The aging process.

Abstract:

:Preview Although no one theory on aging explains satisfactorily why or how this process occurs, we know that aging causes physiologic changes and a progressive decline of functional organ reserve. The implications of these changes are increasingly important as the elderly segment of the population grows. In this article, Dr Troncale discusses the aging process and its effects, particularly in regard to drug therapy.

journal_name

Postgrad Med

journal_title

Postgraduate medicine

authors

Troncale JA

doi

10.1080/00325481.1996.11946121

subject

Has Abstract

pub_date

1996-05-01 00:00:00

pages

111-122

issue

5

eissn

0032-5481

issn

1941-9260

journal_volume

99

pub_type

杂志文章
  • Malnutrition, inflammation, and lipids in a cohort of dialysis patients.

    abstract:BACKGROUND:This study aimed to determine if there is an association between lipid levels, serum albumin, and C-reactive protein (CRP) levels in patients on dialysis. METHODS:Lipid profiles, albumin, and CRP levels were collected after a 12-hour fast from patients with end-stage renal disease (N = 105) who were on chro...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.3810/pgm.2010.05.2158

    authors: Bowden RG,Wilson RL

    更新日期:2010-05-01 00:00:00

  • Evaluating peripheral arterial occlusive disease.

    abstract::The clinical history and physical examination remain the most important factors in determining the presence, anatomic location, and physiologic extent of arterial occlusive disease and the need for operation. The physician should refrain from ordering arteriography to confirm the diagnosis of arterial disease unless o...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1976.11714271

    authors: Barnes RW

    更新日期:1976-02-01 00:00:00

  • Diagnosing obstructive lung disease.

    abstract::Preview There is considerable overlap in features and treatment of chronic obstructive pulmonary disease and asthma. Why, then, is it necessary to distinguish between the two? As the authors explain, the two diseases have different causes, risk factors, and clinical courses. Correct diagnosis, described in this articl...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1994.11945862

    authors: Subramanian D,Guntupalli KK

    更新日期:1994-06-01 00:00:00

  • Optimal treatment of hypertension in African Americans. Reaching and maintaining target blood pressure goals.

    abstract::Treatment of hypertension in African Americans has special challenges, including a lack of objective trial data on which to base decisions and differing benefits and responses than with other patients. However, adequate control is possible and should be the goal of treating physicians. This article describes current "...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.2002.10.1333

    authors: Bakris GL,Ferdinand KC,Douglas JG,Sowers JR

    更新日期:2002-10-01 00:00:00

  • The worst headache ever. 2. Innocuous causes.

    abstract::In most cases, patients presenting with "the worst headache ever" are found to have a benign condition, notably migraine, toxic vascular headache, or exertion-induced headache. However, ominous causes first must be excluded by appropriate investigation, such as computed tomographic or magnetic resonance imaging scans ...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.1080/00325481.1989.11704328

    authors: Edmeads J

    更新日期:1989-07-01 00:00:00

  • Gastroesophageal reflux and asthma.

    abstract::Gastroesophageal reflux provokes asthma in many patients. Conversely, asthma predisposes to gastroesophageal reflux. In many patients, reflux therapy will ameliorate asthma. Recognition of this relationship is facilitated by physician awareness, clinical history, selected laboratory tests, and ultimately, a careful mo...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.1080/00325481.1989.11704343

    authors: Mansfield LE

    更新日期:1989-07-01 00:00:00

  • Drug-induced illness in the elderly.

    abstract::The elderly are predisposed to adverse drug reactions because of age-related physiologic changes, interaction of one drug with another, and interaction between a drug and a coexisting medical condition. Recognition of such adverse reactions is essential, because many are reversible and many are even preventable. Asses...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.1080/00325481.1989.11704370

    authors: Harper CM,Newton PA,Walsh JR

    更新日期:1989-08-01 00:00:00

  • Sports injuries. Practical diagnostic and management concerns for primary care physicians.

    abstract::Both recreational and elite athletes often sustain musculoskeletal injuries. Common problems--muscle cramps, burners (or stingers), and ankle and shoulder injuries--can be managed effectively with certain basic techniques. Initial measures are particularly important in facilitating the injured athlete's rapid return t...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:

    authors: Sellers RG

    更新日期:1992-08-03 00:00:00

  • Routes of abuse of prescription opioid analgesics: a review and assessment of the potential impact of abuse-deterrent formulations.

    abstract::Prescription opioid analgesics are an important treatment option for patients with chronic pain; however, misuse, abuse and diversion of these medications are a major global public health concern. Prescription opioid analgesics can be abused via intended and non-intended routes of administration, both intact or after ...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.1080/00325481.2016.1120642

    authors: Gasior M,Bond M,Malamut R

    更新日期:2016-01-01 00:00:00

  • Comparison of subjective effects of extended-release versus immediate-release oxycodone/acetaminophen tablets in healthy nondependent recreational users of prescription opioids: a randomized trial.

