Abstract：
BACKGROUND:Recurrence of adrenal cortical carcinoma (ACC) after radical surgery is a common finding. Although successful reoperations have been reported with encouraging results, most published experiences are anecdotal and based on few cases. We report the results of surgical treatment for recurrent ACC in a multiinstitutional series. METHODS:One hundred eighty-eight cases of ACC were collected in a national registry. A complete follow-up was obtained in 179 cases. At initial diagnosis 92 patients had local disease (stage I or II). One hundred seventy patients underwent surgical treatment, considered radical in 140; in this group, recurrent disease was observed in 52 cases (37%) after a mean disease-free interval of 21.7 months. RESULTS:Adjuvant chemotherapy was ineffective in ameliorating the prognosis. The mean survival in 20 patients who underwent reoperation was significantly higher (15.85 +/- 14.9 months) than in nonreoperated cases (3.2 +/- 2.9 months). Five-year actuarial survival in reoperated patients is significantly better than in nonreoperated patients (49.7% versus 8.3%, respectively). CONCLUSIONS:Although the prognosis of this tumor is still poor, surgery is the only effective therapy; reoperation allows survival comparable to that observed in patients without recurrent disease. An aggressive strategy for recurrent ACC is advisable until prospective studies demonstrate a real effectiveness for chemotherapy.
journal_name
Surgeryjournal_title
Surgeryauthors
Bellantone R,Ferrante A,Boscherini M,Lombardi CP,Crucitti P,Crucitti F,Favia G,Borrelli D,Boffi L,Capussotti L,Carbone G,Casaccia M,Cavallaro A,Del Gaudio A,Dettori G,Di Giovanni V,Mazziotti A,Marrano D,Masenti E,Midoi
10.1016/s0039-6060(97)90229-4subject
Has Abstract,Author List Incompletepub_date
1997-12-01 00:00:00pages
1212-8issue
6eissn
0039-6060issn
1532-7361pii
S0039-6060(97)90229-4journal_volume
122pub_type
杂志文章相关文献
SURGERY文献大全abstract：:Two patient groups were studied to determine the need to preserve the greater saphenous vein during femoral outflow reconstruction for later aortocoronary bypass procedures. First, 74 patients were followed to the time of death or to a minimum of 5 years after femoral outflow reconstruction was performed. Only four pa...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1984-04-01 00:00:00
abstract：BACKGROUND:Lung injury is a life-threatening complication in patients with liver dysfunction. We recently provided an experimental lung injury model in mouse with common bile duct ligation. In this study, we aimed to characterize the pathologic and biochemical features of lung tissues in common bile duct ligation mice ...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2016.12.017
更新日期：2017-06-01 00:00:00
abstract：:A protein kinase activity completely dependent on Mn2+ was studied in the cytosolic fraction from rabbit-isolated gastric glands. The manganese-dependent protein kinase (MNPK) activity phosphorylated major 33 kd (pp33) and minor 140 kd (pp140) endogenous proteins. The MNPK activity displayed a Kact for Mn2+ of 7.5 mmo...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1986-08-01 00:00:00
abstract：:Rats, with their liver DNA labeled with 3H-thymidine, were subjected to hemorrhagic shock. In nine rats reversible hemorrhagic shock with a blood pressure of 40 mm Hg for 30 minutes resulted in no breaks in the DNA. Twenty-seven animals were subjected to severe hemorrhagic shock. Blood pressures of 40 mm Hg were maint...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1979-03-01 00:00:00
abstract：:To reevaluate the validity of our policy of mandatory surgical exploration of penetrating zone II neck injuries, the charts of 110 patients who underwent surgical exploration for such injuries were reviewed. Fifty-three percent of the patients had normal findings at exploration, whereas 33% had injuries involving vasc...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1986-10-01 00:00:00
abstract：:Because high calcium concentration in vitro stimulates muscle proteolysis, calcium has been implicated in the pathogenesis of increased muscle breakdown in different catabolic conditions. Protein breakdown in skeletal muscle is increased during sepsis, but the effect of sepsis on muscle calcium uptake and content is n...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1989-07-01 00:00:00
