Interaction of RhoD and ZIP kinase modulates actin filament assembly and focal adhesion dynamics.

abstract：:Cholinesterases in the oat cell were found to be distributed in the cell wall (50%) and cytoplasm (42%). Activity of the cytosolic enzyme was inhibited about 80% by 1 mM Ca2+. The enzyme activity was also inhibited by Mn2+, but no inhibition by Mg2+ was observed. Effects of red light and calcium ion on the enzyme acti...

journal_title：Biochemical and biophysical research communications

authors： Kim HY,Kim TI,Kim HK,Chae Q

更新日期：1990-05-31 00:00:00

abstract：:ATP-binding cassette transporter D2 (D2) is an ABC half transporter that is thought to promote the transport of very long-chain fatty acyl-CoAs into peroxisomes. Both D2 and peroxisomes increase during adipogenesis. Although peroxisomes are essential to both catabolic and anabolic lipid metabolism, their function, and...

journal_title：Biochemical and biophysical research communications

authors： Liu X,Liu J,Lester JD,Pijut SS,Graf GA

更新日期：2015-01-02 00:00:00

abstract：:Matrin 3 is a nuclear matrix protein that has been implicated in interacting with other nuclear proteins to anchor hyperedited RNAs to the nuclear matrix, in modulating the activity of proximal promoters, and as the main PKA substrate following NMDA receptor activation. In our proteome-wide selections for calmodulin (...

journal_title：Biochemical and biophysical research communications

authors： Valencia CA,Ju W,Liu R

更新日期：2007-09-21 00:00:00

abstract：:Palmar fibromatosis is a benign fibroproliferative tumor of unknown etiology, with a high rate of recurrence after excision. The offending cells of palmar fibromatosis are myofibroblasts and the cellular origin of other myofibroblasts has previously been reported to be the bone marrow. However, further clarification o...

journal_title：Biochemical and biophysical research communications

authors： Wang JP,Hui YJ,Wang ST,Huang YC,Chiang ER,Liu CL,Chen TH,Hung SC

更新日期：2011-05-06 00:00:00

abstract：:The monoclonal antibody 6E2 raised against the embryonal carcinoma cell line NCR-G3 had been shown to also react with human germ cells. Thin-layer chromatography (TLC) immunostaining revealed that 6E2 specifically reacts with sialosylglobopenta osylceramide (sialylGb5), which carries an epitope of stage-specific embry...

journal_title：Biochemical and biophysical research communications

authors： Sato B,Katagiri YU,Miyado K,Akutsu H,Miyagawa Y,Horiuchi Y,Nakajima H,Okita H,Umezawa A,Hata J,Fujimoto J,Toshimori K,Kiyokawa N

更新日期：2007-12-28 00:00:00

abstract：:Novel conformation-specific antibodies were raised against a cyclic chimeric dodecapeptidyl multiple antigen peptide (cCD-MAP) constructed with a spacer-armed Gly-Asp dipeptide and two pentapeptides (S(169)-Q(170)-K(171)-E(172)-G(173) of CCR5 and E(179)-A(180)-D(181)-D(182)-R(183) of CXCR4) which are components of the...

journal_title：Biochemical and biophysical research communications

authors： Misumi S,Takamune N,Ido Y,Hayashi S,Endo M,Mukai R,Tachibana K,Umeda M,Shoji S

更新日期：2001-08-03 00:00:00

abstract：:The mRNA encoding the Type II isozyme of hexokinase was markedly elevated in livers of transgenic mice overexpressing the transcriptionally active nuclear form of sterol regulatory element binding protein-1a (nSREBP-1a), but not in transgenic mice overexpressing the nSREBP-1c or nSREBP-2 isoforms. Cellulose acetate el...

journal_title：Biochemical and biophysical research communications

authors： Sebastian S,Horton JD,Wilson JE

更新日期：2000-04-21 00:00:00

abstract：:This study describes the purification and characterization of an aminopeptidase from human cerebrospinal fluid capable of degrading delta-sleep-inducing-peptide (DSIP). The enzyme has an apparent molecular weight of approximately 80,000 dalton. It is sensitive towards amastatin, bestatin and EDTA and is optimally acti...

journal_title：Biochemical and biophysical research communications

authors： Nyberg F,Thörnwall M,Hetta J

更新日期：1990-03-30 00:00:00

abstract：:Bloom Syndrome (BS) is a human autosomal genetic disorder characterized by a predisposition to a variety of malignant tumors. The gene responsible for BS encodes a protein (BLM) consisting of 1417 amino acids with a nuclear localization signal in the C-terminal region, which is a member of the RecQ helicase family. We...

journal_title：Biochemical and biophysical research communications

authors： Suzuki H,Seki M,Kobayashi T,Kawabe Yi,Kaneko H,Kondo N,Harata M,Mizuno S,Masuko T,Enomoto T

