The radiation environment in low-Earth orbit.

abstract：:Radiation exposure leads to a risk for long-term deterministic and stochastic late effects. Two individuals exposed to protracted photon radiation in the radiological accident at the Lilo Military site in Georgia in 1997 received follow-up treatment and resection of several chronic radiation ulcers in the Bundeswehr H...

journal_title：Radiation research

authors： Scherthan H,Abend M,Müller K,Beinke C,Braselmann H,Zitzelsberger H,Köhn FM,Pillekamp H,Schiener R,Das O,Peter RU,Herzog G,Tzschach A,Dörr HD,Fliedner TM,Meineke V

更新日期：2007-05-01 00:00:00

abstract：:Using an electron storage ring as a source of radiation, the wavelength dependence of inactivation and membrane damage in yeast cells (Saccharomyces cerevisiae) was investigated in the range from 145 to 254 nm, with special reference to the effects of vacuum-uv radiation. The cells were irradiated on a Millipore filte...

journal_title：Radiation research

authors： Ito T,Ito A,Hieda K,Kobayashi K

更新日期：1983-12-01 00:00:00

abstract：:The German Thorotrast study comprises 2,326 patients and 1,890 controls. Forty-eight Thorotrast patients and 239 controls are still alive and are invited for a follow-up examination every 2 years. In the deceased patients, the following neoplastic diseases with excess rates were registered (Thorotrast/controls): liver...

journal_title：Radiation research

authors： van Kaick G,Dalheimer A,Hornik S,Kaul A,Liebermann D,Lührs H,Spiethoff A,Wegener K,Wesch H

更新日期：1999-12-01 00:00:00

abstract：:Radiation-induced complications in bone and cartilage are of increasing concern due to potential long-term effects in cancer survivors. Healthy articular cartilage may be exposed to radiation during either chondrosarcoma treatment or in-field radiotherapy of tumors located in close proximity to articulation. Cartilage...

journal_title：Radiation research

authors： Saintigny Y,Cruet-Hennequart S,Hamdi DH,Chevalier F,Lefaix JL

更新日期：2015-02-01 00:00:00

abstract：:Domestic radon risk estimates are typically based either on data for uranium miners or on data derived from A-bomb survivors; comparison of domestic radon risk estimates derived from these two disparate sources represents an important test of their reliability. There is currently a significant discrepancy of about a f...

journal_title：Radiation research

authors： Brenner DJ,Miller RC,Huang Y,Hall EJ

更新日期：1995-04-01 00:00:00

abstract：:In this study, we investigated the accuracy of using off-line bioluminescence imaging (BLI) and tomography (BLT) to guide irradiation of small soft tissue targets on a small animal radiation research platform (SARRP) with on-board cone beam CT (CBCT) capability. A small glass bulb containing BL cells was implanted as ...

journal_title：Radiation research

authors： Tuli R,Armour M,Surmak A,Reyes J,Iordachita I,Patterson M,Wong J

更新日期：2013-02-22 00:00:00

abstract：:The effects of X irradiation on oligodendrocyte-type-2-astrocyte (O-2A) progenitor cells derived from different regions of the perinatal central nervous system (CNS) of rats were investigated in vitro. The O-2A progenitor cells can differentiate into either oligodendrocytes or type-2 astrocytes. The depletion of these...

journal_title：Radiation research

authors： van der Maazen RW,Kleiboer BJ,Verhagen I,van der Kogel AJ

更新日期：1991-10-01 00:00:00

abstract：:While the risk of lung cancer associated separately with smoking and radiation exposure has been widely reported, it is not clear how smoking and radiation together contribute to the risk of specific lung cancer histological types. With individual smoking histories and radiation dose estimates, we characterized the jo...

journal_title：Radiation research

authors： Egawa H,Furukawa K,Preston D,Funamoto S,Yonehara S,Matsuo T,Tokuoka S,Suyama A,Ozasa K,Kodama K,Mabuchi K

更新日期：2012-09-01 00:00:00

abstract：:Gleevec, a selective tyrosine kinase inhibitor, retarded the growth of anaplastic thyroid cancer cell lines in vitro and in vivo through selective inhibition of ABL tyrosine kinase activity. In the present study, we investigated the ability of Gleevec to modulate the in vitro and in vivo radiation response of anaplast...

journal_title：Radiation research

authors： Podtcheko A,Ohtsuru A,Namba H,Saenko V,Starenki D,Palona I,Sedliarou I,Rogounovitch T,Yamashita S

更新日期：2006-01-01 00:00:00

abstract：:Molecular oxygen has long been recognized as a powerful radiosensitizer that enhances the cell-killing efficiency of ionizing radiation. Radiosensitization by oxygen occurs at very low concentrations with the half-maximum radiosensitization at approximately 3 mmHg. However, robust hypoxia-induced signal transduction c...

