Drugs and prolactin.

Abstract:

:Medications commonly cause hyperprolactinemia and their use must be differentiated from pathologic causes. The most common medications to cause hyperprolactinemia are the antipsychotic agents, although some of the newer atypical antipsychotics do not do so. Other medications causing hyperprolactinemia include antidepressants, antihypertensive agents, and drugs which increase bowel motility. Often, the medication-induced hyperprolactinemia is symptomatic, causing galactorrhea, menstrual disturbance, and erectile dysfunction. In the individual patient, it is important differentiate hyperprolactinemia due to a medication from a structural lesion in the hypothalamic-pituitary area. This can be done by stopping the medication temporarily to determine if the prolactin (PRL) levels return to normal, switching to another medication in the same class which does not cause hyperprolactinemia (in consultation with the patient's physician and/or psychiatrist), or by performing an MRI or CT scan. If the hyperprolactinemia is symptomatic, management strategies include switching to an alternative medication which does not cause hyperprolactinemia, using estrogen/testosterone replacement, or cautiously adding a dopamine agonist.

journal_name

Pituitary

journal_title

Pituitary

authors

Molitch ME

doi

10.1007/s11102-008-0106-6

subject

Has Abstract

pub_date

2008-01-01 00:00:00

pages

209-18

issue

2

eissn

1386-341X

issn

1573-7403

journal_volume

11

pub_type

杂志文章,评审
  • Thyroid-stimulating hormone (thyrotropin)-secretion pituitary adenoma in an 8-year-old boy: case report.

    abstract::In this report, an extremely rare case of pediatric thyrotropin-secreting pituitary macroadenoma (TSHoma) is described. An 8-year-old boy, complaining of unsteady gait, was suspected of endocrinopathy because of emaciation and muscle weakness of the legs. Endocrinological work-up established a diagnosis of hyperthyroi...

    journal_title:Pituitary

    pub_type: 杂志文章

    doi:10.1007/s11102-010-0275-y

    authors: Nakayama Y,Jinguji S,Kumakura S,Nagasaki K,Natsumeda M,Yoneoka Y,Saito T,Fujii Y

    更新日期:2012-03-01 00:00:00

  • Can tissue biomarkers reliably predict the biological behavior of craniopharyngiomas? A comprehensive overview.

    abstract:BACKGROUND:The growing interest in the molecular and genetic alterations of craniopharyngiomas (CPs) is embodied in recent studies revealing insights into the CP tumorigenesis and identifying novel molecular pathways amenable of targeted therapies. The actual impact of this new information, however, remains inconclusiv...

    journal_title:Pituitary

    pub_type: 杂志文章,评审

    doi:10.1007/s11102-018-0890-6

    authors: Prieto R,Pascual JM

    更新日期:2018-08-01 00:00:00

  • Management and consequences of postoperative fluctuations in plasma sodium concentration after pediatric brain tumor surgery in the sellar region: a national cohort analysis.

    abstract:PURPOSE:Severe fluctuations in plasma sodium concentration and plasma osmolarity, including central diabetes insipidus (CDI), may have significant influence on postoperative morbidity and mortality after pediatric brain tumor surgery.The aim of this study was to describe the frequency, severity and neurological consequ...

    journal_title:Pituitary

    pub_type: 杂志文章

    doi:10.1007/s11102-018-0886-2

    authors: Kruis RWJ,Schouten-van Meeteren AYN,Finken MJJ,Oostdijk W,van Trotsenburg ASP,Boot AM,Claahsen-van der Grinten HL,van Lindert EJ,Han KS,Hoving EW,Michiels EMC,van Santen HM

    更新日期:2018-08-01 00:00:00

  • Gamma knife stereotactic radiosurgery for drug resistant or intolerant invasive prolactinomas.

    abstract::We evaluated the efficacy of Gamma knife stereotactic radiosurgery (GKSR) as an adjunctive management modality for patients with drug resistant or intolerant cavernous sinus invasive prolactinomas. Twenty-two patients with cavernous sinus invasive prolactinoma underwent GKSR between 1994 and 2009. Thirteen patients we...

    journal_title:Pituitary

    pub_type: 杂志文章

    doi:10.1007/s11102-012-0376-x

    authors: Liu X,Kano H,Kondziolka D,Park KJ,Iyer A,Shin S,Niranjan A,Flickinger JC,Lunsford LD

