Amino acid abnormalities in cerebrospinal fluid of patients with parkinsonism and extrapyramidal disorders.

abstract：BACKGROUND:Most cavernous sinus dural arteriovenous malformations (CSdAVM) have a benign clinical course. Those CSdAVM that drain into cortical veins have an increased risk for neurologic complications. OBJECTIVE:To find whether a specific clinical sign predicts cortical venous drainage (CVD) in CSdAVM. METHODS:The r...

journal_title：Neurology

authors： Stiebel-Kalish H,Setton A,Berenstein A,Kalish Y,Nimii Y,Kupersmith MJ

更新日期：2002-05-28 00:00:00

abstract：OBJECTIVE:To investigate the sensitivity of MRI of the spine compared with CT myelography (CTM) in detecting CSF leaks. METHODS:Between July 1998 and October 2010, 12 patients with orthostatic headache and a CTM-confirmed spinal CSF leak underwent an MRI of the spine with and without contrast. Using CTM as the gold st...

journal_title：Neurology

authors： Starling A,Hernandez F,Hoxworth JM,Trentman T,Halker R,Vargas BB,Hastriter E,Dodick D

更新日期：2013-11-12 00:00:00

abstract：OBJECTIVE:To determine the rate of relapse occurrence during pregnancy and postpartum. METHODS:In a cross-sectional study using the national multiple sclerosis (MS) registry, pregnant women with relapsing MS were identified. Data on demographics, clinical characteristics, and disease-modifying therapies (DMTs), includ...

journal_title：Neurology

authors： Alroughani R,Alowayesh MS,Ahmed SF,Behbehani R,Al-Hashel J

更新日期：2018-03-06 00:00:00

abstract：OBJECTIVE:To evaluate relationships among cognitive, behavioral, and psychiatric/psychosocial measures assessed in a multicenter cohort of patients with amyotrophic lateral sclerosis (ALS). METHODS:Recently diagnosed patients with definite or probable ALS diagnosis were administered 7 standardized psychiatric/psychoso...

journal_title：Neurology

authors： Rabkin J,Goetz R,Murphy JM,Factor-Litvak P,Mitsumoto H,ALS COSMOS Study Group.

更新日期：2016-09-27 00:00:00

abstract：OBJECTIVE:To assess the predominant type of cerebral small vessel disease (SVD) and recurrence risk in patients who present with a combination of lobar and deep intracerebral hemorrhage (ICH)/microbleed locations (mixed ICH). METHODS:Of 391 consecutive patients with primary ICH enrolled in a prospective registry, 75 (...

journal_title：Neurology

authors： Pasi M,Charidimou A,Boulouis G,Auriel E,Ayres A,Schwab KM,Goldstein JN,Rosand J,Viswanathan A,Pantoni L,Greenberg SM,Gurol ME

更新日期：2018-01-09 00:00:00

abstract：:We detected large numbers of HLA-DR-positive reactive microglia (macrophages), along with Lewy bodies and free melanin, in the substantia nigra of all cases studied with Parkinson's disease (5) and parkinsonism with dementia (PD) (5). We found similar, but less extensive, pathology in the substantia nigra of six of ni...

journal_title：Neurology

authors： McGeer PL,Itagaki S,Boyes BE,McGeer EG

更新日期：1988-08-01 00:00:00

abstract：:Many studies of monozygotic (MZ) twins have revealed evidence of genetic influences on intellectual functions and their derangement in certain neurologic and psychiatric diseases afflicting the forebrain. Relatively little is known about genetic influences on the size and shape of the human forebrain and its gross mor...

journal_title：Neurology

authors： Tramo MJ,Loftus WC,Stukel TA,Green RL,Weaver JB,Gazzaniga MS

更新日期：1998-05-01 00:00:00

abstract：:Two adult brothers became ill within 48 hours of each other, and both had severe myoglobinuria. One brother died of oliguric renal failure. The other did not have renal failure and survived. Acute influenza A infection was documented serologically and from throat washings in the surviving brother, and by isolation of ...

journal_title：Neurology

authors： Zamkoff K,Rosen N

更新日期：1979-03-01 00:00:00

abstract：:The authors interviewed 53 cluster headache patients who had used psilocybin or lysergic acid diethylamide (LSD) to treat their condition. Twenty-two of 26 psilocybin users reported that psilocybin aborted attacks; 25 of 48 psilocybin users and 7 of 8 LSD users reported cluster period termination; 18 of 19 psilocybin ...

journal_title：Neurology

authors： Sewell RA,Halpern JH,Pope HG Jr

更新日期：2006-06-27 00:00:00

abstract：OBJECTIVE:To evaluate topiramate as monotherapy in adults and children with recently diagnosed, localization-related epilepsy, comparing two dosages of topiramate in a multicenter, randomized, double-blind study. METHODS:Adults and children (>/=3 years of age) were eligible if the maximum interval since epilepsy diagn...