journal_title：Radiation research

authors： Liu C,Lin Q,Yun Z

更新日期：2015-05-01 00:00:00

abstract：:The induction of chromosome aberrations in human lymphocytes irradiated in vitro with X rays generated at a tube voltage of 29 kV was examined to assess the maximum low-dose RBE (RBE(M)) relative to higher-energy X rays or 60Co gamma rays. Since blood was taken from the same male donor whose blood had been used for pr...

journal_title：Radiation research

authors： Schmid E,Regulla D,Kramer HM,Harder D

更新日期：2002-12-01 00:00:00

abstract：:The concept of curvature in dose-response relationships figures prominently in radiation biology, encompassing a wide range of interests including radiation protection, radiotherapy and fundamental models of radiation action. In this context, the ability to detect even small amounts of curvature becomes important. Sta...

journal_title：Radiation research

authors： Shuryak I,Loucas BD,Cornforth MN

更新日期：2017-01-01 00:00:00

abstract：:Ionizing radiations induce mutations which can be detected both in coding sequences (Hprt locus) by measuring the frequency of 6-thioguanine-resistant cells and in minisatellite sequences by DNA fingerprint analysis. We analyzed the effects of irradiation with low-energy protons (31 keV/pm) and, for comparison, with u...

journal_title：Radiation research

authors： Ogheri S,Bruna V,Cera F,Favaretto S,Cherubini R,Celotti L

更新日期：1997-09-01 00:00:00

abstract：:To investigate whether exposure to atomic bomb radiation altered the prevalence of hepatitis C virus (HCV) infection or accelerated the progress toward chronic hepatitis after HCV infection, the seropositivity of antibody to hepatitis C virus (anti-HCV) was determined for 6,121 participants in the Adult Health Study o...

journal_title：Radiation research

authors： Fujiwara S,Kusumi S,Cologne J,Akahoshi M,Kodama K,Yoshizawa H

更新日期：2000-07-01 00:00:00

abstract：:The statistical distribution of the number of ion pairs per ionizing event in a small volume simulating a tissue sphere was obtained by applying the Expectation-Maximization (EM) algorithm to experimental spectra measured by exposing a Rossi-type spherical proportional counter to gamma radiation. The normalized experi...

journal_title：Radiation research

authors： Obelić B,Srdoc D,Djurić PM,Marino SA

更新日期：1998-05-01 00:00:00

abstract：:Changes in the free-cell population of the lungs of two strains of mice (SAS/4 and CBA/H) were studied up to 4 months after inhalation exposure to a sized fraction of 239PuO2 particles (1.5 micron AMAD) to give initial alveolar depositions (IADs) ranging from 17 to 810 Bq. A sample of the free-cell population of the l...

journal_title：Radiation research

authors： Moores SR,Talbot RJ,Evans N,Lambert BE

更新日期：1986-03-01 00:00:00

abstract：:Mutation and killing induced by X radiation and 60CO gamma radiation were studied in six different histidine-requiring auxotrophs of Salmonella typhimurium. Strain TA100, which is sensitive to base-pair substitutions, and strains TA2637 and TA98, which are sensitive to frameshifts, carry the pKM101 plasmid and exhibit...

journal_title：Radiation research

authors： Isildar M,Bakale G

更新日期：1984-11-01 00:00:00

abstract：:Single crystals of disodium beta-glycerophosphate pentahemihydrate (betaGP), Na2x(HO)CH2CH(PO(4)2-)CH2(OH)x5 1/2H2O, were X-irradiated at 77 and 280 K. EPR, ENDOR and FSE techniques were used to study the formation of free radicals in these irradiated crystals to characterize possible reaction mechanisms leading to de...

journal_title：Radiation research

authors： Baine TJ,Sagstuen E

更新日期：1998-08-01 00:00:00

abstract：:Dose-response relationships for X-ray-induced reciprocal translocations in spermatogonial stem cells of mutant and wild-type mice were established by spermatocyte analysis many cell generations after irradiation. The mutants studied were Wv/+, the viable allele of dominant spotting in the heterozygous state, and Slcon...

journal_title：Radiation research

authors： van Buul PP,Schöppink K,de Rooij DG,Seelen MC

更新日期：1994-02-01 00:00:00

abstract：:Radiation therapy is an essential component of cancer treatment. Currently, tumor control and normal tissue complication probabilities derived from a general patient population guide radiation treatment. Its outcome could be improved if radiation biomarkers could be incorporated into approaches to treatment. A substan...

