2011.10.028
更新日期：2012-11-05 00:00:00
abstract：:Four groups of pigeons each were trained to perform four visual-discrimination tasks of varying difficulty. Two groups received the training binocularly and the other two monocularly. Two types of stimulus displays were used. In one display the two pecking keys were mounted in a horizontal arrangement, whereas, in the...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(84)90204-x
更新日期：1984-05-01 00:00:00
abstract：:The human body associates sensory cues with metabolic consequences. Exposure to sweet-tasting sugars - even in the absence of ingestion - triggers physiological responses that are associated with carbohydrate digestion, absorption and metabolism. These responses include the release of insulin and incretin hormones, wh...
journal_title：Physiology & behavior
pub_type： 杂志文章,评审
doi：10.1016/j.physbeh.2017.09.016
更新日期：2017-12-01 00:00:00
abstract：:The relationship between consumption of a confectionery snack after an overnight fast and cognitive function was examined using a variety of cognitive tasks, including spatial memory, verbal memory, attention, visual perception and short-term memory, in a sample of 21 boys, ages 9-12 years. Performance on the vigilanc...
journal_title：Physiology & behavior
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0031-9384(02)00882-x
更新日期：2002-11-01 00:00:00
abstract：:The effect of breakfast and breakfast omission on daily food intake in normal and overweight participants was investigated. 37 participants were recruited for this experimental study and assigned to one of four groups on the basis of their body mass index (BMI) (normal weight BMI <25 kg/m(2) or overweight/obese BMI >2...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2014.05.015
更新日期：2014-06-22 00:00:00
abstract：:The allostatic load model has been used to quantify the physiological costs of the body's response to repeated stressful demands and may provide a useful, integrative perspective on the various correlates of late-life depressive symptoms. We interviewed 125 Rochester, NY adults, ranging in age from 67 to 94 years. We ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2013.10.014
更新日期：2014-01-17 00:00:00
abstract：BACKGROUND:Appetite regulating properties of foods are usually investigated under laboratory conditions, whereas in real life, foods are consumed under at home conditions. The objective of this study was to compare the acute effects of breakfasts when tested in a laboratory condition and in an at home condition. Appeti...
journal_title：Physiology & behavior
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.physbeh.2018.06.024
更新日期：2018-10-01 00:00:00
abstract：:Each of three monkeys was operantly conditioned to slow its heart, to exercise (lift weights) and to attenuate the tachycardia of exercise by combining these two skills. Each was further tested during beta-adrenergic blockade (atenolol), combined alpha-adrenergic blockade (prazosin) and beta-adrenergic blockade, or ch...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(91)90058-v
更新日期：1991-02-01 00:00:00
abstract：BACKGROUND:Hydrogen sulfide (H2S) is the third gasotransmitter recently discovered after nitric oxide (NO) and carbon monoxide. Both NO and H2S are involved in multiple physiological functions. Whereas NO has been shown to vary with psychological stress, the influence of stress on H2S and the relationship between H2S a...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2017.05.023
更新日期：2017-10-01 00:00:00
abstract：:Calorie restriction (CR) has been promoted to increase longevity. Previous studies have indicated that CR can negatively affect mood and therefore the effect of CR on mood and quality of life (QOL) becomes crucial when considering the feasibility of CR in humans. We conducted a three month clinical trial on CR (reduct...
journal_title：Physiology & behavior
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.physbeh.2011.07.007
更新日期：2011-10-24 00:00:00
abstract：:These studies describe diurnal rhythm changes in female rats during gestation and lactation. In Experiment I, we measured the diurnal temperature rhythm (DTR) of 20 females through gestation, lactation and the post-lactational period and found that rhythm amplitude decreased during gestation and increased during lacta...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(88)90180-1
更新日期：1988-01-01 00:00:00
abstract：:Young pigs, which are useful experimental animals for biomedical research, were prepared with lateral intracerebroventricular (ICV) cannulae and housed individually in cages fitted with operant panels, with food and water ad lib. ICV injection of 200 micrograms of dynorphin A 1-17 or 1-13 resulted in a significant mea...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(90)90233-t
更新日期：1990-12-01 00:00:00
abstract：BACKGROUND:Studies evaluating the efficacy of anti-inflammatory treatment strategies for major depressive disorder (MDD) commonly include participants who do not demonstrate elevated concentrations of baseline inflammatory mediators, or simply fail to assess baseline inflammation. This may result in an underestimation ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2019.05.006
更新日期：2019-08-01 00:00:00
abstract：:To test the hypothesis that testosterone (T) sexually differentiates gonadotropin secretion and sexual behavior by inducing synthesis of messenger RNA (mRNA), newborn female rats received intrahypothalamic infusions of saline or cordycepin, an adenosine analogue that preferentially inhibits synthesis of polyadenylated...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(87)90264-2
更新日期：1987-01-01 00:00:00
