Abstract:
:Rheumatoid arthritis (RA) has historically been a disabling and life-threatening disease. Features include joint pain, stiffness and swelling, joint damage, fatigue, loss of function, and loss of employment. Recent advances in treatment, particularly the use of conventional disease-modifying therapies earlier and in combination, and the advent of biological therapies, ensures that modern rheumatologists expect to help patient attain remission, with advantages of early presentation and effective therapies used in a "treatment to target" strategy. Adherence to UK National Institute for Health and Clinical Excellence guidance for RA, including early identification of disease, early and aggressive use of disease-modifying antirheumatic therapies, in combination or with biological agents, allows for much better disease control and perhaps remission. Delays to diagnosis will therefore become increasingly important, and the necessity for accurate diagnosis becomes crucial. The strategy of tight disease control may be more important than the contribution of individual drugs, even biological agents. Future prospects include the use of better outcome measures to define remission, better prediction of outcome, and thus better targeting of therapies. There is an urgent need for better individualized prognostic predictors. We must not forget the management of patients with pain owing to damage from advanced disease. Rheumatologists and radiologists must work together to appreciate the opportunities for patients from a greater understanding of disease measurement.
journal_name
Semin Musculoskelet Radioljournal_title
Seminars in musculoskeletal radiologyauthors
Kay LJdoi
10.1055/s-0032-1329878subject
Has Abstractpub_date
2012-11-01 00:00:00pages
353-9issue
5eissn
1089-7860issn
1098-898Xjournal_volume
16pub_type
杂志文章abstract::Ligamentous injuries of the elbow are common in sports. The diagnosis is usually based on a combination of the assessment of the mechanism of injury during the sporting activity and physical examination. Imaging with radiographs and MR imaging has an important diagnostic role, particularly when the clinical presentati...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-0033-1360666
更新日期:2013-11-01 00:00:00
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journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-0034-1396762
更新日期:2015-02-01 00:00:00
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journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章
doi:10.1055/s-0040-1721378
更新日期:2020-12-01 00:00:00
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journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-0038-1645862
更新日期:2018-07-01 00:00:00
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journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章
doi:10.1055/s-2001-15662
更新日期:2001-06-01 00:00:00
abstract::The vast majority of soft tissue masses are benign. Benign lesions such as superficial lipomas and ganglia are by far the most common soft tissue masses and can be readily identified and excluded on ultrasound (US). US is an ideal triaging tool for superficial soft tissue masses. Compared with magnetic resonance imagi...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章
doi:10.1055/s-0039-3402060
更新日期:2020-04-01 00:00:00
abstract::Ulnar-sided wrist pain is one of the most common symptoms in athletes of baseball, racket sports, golf, and wrestling where there is frequent use of the hands as well as in soccer and running, where hand use is minimal. Compared with all wrist injuries, ulnar-sided wrist injury is a relatively serious condition for at...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-0032-1327006
更新日期:2012-09-01 00:00:00
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journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
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更新日期:2018-02-01 00:00:00
abstract::Dentists and oral and maxillofacial radiologists have used periapical, occlusal, panoramic, and cephalometric radiographs for many years for diagnosing dental anomalies, especially before orthodontic or surgical treatment. Cone beam computed tomography was developed in recent years especially for the dental and maxill...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章
doi:10.1055/s-0040-1709210
更新日期:2020-10-01 00:00:00
abstract::During the last 12 years, tumoral calcinosis (TC) has become an entity that is better understood by radiologists, clinicians, and pathologists. Several aspects of TC are well documented by the scientific community, although the most important, etiology, remains an enigma. As a consequence, the treatment of TC continue...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
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更新日期:2002-12-01 00:00:00
abstract::Three-dimensional (3D) turbo-spin echo (TSE) sequences have outgrown the stage of mere sequence optimization and by now are clinically applicable. Image blurring and acquisition times have been reduced, and contrast for T1-, T2-, and moderately T2-weighted (or intermediate-weighted) fat-suppressed variants has been op...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-0035-1563732
更新日期:2015-09-01 00:00:00
abstract::Osteoid osteomas are small painful benign bone tumors that can be effectively treated by radiofrequency ablation (RFA) in most situations. This article briefly reviews the typical imaging findings of osteoid osteomas and the RFA technique used to treat them at our institution. It concludes with several examples of ost...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-0036-1594280
更新日期:2016-11-01 00:00:00
abstract::Osteoarthritis (OA) is the most common joint disease in the United States. The prevalence of OA is rising due to an aging population and increasing rates of obesity. Magnetic resonance imaging (MRI) allows an incomparable noninvasive assessment of all joint structures. Irreversible and progressive degradation of the a...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-0039-1695720
更新日期:2019-10-01 00:00:00
abstract::Biostatistics is an essential component in most original research studies in imaging. In this article we discuss five key statistical concepts for study design and analyses in modern imaging research: statistical hypothesis testing, particularly focusing on noninferiority studies; imaging outcomes especially when ther...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-0036-1597252
更新日期:2017-02-01 00:00:00