    abstract:BACKGROUND:Prescription opioids have substantial abuse potential. This study compared the positive subjective drug effects of a newly developed extended-release (ER) oxycodone (OC)/acetaminophen (acetyl-para-aminophenol [APAP]) formulation with those of immediate-release (IR) OC/APAP. METHODS:This randomized, double-b...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.3810/pgm.2014.07.2780

    authors: Morton T,Kostenbader K,Montgomery J,Devarakonda K,Barrett T,Webster L

    更新日期:2014-07-01 00:00:00

  • Rapid evaluation of comatose patients.

    abstract::Coma is a common, life-threatening medical problem encountered by primary care physicians. The principles of emergency management mandate that adequate oxygenation, blood flow, and supplementation with thiamine and glucose be given to the brain before a thorough diagnostic evaluation is undertaken. Knowledge of the us...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1990.11716346

    authors: Alguire PC

    更新日期:1990-05-01 00:00:00

  • Relationship between sleep disorders and the risk for developing type 2 diabetes mellitus.

    abstract::Sleep is increasingly being recognized as an important factor in the homeostasis of multiple body functions, including blood glucose metabolism. One of the most common sleep disorders, obstructive sleep apnea, is not only highly prevalent in patients with type 2 diabetes mellitus, but may contribute to the development...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.2012.07.2573

    authors: Ioja S,Weir ID,Rennert NJ

    更新日期:2012-07-01 00:00:00

  • Treatment of Parkinson's disease.

    abstract::Preview Although the early symptoms of Parkinson's disease can be ameliorated, the illness is relentlessly progressive. Studies have therefore been conducted in hopes of finding therapy to delay its disabling course. In this article, Dr Ahlskog examines recent proposals and their application in cases of early and adva...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1994.11945830

    authors: Ahlskog JE

    更新日期:1994-05-01 00:00:00

  • Managing obesity like any other chronic condition. Long-term therapy may reduce comorbidity as well.

    abstract::Patients often seek help from their primary care physician for weight loss, so familiarity with pharmacologic options and their risks is important. Anorexiants have been available for decades and are relatively safe. Orlistat and sibutramine are two of the newer medications that patients may have heard about in televi...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.2000.07.1158

    authors: Agrawal M,Worzniak M,Diamond L

    更新日期:2000-07-01 00:00:00

  • Efficacy and renal outcomes of SGLT2 inhibitors in patients with type 2 diabetes and chronic kidney disease.

    abstract:OBJECTIVE:To review glucose-lowering efficacy and changes in renal function associated with sodium-glucose co-transporter 2 (SGLT2) inhibitors among patients with chronic kidney disease (CKD) and type 2 diabetes mellitus (T2DM). DATA SOURCES:A literature search of MEDLINE and Cochrane databases was performed from 2000...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.1080/00325481.2019.1549459

    authors: Kelly MS,Lewis J,Huntsberry AM,Dea L,Portillo I

    更新日期:2019-01-01 00:00:00

  • Principles of therapeutic drug monitoring.

    abstract::Biochemical monitoring is generally advised for drugs that are potentially toxic, have a narrow therapeutic range, or are prescribed for life-threatening disease. Monitoring should not be attempted until the serum concentration reaches a plateau, or steady state, and sampling must be timed carefully. Besides incorrect...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1981.11715801

    authors: Burke MD

    更新日期:1981-07-01 00:00:00

  • HPV and cervical cancer: updates on an established relationship.

    abstract::Despite cervical cancer being considered a preventable disease, it still remains the second most common malignancy in women worldwide, with a higher incidence in underdeveloped countries. Human papillomavirus (HPV) is considered the causative agent of cervical cancer. The major mechanisms through which HPV contributes...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.2008.11.1928

    authors: Subramanya D,Grivas PD

    更新日期:2008-11-01 00:00:00

  • Aspirin sensitivity. A distressing reaction that is now often treatable.

    abstract::Aspirin-induced hypersensitivity affects a substantial number of people, including 20% or more of asthmatic patients. A dramatic flare of symptoms occurs after indigestion of aspirin or a nonsteroidal anti-inflammatory drug, and symptoms can persist even after the agent is discontinued. Fortunately, aspirin desensitiz...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1991.11701086

    authors: Manning ME,Stevenson DD

    更新日期:1991-10-01 00:00:00

  • The cochlear prosthesis. Bringing the world of sound to the deaf.

    abstract::The complexity of coding in the auditory nerve makes it unlikely that a prosthesis for deaf persons can exactly duplicate the normal function of the ear. With recent advances, however, cochlear prostheses can perform some of the frequency-analysis functions of the normal ear. Cochlear prostheses are effective aids to ...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1984.11698797

    authors: Farrar CL,Mangham CA Jr,Kuprenas SV

    更新日期:1984-11-15 00:00:00

  • Rocky Mountain spotted fever. When and why to consider the diagnosis.