journal_title：Neurology

authors： Gilliam FG,Veloso F,Bomhof MA,Gazda SK,Biton V,Ter Bruggen JP,Neto W,Bailey C,Pledger G,Wu SC

更新日期：2003-01-28 00:00:00

abstract：OBJECTIVE:We conducted a nationwide case-control study in Sweden to test the hypothesis that specific clinical characteristics are associated with increased risk of sudden unexpected death in epilepsy (SUDEP). METHODS:The study included 255 SUDEP cases (definite and probable) and 1,148 matched controls. Clinical infor...

journal_title：Neurology

authors： Sveinsson O,Andersson T,Mattsson P,Carlsson S,Tomson T

更新日期：2020-01-28 00:00:00

abstract：OBJECTIVE:To determine the latency, magnitude, and duration of the long-duration response (LDR) to levodopa in PD in relationship to the administration of levodopa at different interdose intervals. METHODS:In six patients with PD, two different 15-day treatment regimens were used in which the drug was administered wit...

journal_title：Neurology

authors： Zappia M,Bosco D,Plastino M,Nicoletti G,Branca D,Oliveri RL,Aguglia U,Gambardella A,Quattrone A

更新日期：1999-08-11 00:00:00

abstract：:We identified 53 patients with non-neoplastic cysts of the pineal gland. In contrast to patients with pineal neoplasms, pineal cysts are usually asymptomatic. They infrequently obstruct the aqueduct to cause hydrocephalus or compress the tectum to produce the neuro-ophthalmologic signs of dorsal midbrain dysfunction. ...

journal_title：Neurology

authors： Fetell MR,Bruce JN,Burke AM,Cross DT,Torres RA,Powers JM,Stein BM

更新日期：1991-07-01 00:00:00

abstract：:We performed magnetic resonance imaging (MRI), before and after the administration of gadolinium-DTPA (Gd-DTPA), in 23 patients with medically refractory partial epilepsy who subsequently had surgical treatment for their seizure disorder. In most patients, 61%, unenhanced and enhanced MRI studies were negative. In 26%...

journal_title：Neurology

authors： Cascino GD,Hirschorn KA,Jack CR,Sharbrough FW

更新日期：1989-08-01 00:00:00

abstract：BACKGROUND:Patients with Alzheimer's disease (AD) and many older adults become lost even in familiar surroundings. This is commonly attributed to memory impairment, but it may reflect impaired spatial cognition. METHODS:The authors examined the role of memory, perceptual, and cognitive mechanisms in spatial disorienta...

journal_title：Neurology

authors： Monacelli AM,Cushman LA,Kavcic V,Duffy CJ

更新日期：2003-12-09 00:00:00

abstract：OBJECTIVE:To study prevalence of and factors contributing to burnout, career satisfaction, and well-being in US neurology residents and fellows. METHODS:A total of 938 US American Academy of Neurology member neurology residents and fellows were surveyed using standardized measures of burnout, career satisfaction, and ...

journal_title：Neurology

authors： Levin KH,Shanafelt TD,Keran CM,Busis NA,Foster LA,Molano JRV,O'Donovan CA,Ratliff JB,Schwarz HB,Sloan JA,Cascino TL

更新日期：2017-08-01 00:00:00

abstract：:Effective diagnosis and treatment of cytomegalovirus infection of the nervous system in AIDS patients has been limited by a lack of sensitive diagnostic measures. Retrospective series suggest a poor prognosis for cytomegalovirus encephalitis with rapid mortality. Polymerase chain reaction amplification of cytomegalovi...

journal_title：Neurology

authors： Cohen BA

更新日期：1996-02-01 00:00:00

abstract：:The authors retrospectively reviewed the efficacy of mycophenolate mofetil (MMF; mean dose, 2 g/day given for an average of 14 months) in 21 patients with immune demyelinating polyneuropathy. There were no significant differences in the median strength, sensory, or Rankin scores before and after treatment. In patients...

journal_title：Neurology

authors： Gorson KC,Amato AA,Ropper AH

更新日期：2004-08-24 00:00:00

abstract：OBJECTIVE:To investigate long-term employment outcomes after resective epilepsy surgery in a national population-based cohort of adults. METHODS:In the Swedish National Epilepsy Surgery Register, all adults who were operated with resective epilepsy surgery from 1995 to 2010 were identified. Two-year follow-up was avai...

journal_title：Neurology

authors： Edelvik A,Flink R,Malmgren K

更新日期：2015-10-27 00:00:00

abstract：BACKGROUND:Hereditary neuralgic amyotrophy (HNA) is an autosomal-dominant disorder associated with recurrent, episodic, painful, brachial neuropathy. The gene for HNA has been mapped to chromosome 17q25. Characteristic features including hypotelorism, short stature, and cleft palate occur in some patients. OBJECTIVE:T...

