Raising the curtain on cancer. Is the puzzle finally becoming clear?

abstract：BACKGROUND:Irritable bowel syndrome with constipation (IBS-C) and chronic idiopathic constipation (CIC) are common functional bowel disorders. Patients with IBS-C or CIC often present with ≥ 1 comorbidity that coincides with either of these conditions. These comorbidities may make underappreciated contributions to the ...

journal_title：Postgraduate medicine

authors： Nellesen D,Chawla A,Oh DL,Weissman T,Lavins BJ,Murray CW

更新日期：2013-03-01 00:00:00

abstract：:With increased survival of increasing numbers of cancer patients as a result of therapy, the consequences, early and late, of the therapies must be realized. It is the treating physician's duty to preserve as much reproductive potential as possible for patients, consistent with adequate care. With radiotherapy this me...

journal_title：Postgraduate medicine

authors： Maguire LC

更新日期：1979-05-01 00:00:00

abstract：:In public whirlpools, low disinfectant levels and inadequate monitoring are clearly a public health concern. Implementing guidelines published by the Centers for Disease Control seems to be the most reasonable approach to preventing dermatitis in persons who use these facilities. Physicians should be on the alert for ...

journal_title：Postgraduate medicine

authors： Breitenbach RA

更新日期：1991-09-01 00:00:00

abstract：:Patients with dyslipidemia receive a cardiovascular benefit from lowering low-density lipoprotein cholesterol (LDL-C). Atorvastatin is currently one of the most effective approved medications for lowering LDL-C, and has been shown to significantly reduce cardiovascular risk in many patient groups. However, even with s...

journal_title：Postgraduate medicine

authors： McKenney JM

更新日期：2012-01-01 00:00:00

abstract：:Many aspects of Kawasaki syndrome remain a mystery. The cause of the disease has eluded researchers, and its pathophysiology is a subject of much debate. However, the diagnostic features have been identified: A significant fever for at least 5 days, bilateral nonexudative conjunctivitis, erythema of the palms and sole...

journal_title：Postgraduate medicine

authors： Applegate BL

更新日期：1995-02-01 00:00:00

abstract：:Although low-dose oral corticosteroid therapy cannot be considered remittive, it has earned a place in the therapeutic armamentarium for rheumatoid arthritis. Major clinical trials of a group using corticosteroid compared with a control group have not been done since the 1950s. One of these three large trials showed s...

journal_title：Postgraduate medicine

authors： Iannuzzi LP

更新日期：1987-10-01 00:00:00

abstract：:Carotid endarterectomy for carotid artery stenosis is valuable for some patients, but not all. Results of clinical trials in symptomatic and asymptomatic patients provide guidance on use of this common vascular procedure. The authors of this article describe the controversies and concerns with the procedure and give t...

journal_title：Postgraduate medicine

authors： Ingall TJ,Dodick DW,Zimmerman RS

更新日期：2000-05-15 00:00:00

abstract：:This case report describes prolongation of a patient's prothrombin time and partial thromboplastin time possibly due to coadministration of warfarin and an overdose of an acetaminophen-propoxyphene combination analgesic. Patients receive warfarin for many indications, and concomitant use of an analgesic agent is commo...

journal_title：Postgraduate medicine

authors： Justice JL,Kline SS

更新日期：1988-04-01 00:00:00

abstract：:Both recreational and elite athletes often sustain musculoskeletal injuries. Common problems--muscle cramps, burners (or stingers), and ankle and shoulder injuries--can be managed effectively with certain basic techniques. Initial measures are particularly important in facilitating the injured athlete's rapid return t...

journal_title：Postgraduate medicine

authors： Sellers RG

更新日期：1992-08-03 00:00:00

abstract：:Biochemical monitoring is generally advised for drugs that are potentially toxic, have a narrow therapeutic range, or are prescribed for life-threatening disease. Monitoring should not be attempted until the serum concentration reaches a plateau, or steady state, and sampling must be timed carefully. Besides incorrect...

journal_title：Postgraduate medicine

authors： Burke MD

更新日期：1981-07-01 00:00:00

abstract：:Many men experience sexual function disorders, the most common of which are PE and ED. However, they may hesitate to seek treatment because of the perceived embarrassment associated with discussing their symptoms with a physician. The introduction of PDE-5 inhibitors for the treatment of ED has resulted in increased a...

