Principles of therapeutic drug monitoring.

abstract：:Even healthy persons may experience some form of altitude illness when they hike or ski in high mountains. Therefore, it is imperative that those with compromised cardiac or pulmonary function take extra precautions by allowing time for ascent, by recognizing and accepting their limitations, and by descending promptly...

journal_title：Postgraduate medicine

authors： Houston CS

更新日期：1990-07-01 00:00:00

abstract：:The end point in peptic ulcer disease is a crater in the mucosa. The cause of gastric ulcers seems to be the breakdown of defensive factors, which then allows damage from endogenous and/or exogenous aggressive factors. Aggressive factors are more important in duodenal ulcer formation. Treatment options discussed herei...

journal_title：Postgraduate medicine

authors： Ziller SA 3rd,Netchvolodoff CV

更新日期：1993-03-01 00:00:00

abstract：:A 65-year-old woman presented to the hospital with weight loss and diarrhea. A diagnosis of thyroid storm was established by the presence of fever, lethargy, tachycardia, heart failure (HF), and abnormal thyroid function tests. An acute coronary syndrome (ACS) was suspected because of anteroseptal ST-segment elevation...

journal_title：Postgraduate medicine

authors： Radhakrishnan A,Granato JE

更新日期：2009-05-01 00:00:00

abstract：:Human sexuality is a lifelong process with biologic, psychosocial, and moral consequences. During adolescence, coping with sexual feelings and controlling sexual drive become urgent tasks that are made more difficult by today's society. Recent studies document a dramatic increase in the frequency of sexual activity am...

journal_title：Postgraduate medicine

authors： Shen JT

更新日期：1982-04-01 00:00:00

abstract：:Patients with colon cancer involving regional lymph nodes (stage C disease) have a 5-year survival rate of only 30% to 40%, and the majority die of recurrent disease. Recent trials have shown increased survival rates with postoperative use of fluorouracil plus levamisole. The authors discuss these findings and the imp...

journal_title：Postgraduate medicine

authors： Treat J,Joseph RR

更新日期：1990-10-01 00:00:00

abstract：:GRATEFUL MED is a computer program for searching the medical literature, designed with the novice in mind. It contains an extensive list of medical subject headings, so the user does not have to page through an index of key words before starting the search. Because of its efficiency and ease of operation, the program ...

journal_title：Postgraduate medicine

authors： Schell CL,Rathe RJ

更新日期：1988-01-01 00:00:00

abstract：:Preview Although no one theory on aging explains satisfactorily why or how this process occurs, we know that aging causes physiologic changes and a progressive decline of functional organ reserve. The implications of these changes are increasingly important as the elderly segment of the population grows. In this artic...

journal_title：Postgraduate medicine

authors： Troncale JA

更新日期：1996-05-01 00:00:00

abstract：:In this review, we focus on current trends in the management of male lower urinary tract symptoms (LUTS), defined here as LUTS, namely, storage, voiding, and post-micturition symptoms presumed secondary to benign prostatic hyperplasia (BPH), and discuss possible novel approaches toward better care. According to result...

journal_title：Postgraduate medicine

authors： Roehrborn CG,Miner MM,Sadovsky R

更新日期：2018-06-01 00:00:00

abstract：:Preview Just when it appeared that diuretics were becoming obsolete in the attack against hypertension, they have come charging back to the fore. This is especially true in treatment of systolic hypertension in the elderly. The perspective on diuretics and their recommendations for administration have changed recently...

journal_title：Postgraduate medicine

authors： Cushman WC

更新日期：1993-08-01 00:00:00

abstract：:Careful attention to the practical aspects of oral anticoagulant therapy can improve patient compliance and lessen the risk of bleeding complications. A variety of risk factors for bleeding associated with oral anticoagulant therapy have been defined and should be assessed before initiating therapy. Recent investigati...