abstract：:The influence of endogenous opioid peptides (EOPs) on plasma luteinizing hormone (LH) levels in subordinate female highveld mole-rats (Cryptomys hottentotus pretoriae) was investigated to elucidate the physiological mechanisms responsible for inhibiting their gonadotropin-releasing hormone (GnRH) and/or LH release. Th...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2006.02.005
更新日期：2006-05-30 00:00:00
abstract：:Micrencephalic offspring produced by gestational treatment with the antimitotic compound/methylazoxymethanol acetate (MAM) are remarkable for substantial preservation of function concurrent with severe neural stunting. Altered behaviors in these micrencephalics, including light shyness and response perseveration, are ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(95)00154-b
更新日期：1995-11-01 00:00:00
abstract：:Sleep, waking, and EEG power spectra were investigated in rats with spinal 5,6-dihydroxytryptamine (5,6-DHT) lesions, following 20 mg/kg zimeldine or vehicle IP injections. 5,6-DHT selectively lesioned the descending serotonergic pathways. Lesion alone did not change sleep and waking stages compared to baseline, excep...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(94)00370-k
更新日期：1995-05-01 00:00:00
abstract：:Subjects consumed soup (beef consomme) preloads of a fixed size containing different concentrations of monosodium L-glutamate (MSG). Effects on appetite following these preloads, and when no soup was consumed, were assessed in 3 studies. The soups supplemented with MSG were rated as more "pleasant," more "savoury" and...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(90)90230-2
更新日期：1990-12-01 00:00:00
abstract：:We evaluated how two diets with different lipid levels (4% vs. 10%) influenced nutrient expenditure in juvenile walleye Stizostedion vitreum subjected to starvation, prolonged swimming, and predator presence. We also determined how exercise and predator presence influenced stress indicators such as blood plasma cortis...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(03)00124-0
更新日期：2003-09-01 00:00:00
abstract：:Neurons synthesizing corticotrophin-releasing hormone (CRH) in the paraventricular nucleus of the hypothalamus (PVN) are activated during acute stress and act via the hypothalamic-pituitary-adrenal (HPA) axis to increase systemic levels of corticosterone (CORT). Recent data indicates that CRH neurons in the PVN are in...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2017.03.038
更新日期：2017-07-01 00:00:00
abstract：:A protocol suited to the investigations of odor-taste interactions in a functional magnetic resonance imaging (fMRI) scanner is described and results that confirm the validity of that protocol are presented. Stimuli were dissolved in water and presented to the mouth of the participant through plastic syringes and plas...
journal_title：Physiology & behavior
pub_type： 临床试验,杂志文章
doi：10.1016/j.physbeh.2003.12.018
更新日期：2004-05-01 00:00:00
abstract：:The present experiment investigated the effects of exposure to inescapable shocks (IS) on subsequent behavior in an elevated plus-maze and on shuttlebox-escape performance in male and female rats. In the elevated plus-maze, exposure to IS resulted in suppression of "total number of arm entries" and "rearings" in males...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(90)90302-k
更新日期：1990-10-01 00:00:00
abstract：:Sleep/wake expression in mice varies predictably with circadian phase. Such circadian rhythms are known to depend on intact suprachiasmatic nuclei (SCN) in the hypothalamus, but the mechanism by which SCN activity modulates sleep/wake expression is unknown. This paper examines the possibility that circadian patterns o...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(88)90375-7
更新日期：1988-01-01 00:00:00
abstract：:Previous research has demonstrated that rapid eye movement (REM), or paradoxical, sleep deprivation can interfere with the retention of certain types of learning tasks, particularly spatial learning. The present study investigated the effects of 6 h of REM sleep deprivation on the retention and extinction of both cued...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2004.11.011
更新日期：2005-03-16 00:00:00
abstract：:It has been recognized for some time that a number of different neuropeptides exert powerful effects on food intake. During the last few years, the neurocircuitry within which these peptides operate has also begun to be elucidated. Peptidergic feeding-regulatory neurones are found both in the hypothalamus and the brai...
journal_title：Physiology & behavior
pub_type： 杂志文章,评审
doi：10.1016/s0031-9384(01)00611-4
更新日期：2001-11-01 00:00:00
abstract：:The role of the endocannabinoid system in vomiting has been previously studied using several animal species. These investigations have clearly demonstrated an anti-emetic role for the eCB, anandamide, in these animal models; however, research concerning the role of 2-arhachidonoylglycerol (2AG) has been less clear. Th...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2013.08.015
更新日期：2013-08-15 00:00:00
abstract：:This study compared subjective effort perception with objective physiological measures during high-intensive intermittent exercise performed in normoxia, moderate hypoxia (FiO2: 16.5%) and severe hypoxia (FiO2: 13.5%). Sixteen physically active subjects performed an equal training session on three different days. Trai...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2016.04.035
更新日期：2016-09-01 00:00:00
abstract：:Twenty-four-hour recordings of electrophysiological correlates of the sleep-waking cycle in the rat were performed during different stages of cuff pedestal treatment. It was found that rats adapted to live on pedestals with the cuff raised displayed undisturbed patterns of sleep and wakefulness. Lowering the cuff for ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(84)90283-x
更新日期：1984-06-01 00:00:00