更新日期：2001-08-17 00:00:00

abstract：:The aim of this study was to follow the changes of estrogen treatment on osteoblastic MBA-15 cells derived from marrow stromal origin. Following exposure to estrogen, the cells' patterns of protein synthesis and expression were monitored. The proteins synthesized by MBA-15 cells were identified in cell lysate fraction...

journal_title：Biochemical and biophysical research communications

authors： Benayahu D

更新日期：1997-04-07 00:00:00

abstract：:Ubiquitous calpains (calpain I and II) are generally recognized as cytosolic proteins. Recently, mitochondrial localized calpain I (μ-calpain) has been identified. Activation of mito-μ-calpain cleaves apoptosis inducing factor (AIF), a flavoprotein located within the mitochondrial intermembrane space, in liver mitocho...

journal_title：Biochemical and biophysical research communications

authors： Chen Q,Paillard M,Gomez L,Ross T,Hu Y,Xu A,Lesnefsky EJ

更新日期：2011-12-02 00:00:00

abstract：:Mycobacterium tuberculosis (TB) small heat shock protein Hsp16.3 was found to be a major membrane protein that is most predominantly expressed under oxidative stress and is localized to the thickened cell envelope. Gene knock-out studies indicate that the Hsp16.3 protein is required for TB to grow in its host macropha...

journal_title：Biochemical and biophysical research communications

authors： Abulimiti A,Qiu X,Chen J,Liu Y,Chang Z

更新日期：2003-05-23 00:00:00

abstract：:To obtain antiparallel and parallel dimers of alpha-human atrial natriuretic peptide (alpha-hANP), two fully protected peptides I and II having the same amino acid sequence as alpha-hANP with different protective groups at the cysteinyl residues were synthesized, the former having Acm and Npys and the latter MeBzl and...

journal_title：Biochemical and biophysical research communications

authors： Chino N,Yoshizawa-Kumagaye K,Noda Y,Watanabe TX,Kimura T,Sakakibara S

更新日期：1986-12-15 00:00:00

abstract：BACKGROUND:Resistin is associated with insulin resistance, and determining its developmental and molecular mechanisms may help the development of novel treatments. MicroRNAs (miRNAs) are involved in many physiological and pathological processes as negative regulators. However, it remains unclear whether miRNAs play a r...

journal_title：Biochemical and biophysical research communications

authors： Wen F,Yang Y,Jin D,Sun J,Yu X,Yang Z

更新日期：2014-03-07 00:00:00

abstract：:Mutations in collagen II are associated with spondyloepiphyseal dysplasia, a group of heritable diseases whose common features include aberrations of skeletal growth. The mechanisms through which mutations in collagen II affect the cartilaginous tissues are complex and include both intracellular and extracellular proc...

journal_title：Biochemical and biophysical research communications

authors： Gawron K,Jensen DA,Steplewski A,Fertala A

更新日期：2010-05-28 00:00:00

abstract：:Mycobacterium tuberculosis, the causative agent of tuberculosis disease, is one among the deadliest pathogens in the world. Due to long treatment regimen, HIV co-infection, persistence of bacilli in latent form and development of XDR and TDR strains of Mtb, tuberculosis has posed serious concerns for managing the dise...

journal_title：Biochemical and biophysical research communications

authors： Gopalan A,Bhagavat R,Chandra N,Subbarao SH,Raja A,Bethunaickan R

更新日期：2018-02-12 00:00:00

abstract：:Metallothionein (MT) is effective in the prevention of diabetic cardiomyopathy, and hypoxia-inducible factor-1 (HIF-1) is known to control vascular endothelial growth factor (VEGF) gene expression and regulate angiogenesis in diabetic hearts. We examined whether or not MT affects HIF-1 activity in the heart of diabeti...

journal_title：Biochemical and biophysical research communications

authors： Feng W,Wang Y,Cai L,Kang YJ

更新日期：2007-08-17 00:00:00

abstract：:Major blood stage antimalarial drugs like chloroquine and artemisinin target the heme detoxification process of the malaria parasite. Hemozoin formation reactions in vitro using the Plasmodium falciparum histidine-rich protein-2 (Pfhrp-2), lipids, and auto-catalysis are slow and could not explain the speed of detoxifi...

journal_title：Biochemical and biophysical research communications

authors： Pandey AV,Babbarwal VK,Okoyeh JN,Joshi RM,Puri SK,Singh RL,Chauhan VS

更新日期：2003-09-05 00:00:00

abstract：:Stefin B is the major general cytosolic protein inhibitor of cysteine cathepsins. Its main function is to protect the organism against the activity of endogenous potentially hazardous proteases accidentally released from lysosomes. In this study, we investigated the possible effect of endosomal/lysosomal aspartic cath...

journal_title：Biochemical and biophysical research communications

authors： Železnik TZ,Kadin A,Turk V,Dolenc I

更新日期：2015-09-18 00:00:00

abstract：:Osteoporosis is a common bone disorder with adverse effects on oral osseointegration, and the effects of metformin on bone metabolism have received increasing attention. The aim of the present study was to test the hypothesis that metformin promoted osteogenesis of bone mesenchymal stem cells (BMSCs) and osseointegrat...

