Human papillomavirus type 11 recombinant L1 capsomeres induce virus-neutralizing antibodies.

abstract：:The E7 oncoprotein of human papillomavirus 16 (HPV16) transforms basal and suprabasal cervical epithelial cells and is a tumor-specific antigen in cervical carcinoma, to which immunotherapeutic strategies aimed at cytotoxic T-lymphocyte (CTL) induction are currently directed. By quantifying major histocompatibility co...

journal_title：Journal of virology

authors： Tindle RW,Herd K,Doan T,Bryson G,Leggatt GR,Lambert P,Frazer IH,Street M

更新日期：2001-07-01 00:00:00

abstract：:Some strains of the protozoan parasite genus Leishmania are persistently infected with single-segmented double-stranded RNA viruses, which are termed LRV. The function of these cytoplasmic viruses is unknown. In order to address the question of whether LRV affects the parasite's phenotype, pairs of isogenic LRV(+)-LRV...

journal_title：Journal of virology

authors： Widmer G

更新日期：1995-07-01 00:00:00

abstract：:Polyomaviruses are small nonenveloped particles with a circular double-stranded genome, approximately 5 kbp in size. The mammalian polyomaviruses mainly cause persistent subclinical infections in their natural nonimmunocompromised hosts. In contrast, the polyomaviruses of birds--avian polyomavirus (APV) and goose hemo...

journal_title：Journal of virology

authors： Johne R,Wittig W,Fernández-de-Luco D,Höfle U,Müller H

更新日期：2006-04-01 00:00:00

abstract：:Vesicular stomatitis virus (VSV) has been shown in laboratory studies to be effective against a variety of tumors, including malignant brain tumors. However, attenuation of VSV may be necessary to balance the potential toxicity toward normal cells, particularly when targeting brain tumors. Here we compared 10 recombin...

journal_title：Journal of virology

authors： Wollmann G,Rogulin V,Simon I,Rose JK,van den Pol AN

更新日期：2010-02-01 00:00:00

abstract：:White spot syndrome virus (WSSV) occurs worldwide and causes high mortality and considerable economic damage to the shrimp farming industry. No adequate treatments against this virus are available. It is generally accepted that invertebrates such as shrimp do not have an adaptive immune response system such as that pr...

journal_title：Journal of virology

authors： Witteveldt J,Cifuentes CC,Vlak JM,van Hulten MC

更新日期：2004-02-01 00:00:00

abstract：:A number of avocado (Persea americana) cultivars are known to contain high-molecular-weight double-stranded RNA (dsRNA) molecules for which a viral nature has been suggested, although sequence data are not available. Here we report the cloning and complete sequencing of a 13.5-kbp dsRNA virus isolated from avocado and...

journal_title：Journal of virology

authors： Villanueva F,Sabanadzovic S,Valverde RA,Navas-Castillo J

更新日期：2012-01-01 00:00:00

abstract：:A phage, designated CP-51, that carries out generalized transduction in Bacillus cereus 569 was isolated from soil. All auxotrophic mutants tested, those requiring tryptophan, histidine, leucine, isoleucine, methionine, or phenylalanine, were transduced to prototrophy. The phage was extremely unstable when stored at 2...

journal_title：Journal of virology

authors： Thorne CB

更新日期：1968-07-01 00:00:00

abstract：:Inbred LSH hamster brain cells were transformed in vitro by the GS strain of BK virus (BKV), and transplantable tumors classified as undifferentiated glioblastomas were induced in the syngeneic host. The viral status in the transformed cells, designated LSH-BR-BK, was established. About 46 genome equivalents per cell ...

journal_title：Journal of virology

authors： Beth E,Giraldo G,Schmidt-Ullrich R,Pater MM,Pater A,di Mayorca G

更新日期：1981-10-01 00:00:00

abstract：:Retroviruses have been isolated from the tissues of human leukemia patients. Previous studies have shown that these isolates share some antigenic determinants with the family of viruses isolated from the woolly monkey and gibbon ape and that they exhibit partial nuclei acid homology with this same group of viruses. We...

journal_title：Journal of virology

authors： Sahagan BG,Haseltine WA

更新日期：1980-05-01 00:00:00

abstract：:Proviral clones of human immunodeficiency virus type 1 which contained single amino acid changes in the envelope V3 region were constructed. PCR amplification of Sup-T1 T cells transfected with one such mutant, G312T, revealed low levels of virus that resulted in the generation of a revertant virus, in which an alanin...

journal_title：Journal of virology

authors： Morris JF,Sternberg EJ,Gutshall L,Petteway SR Jr,Ivanoff LA

更新日期：1994-12-01 00:00:00

abstract：:BALB/c mice sensitized to herpes simplex virus type 1 (HSV-1) develop a vigorous delayed-type hypersensitivity (DTH) response upon intradermal virus antigen challenge. Although CD4(+) T cells are a key mediator of this response, neutrophils are the most abundant cells at the antigen challenge site both initially and a...