    更新日期:2013-03-01 00:00:00

  • The effect of somatostatin analogs and acromegaly on the upper gastrointestinal system.

    abstract:PURPOSE:To evaluate the effects of somatostatin analogs and disease activity status on the upper gastrointestinal system in patients with acromegaly. METHODS:One hundred eighty-one patients with acromegaly were retrospectively assessed. The demographic, biochemical, pathologic, and radiologic data of the patients were...

    journal_title:Pituitary

    pub_type: 杂志文章

    doi:10.1007/s11102-020-01095-3

    authors: Sahin S,Icli TB,Durcan E,Sulu C,Ozkaya HM,Hatemi AI,Kadioglu P

    更新日期:2020-10-19 00:00:00

  • GH deficiency in cancer survivors in the transition age: diagnosis and therapy.

    abstract:BACKGROUND:Survival rates among childhood cancer survivors (CCSs) have significantly risen in the last 40 years due to substantial improvements in treatment protocols. However, this improvement has brought with it serious late effects that frequently involve the endocrine system. Of the endocrine disorders, GH deficien...

    journal_title:Pituitary

    pub_type: 杂志文章,评审

    doi:10.1007/s11102-020-01052-0

    authors: Sbardella E,Crocco M,Feola T,Papa F,Puliani G,Gianfrilli D,Isidori AM,Grossman AB

    更新日期:2020-08-01 00:00:00

  • Cushing's disease.

    abstract::Cushing's disease, i.e., pituitary ACTH-secreting adenoma causing excess glucocorticoid secretion, is a rare disease with significant mortality and morbidity. Timely diagnosis and appropriate treatment can alter the course of the disease and are therefore mandatory. First step of the diagnostic work-up is the endogeno...

    journal_title:Pituitary

    pub_type: 杂志文章,评审

    doi:10.1007/s11102-006-0407-6

    authors: De Martin M,Pecori Giraldi F,Cavagnini F

    更新日期:2006-01-01 00:00:00

  • Aerosolisation in endonasal endoscopic pituitary surgery.

    abstract:PURPOSE:To determine the particle size, concentration, airborne duration and spread during endoscopic endonasal pituitary surgery in actual patients in a theatre setting. METHODS:This observational study recruited a convenience sample of three patients. Procedures were performed in a positive pressure operating room. ...

    journal_title:Pituitary

    pub_type: 杂志文章

    doi:10.1007/s11102-021-01125-8

    authors: Dhillon RS,Nguyen LV,Rowin WA,Humphries RS,Kevin K,Ward JD,Yule A,Phan TD,Zhao YC,Wynne D,McNeill PM,Hutchins N,Scott DA

    更新日期:2021-01-19 00:00:00

  • Overview of vascular complications of pituitary surgery with special emphasis on unexpected abnormality.

    abstract::Arterial bleeding during transsphenoidal surgery for pituitary adenoma is known complication. This usually happens due to rupture of intracavernous carotid or delayed hemorrhage due to the carotico-cavernous fistula and/or pseudoaneurysm. There is also evidence that cavernous carotid aneurysms may occur with pituitary...

    journal_title:Pituitary

    pub_type: 杂志文章,评审

    doi:10.1007/s11102-009-0198-7

    authors: Berker M,Aghayev K,Saatci I,Palaoğlu S,Onerci M

    更新日期:2010-06-01 00:00:00

  • Clinical picture and the treatment of TBI-induced hypopituitarism.

    abstract::Traumatic brain injury (TBI) is an important public health problem with an increasing incidence in the last years. Relatively few cases are fatal; most individuals will survive and, in the long-term, the sequalae of TBI will include neuroendocrine dysfunctions with a much higher frequency than previously suspected. Pa...

    journal_title:Pituitary

    pub_type: 杂志文章,评审

    doi:10.1007/s11102-019-00956-w

    authors: Caputo M,Mele C,Prodam F,Marzullo P,Aimaretti G

    更新日期:2019-06-01 00:00:00

  • Moderate dose cranial radiotherapy causes central adrenal insufficiency in long-term survivors of childhood leukaemia.