journal_title：Postgraduate medicine

authors： Brigden ML

更新日期：1996-06-01 00:00:00

abstract：:Primary adrenal insufficiency due to tumor involvement is very rare. We herein report a case of adrenal insufficiency caused by cancer metastasis to a remaining single adrenal gland in a renal cell carcinoma patient who had undergone radical nephrectomy including removal of the right adrenal gland. The patient present...

journal_title：Postgraduate medicine

authors： Lee MW,Lee HJ

更新日期：2020-04-01 00:00:00

abstract：:Fluoroquinolone-resistant variants of pandemic clones Spain(23F)-1, Spain(6B)-2, Spain(9V)-3, and Spain(14)-5 have been seen in various regions of the United States and the world, leading to the speculation that fluoroquinolone resistance among US Streptococcus pneumoniae may increase because of clonal spread. Using l...

journal_title：Postgraduate medicine

authors： Davies TA,Yee YC,Goldschmidt R,Sahm DF,Evangelista AT

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVE:To evaluate the pharmacokinetics of lisdexamfetamine dimesylate (LDX), a long-acting prodrug stimulant, and mixed amphetamine salts extended-release (MAS XR), alone or with omeprazole, a proton pump inhibitor (PPI). METHODS:This open-label, randomized, 4-period crossover study enrolled healthy adults (18-45 ...

journal_title：Postgraduate medicine

authors： Haffey MB,Buckwalter M,Zhang P,Homolka R,Martin P,Lasseter KC,Ermer JC

更新日期：2009-09-01 00:00:00

abstract：:The practitioner plays an important role in providing guidance for exercise. Physical activity is one component of a life-style aimed at enhancing the health of the individual. When entered into with appropriate understanding and with reasonable expectations and goals, exercise can also be a major source of enjoyment....

journal_title：Postgraduate medicine

authors： Smith LK

更新日期：1988-01-01 00:00:00

abstract：:Drug-induced illness is common in any clinical practice. The consequences of failure or delay in diagnosis--persistent or recurring illness, unnecessary diagnostic evaluation, inappropriate treatment, and future jeopardy from the drug--can be avoided by early recognition. Using descriptions of cases from his practice,...

journal_title：Postgraduate medicine

authors： Savett LA

更新日期：1980-01-01 00:00:00

abstract：:Prescription opioid analgesics are an important treatment option for patients with chronic pain; however, misuse, abuse and diversion of these medications are a major global public health concern. Prescription opioid analgesics can be abused via intended and non-intended routes of administration, both intact or after ...

journal_title：Postgraduate medicine

authors： Gasior M,Bond M,Malamut R

更新日期：2016-01-01 00:00:00

abstract：:Pregnancy is an important risk factor for venous thrombosis, and venous thromboembolism is a leading cause of preventable death in pregnancy. Diagnosis of venous thromboembolism is complicated in that the symptoms of dyspnea and lower extremity edema are relatively common complaints of pregnant patients. Physicians sh...

journal_title：Postgraduate medicine

authors： Sellman JS,Holman RL

更新日期：2000-09-15 00:00:00

abstract：:Many patients who require evaluation for coronary artery disease are unable to undergo exercise stress testing because of physiologic or psychological limitations. Drs Vacek and Baldwin describe three alternative methods for assessment of cardiac function in these patients, all of which have high levels of diagnostic ...

journal_title：Postgraduate medicine

authors： Vacek JL,Baldwin T

更新日期：1989-09-15 00:00:00

abstract：:Lyme disease can be difficult to recognize because not all patients have erythema migrans or other classic symptoms. Therefore, laboratory testing has become an important aid to clinical diagnosis. But the story doesn't end there-serologic testing presents another set of problems and concerns. Drs. Still and Ryan expl...

journal_title：Postgraduate medicine

authors： Still MM,Ryan ME

更新日期：1997-07-01 00:00:00

abstract：:The diagnostic survey of the infertile couple usually takes about three months. After semen analysis, the husband is referred for general and urologic examination. The wife is given a general physical and pelvic examination and returns during the next two months for ovulation studies. Tubal patency tests are also perf...