journal_title：Journal of virology

authors： Tumpey TM,Fenton R,Molesworth-Kenyon S,Oakes JE,Lausch RN

更新日期：2002-08-01 00:00:00

abstract：:Aichi virus, a member of the family Picornaviridae, encodes a leader (L) protein of 170 amino acids (aa). The Aichi virus L protein exhibits no significant sequence homology to those of other picornaviruses. In this study, we investigated the function of the Aichi virus L protein in virus growth. In vitro translation ...

journal_title：Journal of virology

authors： Sasaki J,Nagashima S,Taniguchi K

更新日期：2003-10-01 00:00:00

abstract：:Human metapneumovirus (hMPV) is a recently discovered paramyxovirus that is a major cause of lower-respiratory-tract disease. hMPV is associated with more severe disease in infants and persons with underlying medical conditions. Animal studies have shown that the hMPV fusion (F) protein alone is capable of inducing pr...

journal_title：Journal of virology

authors： Williams JV,Chen Z,Cseke G,Wright DW,Keefer CJ,Tollefson SJ,Hessell A,Podsiad A,Shepherd BE,Sanna PP,Burton DR,Crowe JE Jr,Williamson RA

更新日期：2007-08-01 00:00:00

abstract：:Vaccinia extracellular enveloped virus (EEV) is critical for cell-to-cell and long-range virus spread both in vitro and in vivo. The B5R gene encodes an EEV-specific type I membrane protein that is essential for efficient EEV formation. The majority of the B5R ectodomain consists of four domains with homology to short...

journal_title：Journal of virology

authors： Aldaz-Carroll L,Whitbeck JC,Ponce de Leon M,Lou H,Hirao L,Isaacs SN,Moss B,Eisenberg RJ,Cohen GH

更新日期：2005-05-01 00:00:00

abstract：:Infectious pancreatic necrosis virus (IPNV) is a bisegmented, double-stranded RNA (dsRNA) virus of the Birnaviridae family that causes widespread disease in salmonids. Its two genomic segments are encapsulated together with the viral RNA-dependent RNA polymerase, VP1, and the assumed internal protein, VP3, in a single...

journal_title：Journal of virology

authors： Pedersen T,Skjesol A,Jørgensen JB

更新日期：2007-06-01 00:00:00

abstract：:Prion diseases are progressive fatal neurodegenerative illnesses caused by the accumulation of transmissible abnormal prion protein (PrP). To find treatments for prion diseases, we searched for substances from natural resources that inhibit abnormal PrP formation in prion-infected cells. We found that high-molecular-w...

journal_title：Journal of virology

authors： Hamanaka T,Nishizawa K,Sakasegawa Y,Oguma A,Teruya K,Kurahashi H,Hara H,Sakaguchi S,Doh-Ura K

更新日期：2017-02-28 00:00:00

abstract：:The expression of reporter genes driven by the same human elongation factor 1alpha (EF1alpha) promoter in murine leukemia virus (MLV)- and human immunodeficiency virus type 1 (HIV-1)-based vectors was studied in either transfected or virally transduced cells. The HIV-1 vectors consistently expressed 3 to 10 times high...

journal_title：Journal of virology

authors： Zaiss AK,Son S,Chang LJ

更新日期：2002-07-01 00:00:00

abstract：:Previous studies with the herpes simplex virus type 1 X type 2 intertypic recombinant RS6 suggested that the genomic region from 0.11 to 0.14 map units is involved in neurovirulence (R. T. Javier, R. L. Thompson, and J. G. Stevens, J. Virol. 61:1978-1984, 1987). To study this further, we isolated an RS6-derived herpes...

journal_title：Journal of virology

authors： Javier RT,Izumi KM,Stevens JG

更新日期：1988-04-01 00:00:00

abstract：:The deployment of adenovirus serotype 5 (Ad5)-based vectors is hampered by preexisting immunity. When such vectors are delivered intravenously, hepatocyte transduction is mediated by the hexon-coagulation factor X (FX) interaction. Here, we demonstrate that human sera efficiently block FX-mediated cellular binding and...

journal_title：Journal of virology

authors： Parker AL,Waddington SN,Buckley SM,Custers J,Havenga MJ,van Rooijen N,Goudsmit J,McVey JH,Nicklin SA,Baker AH

更新日期：2009-01-01 00:00:00

abstract：:The majority of HIV-1 infections around the world result from non-B clade HIV-1 strains. The CRF01_AE (AE) strain is seen principally in Southeast Asia. AE protease differs by approximately 10% in amino acid sequence from clade B protease and carries several naturally occurring polymorphisms that are associated with d...

journal_title：Journal of virology

authors： Bandaranayake RM,Kolli M,King NM,Nalivaika EA,Heroux A,Kakizawa J,Sugiura W,Schiffer CA

