Update on the clinical management of atrial fibrillation: guidelines and beyond.

Abstract:

:In clinical practice, atrial fibrillation (AF) is the most commonly encountered arrhythmia. With the aging of the US population, the number of patients with AF that physicians encounter will increase. Atrial fibrillation management involves a combination of rate- and rhythm-control strategies with thromboprophylaxis, a complicated endeavor given side effect profiles of treatments, patient comorbidities, and anticoagulation treatment requirements. Early treatment discontinuation and poor compliance with anticoagulation treatment are frequent and result in increased mortality, a 5-fold increased risk of ischemic stroke, decreased health-related quality of life, and decreased exercise capacity. In 2006, the American College of Cardiology/American Heart Association/European Society of Cardiology (ACC/AHA/ESC) provided guidelines for the management of patients with AF. Recently, the ACC Foundation, AHA, and Heart Rhythm Society released updates to these guidelines (January and February 2011). This article aims to assist physicians in improving the management of patients with AF by focusing on the main components of therapy as reflected in the guidelines, and by providing an update on new US Food and Drug Administration-approved treatments.

journal_name

Postgrad Med

journal_title

Postgraduate medicine

authors

Curtis AB

doi

10.3810/pgm.2011.11.2491

subject

Has Abstract

pub_date

2011-11-01 00:00:00

pages

7-20

issue

6

eissn

0032-5481

issn

1941-9260

journal_volume

123

pub_type

杂志文章,评审
  • Facial pain. 'Why does my face hurt, doctor?'.

    abstract::In addition to sinus and dental abnormalities and stress, several different neurologic conditions can cause facial pain. These include various neuroalgias (trigeminal, vagoglosso-pharyngeal, cranial), carotodynia, and optic neuritis. Pain characteristics and results of specific neurologic tests establish the diagnosis...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.1080/00325481.1990.11704523

    authors: Mandel S

    更新日期:1990-01-01 00:00:00

  • Evaluation of the bleeding patient.

    abstract::The evaluation of the bleeding patient starts with the integration of data from the history and physical examination. From this results either one probable explanation that can easily be substatniated by laboratory studies or, as more commonly occurs in practice, several possibilities that are reasonable and must be i...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1977.11712257

    authors: Marengo-Rowe AJ,Leveson JE

    更新日期:1977-07-01 00:00:00

  • Clinical practice guidelines for attention-deficit/hyperactivity disorder: a review.

    abstract::The prevalence and public health importance of attention-deficit/hyperactivity disorder (ADHD) as well as its impact on public health has led various groups to develop clinical practice guidelines (CPGs). Clinical practice guidelines are systematically developed statements designed to assist practitioner and patient d...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.2010.09.2203

    authors: Bukstein OG

    更新日期:2010-09-01 00:00:00

  • Measles in young adults. The case for vigorous pursuit of immunization.

    abstract::Although the incidence of measles has reached record low levels in the United States, measles continues to occur in young adults. No single public health measure can ensure immunity for young adults, as school immunization laws do for young children. Therefore, to eliminate measles in this age-group, clinicians must t...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1985.11698856

    authors: Amler RW,Orenstein WA

    更新日期:1985-01-01 00:00:00

  • Hand dermatitis. The perennial scourge.

    abstract::Hand eczema continues to bedevil both patients and physicians. While appropriate and judicious intervention minimizes aggravation, discomfort, and inconvenience, recurrences are frequent. Treatment with corticosteroids is often effective for irritant dermatitis. Efforts to avoid the irritant, protect the hands, and us...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.1998.01.276

    authors: Landow K

    更新日期:1998-01-01 00:00:00

  • New onset diabetes mellitus induced by statins: current evidence.

