Comparative analysis of lifestyle factors, screening test use, and clinicopathologic features in association with survival among Asian Americans with colorectal cancer.


BACKGROUND:Colorectal cancer (CRC) diagnoses and disease-specific survival (DSS) vary between ethnic groups in the United States. However, few studies have assessed differences among Asian subgroups. METHODS:The Surveillance, Epidemiology, and End Results (SEER) database was used to identify patients with invasive CRC between 1988 and 2008. Differences in clinicopathologic features, and DSS rates were compared among Asian subgroups. The California Health Interview Survey was used to examine risk factors and screening patterns for CRC. RESULTS:The study included 359 374 patients with 8.4% Asian. Patients in all Asian subgroups were younger (median: 68 years) at diagnosis than non-Hispanic white (NHW) patients (median: 72 years). Most Asian subgroups, except Hawaiians, had better DSS than NHW patients although Asian subgroups had more advanced disease than NHW. Indian/Pakistani patients had a higher 5-year DSS than other Asian subgroups. Obesity proportions were lower in Asian subgroups (<50.2%) than in NHW (59.8%). Vietnamese men and Korean women had the lowest proportions of CRC screening. Advance tumour stages were highly associated with worse DSS in each ethnicity group. High tumour grades were associated with worse DSS in NHW, Filipino, and Chinese. Older age at diagnosis was associated with worse DSS in most ethnicity groups except Hawaiian and Vietnamese. CONCLUSION:Disparities exist between Asians and NHW with CRC, and among various Asian subgroups. Differences in cancer clinicopathologic features, patients' behavioural habits, lifestyle, and screening patterns may explain some differences in CRC survival observed among ethnic groups.


Br J Cancer


Yi M,Xu J,Liu P,Chang GJ,Du XL,Hu CY,Song Y,He J,Ren Y,Wei Y,Yang J,Hunt KK,Li X




Has Abstract


2013-04-16 00:00:00














  • Lymphocyte markers in non-Hodgkin's lymphomas.

    abstract::The lymphocyte marker pattern of non-Hodgkin's lymphoma cells was related to current concepts of lymphoma classification. In a series of 28 lymphomas lymphocyte markers indicated that 2 were of histiocytic origin, 2 were unclassifiable, none were derived from T cells and the remainder were B-cell neoplasms. The immuno...

    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: Payne SV,Smith JL,Jones DB,Wright DH

    更新日期:1977-07-01 00:00:00

  • Mechanisms of relapse in acute leukaemia: involvement of p53 mutated subclones in disease progression in acute lymphoblastic leukaemia.

    abstract::Mutations of the p53 tumour suppressor gene are infrequent at presentation of both acute myeloblastic leukaemia (AML) and acute lymphoblastic leukaemia (ALL), being found in between 5-10% of AML and 2-3% of ALL. Here we have studied the frequency of detection of p53 mutations at relapse of both AML and B-precursor ALL...

    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: Zhu YM,Foroni L,McQuaker IG,Papaioannou M,Haynes A,Russell HH

    更新日期:1999-03-01 00:00:00

  • Correlation between 5-fluorouracil metabolism and treatment response in two variants of C26 murine colon carcinoma.

    abstract::Following an i.p. dose of 150 mg x kg(-1) 5-fluorouracil (5-FU), drug uptake and metabolism over a 2-h period were studied by in vivo (19)F magnetic resonance spectroscopy (MRS) for the murine colon carcinoma lines C26-B (5-FU-insensitive; n=11) and C26-10 (5-FU-sensitive; n=15) implanted s.c. in Balb/C mice. Time cou...

    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: Kamm YJ,Peters GJ,Hull WE,Punt CJ,Heerschap A

    更新日期:2003-08-18 00:00:00

  • Recurrent gains of 1q, 8 and 12 in the Ewing family of tumours by comparative genomic hybridization.

    abstract::Comparative genomic hybridization (CGH) was used to detect copy number changes of DNA sequences in the Ewing family of tumours (ET). We analysed 20 samples from 17 patients. Fifteen tumours (75%) showed copy number changes. Gains of DNA sequences were much more frequent than losses, the majority of the gains affecting...