journal_title：Radiation research

authors： Prasanna PGS,Narayanan D,Zhang K,Rahbar A,Coleman CN,Vikram B

更新日期：2020-03-01 00:00:00

abstract：:Exposure to ionizing radiation alone or combined with traumatic tissue injury is a crucial life-threatening factor in nuclear and radiological incidents. Radiation injuries occur at the molecular, cellular, tissue and systemic levels; their mechanisms, however, remain largely unclear. Exposure to radiation combined wi...

journal_title：Radiation research

authors： Kiang JG,Zhai M,Bolduc DL,Smith JT,Anderson MN,Ho C,Lin B,Jiang S

更新日期：2017-11-01 00:00:00

abstract：:Radiation-induced acute myeloid leukemia (rAML) in C3H mice is commonly developed through inactivation of PU.1 transcription factor encoded in Sfpi1 on chromosome 2. PU.1 inactivation involves two steps: hemizygous deletion of the Sfpi1 gene (DSG) and point mutation of the allele Sfpi1 gene (PMASG). In this study, we ...

journal_title：Radiation research

authors： Ojima M,Hirouchi T,Etani R,Ariyoshi K,Fujishima Y,Kai M

更新日期：2019-12-01 00:00:00

abstract：:Keratinocyte growth factor (FGF7, also known as KGF) ameliorates the radiation response of mouse oral mucosa and other epithelial tissues. However, the precise mechanisms remain unclear. The aim of the present study was to investigate the effect of FGF7 on the survival and colony size of normal human epidermal keratin...

journal_title：Radiation research

authors： Slonina D,Hoinkis C,Dörr W

更新日期：2001-12-01 00:00:00

abstract：:Previous studies identified radiation therapy as a key modifier of basal cell carcinoma (BCC) risk in survivors of hematopoietic cell transplantation (HCT). In the present analysis, risk of BCC was analyzed in relation to age at transplant, attained age, race, total-body irradiation (TBI), and radiation fractionation ...

journal_title：Radiation research

authors： Schwartz JL,Kopecky KJ,Mathes RW,Leisenring WM,Friedman DL,Deeg HJ

更新日期：2009-02-01 00:00:00

abstract：:Hypoadrenocorticism, known as Addison's disease in humans, was diagnosed in six beagles after inhalation of at least 1.7 kBq/g lung of 238PuO2. Histological examination of adrenal gland specimens obtained at necropsy revealed marked adrenal cortical atrophy in all cases. Autoradiographs showed only slight alpha-partic...

journal_title：Radiation research

authors： Weller RE,Buschbom RL,Dagle GE,Park JF,Ragan HA,Watson CR

更新日期：1996-12-01 00:00:00

abstract：:We describe a rapid assay to predict intrinsic radiosensitivity of normal tissues based on the radiation-induced cytotoxic response of a number of types of white blood cells. Twenty-four hours after irradiation, leukocytes were prepared for analysis by flow cytometry. Radiation-induced cytotoxicity was characterized b...

journal_title：Radiation research

authors： Crompton NE,Ozsahin M

更新日期：1997-01-01 00:00:00

abstract：:Blockers of the renin-angiotensin-aldosterone system (RAAS) ameliorate cognitive deficits and some aspects of brain injury after whole-brain irradiation. We investigated whether treatment with the angiotensin II type 1 receptor antagonist L-158,809 at a dose that protects cognitive function after fractionated whole-br...

journal_title：Radiation research

authors： Conner KR,Forbes ME,Lee WH,Lee YW,Riddle DR

更新日期：2011-07-01 00:00:00

abstract：:Tissue-incorporated radionuclides impart radiation energy over extended periods of time depending on their effective half-lives. The capacity of vitamin A dissolved in soybean oil to protect against the biological effects caused by internal radionuclides is investigated. The radiochemicals examined are DNA-binding 125...

journal_title：Radiation research

authors： Harapanhalli RS,Narra VR,Yaghmai V,Azure MT,Goddu SM,Howell RW,Rao DV

更新日期：1994-07-01 00:00:00

abstract：:In this study, we assessed the efficacy of unilamellar 110-nm liposomes encapsulating the chelating agent diethylenetriaminepentaacetic acid (DTPA) in plutonium-exposed rats. Rats were contaminated by intravenous administration of the soluble citrate form of plutonium. The comparative effects of liposomal and free DTP...

journal_title：Radiation research

authors： Grémy O,Miccoli L,Lelan F,Bohand S,Cherel M,Mougin-Degraef M

更新日期：2018-05-01 00:00:00

abstract：:Ionizing radiation induces clustered DNA damage sites, whereby two or more individual DNA lesions are formed within one or two helical turns of DNA by a single radiation track. A subset of DNA clustered damage sites exist in which the lesions are located in tandem on the same DNA strand. Recent studies have establishe...

journal_title：Radiation research

authors： Lomax ME,Salje H,Cunniffe S,O'Neill P

更新日期：2005-01-01 00:00:00