Abstract:
:The pituitary is the master endocrine gland of the body. It undergoes many changes after birth, and these changes may be mediated by the differentiation of pituitary stem cells. Stem cells in any tissue source must display (1) pluripotent capacity, (2) capacity for indefinite self-renewal, and (3) a lack of specialization. Unlike neural stem cells identified in the hippocampus and subventricular zone, pituitary stem cells are not associated with one specific cell type. There are many major candidates that are thought to be potential pituitary stem cell sources. This article reviews the evidence for each of the major cell types and discuss the implications of identifying a definitive pituitary stem cell type.
journal_name
Pituitaryjournal_title
Pituitaryauthors
Nassiri F,Cusimano M,Zuccato JA,Mohammed S,Rotondo F,Horvath E,Syro LV,Kovacs K,Lloyd RVdoi
10.1007/s11102-013-0470-8subject
Has Abstractpub_date
2013-09-01 00:00:00pages
413-8issue
3eissn
1386-341Xissn
1573-7403journal_volume
16pub_type
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