    abstract::Acute lymphoblastic leukaemia (ALL) is the most common childhood malignancy. The survival rate in the Scandinavian countries is now around 85 %. ALL patients treated with cranial radiotherapy (CRT) are at risk for growth hormone deficiency (GHD), but little is known about other pituitary insufficiencies, e.g. ACTH. Ad...

    journal_title:Pituitary

    pub_type: 杂志文章

    doi:10.1007/s11102-012-0459-8

    authors: Follin C,Wiebe T,Moëll C,Erfurth EM

    更新日期:2014-02-01 00:00:00

  • Management of recurrent pituitary cysts with pituitary-nasal drain.

    abstract::Pituitary cysts are usually craniopharyngiomas or remnants of Rathke's cleft. Histologically craniopharyngiomas are lined by stratified squamous epithelium whereas Rathke's cleft cysts are lined by cuboidal or columnar epithelium. The management of pituitary cysts remains difficult because of the risks associated with...

    journal_title:Pituitary

    pub_type: 杂志文章

    doi:10.1023/a:1025373715860

    authors: Dashora U,Mathias D,James A,Zammit-Maempel I,Perros P

    更新日期:2002-01-01 00:00:00

  • Pathology of prolactinomas: any predictive value?

    abstract::Lactotroph adenomas, also called prolactinomas and prolactin-secreting adenomas, constitute nearly 80% of functioning pituitary tumors and about 30-50% of all adenomas in the clinical practice. Lactotroph adenomas occur in the general population at a prevalence of 45/100,000, are more common in women, but also involve...

    journal_title:Pituitary

    pub_type: 杂志文章,评审

    doi:10.1007/s11102-019-00997-1

    authors: Lopes MBS

    更新日期:2020-02-01 00:00:00

  • Proteomics and transcriptomics analyses of secretagogin down-regulation in human non-functional pituitary adenomas.

    abstract::In order to explore the presence of, and the potential role of, secretagogin in human pituitary adenomas, an analytical strategy that integrated comparative proteomics and comparative transcriptomics was used to detect the protein and the mRNA expression, respectively, of secretagogin in human non-functional pituitary...

    journal_title:Pituitary

    pub_type: 杂志文章

    doi:10.1023/b:pitu.0000023426.99808.40

    authors: Zhan X,Evans CO,Oyesiku NM,Desiderio DM

    更新日期:2003-01-01 00:00:00

  • Suprasellar pituitary adenomas: a 10-year experience in a single tertiary medical center and a literature review.

    abstract:BACKGROUND:Suprasellar pituitary adenomas (SPAs) are a special type of pituitary adenoma. Although dozens of SPA cases have been reported, the exact definition and the characteristics of SPA have not been exhaustively discussed before. METHODS:In a retrospective electronic medical records review, 13 patients with SPA ...

    journal_title:Pituitary

    pub_type: 杂志文章

    doi:10.1007/s11102-020-01043-1

    authors: Zhu J,Wang Z,Zhang Y,Liu J,Li X,Deng K,Lu L,Yao Y

    更新日期:2020-08-01 00:00:00

  • Be careful... She has a pituitary gland in her nose.

    abstract::In this case report we describe a 38 year-old-female with galactorrhea several months after the birth of an anencephalic child. She had hyperpolactemia and imaging of the pituitary gland revealed a midline defect and a nasopharyngeal mass compatible with a meningo-(hypophyso-) encephalocele and possibly an ectopic ter...

    journal_title:Pituitary

    pub_type: 杂志文章

    doi:10.1007/s11102-011-0320-5

    authors: Rabelink NM,Lips P,Castelijns JA

    更新日期:2012-12-01 00:00:00

  • The metabolic consequences of thyroxine replacement in adult hypopituitary patients.

    abstract::The metabolic consequences of thyroxine replacement in patients with central hypothyroidism (CH) need to be evaluated. The aim was to examine the outcome of thyroxine replacement in CH. Adult hypopituitary patients (n = 1595) with and without CH from KIMS (Pfizer International Metabolic Database) were studied before a...

    journal_title:Pituitary

    pub_type: 杂志文章

    doi:10.1007/s11102-011-0356-6

    authors: Filipsson Nyström H,Feldt-Rasmussen U,Kourides I,Popovic V,Koltowska-Häggström M,Jonsson B,Johannsson G

