Hypothalamic-pituitary-adrenocortical responses to psychological stress and caffeine in men at high and low risk for hypertension.

Abstract:

OBJECTIVE:This study examined pituitary-adrenocortical responses to dietary doses of caffeine (3.3 mg/kg, equivalent to 2 to 3 cups of coffee), alone and combined with behavioral stress, in men at high risk versus low risk for hypertension. A randomized, double-blind, caffeine-placebo crossover design was used. METHOD:Adrenocorticotropic hormone (ACTH) and cortisol levels in plasma were assessed at rest and in response to 60-minutes of continuous work on a mental stressor (arithmetic) and a psychomotor task (reaction time) on four test sessions held on separate days. RESULTS:Tasks alone caused greater ACTH and cortisol increases in high risk men than in the low risk group. Caffeine alone elevated ACTH and cortisol in both groups, with more immediate responses in the high risk group. Both groups showed significant ACTH and cortisol responses to caffeine plus tasks, with the high risk group showing more persistent elevations. The high risk group also showed the highest levels of ACTH and cortisol after caffeine plus tasks. CONCLUSIONS:These findings demonstrate for the first time the combined effects of caffeine plus stress on ACTH and demonstrate greater corticosteroid effects in hypertension-prone men. As such, they may have implications for the dietary use of caffeine during periods of stress and in those at risk for hypertension.

journal_name

Psychosom Med

journal_title

Psychosomatic medicine

authors

al'Absi M,Lovallo WR,McKey B,Sung BH,Whitsett TL,Wilson MF

doi

10.1097/00006842-199807000-00021

subject

Has Abstract

pub_date

1998-07-01 00:00:00

pages

521-7

issue

4

eissn

0033-3174

issn

1534-7796

journal_volume

60

pub_type

临床试验,杂志文章,随机对照试验
  • Ventricular tachyarrhythmias and mortality in patients with an implantable cardioverter defibrillator: impact of depression in the MIDAS cohort.

    abstract:OBJECTIVE:We examined whether depression is independently associated with implantable cardioverter defibrillator (ICD) therapy for ventricular tachyarrhythmias and mortality. METHODS:A cohort of 430 consecutive patients with a first-time ICD (79% men; mean [standard deviation] age = 57.8 [12.1] years) completed the Ho...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0000000000000017

    authors: Mastenbroek MH,Versteeg H,Jordaens L,Theuns DA,Pedersen SS

    更新日期:2014-01-01 00:00:00

  • Decreased bone mineral density in medicated psychiatric patients.

    abstract::Osteoporosis is a common problem in postmenopausal women. It has been linked to estrogen deficiency, other neuroendocrine processes such as hypercortisolemia and male hypogonadism, nutritional deficiencies, and other mechanisms. Some of these changes have been also reported in male and female patients with mental diso...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199509000-00011

    authors: Halbreich U,Rojansky N,Palter S,Hreshchyshyn M,Kreeger J,Bakhai Y,Rosan R

    更新日期:1995-09-01 00:00:00

  • Asian-American deaths near the Harvest Moon Festival.

    abstract:OBJECTIVE:Reexamine the claim that elderly Chinese-American women are able to prolong their lives until after the celebration of the Harvest Moon Festival. METHODS:See if independent 1985 to 2000 data for Chinese-, Korean-, and Vietnamese-Americans replicate results that were reported using 1960 to 1984 data for Chine...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/01.psy.0000127875.38685.ba

    authors: Smith G

    更新日期:2004-05-01 00:00:00

  • Inhibition of subjective and physiological sexual arousal in women by clonidine.

    abstract:OBJECTIVE:The present investigation was designed to provide the first empirical examination of the effects of clonidine, a selective alpha 2-adrenergic agonist, on sexual arousal in women with and without prior sympathetic nervous system [SNS] stimulation by exercise. The purpose was to help elucidate the influence of ...

    journal_title:Psychosomatic medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00006842-199707000-00010

    authors: Meston CM,Gorzalka BB,Wright JM

    更新日期:1997-07-01 00:00:00

  • Self-Help for Medically Unexplained Symptoms: A Systematic Review and Meta-Analysis.

    abstract:OBJECTIVE:Medically unexplained symptoms (MUS), which are highly prevalent in all fields of medicine, are considered difficult to treat. The primary objective of this systematic review and meta-analysis was to assess the efficacy of self-help for adults with MUS. METHODS:Four electronic databases were searched for rel...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/PSY.0000000000000325

    authors: van Gils A,Schoevers RA,Bonvanie IJ,Gelauff JM,Roest AM,Rosmalen JG

    更新日期:2016-07-01 00:00:00

  • Psychotic, Mood, and Anxiety Disorders and Venous Thromboembolism: A Systematic Review and Meta-Analysis.