    abstract::The hydroxyl-methyl-glutaryl-coenzyme-A (HMG-CoA) reductase inhibitors of statin action are very effective and safe drugs, and they are widely used for the treatment of hyperlipidemia and the prevention of primary and secondary cardiovascular diseases (CVDs). However, recent meta-analyses of previous studies done with...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.1080/00325481.2017.1292107

    authors: Chrysant SG

    更新日期:2017-05-01 00:00:00

  • Neurologic syndromes from repetitive trauma at work.

    abstract::Overuse syndrome and peripheral nerve entrapment syndromes arise in work situations in which the body is stressed beyond its limits by cumulative, repetitive trauma. These syndromes arise in some nonwork situations as well. When such an injury occurs, prompt diagnosis, treatment, and retraining aid in returning the em...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1987.11700031

    authors: Mandel S

    更新日期:1987-11-01 00:00:00

  • Serologic markers: impact on early diagnosis and disease stratification in inflammatory bowel disease.

    abstract::Inflammatory bowel disease (IBD) is difficult to diagnose, and differentiating between ulcerative colitis (UC) and Crohn's disease (CD) can be challenging. Overlapping symptoms of UC and CD often delay diagnosis, despite availability of endoscopic, radiologic, and histologic tools. This delay in diagnosis is quite com...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.2010.07.2184

    authors: Arai R

    更新日期:2010-07-01 00:00:00

  • Otitis media with effusion in infants and children. Primary care concerns addressed from an otolaryngologist's perspective.

    abstract::In 90% of children, otitis media with effusion resolves within 3 months. When it persists longer, it is considered chronic. Initial treatment of chronic otitis media with effusion is repeated courses of antibiotics, and a short course of steroids may be appropriate. Use of antihistamines and decongestants has not been...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:

    authors: Terris MH,Magit AE,Davidson TM

    更新日期:1995-01-01 00:00:00

  • Infectious diseases and antibiotic resistance in long-term care facilities.

    abstract::Infectious diseases in the institutionalized elderly are emerging as 1 of the major issues challenging physicians treating adult patients. The most common syndromes encountered are nursing home-acquired pneumonia, urinary tract infections, and skin and soft tissue infections. As a complicating factor, immunocompromise...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.02.2001.suppl12.68

    authors: Bonomo RA

    更新日期:2001-02-01 00:00:00

  • Medical management of diabetic foot infections.

    abstract::Diabetic foot infections (DFIs) are a commonly encountered medical problem. They are associated with an increased frequency and length of hospitalization and risk for lower-extremity amputation. Furthermore, they have substantial economic consequences. Patients with diabetes mellitus are particularly susceptible to fo...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.2012.03.2541

    authors: Bader MS,Brooks A

    更新日期:2012-03-01 00:00:00

  • The parotid lump--don't biopsy it! An approach to avoiding misadventure.

    abstract::All lumps in the parotid region must be assumed to originate in the parotid gland. A mobile, superficial-appearing lesion cannot be assumed to be located just beneath the skin. Open incisional biopsy should never be used in approaching lumps in this region because of the danger of tumor seeding or damage to the facial...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1987.11699754

    authors: Olsen KD

    更新日期:1987-03-01 00:00:00

  • Fever of unknown origin. A strategic approach to this diagnostic dilemma.

    abstract::Fever of unknown origin (FUO) remains a challenging clinical problem despite recent advances in diagnostic tools and techniques. Because primary care physicians are often the first ones to encounter a case of FUO, it is important that they be familiar with the best strategy and steps for confronting this problem initi...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.2003.09.1497

    authors: Amin K,Kauffman CA

    更新日期:2003-09-01 00:00:00

  • Uncomplicated peptic ulcer disease. An overview of formation and treatment principles.

    abstract::The end point in peptic ulcer disease is a crater in the mucosa. The cause of gastric ulcers seems to be the breakdown of defensive factors, which then allows damage from endogenous and/or exogenous aggressive factors. Aggressive factors are more important in duodenal ulcer formation. Treatment options discussed herei...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.1080/00325481.1993.11701642

    authors: Ziller SA 3rd,Netchvolodoff CV

    更新日期:1993-03-01 00:00:00

  • The metabolic syndrome: mechanisms, epidemiology, and clinical implications.

