Abstract:
BACKGROUND:Hypoglycemia after resection of pheochromocytoma is a rare and poorly understood complication thought to be secondary to rebound hyperinsulinemia and increased peripheral glucose uptake. We examined the incidence of this complication and aimed to identify predisposing risk factors. METHODS:Patients who underwent pheochromocytoma resection between 1993 and 2013 at 2 large academic medical centers were identified retrospectively from a research patient data registry. The primary end point was postoperative hypoglycemia defined as blood glucose <55 mg/dL. RESULTS:A total of 213 patients underwent resection of pheochromocytoma for a total of 215 operations. Nine patients (4.2%) experienced postoperative hypoglycemia, with 8 of 9 episodes occurring in the first 24 hours. Patients who developed hypoglycemia were more likely to have greater preoperative 24-hour urinary metanephrine (4,726 vs 2,461 μg/24 h, P = .05) and experienced longer operative times (270 vs 142 minutes, P < .01) with larger neoplasms (7.6 vs 4.6 cm, P = .02). Postoperatively, patients with hypoglycemia required intensive care level monitoring more frequently (88.9% vs 34.5%, P < .01), but there was no difference in duration of hospital stay (5 vs 3 days, P = .10). CONCLUSION:Our data demonstrate that hypoglycemia is a rare complication after resection of pheochromocytoma and may be more common in patients with epinephrine-predominant neoplasms and longer operative times.
journal_name
Surgeryjournal_title
Surgeryauthors
Chen Y,Hodin RA,Pandolfi C,Ruan DT,McKenzie TJdoi
10.1016/j.surg.2014.08.020subject
Has Abstractpub_date
2014-12-01 00:00:00pages
1404-8; discussion 1408-9issue
6eissn
0039-6060issn
1532-7361pii
S0039-6060(14)00498-Xjournal_volume
156pub_type
杂志文章,多中心研究相关文献
SURGERY文献大全abstract::Heroism among military physicians has been heralded throughout our history. Four Navy trauma surgeons who received the Navy Cross for extraordinary service during the Vietnam War were studied with reference to their early lives, the events leading to the act for which they received the Navy Cross, and their later live...
journal_title:Surgery
pub_type: 传,历史文章,杂志文章
doi:
更新日期:1991-11-01 00:00:00
abstract:BACKGROUND:Many breast cancer patients and survivors experience clinically significant distress, which poses a danger to both their psychologic and clinical well-being. Improved understanding of the types of distress that patients experience at the time of breast cancer diagnosis may reveal areas for intervention to im...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2020.04.051
更新日期:2020-11-01 00:00:00
abstract::Serious complications of local venous hypertension occur rarely in the upper extremity. These are most frequently the result of a dysfunctional arteriovenous fistula and may produce changes indistinguishable from those of chronic lower-extremity venous insufficiency. A combination of arterial and venous contrast imagi...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1985-09-01 00:00:00
abstract:BACKGROUND:Because of controversy about the correct treatment of toxic solitary thyroid nodules, we reviewed our experience. METHODS:We retrospectively studied 32 patients (24 women and 8 men) with solitary toxic thyroid nodules who were treated at our institution (1970 to 1985). RESULTS:Median values were as follows...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1992-12-01 00:00:00
abstract:BACKGROUND:Discrimination of malignant proximal bile duct (PBD) stricture from a benign lesion is difficult with nonsurgical methods; indeed, 8% to 13% of PBD strictures prove to be benign after histologic examination of the surgically resected specimen. METHODS:In a 7-year period 178 patients with PBD stricture were ...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1999-05-01 00:00:00
abstract::To determine the relative value of carotid phonoangiography (CPA), oculoplethysmography-Kartchner (OPG-K), and Doppler ultrasonic arteriography (UA), 90 vessels undergoing carotid endarterectomy were prospectively examined. By analyzing the data on receiver operator characteristic curves, the dynamic relationship betw...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1980-01-01 00:00:00
abstract::In 337 limbs (208 patients) with primary varicose veins, Doppler ultrasound was used to detect reverse flow in the saphenous veins caused by manual compression of the calf. According to the extent of reverse flow in the saphenous trunks, varicosities of the long saphenous vein were classified into five types and the s...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1988-06-01 00:00:00