abstract：BACKGROUND:The most common cause of noncurative resection and recurrence is gastric cancer is peritoneal seeding. However, the results of treatment of peritoneal dissemination with chemotherapy have been poor with 5-year survival rates of 0%. METHODS:A new in vitro thermochemosensitivity test was performed on gastric ...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/s0039-6060(96)80145-0
更新日期：1996-04-01 00:00:00
abstract：BACKGROUND:Carcinoid tumors of the duodenum are rare, and their natural history has not been defined. Consequently, there is no consensus on the optimal extent of surgical treatment. METHODS:The authors reviewed the records of all patients with primary carcinoid tumors of the duodenum treated at their institution from...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2005.09.016
更新日期：2005-12-01 00:00:00
abstract：BACKGROUND:Misdiagnosed primary hyperparathyroidism (PHPT) during thyroid surgery may lead to a difficult reoperation. Because PHPT is often asymptomatic, calcium measurements have been recommended before thyroid surgery, but no study has focused on the results of a prospective PHPT screening. METHODS:The prospective ...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1067/msy.2002.121379
更新日期：2002-03-01 00:00:00
abstract：BACKGROUND:The carcinogenic effect of duodenoesophageal reflux, gastroesophageal reflux, and nitrosamines was studied in the rat esophagus. METHODS:Twenty male Sprague-Dawley rats underwent esophagogastroplasty to produce gastroesophageal reflux and 60 underwent duodenoesophageal anastomosis to produce duodenoesophage...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1992-05-01 00:00:00
abstract：:Earlier work has shown that morphine sulfate can produce a dose-related decrease in heart rate (HR) and cardiac output (CO) in isolated working rat hearts. This response is preventable with the use of the opiate receptor antagonist, naloxone hydrochloride. In this study, the stereospecificity of the opiate response wa...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1987-08-01 00:00:00
abstract：:Forty-five patients with varying biliary pathology were injected with one gram of intramuscular cefazolin sodium prior to surgery. Serum, gallbladder bile, and common duct bile levels were measured. The type of biliary disease did not influence serum levels (mean, 29 mug per milliliter) which reached a peak one hour a...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1977-04-01 00:00:00
abstract：:The blood lost through the suture line holes of vessels closed with braided polyester sutures is compared with that lost when a monofilament polypropylene suture is employed. In a retrospective analysis of blood replacement during saphenous vein aortorenal bypasses, twice as much blood replacement was required when th...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1975-08-01 00:00:00
abstract：BACKGROUND:General, health-related quality-of-life questionnaires and recovery-specific questionnaires have been used to measure recovery in surgical patients. The aim of this study was to evaluate the clinimetric properties of 3 recovery instruments and to examine whether recovery-specific instruments are useful. MET...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2008.03.027
更新日期：2008-07-01 00:00:00
abstract：BACKGROUND:A better understanding of the analgesia needs of patients who undergo common operative procedures is necessary as we address the growing opioid public health crisis in the United States. The aim of this study was to evaluate patient experience with our opioid prescribing practice after elective inguinal hern...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2017.06.017
更新日期：2017-11-01 00:00:00
abstract：BACKGROUND:Although the effect of preoperative biliary drainage in patients with obstructive jaundice is controversial, bacterial or endotoxin translocation is one of the main postoperative problem in jaundiced patients. Failure in gut barrier functions causes bacterial translocation; homing and distribution of T lymph...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2004.02.001
更新日期：2004-09-01 00:00:00
abstract：BACKGROUND:Although prophylactic glucocorticoids have been used before liver resection to minimize liver dysfunction, it is unknown whether treatment with glucocorticoids will accelerates recovery from hyperbilirubinemia after liver resection. METHODS:In this open-label, randomized, controlled trial, patients with hyp...