    abstract::This article reviews the definition, mechanisms, epidemiology, and clinical sequelae of the metabolic syndrome and explores potential relationships between the metabolic syndrome, type 2 diabetes, and cardiovascular disease. Definitions for the metabolic syndrome proposed by the World Health Organization and the Natio...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.12.2003.suppl31.175

    authors:

    更新日期:2003-12-01 00:00:00

  • Mechanisms and possible causes of Alzheimer's disease.

    abstract::Alzheimer's disease has been found to be genetically transmitted. Structural changes in the disease include loss of neurons, specifically cholinergic and perhaps noradrenergic neurons. Functional connections among neurons are also lost. No cause has yet been determined, but slow viruses, autoimmune processes, and alum...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1983.11698359

    authors: Schmidt G

    更新日期:1983-04-01 00:00:00

  • What to do about pruritus scroti.

    abstract::Pruritus scroti is a common clinical disorder that is caused by various inflammatory disorders, infections, infestations, and neoplasms. Laboratory evaluation, including bacterial and fungal cultures, microscopic examination, skin biopsies, and measurement of blood glucose levels, is useful in establishing the diagnos...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1990.11716424

    authors: Kantor GR

    更新日期:1990-11-01 00:00:00

  • Parasitic bowel disease: three pathogens important in primary care.

    abstract::A high index of suspicion and careful application of diagnostic methods are essential for accurate diagnosis of parasitic bowel diseases. The varied clinical spectrum of giardiasis, amebiasis, and strongyloidiasis emphasizes the need to consider these pathogens when patients present with gastrointestinal complaints. G...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.1080/00325481.1982.11716069

    authors: Burns TW

    更新日期:1982-05-01 00:00:00

  • Office gynecology. Diagnostic survey of the infertile couple.

    abstract::The diagnostic survey of the infertile couple usually takes about three months. After semen analysis, the husband is referred for general and urologic examination. The wife is given a general physical and pelvic examination and returns during the next two months for ovulation studies. Tubal patency tests are also perf...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1977.11714654

    authors: Cohen MR

    更新日期:1977-10-01 00:00:00

  • Subxiphoid uniportal video-assisted thoracoscopic surgery for synchronous bilateral lung resection.

    abstract:OBJECTIVES:With advancements in medical imaging and current emphasis on regular physical examinations, multiple pulmonary lesions increasingly are being detected, including bilateral pulmonary lesions. Video-assisted thoracic surgery is an important method for treating such lesions. Most of video-assisted thoracic surg...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.2018.1398048

    authors: Yang X,Wang L

    更新日期:2018-01-01 00:00:00

  • Immunologically mediated lung diseases. Extrinsic allergic alveolitis and allergic bronchopulmonary aspergillosis.

    abstract::Early recognition and treatment of immunologically mediated diseases of the lung are vital to prevent irreparable damage. Extrinsic allergic alveolitis and allergic bronchopulmonary aspergillosis are often confused but should not be difficult to distinguish. The former is nonatopic and is marked by chills, fever, ches...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1976.11714331

    authors: Slavin RG

    更新日期:1976-04-01 00:00:00

  • Listerial meningitis and renal allografts: a life-threatening affinity.

    abstract::Two cases of Listeria monocytogenes infection in patients receiving immunosuppressive treatment after kidney transplantation are described. In the first, the infection, which occurred soon after transplantation and was accompanied by signs of mild chronic rejection, was the immediate cause of death. The other case occ...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1980.11715622

    authors: Holden FA,Kaczmer JE,Kinahan CC

    更新日期:1980-12-01 00:00:00

  • Common eye disorders: six patients to treat, pitfalls to avoid.