journal_title：Postgraduate medicine

authors： Miner M,Hellstrom WJ

更新日期：2008-04-01 00:00:00

abstract：:Gallstones are very common, but at least two thirds of detected stones are asymptomatic and a large number undoubtedly go undetected. The presence of symptoms or complications is the indication for surgery. It is important to accurately identify which symptoms are caused by gallstones, because removing the gallbladder...

journal_title：Postgraduate medicine

authors： Egbert AM

更新日期：1991-10-01 00:00:00

abstract：:Even modest alcohol ingestion can increase the risk of steatosis, and long-term, excessive consumption can lead to alcoholic hepatitis and eventually cirrhosis. Most patients with clinically significant alcoholic liver disease have histologic findings typical of all three conditions. The only clearly beneficial treatm...

journal_title：Postgraduate medicine

authors： Hill DB,Kugelmas M

更新日期：1998-04-01 00:00:00

abstract：:The Editor welcomes readers' comments, and selected letters are published each month. Letters must be signed and should be sent to Editor's Mail at the address shown. The journal reserves the right to condense letters if necessary for space. ...

journal_title：Postgraduate medicine

authors： Butler T,Cunha BA

更新日期：1982-03-01 00:00:00

abstract：:The Food and Drug Administration's approval of the excimer laser in 1995 heralded the age of laser refractive surgery in the United States. Since then, other advances in refractive surgery have spurred great public interest in and enthusiasm for these procedures. In this article, the authors review the major types of ...

journal_title：Postgraduate medicine

authors： Chaudhry IM,Conti ER,Steinert RF

更新日期：1999-09-01 00:00:00

abstract：:Phencyclidine (PCP) is a dissociative anesthetic whose abuse is a growing problem. Historically, its effects have been considered remarkably like those of the schizophrenic state, but in vitro and in vivo neuropharmacologic data are somewhat inconsistent with the dopaminergic hypothesis of schizophrenia. The physiolog...

journal_title：Postgraduate medicine

authors： Beede MS

更新日期：1980-11-01 00:00:00

abstract：:Inhaled corticosteroids (ICSs) belong to the armament for treatment of chronic obstructive pulmonary disease (COPD) and as such, they are widely used in real life. This is a narrative review on evidence-based papers published in the English language listed in Medline between 1990 and March 2016 discussing ICS applicat...

journal_title：Postgraduate medicine

authors： Andreeva-Gateva PA,Stamenova E,Gatev T

更新日期：2016-06-01 00:00:00

abstract：:Several risks can be posed by travel, even when the stay is not protracted nor the destination exotic. Air travelers should consider the potential problems associated with decreased cabin pressure, hypoxia, and circadian dysrhythmia, problems that can contraindicate flying for some. Motion sickness can affect those tr...

journal_title：Postgraduate medicine

authors： Lange WR,Kreider SD

更新日期：1983-04-01 00:00:00

abstract：OBJECTIVES:We aimed to determine the prevalence of chronic diseases and unhealthy lifestyle behaviors of Turkish doctors as compared with the general population and the frequency of compliance with preventive clinical practices among doctors. METHODS:This was an observational, prospective cohort study that enrolled gr...

journal_title：Postgraduate medicine

authors： Unal S,Tanriover MD,Ascioglu S,Demirkazik A,Ertenli I,Eskioglu E,Guler K,Kiraz S,Ozbakkaloglu M,Ozer B,Tukek T,Akyar S,Erdem Y

更新日期：2017-04-01 00:00:00

abstract：:Acute cardiac events involving coronary symptoms, elevated enzyme levels, and electrocardiographic changes without the development of Q waves often result in higher rates of reinfarction and unstable angina than do more severe myocardial infarctions. The incidence of these non-Q wave events is on the rise, possibly be...

journal_title：Postgraduate medicine

authors： Tamberella MR 3rd,Warner JG Jr

更新日期：2000-02-01 00:00:00

abstract：:Normalization of serum lipid levels should be initiated as soon as possible in patients with myocardial, cerebrovascular, or peripheral vascular disease. Clinical trials indicate that coronary artery disease and overall mortality rates can be reduced and atherosclerosis stabilized or reversed by lipid-lowering therapy...