journal_title：Neurology

authors： Jeannet PY,Watts GD,Bird TD,Chance PF

更新日期：2001-12-11 00:00:00

abstract：:A veterinarian contracted rabies in the course of laboratory work with homogenates of rabid goat brain. Epidemiologic study determined a respiratory mode of transmission. After a fulminant encephalitic illness, formed rabies virions were identified in the synaptic zones of the olfactory glomeruli. Identification, isol...

journal_title：Neurology

authors： Conomy JP,Leibovitz A,McCombs W,Stinson J

更新日期：1977-01-01 00:00:00

abstract：OBJECTIVE:We determined whether Gram-negative bacterial molecules are associated with Alzheimer disease (AD) neuropathology given that previous studies demonstrate Gram-negative Escherichia coli bacteria can form extracellular amyloid and Gram-negative bacteria have been reported as the predominant bacteria found in no...

journal_title：Neurology

authors： Zhan X,Stamova B,Jin LW,DeCarli C,Phinney B,Sharp FR

更新日期：2016-11-29 00:00:00

abstract：OBJECTIVES:To evaluate the frequency, clinical and etiologic features, and short- and long-term outcomes of early recurrent TIA. METHODS:This prospective observational cohort study enrolled all consecutive patients with TIA referred to our emergency department and diagnosed by a vascular neurologist. Expedited assessm...

journal_title：Neurology

authors： Foschi M,Pavolucci L,Rondelli F,Spinardi L,Favaretto E,Filippini M,Degli Esposti D,Strocchi E,Faggioli G,Cortelli P,Guarino M,Bologna TIA Study-Group.

更新日期：2020-09-22 00:00:00

abstract：OBJECTIVES:To identify gene mutations in patients with dystroglycanopathy and prove pathogenicity of those mutations using an in vitro cell assay. METHODS:We performed whole-exome sequencing on 20 patients, who were previously diagnosed with dystroglycanopathy by immunohistochemistry and/or Western blot analysis. We a...

journal_title：Neurology

authors： Dong M,Noguchi S,Endo Y,Hayashi YK,Yoshida S,Nonaka I,Nishino I

更新日期：2015-01-20 00:00:00

abstract：:We investigated the modulatory effects of human interferon beta (IFN-beta) and gamma (IFN-gamma) on expression of class I and II major histocompatibility complex (MHC) antigens and intercellular adhesion molecule-1 (ICAM-1) in fetal human astrocytes in culture using flow cytometry and immunocytochemistry. Under the ba...

journal_title：Neurology

authors： Satoh J,Paty DW,Kim SU

更新日期：1995-02-01 00:00:00

abstract：:Status epilepticus occurs in more than 50,000 people in the United States each year and should be considered a neurologic emergency. A variety of drugs are used to treat status epilepticus, including i.v. benzodiazepines, phenytoin, and barbiturates. They are all short of being ideal, primarily because of difficulties...

journal_title：Neurology

authors： Runge JW,Allen FH

更新日期：1996-06-01 00:00:00

abstract：OBJECTIVE:Autonomic symptoms may occur frequently in diabetic and other neuropathies. There is a need to develop a simple instrument to measure autonomic symptoms in subjects with neuropathy and to test the validity of the instrument. METHODS:The Survey of Autonomic Symptoms (SAS) consists of 11 items in women and 12 ...

journal_title：Neurology

authors： Zilliox L,Peltier AC,Wren PA,Anderson A,Smith AG,Singleton JR,Feldman EL,Alexander NB,Russell JW

更新日期：2011-03-22 00:00:00

abstract：OBJECTIVE:To describe two symptomatic dysferlin gene mutation carriers. METHODS:One patient had limb girdle weakness. His brother was diagnosed with limb girdle muscular dystrophy 2B with two mutations in the dysferlin gene (D625Y and E1734G). The second patient had distal weakness. He had two sons with Miyoshi myopat...

journal_title：Neurology

authors： Illa I,De Luna N,Domínguez-Perles R,Rojas-García R,Paradas C,Palmer J,Márquez C,Gallano P,Gallardo E

更新日期：2007-04-17 00:00:00

abstract：:Significant evidence has accrued suggesting that antibodies to voltage-gated calcium channel are observed in at least some patients with sporadic ALS (SALS) and that such antibodies alter the function of these ion channels in vitro and in vivo. Further, passive transfer of these immunoglobulin-containing fractions int...

journal_title：Neurology

authors： Smith RG,Siklos L,Alexianu ME,Engelhardt JI,Mosier DR,Colom L,Habib Mohamed A,Appel SH

更新日期：1996-10-01 00:00:00

abstract：:We analyzed ictal features of psychogenic seizures using video-EEG recordings in 47 patients and reviewed the medical records to determine if patients received antiepileptic drug therapy and whether they were treated pharmacologically for status epilepticus. Unresponsive behavior in the absence of motor manifestations...

journal_title：Neurology

authors： Leis AA,Ross MA,Summers AK

更新日期：1992-01-01 00:00:00