abstract::Myocardial high-energy phosphate and glucose-6-phosphate levels were determined in the in vivo pig heart model during ischemic arrest and reperfusion to determine the effectiveness of potassium cardioplegia in myocardial protection. Thirty-five pigs were divided into six experimental groups consisting of 2-hour normot...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1979-07-01 00:00:00
abstract:INTRODUCTION:Systemic hyperfibrinolysis (accelerated clot degradation) and fibrinolysis shutdown (impaired clot degradation) are associated with increased mortality compared with physiologic fibrinolysis after trauma. Animal models have not reproduced these changes. We hypothesize rodents have a shutdown phenotype that...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2015.04.008
更新日期:2015-08-01 00:00:00
abstract:BACKGROUND:Ischemia and reperfusion (I/R) injury is a major determinant of early graft dysfunction and long-term graft survival in small intestinal transplantation. The cavitary two-layer method (TLM) has been reported to be superior to the University of Wisconsin cold storage method (UWM) in long-term preservation of ...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2003.10.013
更新日期:2004-06-01 00:00:00
abstract:BACKGROUND:Thoracopancreatic fistula is a rare clinical entity but a serious complication of inflammatory pancreatic diseases, caused by a disruption of the pancreatic ductal system. Its diagnosis is frequently misleading, however, and thus is often delayed. METHODS:Seven patients with thoracopancreatic fistula who pr...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2006.02.020
更新日期:2006-11-01 00:00:00
abstract:BACKGROUND:Corticosteroid use continues to rise nationally. Studies have evaluated the impact of chronic steroid use on surgical outcomes in smaller populations. This study investigated the impact of chronic steroid use on perioperative surgical outcomes in a surgical cohort of more than 5 million surgical patients, us...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2018.12.016
更新日期:2019-05-01 00:00:00
abstract:BACKGROUND:Pelvic ring fractures (PRFs) are a major cause of morbidity and mortality in motor vehicle collisions (MVCs). Understanding the factors leading to PRFs may help improve vehicle design and safety. This study sought to determine the vehicular, crash, and occupant characteristics that contribute to PRFs. METHO...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2004.07.003
更新日期:2004-10-01 00:00:00
abstract::We studied the effect of the topical application of the nonsteroidal anti-inflammatory agent, flurbiprofen, on postburn hypermetabolism and systemic lipid peroxidation. Twelve sheep with a 15% total body surface third-degree burn were monitored over a 4-day postburn period. In six sheep, a single application of a 5% f...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1991-05-01 00:00:00
abstract:BACKGROUND:The hypermetabolic response to severe burn is characterized by muscle protein catabolism. Current opinion states that the hypermetabolic state resolves soon after complete wound closure. Clinically, we have witnessed that burned children appear to be hypermetabolic and catabolic long after full healing of th...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1067/msy.2000.108059
更新日期:2000-08-01 00:00:00
abstract::DNA content has been reported to be of prognostic significance in differentiated thyroid carcinoma. Since malignant tumors with irradiation as an initiator often contain DNA aberrations, the DNA content of well-differentiated thyroid carcinoma in patients with a prior history of low-dose head and neck irradiation was ...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1988-12-01 00:00:00
abstract::Unlike its lethal exocrine counterpart, islet cell carcinoma of the pancreas is an indolent neuroendocrine neoplasm. The majority of these tumors are hormonally active. When functioning, a number of clinical syndromes (for example, hyperinsulinism, Zollinger-Ellison and Cushing's syndromes) may be evident. Fifty-eight...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1988-12-01 00:00:00
abstract:BACKGROUND:A pathologic complete response (pCR) can be observed in up to 25% of patients after preoperative chemoradiotherapy for rectal cancer and is associated with an improved long-term prognosis. However, few data are available regarding the effect of pCR on postoperative morbidity. This study aimed to assess the i...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2013.10.020
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND:Failure to achieve primary fascial closure (PFC) after damage control laparotomy is costly and carries great morbidity. We hypothesized that time from the initial laparotomy to the first take-back operation would be predictive of successful PFC. METHODS:Trauma patients managed with open abdominal techniques...
