An association between Takotsubo cardiomyopathy and thyroid storm.

Abstract:

:A 65-year-old woman presented to the hospital with weight loss and diarrhea. A diagnosis of thyroid storm was established by the presence of fever, lethargy, tachycardia, heart failure (HF), and abnormal thyroid function tests. An acute coronary syndrome (ACS) was suspected because of anteroseptal ST-segment elevations on electrocardiogram and severe left ventricular (LV) dysfunction with apical dilation on echocardiogram. The ejection fraction (EF) was 25%. Treatment for ACS and HF was begun. Coronary arteriography revealed normal coronaries. Propylthiouracil and corticosteroids were added to treat thyrotoxicosis. On Day 4, repeat echocardiography confirmed an EF of 65% and complete resolution of LV dysfunction and cavity dilation. Reversible LV dysfunction and apical cavity dilation is consistent with Takotsubo cardiomyopathy. While commonly associated with psychological trauma, its association with thyroid storm has only been reported twice before. Knowledge of this possible association is of importance in establishing the diagnosis and instituting a proper treatment plan.

journal_name

Postgrad Med

journal_title

Postgraduate medicine

authors

Radhakrishnan A,Granato JE

doi

10.3810/pgm.2009.05.2012

subject

Has Abstract

pub_date

2009-05-01 00:00:00

pages

126-30

issue

3

eissn

0032-5481

issn

1941-9260

journal_volume

121

pub_type

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