Thromboembolism during pregnancy. Risks, challenges, and recommendations.

Abstract:

:Pregnancy is an important risk factor for venous thrombosis, and venous thromboembolism is a leading cause of preventable death in pregnancy. Diagnosis of venous thromboembolism is complicated in that the symptoms of dyspnea and lower extremity edema are relatively common complaints of pregnant patients. Physicians should maintain an appropriately high index of suspicion and request diagnostic imaging in a timely manner. Diagnosis of deep venous thrombosis with Doppler ultrasonography of the lower extremity poses no health risk to the fetus, but other radiographic studies pose a low radiation risk to the fetus. Because anticoagulant therapy poses a greater health risk to mother and fetus than does the radiation required for the diagnosis of pulmonary embolism, clinicians should aggressively pursue objective evidence of venous thromboembolism. Once the diagnosis is made, anticoagulation with intravenous unfractionated heparin or subcutaneous low-molecular-weight heparin should be used prepartum followed by warfarin therapy after delivery.

journal_name

Postgrad Med

journal_title

Postgraduate medicine

authors

Sellman JS,Holman RL

doi

10.3810/pgm.2000.09.15.1238

subject

Has Abstract

pub_date

2000-09-15 00:00:00

pages

71-2, 77-8, 81-4

issue

4

eissn

0032-5481

issn

1941-9260

journal_volume

108

pub_type

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