    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: Armengol G,Tarkkanen M,Virolainen M,Forus A,Valle J,Böhling T,Asko-Seljavaara S,Blomqvist C,Elomaa I,Karaharju E,Kivioja AH,Siimes MA,Tukiainen E,Caballín MR,Myklebost O,Knuutila S

    更新日期:1997-01-01 00:00:00

  • A limited sampling procedure for estimating adriamycin pharmacokinetics in cancer patients.

    abstract::The aim of this study was to find a procedure allowing estimation of individual pharmacokinetic parameters for adriamycin with minimal cost and disturbance for the patient. Twenty-five patients with breast cancer were treated by short infusion of adriamycin at a dose of 12 mg m-2 week-1 (41 courses). Population charac...

    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: Launay MC,Milano G,Iliadis A,Frenay M,Namer N

    更新日期:1989-07-01 00:00:00

  • Prevalence and determinants of human papillomavirus genital infection in men.

    abstract::Four-hundred-forty-five husbands of women with invasive cervical carcinoma, 165 of women with in situ cervical cancer, and 717 of control women (age range 19-82 years) were interviewed and a sample of exfoliated cells from the penis obtained in seven case-control studies conducted by the International Agency for Resea...

    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: Franceschi S,Castellsagué X,Dal Maso L,Smith JS,Plummer M,Ngelangel C,Chichareon S,Eluf-Neto J,Shah KV,Snijders PJ,Meijer CJ,Bosch FX,Muñoz N

    更新日期:2002-03-04 00:00:00

  • A phase 1 dose-escalation study of veliparib with bimonthly FOLFIRI in patients with advanced solid tumours.

    abstract:BACKGROUND:Veliparib is a potent poly(ADP-ribose) polymerase inhibitor. This phase 1 study aimed to establish the maximum tolerated dose (MTD) and recommended phase 2 dose (RP2D) of veliparib combined with various FOLFIRI regimens in patients with solid tumours. METHODS:Patients received veliparib (10-270 mg BID, days...

    journal_title:British journal of cancer

    pub_type: 杂志文章,多中心研究


    authors: Berlin J,Ramanathan RK,Strickler JH,Subramaniam DS,Marshall J,Kang YK,Hetman R,Dudley MW,Zeng J,Nickner C,Xiong H,Komarnitsky P,Shepherd SP,Hurwitz H,Lenz HJ

    更新日期:2018-04-01 00:00:00

  • Nuclear localisation of LASP-1 correlates with poor long-term survival in female breast cancer.

    abstract:BACKGROUND:LIM and SH3 protein 1 (LASP-1) is a nucleo-cytoplasmatic signalling protein involved in cell proliferation and migration and is upregulated in breast cancer in vitro studies have shown that LASP-1 might be regulated by prostate-derived ETS factor (PDEF), p53 and/or LASP1 gene amplification. This current stud...

    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: Frietsch JJ,Grunewald TG,Jasper S,Kammerer U,Herterich S,Kapp M,Honig A,Butt E

    更新日期:2010-05-25 00:00:00

  • Regulation of cell proliferation under extreme and moderate hypoxia: the role of pyrimidine (deoxy)nucleotides.

    abstract::In the present study we have used flow cytometric DNA measurements on synchronised human NHIK 3025 cells to measure cell cycle progression under various conditions of reduced oxygenation. Our data indicate that addition of 0.1 mM deoxycytidine or uridine has no effect on the oxygen-dependent arrest in late G1 or on th...

    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: Amellem O,Löffler M,Pettersen EO

    更新日期:1994-11-01 00:00:00

  • Relationship between physician and patient assessment of performance status and survival in a large cohort of patients with haematologic malignancies.

    abstract:BACKGROUND:Few studies have investigated the relationship between physician and patient-assessed performance status (PS) in blood cancers. METHODS:Retrospective analysis among 1418 patients with haematologic malignancies seen at Dana-Farber Cancer Institute between 2007 and 2014. We analysed physician-patient agreemen...