    abstract:OBJECTIVE:Several studies have shown that psychiatric disorders can be associated with venous thromboembolism (VTE) risk, that is, pulmonary embolism (PE) and/or deep vein thrombosis (DVT). In this study, we provide a systematic review and meta-analyses of the studies addressing this issue. METHODS:All studies address...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0000000000000863

    authors: Kowal C,Peyre H,Amad A,Pelissolo A,Leboyer M,Schürhoff F,Pignon B

    更新日期:2020-11-01 00:00:00

  • The relationship between cardiovascular reactivity in the laboratory and heart rate response in real life: active coping and beta blockade.

    abstract::Earlier studies suggest that cardiovascular responses in the laboratory and in the field are likely to be related when the laboratory tasks involve active coping, when the field measure is taken continuously, and when there is allowance for the effects of autocorrelation and physical activity on the ambulant cardiovas...

    journal_title:Psychosomatic medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00006842-199407000-00013

    authors: Johnston DW,Schmidt TF,Albus C,Vagt S,McSorley K,Klingmann I,Bethge H

    更新日期:1994-07-01 00:00:00

  • Depressive symptoms and mortality in patients after kidney transplantation: a prospective prevalent cohort study.

    abstract:OBJECTIVE:To analyze in a prospective cohort study if depressive symptoms are an independent predictor of mortality in kidney transplant recipients. METHODS:Data from 840 transplanted patients followed at a single outpatient transplant center were analyzed. Sociodemographic parameters and clinical data were collected ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e3181dbbb7d

    authors: Novak M,Molnar MZ,Szeifert L,Kovacs AZ,Vamos EP,Zoller R,Keszei A,Mucsi I

    更新日期:2010-07-01 00:00:00

  • Behavioral and physiological effects of a beta blocker and relaxation therapy on mild hypertensives.

    abstract::In this industrial-based study we compared the blood pressure (BP)-lowering effectiveness of relaxation, a beta blocker, and the combined use of these two treatments in 47 untreated, mildly hypertensive blue collar steel workers. Using a randomized two by two factorial design, patients received either nadolol or place...

    journal_title:Psychosomatic medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00006842-198909000-00004

    authors: Adsett CA,Bellissimo A,Mitchell A,Wilczynski N,Haynes RB

    更新日期:1989-09-01 00:00:00

  • Mental disorders and hypertension: factors associated with awareness and treatment of hypertension in the general population of Germany.

    abstract:OBJECTIVE:The aim of the present study was to identify the association between mental disorders and awareness and treatment of hypertension in a large representative community sample. METHODS:The analysis was based on data from 4149 respondents, ages 18 to 65 years, from the German National Health Interview and Examin...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/01.psy.0000204883.77284.6b

    authors: Schmitz N,Thefeld W,Kruse J

    更新日期:2006-03-01 00:00:00

  • Personality predictors of longevity: activity, emotional stability, and conscientiousness.

    abstract:OBJECTIVE:To examine the association between personality traits and longevity. METHODS:Using the Guilford-Zimmerman Temperament Survey, personality traits were assessed in 2359 participants (38% women; age = 17 to 98 years, mean = 50 years) from the Baltimore Longitudinal Study of Aging, starting in 1958. Over the dur...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e31817b9371

    authors: Terracciano A,Löckenhoff CE,Zonderman AB,Ferrucci L,Costa PT Jr

    更新日期:2008-07-01 00:00:00

  • Psychosocial work characteristics and social support as predictors of SF-36 health functioning: the Whitehall II study.

    abstract:OBJECTIVE:To assess whether work characteristics and social support are predictors of physical, psychological, and social functioning. METHOD:Work characteristics (Karasek and Siegrist models) and social support at baseline were used to predict health functioning measured by the SF-36 General Health Survey 5 years lat...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199805000-00004

    authors: Stansfeld SA,Bosma H,Hemingway H,Marmot MG

    更新日期:1998-05-01 00:00:00

  • Relationships Matter: Progress and Challenges in Research on the Health Effects of Intimate Relationships.

    abstract::Social connections play an important role in health and disease and provide opportunities for clinical and public health interventions. Marriage and similar intimate relationships play a central role in the potential health benefits of positive social connections. This editorial provides an integrative perspective on ...

    journal_title:Psychosomatic medicine

    pub_type: 评论,社论

    doi:10.1097/PSY.0000000000000660

    authors: Smith TW

    更新日期:2019-01-01 00:00:00

  • Prediction of daily food intake as a function of measurement modality and restriction status.