    abstract::Primary care physicians have an important role in diagnosing and treating eye disorders--including dacryocystitis, blepharitis, and conjunctivitis--and in determining when ophthalmologic referral is needed. Fundus examination for diagnosis of glaucoma and diabetic eye complications should be a part of the routine exam...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:

    authors: Weinstock FJ,Weinstock MB

    更新日期:1996-04-01 00:00:00

  • Wound healing. Helping a natural process.

    abstract::Wound healing calls for little outside interference. All the physician need do is ensure that the wound is clean and debrided and decide whether closure by suture or by granulation tissue formation is indicated. Suture repair should be delayed if the wound is heavily contaminated. Use of skin tapes or of constant-pres...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1983.11698475

    authors: Fernandez A,Finley JM

    更新日期:1983-10-01 00:00:00

  • Basics of joint injection. General techniques and tips for safe, effective use.

    abstract::Successful joint and soft-tissue aspiration and injection rely on the physician's understanding of the indications, contraindications, and general techniques involved in these procedures. The procedures are generally well tolerated and can be used to treat many painful musculoskeletal and soft-tissue conditions. ...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.2001.01.834

    authors: Rifat SF,Moeller JL

    更新日期:2001-01-01 00:00:00

  • Cardiovascular risk in chronic kidney disease: what is new in the pathogenesis and treatment?

    abstract::The prevalence of chronic kidney disease (CKD) has increased markedly over past decades due to the aging of the worldwide population. Despite the progress in the prevention and treatment, the cardiovascular (CV) morbidity and mortality remain high among patients with CKD. Although CKD is a progressive and irreversible...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.1080/00325481.2018.1481714

    authors: Bazyluk A,Malyszko J,Zbroch E

    更新日期:2018-06-01 00:00:00

  • Hormone abnormalities in patients with severe and chronic pain who fail standard treatments.

    abstract::Some patients with severe and chronic pain fail to obtain adequate pain relief with standard pharmacologic treatment agents, including low to moderate dosages of opioids. Understandably, physicians might not believe patients who claim that a standard opioid dosage is an ineffective treatment. These patients may be sev...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.2014.996110

    authors: Tennant F

    更新日期:2015-01-01 00:00:00

  • Effects of omeprazole on the pharmacokinetic profiles of lisdexamfetamine dimesylate and extended-release mixed amphetamine salts in adults.

    abstract:OBJECTIVE:To evaluate the pharmacokinetics of lisdexamfetamine dimesylate (LDX), a long-acting prodrug stimulant, and mixed amphetamine salts extended-release (MAS XR), alone or with omeprazole, a proton pump inhibitor (PPI). METHODS:This open-label, randomized, 4-period crossover study enrolled healthy adults (18-45 ...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.3810/pgm.2009.09.2048

    authors: Haffey MB,Buckwalter M,Zhang P,Homolka R,Martin P,Lasseter KC,Ermer JC

    更新日期:2009-09-01 00:00:00

  • Meningococcal vaccination: a discussion with all adolescents, whether college-bound or not.

    abstract::Introduction: Adolescents and young adults are the primary reservoirs and transmitters of meningococci. In the US, meningococcal serogroup B (MenB) disease predominates over A, C, W, and Y; ACIP-recommended MenACWY and MenB vaccines are available. We investigated invasive meningococcal disease (IMD) burden and vaccina...

    journal_title:Postgraduate medicine

    pub_type: 社论

    doi:10.1080/00325481.2019.1671667

    authors: Alderfer JT,Moran MM,Srivastava A,Isturiz RE

    更新日期:2019-11-01 00:00:00

  • Severe Pseudomonas aeruginosa infections. Tackling the conundrum of drug resistance.

    abstract::Pseudomonas aeruginosa infections are a frequent cause of morbidity and mortality in hospitalized patients. Treatment of these infections is complicated by the intrinsic and acquired resistance of this bacterium to many commonly used antimicrobial agents. In this article, Drs Hauser and Sriram argue that careful consi...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.2005.01.1571

    authors: Hauser AR,Sriram P

    更新日期:2005-01-01 00:00:00