journal_title：Biochemical and biophysical research communications

authors： Lin J,Xu R,Shen X,Jiang H,Du S

更新日期：2020-10-15 00:00:00

abstract：:In cranial skeletal development, the establishment of the ectomesenchymal lineage within the cranial neural crest is of great significance. Fgfs are polypeptide growth factors with diverse functions in development and metabolism. Fgf20b knockdown zebrafish embryos showed dysplastic neurocranial and pharyngeal cartilag...

journal_title：Biochemical and biophysical research communications

authors： Yamauchi H,Goto M,Katayama M,Miyake A,Itoh N

更新日期：2011-06-17 00:00:00

abstract：:The narrow leaf1 (nal1) mutant of rice (Oryza sativa L.) exhibits a narrow leaf phenotype. Previous studies have shown that NAL1 modulates leaf size by affecting vein patterning and cell division; however, the underlying mechanism remains unclear. Here, we report that the nal1 mutant shows reduced size of the leaf aba...

journal_title：Biochemical and biophysical research communications

authors： Lin L,Zhao Y,Liu F,Chen Q,Qi J

更新日期：2019-08-27 00:00:00

abstract：:Sequences coding for the cytoplasmic and transmembrane domains were removed from the cDNA of the human Golgi resident membrane protein beta 1,4 galactosyltransferase (gal-T). The remaining sequences coding for the stem and catalytical domains of this glycosyltransferase were fused to sequences coding for the yeast inv...

journal_title：Biochemical and biophysical research communications

authors： Kleene R,Krezdorn CH,Watzele G,Meyhack B,Herrmann GF,Wandrey C,Berger EG

更新日期：1994-05-30 00:00:00

abstract：:A single bout of exercise is known to increase the insulin sensitivity of skeletal muscle; however, the underlying mechanism of this phenomenon is not fully understood. Because a single bout of exercise induces a transient increase in blood interleukin-6 (IL-6) level, we hypothesized that the enhancement of insulin se...

journal_title：Biochemical and biophysical research communications

authors： Ikeda SI,Tamura Y,Kakehi S,Sanada H,Kawamori R,Watada H

更新日期：2016-05-13 00:00:00

abstract：:Farnesylation of p21Ras is required for translocation to the plasma membrane and subsequent activation by growth factors. Previously we demonstrated that insulin stimulates the phosphorylation of farnesyltransferase (FTase) and its activity, whereby the amount of farnesylated p21Ras anchored at the plasma membrane is ...

journal_title：Biochemical and biophysical research communications

authors： Solomon CS,Goalstone ML

更新日期：2001-07-13 00:00:00

abstract：:The role of microRNAs (miRNAs) in how microbiota influence the host intestinal immune system is not fully understood. We compared the expression profiles of miRNAs and mRNAs in lamina propria leukocytes (LPL) in the large intestines of germ-free (GF) and specific pathogen-free (SPF) mice. Microarray analysis revealed ...

journal_title：Biochemical and biophysical research communications

authors： Ohsaka F,Karatsu Y,Kadota Y,Tochio T,Takemura N,Sonoyama K

更新日期：2021-01-01 00:00:00

abstract：:We investigated the regulation of Hsp27 phosphorylation by protein kinase C δ (PKCδ) during etoposide-induced apoptosis. The phosphorylation of Hsp27 at Ser78 was temporally correlated with the proteolytic activation of PKCδ during apoptosis. Hsp27 phosphorylation was dependent on the activity of PKCδ since treatment ...

journal_title：Biochemical and biophysical research communications

authors： Choi JS,Oh JI,Na M,Lee SK,Joo SH

更新日期：2012-10-05 00:00:00

abstract：:Zinc ion in solution yields a 560-fold enhancement in the kinetic inhibition of carboxypeptidase A by the simple heterocycle imidazole, behavior attributed to formation of a ternary complex of the three species. However, the effect is partially negated by formation of less-inhibitory Zn2+(C3H4N2)2-4 coordination compl...

journal_title：Biochemical and biophysical research communications

authors： Mock WL,Wang L

更新日期：1999-04-02 00:00:00

abstract：:In rat adrenal dispersed cells, both vanadyl and vanadate inhibited ACTH-stimulated steroidogenesis and the formation of cAMP, whereas these compounds did not inhibit the cAMP-dependent steroidogenesis. Then, the membrane fraction was prepared and activated by various secretagogues including ACTH, Gpp(NH)p, GTP gamma ...

journal_title：Biochemical and biophysical research communications

authors： Hayashi Y,Kimura T

更新日期：1985-08-15 00:00:00

abstract：:It has been generally viewed that salicylates ameliorate type 2 diabetes through interfering with the NF-kappaB signaling. Earlier studies indicated that IKKbeta was the key for the development of insulin resistance. However, it was unknown whether IKKbeta itself, or its downstream target, NF-kappaB, plays major roles...

journal_title：Biochemical and biophysical research communications

authors： Chen F

更新日期：2005-06-24 00:00:00