    abstract::Rocky Mountain spotted fever, caused by a rickettsial organism transmitted by the bite of a tick, can be confused with many more common diseases. Diagnosis is made more challenging by the fact that treatment is most efficacious if begun before the second week of illness. Tetracycline and doxycycline are the most succe...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1990.11704599

    authors: Fischer JJ

    更新日期:1990-03-01 00:00:00

  • Clinical and economic outcomes in respiratory tract infections: The impact of bacterial resistance.

    abstract::Drug acquisition cost is an important component in the analysis of economic and clinical outcomes in the treatment of respiratory tract infections (RTIs). However, bacterial resistance has emerged as a crucial variable that must also be considered. Drug-resistant infections result in more expensive drug therapy, longe...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.3810/pgm.09.2002.suppl19.100

    authors: Rapp RP

    更新日期:2002-09-01 00:00:00

  • An overview of stroke. Epidemiology, classification, risk factors, clinical aspects.

    abstract::Although evidence indicates that the incidence of stroke has declined over the past 30 years, stroke remains one of the leading causes of disability and death in the United States. Prevention appears to be the best treatment. According to the Straub Stroke Registry, 52% of strokes in its patient population can be attr...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1986.11699535

    authors: Nakano KK

    更新日期:1986-09-15 00:00:00

  • Prevention of myocardial reinfarction.

    abstract::Preview The number of cardiac drugs is growing every day, and their indications are changing as more is learned about each one. Choosing the appropriate drug for each patient is made difficult by these complexities, especially when a patient has already had a heart attack. The authors review the latest trials of the m...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1993.11945746

    authors: Flaker GC,Singh VN

    更新日期:1993-11-01 00:00:00

  • A checklist for evaluation of HIV-infected patients.

    abstract::To aid in making care of HIV-infected patients part of your office routine, Dr Coodley presents here a checklist that combines the various clinical aspects of initial management. Covering the steps from the history to plans for follow-up, this article should allay anxiety and promote confidence in your entire staff by...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.1080/00325481.1993.11701640

    authors: Coodley GO

    更新日期:1993-03-01 00:00:00

  • Pelvic inflammatory disease. Current diagnostic criteria and treatment guidelines.

    abstract::Pelvic inflammatory disease (PID) is a common infection in women of reproductive age. PID is actually a spectrum of disease, beginning with cervicitis and progressing to endometritis and eventually salpingitis. Sequelae include ectopic pregnancy, infertility, chronic pelvic pain, hydrosalpinx, and tubo-ovarian abscess...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.1080/00325481.1993.11701600

    authors: Ault KA,Faro S

    更新日期:1993-02-01 00:00:00

  • What to do about pruritus scroti.

    abstract::Pruritus scroti is a common clinical disorder that is caused by various inflammatory disorders, infections, infestations, and neoplasms. Laboratory evaluation, including bacterial and fungal cultures, microscopic examination, skin biopsies, and measurement of blood glucose levels, is useful in establishing the diagnos...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1990.11716424

    authors: Kantor GR

    更新日期:1990-11-01 00:00:00

  • Advances in refractive surgery. New options expand the scope of corrective procedures.

    abstract::The Food and Drug Administration's approval of the excimer laser in 1995 heralded the age of laser refractive surgery in the United States. Since then, other advances in refractive surgery have spurred great public interest in and enthusiasm for these procedures. In this article, the authors review the major types of ...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.1999.09.683

    authors: Chaudhry IM,Conti ER,Steinert RF

    更新日期:1999-09-01 00:00:00

  • Hyperbaric oxygen therapy. Promoting healing in difficult cases.

    abstract::Inhalation of pressurized 100% oxygen is a helpful adjunctive treatment for certain patients, because the increased oxygen carried by the blood to the tissue enhances new growth of microcirculation and, thus, healing. Patients with tissue breakdown after radiation therapy, refractory osteomyelitis, gas gangrene, soft-...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1986.11699267

    authors: Cohn GH

    更新日期:1986-02-01 00:00:00

  • Essential echocardiographic evaluation in patients with suspected pulmonary hypertension: an overview for the practicing physician.

    abstract::Prompt and accurate diagnosis of patients presenting with symptoms suggestive of pulmonary arterial hypertension (PAH) is of outmost importance as delays in identifying this clinical entity have detrimental effects on both morbidity and mortality. Initial noninvasive assessment of these patients has traditionally incl...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.1080/00325481.2016.1115715

    authors: Vargas PE,Lopez-Candales A

    更新日期:2016-01-01 00:00:00

  • Update on traveler's diarrhea.

    abstract::Traveler's diarrhea affects a substantial number of travelers to high-risk areas of the world. The key to controlling this troublesome disease is prevention. The most important preventive measures depend on educating patients to consume only safe foods and pure water. Physicians cannot overemphasize the importance of ...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1988.11700344

    authors: Strum WB

    更新日期:1988-07-01 00:00:00