    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: Liu MA,Hshieh T,Condron N,Wadleigh M,Abel GA,Driver JA

    更新日期:2016-09-27 00:00:00

  • Smoking, alcohol and gastric cancer risk in Korean men: the National Health Insurance Corporation Study.

    abstract::We investigated the risk of gastric cancer by subsite in relation to cigarette smoking and alcohol in a large population-based cohort of 669 570 Korean men in an insurance plan followed for an average 6.5 years, yielding 3452 new cases of gastric cancer, of which 127 were cardia and upper-third gastric cancer, 2409 we...

    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: Sung NY,Choi KS,Park EC,Park K,Lee SY,Lee AK,Choi IJ,Jung KW,Won YJ,Shin HR

    更新日期:2007-09-03 00:00:00

  • Clinical and economic benefit of HPV-load testing in follow-up and management of women postcone biopsy for CIN2-3.

    abstract::This study aimed to evaluate the clinical and economic implications of integrating human papilloma virus (HPV) load testing into the follow-up and management protocol of women postconisation for high-grade cervical intraepithelial neoplasia (CIN2-3). We evaluated 130 suitable women: 63 were screened biannually by Pap ...

    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: Almog B,Gamzu R,Bornstein J,Levin I,Fainaru O,Niv J,Lessing JB,Bar-Am A

    更新日期:2003-07-07 00:00:00

  • The sVEGFR1-i13 splice variant regulates a β1 integrin/VEGFR autocrine loop involved in the progression and the response to anti-angiogenic therapies of squamous cell lung carcinoma.

    abstract:BACKGROUND:While lung adenocarcinoma patients can somewhat benefit from anti-angiogenic therapies, patients with squamous cell lung carcinoma (SQLC) cannot. The reasons for this discrepancy remain largely unknown. Soluble VEGF receptor-1, namely sVEGFR1-i13, is a truncated splice variant of the cell membrane-spanning V...

    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: Abou Faycal C,Brambilla E,Agorreta J,Lepeltier N,Jacquet T,Lemaître N,Emadali A,Lucas A,Lacal PM,Montuenga L,Pio R,Gazzeri S,Eymin B

    更新日期:2018-06-01 00:00:00

  • Comparison of the RNA-amplification based methods RT-PCR and NASBA for the detection of circulating tumour cells.

    abstract::Increasingly, reverse transcriptase polymerase chain reaction (RT-PCR) is used to detect clinically significant tumour cells in blood or bone marrow. This may result in a redefinition of disease-free and clinical relapse. However, its clinical utility may be limited by lack of automation or reproducibility. Recent stu...

    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: Burchill SA,Perebolte L,Johnston C,Top B,Selby P

    更新日期:2002-01-07 00:00:00

  • Animal food intake and cooking methods in relation to endometrial cancer risk in Shanghai.

    abstract::We evaluated animal food intake and cooking methods in relation to endometrial cancer risk in a population-based case-control study in Shanghai, China. A validated food frequency questionnaire was used to collect the usual dietary habits of 1204 cases and 1212 controls aged 30-69 years between 1997 and 2003. Statistic...

    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: Xu WH,Dai Q,Xiang YB,Zhao GM,Zheng W,Gao YT,Ruan ZX,Cheng JR,Shu XO

    更新日期:2006-12-04 00:00:00

  • Two novel human anti-ErbB2 immunoagents are active on trastuzumab-resistant tumours.

    abstract:BACKGROUND:Overexpression of ErbB2 receptor in breast cancer is associated with disease progression and poor prognosis. Trastuzumab, the only humanised anti-ErbB2 antibody currently used in breast cancer, has proven to be effective; however, a relevant problem for clinical practice is that a high fraction of breast can...