journal_title:Surgery
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1016/j.surg.2014.04.019
更新日期:2014-08-01 00:00:00
abstract::A report of a 38-year-old man with a 10 month course of illness characterized by recurrent pericardial and pleural high-protein, high-amylase effusions is presented. Operative pancreatogram demonstrated fistulization from the mid-pancreas through the mediastinum into both pleural spaces and the pericardium. Surgical d...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1979-04-01 00:00:00
abstract::An occlusion of the superior vena cava by a tumor thrombus extending into the right atrium was diagnosed in three patients with a follicular thyroid cancer. All patients showed the typical clinical picture of the superior vena cava syndrome. A right parasternal thoracotomy was performed for preparation of the major ve...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1990-12-01 00:00:00
abstract::A 20-year-old man underwent a 9-hour operation in a left lateral position for the removal of an osteoblastoma involving the pedicles of thoracic vertebrae T-11 and T-12 and for fixation with bond grafting. Immediately after the operation, extensive swelling of the left shoulder area was noted. The radial pulse on the ...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1989-03-01 00:00:00
abstract::This study examines the effect of pretreatment with 10(8) ultraviolet B-irradiated donor leukocytes (UV-DL) with or without peritransplant cyclosporine (CyA) treatment (20 mg/kg on days 0, +1, and +2 relative to transplantation) on rat cardiac allograft survival across major histocompatibility loci. A single UV-DL pre...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1988-08-01 00:00:00
abstract:BACKGROUND:Posttransplantation diabetes mellitus (PTDM), a common complication of current immunosuppressive regimens, has been attributed to the diabetogenic effects of prednisone and cyclosporine. We report our experience with steroid withdrawal (SW) in renal allograft recipients with PTDM. METHODS:SW was attempted o...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1994-10-01 00:00:00
abstract:BACKGROUND:Vocal cord paralysis is associated with extrathyroidal invasive malignancy. This study was performed to analyze the presentation of patients with invasive thyroid malignancy and to determine the preoperative symptomatic and radiographic correlates of vocal cord paralysis. METHODS:In a group of 365 consecuti...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2005.08.009
更新日期:2006-03-01 00:00:00
abstract:BACKGROUND:Preoperative noninvasive localization studies of the neck and mediastinum are beneficial before reoperation. However, the role of selective venous sampling (SVS) for parathyroid hormone (PTH) in reoperative parathyroid surgery has never been clearly defined. The purpose of this study was to evaluate the accu...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1067/msy.2002.128477
更新日期:2002-12-01 00:00:00
abstract::This study compares the National Board of Medical Examiners Part II (NBME II) subtest scores of medical students attaining honors in a clinical clerkship to those of students receiving a passing score to determine if the NBME II examinations could be considered independently as valid indicators of clinical achievement...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1981-06-01 00:00:00
abstract:BACKGROUND:Plasma peptide YY (PYY) levels rise after a meal and have recently been shown to increase small bowel-absorption. The purpose of this study was to determine whether immunoneutralization of PYY would block postprandial absorption in vivo. METHODS:Exteriorized, neurovascularly intact jejunal and ileal segment...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1994-12-01 00:00:00
abstract:BACKGROUND:Nodal status is one of the most important prognostic factors for carcinoma of the papilla of Vater. The pattern of lymphatic spread and mode of recurrence were analyzed by determining the frequency of nodal involvement and antemortem and postmortem examination of patients with recurrent disease. METHODS:Fro...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/s0039-6060(97)90048-9
更新日期:1997-06-01 00:00:00
abstract:BACKGROUND:Surgical management of patients with metastatic or recurrent rectal cancer remains controversial. Self-expanding metal stents are increasingly used for palliative treatment of advanced tumors, although long-term results are not yet available. METHODS:Between 1996 and 2003, 521 patients underwent surgery for...
journal_title:Surgery
pub_type: 临床试验,杂志文章
doi:10.1016/j.surg.2004.05.043
更新日期:2005-01-01 00:00:00