abstract::The treatment of articular cartilage injuries remains a challenge because cartilage has a limited capacity for spontaneous repair. Over the past decade, a number of surgical interventions have been developed to produce a durable repair. This article reviews the available treatment options, including their indications,...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-2001-19044
更新日期:2001-12-01 00:00:00
abstract::Balancing mobility and stability, the biomechanics of the shoulder provides optimal use of the thumb and hand. More than a glenohumeral joint, the shoulder complex consists of four joints and numerous muscles and ligaments. Injuries to the shoulder result from overuse, extremes of motion, and excessive forces. This re...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-2003-41081
更新日期:2003-03-01 00:00:00
abstract::Bisphosphonates have been widely used in the treatment of osteoporosis with well-documented long-term efficacy and safety, particularly in postmenopausal patients. But over the past decade, low-energy atypical subtrochanteric and proximal diaphyseal femoral fractures have emerged as an unexpected complication of prolo...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-0036-1593766
更新日期:2016-09-01 00:00:00
abstract::Over the last 2 decades, the definition of pathomechanical concepts that link osseous deformities to chondrolabral damage and expose young and active patients to the risk of early osteoarthritis has led to a tremendous increase in the number of joint-preserving surgeries performed. The rise in arthroscopic procedures ...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-0039-1678729
更新日期:2019-06-01 00:00:00
abstract::Congenital upper limb malformations represent complex pathologies because of their varied clinical presentations, imaging features, and etiologies. They can be divided into (1) failure of formation with transverse, intercalary, and longitudinal (preaxial, postaxial, and mesoaxial) deficiencies, (2) failure of differen...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-0032-1311766
更新日期:2012-04-01 00:00:00
abstract::The magnetic susceptibility artifact created by the hardware that is a mainstay of today's surgical techniques can complicate magnetic resonance (MR) imaging of the postoperative spine. This article reviews the physical principles that underlie production of the magnetic susceptibility artifact, as well as the imaging...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-2000-9344
更新日期:2000-01-01 00:00:00
abstract::Entrapment and compressive neuropathies are frequent clinical conditions occurring about the elbow. In most instances clinical and electromyograhic evaluation are adequate for patient management, but in some cases further evaluation with imaging techniques is required. Magnetic resonance imaging (MRI) has been shown t...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章
doi:10.1055/s-2008-1080098
更新日期:1998-01-01 00:00:00
abstract::The differential diagnosis for a midfoot or forefoot mass or mass-like abnormality includes several common benign and malignant pathologies. Evaluation with imaging can often provide a diagnosis, or at least several likely etiologies, and guide management. Determining if a mass is cystic or solid with ultrasound or MR...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-0036-1581118
更新日期:2016-04-01 00:00:00
abstract::Musculoskeletal (MSK) radiology plays a crucial role in the diagnosis and management of MSK disorders and has rapidly expanded in tandem with advances in technology and improved access to imaging. Although anatomical imaging remains the mainstay of MSK radiology, significant progress has been made in functional and mo...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章
doi:10.1055/s-0038-1673623
更新日期:2018-11-01 00:00:00
abstract::31Phosphorus (31P) magnetic resonance spectroscopy (MRS) is well suited for gathering data on skeletal muscle energetics in vivo. The technique has evolved to the point where it has become an important tool in the study of the pathophysiology both of rare primary disorders of muscle such as the mitochondrial myopathie...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-2000-13172
更新日期:2000-01-01 00:00:00
abstract::This article reviews the basics of image-guided intervention of musculoskeletal neoplasms. Image-guided procedures are playing an ever-increasing role in the diagnosis, staging, and treatment of musculoskeletal tumors. The successful handling of these lesions necessitates a multidisciplinary approach, with the radiolo...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-0033-1343096
更新日期:2013-04-01 00:00:00
abstract::Body composition entails the measurement of muscle and fat mass in the body and has been shown to impact clinical outcomes in various aspects of human health. As a result, the need is growing for reliable and efficient noninvasive tools to measure body composition. Traditional methods of estimating body composition, a...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-0039-3400267
更新日期:2020-02-01 00:00:00
abstract::Foot pain and disability may curtail the performance of simple routine tasks, work-related duties, and athletic activities. Disorders of the plantar fascia are commonly encountered in the diagnostic evaluation of subcalcaneal heel pain. The approach to imaging the ankle and foot has undergone significant amendment wit...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章
doi:10.1055/s-2002-32357
更新日期:2002-06-01 00:00:00
abstract::Fortunately, serious injuries to the cervical spine in athletes are rare. Most injuries are self-limited and related to sprains and strains. Although radiographs may be used to screen for fractures, potentially serious soft-tissue injuries require additional diagnostic techniques. In these cases, advanced imaging with...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
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更新日期:2004-03-01 00:00:00
abstract::Magnetic resonance imaging (MRI) is widely used in the clinical setting as well as for research applications. Since its inception, technical development has broadly progressed as a response to challenges in both the clinical and research settings. Higher magnetic field strength and advances in hardware and software ha...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章,评审
doi:10.1055/s-0037-1599209
更新日期:2017-04-01 00:00:00
abstract::Radiographic interpretation of pediatric elbow trauma presents a daunting task for both the radiologist and treating orthopaedic surgeon. Proper radiographic diagnosis and appropriate intervention requires a thorough understanding and appreciation of developmental anatomy. As the pediatric elbow matures, it transition...
journal_title:Seminars in musculoskeletal radiology
pub_type: 杂志文章
doi:10.1055/s-2007-984412
更新日期:2007-03-01 00:00:00