    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: Gelardi T,Damiano V,Rosa R,Bianco R,Cozzolino R,Tortora G,Laccetti P,D'Alessio G,De Lorenzo C

    更新日期:2010-02-02 00:00:00

  • Hormone replacement treatment and breast cancer risk: a cooperative Italian study.

    abstract::The relationship between hormone replacement treatment (HRT) and breast cancer risk was analysed using data from a case-control study conducted between June 1991 and February 1994 in six Italian centres on 2569 patients aged below 75 with histologically confirmed breast cancer and 2588 controls admitted to hospital fo...

    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: La Vecchia C,Negri E,Franceschi S,Favero A,Nanni O,Filiberti R,Conti E,Montella M,Veronesi A,Ferraroni M

    更新日期:1995-07-01 00:00:00

  • High basal NF-κB activity in nonpigmented melanoma cells is associated with an enhanced sensitivity to vitamin D3 derivatives.

    abstract:BACKGROUND:Melanoma is highly resistant to current modalities of therapy, with the extent of pigmentation playing an important role in therapeutic resistance. Nuclear factor-κB (NF-κB) is constitutively activated in melanoma and can serve as a molecular target for cancer therapy and steroid/secosteroid action. METHODS...

    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: Janjetovic Z,Brozyna AA,Tuckey RC,Kim TK,Nguyen MN,Jozwicki W,Pfeffer SR,Pfeffer LM,Slominski AT

    更新日期:2011-12-06 00:00:00

  • Individuality in FGF1 expression significantly influences platinum resistance and progression-free survival in ovarian cancer.

    abstract:BACKGROUND:Ovarian cancer is frequently advanced at presentation when treatment is rarely curative. Response to first-line platinum-based chemotherapy significantly influences survival, but clinical response is unpredictable and is frequently limited by the development of drug-resistant disease. METHODS:We used qRT-PC...

    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: Smith G,Ng MT,Shepherd L,Herrington CS,Gourley C,Ferguson MJ,Wolf CR

    更新日期:2012-10-09 00:00:00

  • Hepatocyte growth factor inhibition: a novel therapeutic approach in pancreatic cancer.

    abstract:BACKGROUND:Pancreatic stellate cells (PSCs, which produce the stroma of pancreatic cancer (PC)) interact with cancer cells to facilitate PC growth. A candidate growth factor pathway that may mediate this interaction is the HGF-c-MET pathway. METHODS:Effects of HGF inhibition (using a neutralising antibody AMG102) alon...

    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: Pothula SP,Xu Z,Goldstein D,Biankin AV,Pirola RC,Wilson JS,Apte MV

    更新日期:2016-02-02 00:00:00

  • Alcohol, smoking, passive smoking and caffeine in relation to breast cancer risk in young women. UK National Case-Control Study Group.

    abstract::The UK National Case-Control Study Group has examined the relationship between smoking (both own smoking and passive), alcohol consumption and caffeine consumption and the risk of breast cancer. A total of 755 women with breast cancer diagnosed before the age of 36, each with an age-matched general population control,...

    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: Smith SJ,Deacon JM,Chilvers CE

    更新日期:1994-07-01 00:00:00

  • Involvement of chromosome 6 in endometrial cancer.

    abstract::Cytogenetic investigation was performed on direct preparations of 15 endometrial cancers showing different histotypes. Clonal abnormalities were found in 11 out of 13 analysable cases. The modal chromosome number was near diploid in all cases. The abnormal karyotypes contained relatively simple numerical or structural...

    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: Tibiletti MG,Bernasconi B,Taborelli M,Furlan D,Fabbri A,Franchi M,Taramelli R,Trubia M,Capella C

    更新日期:1997-01-01 00:00:00

  • Breast density and outcome of mammography screening: a cohort study.

    abstract::The purpose of this study was to investigate the effect of breast density on breast cancer (BC) mortality in a mammography screening programme. The cohort included 48 052 women participating in mammography screening in Copenhagen, Denmark, where biennial screening is offered to women aged 50-69 years. We collected inf...