    更新日期:2012-12-01 00:00:00

  • Primary central nervous system lymphoma mimicking pituitary apoplexy: case report.

    abstract::Lymphoma involving the pituitary gland is very rare and usually results from metastatic spread of systemic lymphoma. We present a case of primary central nervous system (CNS) large B cell lymphoma that manifested as pituitary apoplexy. A 45-year-old woman presented with headache, and then rapidly developed a third ner...

    journal_title:Pituitary

    pub_type: 杂志文章

    doi:10.1007/s11102-008-0084-8

    authors: Quintero Wolfe S,Hood B,Barker J,Benveniste RJ

    更新日期:2009-01-01 00:00:00

  • A case of lymphocytic infundibuloneurohypophysitis: histophathological studies.

    abstract::A 57-year-old woman presented with 2-year history of polyuria and polydipsia. Hormonal studies revealed almost normal anterior pituitary function and central diabetes insipidus. Magnetic resonance imaging showed thickening of the pituitary stalk and enlargement of the neurohypophysis without high intensity of the post...

    journal_title:Pituitary

    pub_type: 杂志文章

    doi:10.1023/a:1009914711287

    authors: Waki K,Yamada S,Ozawa Y,Seki K,Endo Y

    更新日期:1999-05-01 00:00:00

  • Leptin after IGF-I generation test in a patient with hypopituitarism and myotonic dystrophy disease.

    abstract::A 54-years-old woman diagnosed of myotonic dystrophy (MyD) with past medical history of massive postpartum haemorrhage at age 28 and panhypopituitarism was studied. BMI and body composition were determined and we determined baseline serum IGF-I, IGFBP3, insulin and leptin levels and after the IGF-I generation test per...

    journal_title:Pituitary

    pub_type: 杂志文章

    doi:10.1023/a:1009984505312

    authors: Gómez JM,Martínez-Matos JA

    更新日期:1999-01-01 00:00:00

  • Hematologic neoplasias and acromegaly.

    abstract::We report a 59-year-old acromegalic woman, who presented with generalized bone pain, weakness, fatigue and foamy urine, who was found to have multiple myeloma (MM); and a 60-year-old acromegalic woman with dizziness, vomiting and abdominal pain, high blood pressure and splenomegaly that was posteriorly diagnosed as ha...

    journal_title:Pituitary

    pub_type: 杂志文章

    doi:10.1007/s11102-009-0176-0

    authors: Barbosa FR,Vieira Neto L,Lima GA,Wildemberg LE,Portugal R,Gadelha MR

    更新日期:2011-12-01 00:00:00

  • Clinical characteristics of acromegalic patients with empty sella and their outcomes following transsphenoidal surgery.

    abstract:PURPOSE:To analyze the clinical characteristics of acromegalic patients with empty sella (ES, herniation of the subarachnoid space within the sella turcica) and the impact of ES on transsphenoidal surgery in such patients. METHODS:Seventy-eight patients, newly diagnosed with acromegaly who underwent transsphenoidal su...

    journal_title:Pituitary

    pub_type: 杂志文章

    doi:10.1007/s11102-017-0798-6

    authors: Sasagawa Y,Hayashi Y,Tachibana O,Oishi M,Fukui I,Iizuka H,Nakada M

    更新日期:2017-08-01 00:00:00

  • Sella turcica: an anatomical, endocrinological, and historical perspective.

    abstract:INTRODUCTION:The sphenoid bone has a superior depression called the sella turcica, Latin for "Turkish saddle," where the pituitary gland is found. The availability of modern radiological imaging techniques has replaced plain radiography of the sella turcica in the investigation of hypothalamo-pituitary abnormalities. H...

    journal_title:Pituitary

    pub_type: 历史文章,杂志文章,评审

    doi:10.1007/s11102-014-0609-2

    authors: Tekiner H,Acer N,Kelestimur F

    更新日期:2015-08-01 00:00:00

  • Pituitary tuberculosis mimicking idiopathic granulomatous hypophysitis.

    abstract::An unusual case of tubercular granulomatous hypophysitis is reported. A sellar mass diagnosed as pituitary adenoma in MRI, showed non-caseating granulomas, glandular destruction and fibrosis in histology. Stain for acid-fast bacilli (AFB) were negative and the case was misdiagnosed as Idiopathic Granulomatous hypophys...