journal_title：Surgery
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.surg.2018.09.002
更新日期：2019-03-01 00:00:00
abstract：BACKGROUND:The clinical importance of point mutations of ras oncogene in differentiated thyroid cancers has not been fully clarified. The purpose of this study is to determine the prognostic importance of ras mutation in papillary thyroid carcinoma. METHODS:Tumors of 91 patients with papillary carcinoma were studied; ...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1994-12-01 00:00:00
abstract：:A case report of a girl with anomalous venous drainage of a lower extremity who had a successful venous transplant is presented, along with a review of some factors thought to be important in venous grafting. In our patient there are several factors that may have contributed to long-term patency. As demonstrated by ve...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1978-05-01 00:00:00
abstract：BACKGROUND:Cholecystosteatosis is the accumulation of gallbladder wall fats leading to decreased gallbladder emptying. Ezetimibe inhibits intestinal fat absorption and prevents murine gallstone formation. However, the influence of ezetimibe on gallbladder emptying and cholecystosteatosis has not been studied. Therefore...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2007.04.007
更新日期：2007-08-01 00:00:00
abstract：:The left renal vein (LRV) has numerous tributaries including, but not limited to, the inferior phrenic, suprarenal, and gonadal veins. The resultant potential for collateral LRV outflow through these tributaries in instances of LRV division is obvious. One of us has previously reported 10 such cases of LRV division (c...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
abstract：BACKGROUND:Complex anal fistulas are unsuitable for fistulotomy because of the risk of fecal incontinence. The anal fistula plug (AFP) has demonstrated fistula healing without sphincter division. This study aims to evaluate the cost-effectiveness of the AFP compared to the endoanal advancement flap (EAAF) as an alterna...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2009.05.018
更新日期：2010-01-01 00:00:00
abstract：:Heterotopic rat heart allografts were performed in 35 rats. At intervals after transplantation, rats were killed and tissue concentrations of immunoassayable prostaglandin E (PGE) were measured in the native heart, transplanted heart, spleen, and thymus. A significant increase in allograft PGE activity was observed at...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1975-10-01 00:00:00
abstract：:The quantitative effects of cytomegalovirus (CMV) infection on morbidity and mortality rates were examined in 320 renal transplant cases. With the use of virus cultures and CMV antibody measurements, all patients were studied, regardless of symptoms, from a time before transplantation to at least 1 year, 11 months aft...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1981-06-01 00:00:00
abstract：BACKGROUND:Hypoglycemia after resection of pheochromocytoma is a rare and poorly understood complication thought to be secondary to rebound hyperinsulinemia and increased peripheral glucose uptake. We examined the incidence of this complication and aimed to identify predisposing risk factors. METHODS:Patients who unde...
journal_title：Surgery
pub_type： 杂志文章,多中心研究
doi：10.1016/j.surg.2014.08.020
更新日期：2014-12-01 00:00:00
abstract：BACKGROUND:Mortality after acute respiratory distress syndrome is higher in males than in females. Gender differences in pulmonary vascular reactivity and local inflammatory response may explain this disparity. We hypothesized that endothelium-dependent pulmonary vasorelaxation is impaired in males and that this effect...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2005.03.002
更新日期：2005-07-01 00:00:00
abstract：BACKGROUND:In a dynamic health care system, strong leadership has never been more important for surgeons. Little is known about how to design and conduct effectively a leadership program specifically for surgeons. We sought to evaluate critically a Leadership Development Program for practicing surgeons by exploring how...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2016.03.011
更新日期：2016-08-01 00:00:00
abstract：INTRODUCTION:Tertiary hyperparathyroidism (3HPTH) patients who undergo parathyroidectomy (PTX) are often managed with calcium lowering medications such as cinacalcet (Sensipar) before surgery. Here, we assess how cinacalcet treatment influences intraoperative parathyroid hormone (IOPTH) kinetics and surgical findings i...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2014.08.003
更新日期：2014-12-01 00:00:00
abstract：:In a prospective study the accuracy of B-mode ultrasound imaging alone was compared with its use in conjunction with bidirectional Doppler ultrasound, carotid phonoangiography, and oculoplethysmography to independently assess contrast arteriograms of carotid arteries studied for presumed extracranial vascular disease....
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1983-01-01 00:00:00
abstract：BACKGROUND:In the evaluation of patients with primary hyperparathyroidism (PHP), specific query for a personal or family history of MEN1 (Hx) is recommended widely, but responses are rarely positiv. We instituted a 6-question panel (6Q) to routinely screen for MEN1 preoperatively. METHODS:The clinical database entries...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2008.07.030
更新日期：2008-12-01 00:00:00
