Treating serum lipid abnormalities in high-priority patients.

Abstract:

:Normalization of serum lipid levels should be initiated as soon as possible in patients with myocardial, cerebrovascular, or peripheral vascular disease. Clinical trials indicate that coronary artery disease and overall mortality rates can be reduced and atherosclerosis stabilized or reversed by lipid-lowering therapy. Treatment should lower low-density lipoprotein cholesterol levels to 130 mg/dL or less and total triglyceride levels to 150 mg/dL or less and increase high-density lipoprotein cholesterol levels to at least 52 mg/dL in men and 66 mg/dL in women. Nonlipid coronary risk factors should be eliminated when possible. Lipid-lowering therapy may consist of dietary modification and drug treatment with colestipol hydrochloride (Colestid), cholestyramine (Cholybar, Questran), lovastatin (Mevacor), gemfibrozil (Lopid), and nicotinic acid (Nicolar).

journal_name

Postgrad Med

journal_title

Postgraduate medicine

authors

Blankenhorn DH,Hodis HN

doi

10.1080/00325481.1991.11700787

subject

Has Abstract

pub_date

1991-01-01 00:00:00

pages

81-2, 87-90, 93-6

issue

1

eissn

0032-5481

issn

1941-9260

journal_volume

89

pub_type

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