    journal_title:Pituitary

    pub_type: 杂志文章

    doi:10.1007/s11102-007-0068-0

    authors: Husain N,Husain M,Rao P

    更新日期:2008-01-01 00:00:00

  • The extended, transnasal, transsphenoidal approach for anterior skull base meningioma: considerations in patient selection.

    abstract:PURPOSE:In this study, we set out to define our institutional criteria for patient eligibility for transsphenoidal resection of parasellar meningiomas, and to report our experience with extended transnasal approaches for these lesions. We aimed to discuss the important considerations of patient selection and risk strat...

    journal_title:Pituitary

    pub_type: 杂志文章

    doi:10.1007/s11102-017-0818-6

    authors: Castlen JP,Cote DJ,Zaidi HA,Laws ER Jr

    更新日期:2017-10-01 00:00:00

  • The genetic background of acromegaly.

    abstract::Acromegaly is caused by a somatotropinoma in the vast majority of the cases. These are monoclonal tumors that can occur sporadically or rarely in a familial setting. In the last few years, novel familial syndromes have been described and recent studies explored the landscape of somatic mutations in sporadic somatotrop...

    journal_title:Pituitary

    pub_type: 杂志文章,评审

    doi:10.1007/s11102-017-0789-7

    authors: Gadelha MR,Kasuki L,Korbonits M

    更新日期:2017-02-01 00:00:00

  • Importance of cannulated prolactin test in the definition of hyperprolactinaemia.

    abstract:PURPOSE:Recent guidelines suggest that a single prolactin measurement is adequate to confirm hyperprolactinaemia. This may lead to unnecessary investigation of artefactual hyperprolactinaemia. Prolactin measurement drawn from an indwelling cannula after rest removes stress as a confounding variable. The objective was t...

    journal_title:Pituitary

    pub_type: 杂志文章

    doi:10.1007/s11102-014-0576-7

    authors: Whyte MB,Pramodh S,Srikugan L,Gilbert JA,Miell JP,Sherwood RA,McGregor AM,Aylwin SJ

    更新日期:2015-06-01 00:00:00

  • Predictors of endoscopic transsphenoidal surgery outcome in acromegaly: patient and tumor characteristics evaluated by magnetic resonance imaging.

    abstract::The availability of various first-line treatment modalities for acromegaly and evolving surgical techniques emphasize the need for accurately defined predictors of surgical outcome. We retrospectively analysed the outcome of 30 patients with acromegaly after initial endoscopic transsphenoidal surgery in two university...

    journal_title:Pituitary

    pub_type: 杂志文章

    doi:10.1007/s11102-012-0395-7

    authors: van Bunderen CC,van Varsseveld NC,Baayen JC,van Furth WR,Aliaga ES,Hazewinkel MJ,Majoie CB,Freling NJ,Lips P,Fliers E,Bisschop PH,Drent ML

    更新日期:2013-06-01 00:00:00

  • Cushing's disease, pseudo-Cushing states and the dexamethasone test: a historical and critical review.

    abstract::The dexamethasone (DXM) test has been widely used for diagnosing Cushing's disease (CD). The purpose of this paper is to review its diagnostic merit based on calculation of data extracted from earlier publications. Studies presenting individual values for patients with CD and normal subjects were identified through Pu...

    journal_title:Pituitary

    pub_type: 杂志文章,评审

    doi:10.1007/s11102-013-0509-x

    authors: Lindholm J

    更新日期:2014-08-01 00:00:00

  • Measurement of oxidative stress and endothelial dysfunction in patients with hypopituitarism and severe deficiency adult growth hormone deficiency.

    abstract::Patients with adult GH deficiency (AGHD) have a high cardiovascular risk and probably an alteration of the oxidative balance, although evidence is lacking. To evaluate the presence of endothelial dysfunction and oxidative stress in patients with AGHD. Biochemical parameters of oxidative stress and endothelial dysfunct...

    journal_title:Pituitary

    pub_type: 杂志文章

    doi:10.1007/s11102-011-0374-4

    authors: González-Duarte D,Madrazo-Atutxa A,Soto-Moreno A,Leal-Cerro A

    更新日期:2012-12-01 00:00:00