    abstract:OBJECTIVE:Research on eating relies on various indices (e.g., stable, momentary, neural) to accurately reflect food-related reactivity (e.g., disinhibition) and regulation (e.g., restraint) outside the laboratory. The degree to which they differentially predict real-world consumption remains unclear. Further, the predi...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0000000000000187

    authors: Giuliani NR,Tomiyama AJ,Mann T,Berkman ET

    更新日期:2015-06-01 00:00:00

  • Low Control and High Demands at Work as Risk Factors for Suicide: An Australian National Population-Level Case-Control Study.

    abstract:OBJECTIVE:Previous research suggests that psychosocial job stressors may be plausible risk factors for suicide. This study assessed the relationship between psychosocial job stressors and suicide mortality across the Australian population. METHODS:We developed a job exposure matrix to objectively measure job stressors...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0000000000000389

    authors: Milner A,Spittal MJ,Pirkis J,Chastang JF,Niedhammer I,LaMontagne AD

    更新日期:2017-04-01 00:00:00

  • Defective nitric oxide-cyclic guanosine monophosphate signaling in patients with bipolar disorder: a potential role for platelet dysfunction.

    abstract:OBJECTIVE:Bipolar disorder (BD) is associated with elevated cardiovascular mortality rates. We investigated the modulation of l-arginine-nitric oxide (NO) signaling in platelets from patients with BD at different phases. METHODS:Platelets obtained from 28 patients with BD and 10 healthy volunteers were analyzed for l-...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e3182689460

    authors: Fontoura PC,Pinto VL,Matsuura C,Resende Ade C,de Bem GF,Ferraz MR,Cheniaux E,Brunini TM,Mendes-Ribeiro AC

    更新日期:2012-10-01 00:00:00

  • Regional prevalence of fatiguing illnesses in the United States before and after the terrorist attacks of September 11, 2001.

    abstract:OBJECTIVE:Stress or emotional traumas are considered risk factors for unexplained fatiguing illnesses. From July to December 2001, the Centers for Disease Control and Prevention conducted a multigeographical pilot study to test the feasibility of a survey to estimate the prevalence of fatiguing illnesses in the United ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/01.psy.0000138116.12495.a2

    authors: Heim C,Bierl C,Nisenbaum R,Wagner D,Reeves WC

    更新日期:2004-09-01 00:00:00

  • Mood and somatic symptoms during pregnancy.

    abstract::A predominantly white, middle class sample of pregnant women (N = 93) completed the AACL (Anxiety), the DACL (Depressive Mood), the SCL (Somatic Symptoms) and the IPAT Anxiety Questionnaire at the second, fifth and eighth months of pregnancy. A menstrual history questionnaire was administered on the first testing occa...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-197503000-00004

    authors: Lubin B,Gardener SH,Roth A

    更新日期:1975-03-01 00:00:00

  • Moderating effects of moderate-intensity physical activity in the relationship between depressive symptoms and interleukin-6 in primary care patients.

    abstract:OBJECTIVE:To determine whether the relationship between interleukin (IL)-6 and depressive symptoms is moderated by participation in moderate-intensity physical activity in a sample of primary care patients. Elevated inflammation has been associated with a number of poor health outcomes. Depressive symptoms may be relat...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e3182108412

    authors: Rethorst CD,Moynihan J,Lyness JM,Heffner KL,Chapman BP

    更新日期:2011-04-01 00:00:00

  • The effects of expressive writing on lung function, quality of life, medication use, and symptoms in adults with asthma: a randomized controlled trial.

    abstract:OBJECTIVES:Asthma is a chronic condition affecting 300 million people worldwide. Management involves adherence to pharmacological treatments such as corticosteroids and β-agonists, but residual symptoms persist. As asthma symptoms are exacerbated by stress, one possible adjunct to pharmacological treatment is expressiv...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/PSY.0000000000000166

    authors: Smith HE,Jones CJ,Hankins M,Field A,Theadom A,Bowskill R,Horne R,Frew AJ

    更新日期:2015-05-01 00:00:00

  • Is cancer risk associated with anger control and negative affect? Findings from a prospective cohort study.

    abstract:OBJECTIVE:To examine the associations between anger control and negative affect and the risk of five common cancers and total cancers. Possible associations between emotional states and the risk of cancer have long been postulated. METHODS:Prospective cohort study with average follow-up of 9 years. A total of 19,730 a...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e31814d4e6a

    authors: White VM,English DR,Coates H,Lagerlund M,Borland R,Giles GG

    更新日期:2007-09-01 00:00:00

  • Hypertension affects neurobehavioral functioning.

    abstract::This study compared the neurobehavioral performance of hypertensive and normotensive men and women using neuropsychological, information-processing, and psychometric assessments. One hundred subjects, including 68 hypertensive and 32 normotensive individuals, completed a test battery that yielded scores on measures of...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-199301000-00008

    authors: Blumenthal JA,Madden DJ,Pierce TW,Siegel WC,Appelbaum M

    更新日期:1993-01-01 00:00:00

  • Stress exposure, psychological distress, and physiological stress activation in midlife women with insomnia.