journal_title：Postgraduate medicine

authors： Blankenhorn DH,Hodis HN

更新日期：1991-01-01 00:00:00

abstract：:Hypertension in diabetic patients must be treated aggressively if patients are to benefit from reduced risk of morbidity and mortality. Diabetes itself must be diagnosed promptly, particularly in at-risk patients, so appropriate lifestyle modifications can be made at the earliest opportunity. Although this may reduce ...

journal_title：Postgraduate medicine

authors： Sowers JR,Williams M,Epstein M,Bakris G

更新日期：2000-04-01 00:00:00

abstract：:Self-monitoring of blood glucose (SMBG) levels provides important information regarding glycemic control for patients with diabetes, and is recommended by European and American diabetes organizations as an essential adjunct to periodic glycated hemoglobin (HbA1c) level monitoring. The benefits of SMBG in improving gly...

journal_title：Postgraduate medicine

authors： Blevins T

更新日期：2013-05-01 00:00:00

abstract：:Whether preparticipation sports examinations are necessary and what they should include are matters of debate, especially in the young because of the low yield of new medical diagnoses. The goal of the examining physician is to determine whether the athlete is mentally, developmentally, and physically capable of safel...

journal_title：Postgraduate medicine

authors： Bratton RL,Agerter DC

更新日期：1995-08-01 00:00:00

abstract：:The chronic pain syndrome differs from chronic pain. The syndrome is a psychologic stress state that can produce physical-type illness, often with musculoskeletal manifestations. It tends to strike the "worried well," by nature hysterical, depressed, hypochondriacal, and dependent. Standard medical, surgical, and psyc...

journal_title：Postgraduate medicine

authors： Florence DW

更新日期：1981-11-01 00:00:00

abstract：:Remittent isolated palsy of peripheral or of upper cranial nerves in patients with diabetes mellitus is well documented, but paralysis of a lower cranial nerve or an isolated branch of any cranial nerve has not been previously reported. In the case described, temporary paralysis of the left recurrent laryngeal nerve c...

journal_title：Postgraduate medicine

authors： Kabadi UM

更新日期：1988-09-15 00:00:00

abstract：:Many drugs with which to treat reversible obstructive airway disease are available. Beta-adrenergic aerosols are the first line of defense; these are followed, when necessary, by either timed-release theophylline or oral beta-adrenergics. Often, a combination of these drugs must be used to achieve effective relief of ...

journal_title：Postgraduate medicine

authors： O'Loughlin JM

更新日期：1987-07-01 00:00:00

abstract：:While there is evidence for cardiac arrhythmias associated with macrolide and fluoroquinolone antibiotics, there is still debate among health care providers as to whether this risk of arrhythmia is overstated. A joint panel of the US Food and Drug Administration suggested that macrolide and fluoroquinolone labels need...

journal_title：Postgraduate medicine

authors： Cornett E,Novitch MB,Kaye AD,Pann CA,Bangalore HS,Allred G,Bral M,Jhita PK,Kaye AM

更新日期：2017-09-01 00:00:00

abstract：:Pulmonary artery hypertension (PAH) refers to several subgroups of disease in which the mean pulmonary artery pressure (mPAP) is elevated to more than 25 mm Hg, pulmonary artery wedge pressure (PAWP) ≤ 15 mmHg, and an elevated pulmonary vascular resistance (PVR) > 3 Wood units as confirmed by right heart catheterizati...

journal_title：Postgraduate medicine

authors： Velayati A,Valerio MG,Shen M,Tariq S,Lanier GM,Aronow WS

更新日期：2016-06-01 00:00:00

abstract：:Platelets play a key role in the initiation of hemostatic mechanisms during vascular injury. When contemplating prescription of antiplatelet agents (APAs) for patients as primary prevention for cardiovascular events, the physician should carefully weigh the potential benefits of cardiovascular risk reduction with the ...

journal_title：Postgraduate medicine

authors： Acharji S,Lakshmanadoss U,Rudzinski W,Stapleton DD,Kaluski E

更新日期：2013-09-01 00:00:00