更新日期：2010-10-01 00:00:00

abstract：:Kaposi's sarcoma-associated herpesvirus (KSHV) (also called human herpesvirus 8) is consistently found in Kaposi's sarcoma lesions and in body-cavity-based lymphomas. A 17-kb KSHV lambda clone was obtained directly from a Kaposi's sarcoma lesion. DNA sequence analysis of this clone identified an open reading frame whi...

journal_title：Journal of virology

authors： Li M,Lee H,Yoon DW,Albrecht JC,Fleckenstein B,Neipel F,Jung JU

更新日期：1997-03-01 00:00:00

abstract：:Far-upstream element-binding protein 2 (FBP2) is an internal ribosomal entry site (IRES) trans-acting factor (ITAF) that negatively regulates enterovirus 71 (EV71) translation. This study shows that EV71 infection cleaved FBP2. Live EV71 and the EV71 replicon (but not UV-inactivated virus particles) induced FBP2 cleav...

journal_title：Journal of virology

authors： Chen LL,Kung YA,Weng KF,Lin JY,Horng JT,Shih SR

更新日期：2013-04-01 00:00:00

abstract：:The Us11 protein of herpes simplex virus 1 (HSV-1) is an accessory factor with multiple functions. In virus-infected cells, it inhibits double-stranded RNA-dependent protein kinase (PKR), 2',5'-oligoadenylate synthetase, RIG-I, and MDA-5. However, its precise role is incompletely defined. By screening a human cDNA lib...

journal_title：Journal of virology

authors： Liu X,Main D,Ma Y,He B

更新日期：2018-06-29 00:00:00

abstract：:Apoptosis was postulated as the main barrier to replication of the Autographa californica nuclear polyhedrosis virus (AcMNPV) in a Spodoptera littoralis SL2 cell line (N. Chejanovsky and E. Gershburg, Virology 209:519-525, 1995). Thus, we hypothesized that the viral apoptotic suppressor gene p35 is either poorly expre...

journal_title：Journal of virology

authors： Gershburg E,Rivkin H,Chejanovsky N

更新日期：1997-10-01 00:00:00

abstract：:Comparative surface feature analyses of the VP1 sequences of hepatitis A virus (HAV) and poliovirus type 1 allowed an alignment of the two sequences and an identification of probable HAV neutralization antigenic sites. A synthetic peptide containing the HAV-specific amino acid sequence of one of these sites induced an...

journal_title：Journal of virology

authors： Emini EA,Hughes JV,Perlow DS,Boger J

更新日期：1985-09-01 00:00:00

abstract：UNLABELLED:Many murine leukemia viruses (MLVs) are partially resistant to restriction by mouse APOBEC3 (mA3) and essentially fully resistant to induction of G-to-A mutations by mA3. In contrast, Vif-deficient HIV-1 (ΔVif HIV-1) is profoundly restricted by mA3, and the restriction includes high levels of G-to-A mutation...

journal_title：Journal of virology

authors： Nair S,Sanchez-Martinez S,Ji X,Rein A

更新日期：2014-04-01 00:00:00

abstract：:Previous studies with simian virus 40-transformed mouse 3T3 cells which are temperature sensitive for the expression of the transformed phenotype (ts SV3T3 cells) have shown that T-antigen expression and viral DNA transcription are under cell cycle control. Using these ts SV3T3 cells, we studied the expression of the ...

journal_title：Journal of virology

authors： Zouzias D,Basilico C

更新日期：1979-06-01 00:00:00

abstract：UNLABELLED:Human T-cell lymphotropic virus type 1 (HTLV-1) and HTLV-2 encode auxiliary proteins that play important roles in viral replication, viral latency, and immune escape. The presence of auxiliary protein-encoding open reading frames (ORFs) in HTLV-3, the latest HTLV to be discovered, is unknown. Simian T-cell l...

journal_title：Journal of virology

authors： Turpin J,Journo C,Ko NL,Sinet F,Carpentier A,Galioot A,Edwards D,Vandamme AM,Gazzolo L,Duc Dodon M,Gessain A,Kashanchi F,Balansard I,Lacoste R,Mahieux R

更新日期：2015-01-15 00:00:00

abstract：:RNA silencing is a conserved eukaryotic gene regulatory system in which sequence specificity is determined by small RNAs. Plant RNA silencing also acts as an antiviral mechanism; therefore, viral infection requires expression of a silencing suppressor. The mechanism and the evolution of silencing suppression are still...

journal_title：Journal of virology

authors： Mérai Z,Kerényi Z,Molnár A,Barta E,Válóczi A,Bisztray G,Havelda Z,Burgyán J,Silhavy D

更新日期：2005-06-01 00:00:00

abstract：:Immunological comparisons were made of baculovirus structural proteins by using a modification of the radioimmunological techniques described by Renart et al. (Proc. Natl. Acad. Sci. U.S.A. 76: 3116-3120, 1979) and Towbin et al. (Proc. Natl. Acad. Sci. U.S.A. 76: 4350-4354, 1979). Viral proteins were electrophoresed i...

journal_title：Journal of virology

authors： Smith GE,Summers MD

更新日期：1981-07-01 00:00:00