    abstract:OBJECTIVE:The objective of this study was to describe perceived and polysomnograhic (PSG) sleep patterns and determine whether stress exposure, psychological distress, and physiological stress activation differed among midlife women with psychophysiologic-type (PP-type) or subjective only-type (SO-type) insomnia or no ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/01.psy.0000024235.11538.9a

    authors: Shaver JL,Johnston SK,Lentz MJ,Landis CA

    更新日期:2002-09-01 00:00:00

  • Screening for DSM-5 Somatic Symptom Disorder: Diagnostic Accuracy of Self-Report Measures Within a Population Sample.

    abstract:OBJECTIVE:The new DSM-5 somatic symptom disorder was introduced to improve the diagnosis of persons experiencing what used to be called somatoform disorders. So far, it is unclear whether existing self-report measures are useful to detect the new somatic symptom disorder. This study investigates the diagnostic accuracy...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0000000000000530

    authors: Laferton JAC,Stenzel NM,Rief W,Klaus K,Brähler E,Mewes R

    更新日期:2017-11-01 00:00:00

  • Self-attention, life stress, and illness: a prospective study.

    abstract::Using a prospective design, this study examined the hypothesis that a predisposition to focus on internal aspects of the self serves as a stress resistance resource. One hundred and twenty subjects filled out the Private Self-Consciousness inventory, a schedule of recent life events and a symptom checklist. Two months...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/00006842-198509000-00007

    authors: Suls J,Fletcher B

    更新日期:1985-09-01 00:00:00

  • Characteristics of Autonomic Activity and Reactivity During Rest and Emotional Processing and Their Clinical Correlations in Somatic Symptom Disorder.

    abstract:OBJECTIVE:Altered autonomic nervous system activity is considered to be involved in the pathophysiology of somatic symptom disorder (SSD). This study aimed to investigate whether patients with SSD have disturbed autonomic activity during rest and reactivity to emotional processing and whether altered autonomic nervous ...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0000000000000622

    authors: Lee D,Kim SJ,Cheon J,Hwang EH,Jung YC,Kang JI

    更新日期:2018-10-01 00:00:00

  • Smoking status and nicotine administration differentially modify hemodynamic stress reactivity in men and women.

    abstract:OBJECTIVES:To investigate the impact of cigarette smoking and oral contraceptive (OC) use on hemodynamic stress responses of women. Also, to examine gender differences in stress reactivity as a function of smoking status and acute nicotine administration. METHODS:Thirty men and 46 women, differing in smoking status an...

    journal_title:Psychosomatic medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00006842-199705000-00012

    authors: Girdler SS,Jamner LD,Jarvik M,Soles JR,Shapiro D

    更新日期:1997-05-01 00:00:00

  • Evidence of early retinal microvascular changes in patients with type 2 diabetes and depression.

    abstract:OBJECTIVE:To examine retinal vascular caliber, an indicator of early microvascular disease and depression in patients with Type 2 diabetes. METHODS:We conducted a clinic-based study, comparing participants with Type 2 diabetes with major depression (n = 43), without depression (n = 49), and healthy controls without di...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0b013e3181da90f4

    authors: Nguyen TT,Wong TY,Islam FM,Hubbard L,Ajilore O,Haroon E,Darwin C,Esser B,Kumar A

    更新日期:2010-07-01 00:00:00

  • Effects of psychological treatment on cancer patients: a critical review.

    abstract::Twenty-two studies on the effects of psychological treatment on cancer patients are reviewed. Only studies that compared one or more experimental conditions with at least one control group have been considered. The studies were evaluated with respect to a) research methods, b) psychological interventions, and c) resul...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章,评审

    doi:10.1097/00006842-199207000-00011

    authors: Trijsburg RW,van Knippenberg FC,Rijpma SE

    更新日期:1992-07-01 00:00:00

  • The Effect of Light-Intensity Cycling on Mood and Working Memory in Response to a Randomized, Placebo-Controlled Design.

    abstract:OBJECTIVE:Prior attempts to measure psychological responses to exercise are potentially limited by a failure to account for participants' expectations, the absence of a valid exercise placebo, and demand characteristics. The purpose of this study was to explore the main and interactive effects of a manipulation designe...

    journal_title:Psychosomatic medicine

    pub_type: 杂志文章

    doi:10.1097/PSY.0000000000000381

    authors: Lindheimer JB,OʼConnor PJ,McCully KK,Dishman RK

    更新日期:2017-02-01 00:00:00