journal_title：Postgraduate medicine

authors： Cohen MR

更新日期：1977-10-01 00:00:00

abstract：:Oculoglandular syndrome and swelling of the parotid gland are unusual manifestations of cat-scratch disease. Although exposure to cats is considered an important part of the patient history, an actual cat scratch is not required to establish the diagnosis. Oral fluoroquinolones show promise in the treatment of the inf...

journal_title：Postgraduate medicine

authors： Tobin EH,McDaniel H

更新日期：1992-04-01 00:00:00

abstract：:In recent years bone marrow transplantation has become increasingly feasible for treating adult acute leukemia unresponsive to chemotherapy. However, the technique is not without significant intrinsic morbidity. The mouth is a singularly sensitive reflector of the cytotoxic, infectious, and hemorrhagic complications a...

journal_title：Postgraduate medicine

authors： Dreizen S,McCredie KB,Dicke KA,Zander AR,Peters LJ

更新日期：1979-11-01 00:00:00

abstract：OBJECTIVES:There are no evidence-based recommendations to screen for iron deficiency in non-anemic patients, even though symptoms may be present. The aim of this study is to measure the prevalence of iron deficiency (ID) without anemia in the general population aged 18-50 presenting to primary care along with the incid...

journal_title：Postgraduate medicine

authors： Abuaisha M,Itani H,El Masri R,Antoun J

更新日期：2020-04-01 00:00:00

abstract：:The urine of less than 3% of healthy persons shows more than three red cells per high-power field, which is about the limit of sensitivity of test strips for occult blood. Even minimal hematuria may herald serious problems and must be investigated. Common causes include infection, urethritis, and urethrotrigonitis (25...

journal_title：Postgraduate medicine

authors： Brown DC

更新日期：1987-09-15 00:00:00

abstract：:The goal of screening for colorectal cancer is to find early, asymptomatic cancers and adenomatous polyps that are 1 cm or more in diameter or that are villous or tubulovillous histologically. A study using fecal occult blood testing with rehydration and no sigmoidoscopy found that deaths from colorectal cancer can be...

journal_title：Postgraduate medicine

authors： Lush DT

更新日期：1994-07-01 00:00:00

abstract：:Exercise-induced asthma can appear as one of many forms of airway hyperreactivity or as a unique clinical entity. Simple spirometry confirms the suspected clinical diagnosis in most instances, although more sensitive measurements of airway obstruction may be required. In general, the asthmatic need not restrict physic...

journal_title：Postgraduate medicine

authors： Gerhard H,Schachter EN

更新日期：1980-03-01 00:00:00

abstract：:Preview There is considerable overlap in features and treatment of chronic obstructive pulmonary disease and asthma. Why, then, is it necessary to distinguish between the two? As the authors explain, the two diseases have different causes, risk factors, and clinical courses. Correct diagnosis, described in this articl...

journal_title：Postgraduate medicine

authors： Subramanian D,Guntupalli KK

更新日期：1994-06-01 00:00:00

abstract：:Although a great deal of investigation has led to some novel approaches in treating primary sclerosing cholangitis (PSC) and primary biliary cirrhosis (PBC), no method has been proven to definitively alter the long-term outcome of either disease. In addition, many of the medical regimens reviewed in this article have ...

journal_title：Postgraduate medicine

authors： Fennerty MB

更新日期：1993-11-01 00:00:00

abstract：:Because of the broad range of physiologic problems and the many potential sources of complications, liver transplantation patients require contributions from virtually the complete spectrum of medical science. The evolving specialty of liver transplantation has eagerly assimilated advances in surgical techniques, anes...

journal_title：Postgraduate medicine

authors： Williams JW,Sabesin SM

更新日期：1990-02-01 00:00:00

abstract：:Nearly every healthcare reform plan introduced in Congress this year addresses medical malpractice. Although the tort reform goals in the plans may be similar, the methods of achieving them differ substantially. To highlight the areas that need to be resolved, we set up a dialogue between a physician and a plaintiff's...

journal_title：Postgraduate medicine

authors： Annis ER,Nace BJ

更新日期：1994-10-01 00:00:00