    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: Olsen AH,Bihrmann K,Jensen MB,Vejborg I,Lynge E

    更新日期:2009-04-07 00:00:00

  • The antileukaemic activity of 5-Aza-2 deoxycytidine (Aza-dC) in patients with relapsed and resistant leukaemia.

    abstract::In the present study we demonstrate that Aza-dC in combination with Amsacrine has major antileukaemic properties in patients who have not already received extensive Ara-C therapy. Eight out of 11 patients in their first relapse of acute leukaemia achieved complete remission. Cross resistance between Ara-C and Aza-dC w...

    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: Richel DJ,Colly LP,Kluin-Nelemans JC,Willemze R

    更新日期:1991-07-01 00:00:00

  • Comparison of a new microplate oestrogen receptor (ER) enzyme immunoassay with other ER detection methods.

    abstract::In a study involving 50 breast cancer tumours, we compared two oestrogen receptor (ER) detection methods developed by us--a microplate immunoenzymometric assay (EIA96) and an immunohistochemistry kit (HistoCIS-ER)--with the radioligand assay (RLA), the Abbott immunoenzymometric assay ER-EIA and the reverse transcripta...

    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: Delage V,Deytieux S,Le Doussal V,Degorce F,Bellanger L,Hacene K,Seguin P,Descotes F,Saez S,Spyratos F

    更新日期:1997-01-01 00:00:00

  • Regulation of monocyte MMP-9 production by TNF-alpha and a tumour-derived soluble factor (MMPSF).

    abstract::The matrix metalloprotease MMP-9 localizes to tumour-associated macrophages in human ovarian cancer but little is known of its regulation. Co-culture of human ovarian cancer cells (PEO-1) and a monocytic cell line (THP-1) led to production of 92-kDa proMMP-9. PEO-1-conditioned medium (CM) also stimulated THP-1 cells o...

    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: Leber TM,Balkwill FR

    更新日期:1998-09-01 00:00:00

  • Does type 2 diabetes influence the risk of oesophageal adenocarcinoma?

    abstract::Since hyperinsulinaemia may promote obesity-linked cancers, we compared type 2 diabetes prevalence among oesophageal adenocarcinoma (OAC) patients and population controls. Diabetes increased the risk of OAC (adjusted odds ratio 1.59, 95% confidence interval (CI) 1.04-2.43), although the risk was attenuated after furth...

    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: Neale RE,Doecke JD,Pandeya N,Sadeghi S,Green AC,Webb PM,Whiteman DC,Australian Cancer Study.

    更新日期:2009-03-10 00:00:00

  • Regulation of ITGA3 by the dual-stranded microRNA-199 family as a potential prognostic marker in bladder cancer.

    abstract:BACKGROUND:Based on the microRNA (miRNA) signature of bladder cancer (BC) by deep sequencing, we recently found that several double-stranded mature miRNAs derived from the same pre-miRNAs were sufficiently expressed and acted as tumour suppressors by regulating common target genes in BC. Our deep-sequencing signature o...

    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: Sakaguchi T,Yoshino H,Yonemori M,Miyamoto K,Sugita S,Matsushita R,Itesako T,Tatarano S,Nakagawa M,Enokida H

    更新日期:2017-04-11 00:00:00

  • Analysis of the cytochrome c-dependent apoptosis apparatus in cells from human pancreatic carcinoma.

    abstract::Defects in the apoptotic system are likely to play a role in tumorigenesis. Pancreatic carcinoma cells are extremely resistant to apoptosis induction by chemotherapy suggesting that the apoptosis machinery is faulty. We investigated the integrity of the cytochrome c-dependent apoptotic apparatus in 10 human pancreatic...

    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: Gerhard MC,Schmid RM,Häcker G

    更新日期:2002-03-18 00:00:00

  • Telomerase activity in benign and malignant human thyroid tissues.

    abstract::Telomerase is a specialized ribonucleoprotein polymerase that directs the synthesis of telomerase repeats at chromosome ends. Accumulating evidence has indicated that telomerase is stringently repressed in normal human somatic tissues but reactivated in cancers and immortal cells, suggesting that activation of telomer...

    journal_title:British journal of cancer

    pub_type: 杂志文章


    authors: Cheng AJ,Lin JD,Chang T,Wang TC

    更新日期:1998-06-01 00:00:00