Abstract：
:Subject-specific FE-models of human long bones have to predict mechanical parameters with sufficient accuracy to be applicable in a clinical setting. One of the main aspects in subject-specific FE-models of bones regarding accuracy is the modeling of the material inhomogeneity. The goal of this study was therefore to develop FE-models of human femurs and investigate if a single validated density-elasticity relationship can be used for subject specific finite element analyses of human long bones, when the task is to predict the bone's mechanical response to load. To this aim, 23 human cadaver femurs were tested in axial compression with a load of 1000 N. Strains, local displacements, and axial bone stiffness were determined. Subject-specific FE-models were developed for each bone based on quantitative CT-scans. Three different density-elasticity relationships were retrieved from the literature, and were implemented in the FE-models. The predicted mechanical values depended largely on the used equation. The most reasonable equation showed a mean error of -11% in strain prediction, a mean error of -23% in local displacement prediction, and a mean error of +23% in axial stiffness prediction. The scatter of the predictions was very low in all three categories of measurements with a 1.96 standard deviation of about 30% to the mean errors. In conclusion, a framework for subject-specific FE-models was developed that was able to predict surface strains and bone deformation with good accuracy by using a single density-elasticity relationship. However, it was also found that the most appropriate density-elasticity relationship was specimen-specific.
journal_name
Med Eng Physjournal_title
Medical engineering & physicsauthors
Eberle S,Göttlinger M,Augat Pdoi
10.1016/j.medengphy.2012.08.022subject
Has Abstractpub_date
2013-07-01 00:00:00pages
875-83issue
7eissn
1350-4533issn
1873-4030pii
S1350-4533(12)00249-4journal_volume
35pub_type
杂志文章abstract：:Balance impairment is critical for many patient groups such as those with neural and musculoskeletal disorders and also the elderly. Accurate and objective assessment of balance performance has led to the development of several indices based on the measurement of the center of pressure. In this study, a robotic device...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2020.07.006
更新日期：2020-09-01 00:00:00
abstract：:In vivo bone behaviour predictions with respect to altered loading conditions, implants, and endoprostheses are highly desirable to avoid untoward effects such as implant loosening and breakage. This knowledge does not relate only to the result but also to the mechanisms of bone adaptation and bone growth. Since bone ...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/1350-4533(94)90014-0
更新日期：1994-01-01 00:00:00
abstract：:Failures of proximal femoral nails that treat unstable femoral fractures have been reported. In this communication, a finite element model to include a proximal femoral nail within a fractured femur was used to carry out preliminary investigations into configurations of single or double lag screws. The effects of the ...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/s1350-4533(00)00081-3
更新日期：2000-11-01 00:00:00
abstract：:The second-order difference plot, as a modified Poincaré plot, is one of the important approaches for assessing the dynamics of heart rate variability. However, corresponding quantitative analysis methods are relatively limited. Based on the second-order difference plot, we propose a novel method, called the multi-sca...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2014.09.015
更新日期：2014-12-01 00:00:00
abstract：:Comprehensive evaluation of results obtained using acoustic and contact microphones in screening for laryngeal disorders through analysis of sustained phonation is the main objective of this study. Aiming to obtain a versatile characterization of voice samples recorded using microphones of both types, 14 different set...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2014.12.005
更新日期：2015-02-01 00:00:00
abstract：:Somatosensory evoked potential (SEP) testing has been widely applied to diagnosis of various neurological disorders. However, SEP recorded using surface electrodes is buried in noises, which makes the signal-to-noise ratio (SNR) very poor. Conventional averaging method usually requires up to thousands of raw SEP input...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2004.09.007
更新日期：2005-04-01 00:00:00
abstract：:Tripolar systems have been implanted to reduce the risk of recurrent dislocation. However, there is little known about the dynamic behavior of tripolar hip endoprostheses under daily life conditions and achieved joint stability. Hence, the objective of this biomechanical study was to examine the in vivo dynamics and d...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2013.09.007
更新日期：2014-01-01 00:00:00
abstract：:Postural control deficits are the most disabling aspects of Parkinson's disease (PD), resulting in decreased mobility and functional independence. The aim of this study was to assess the postural control stability, revealed by variables based on the centre of pressure (CoP), in individuals with PD while performing a s...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2015.08.011
更新日期：2015-11-01 00:00:00
abstract：:Sequentially drilling multiple holes in bone is used clinically for surface preparation to aid in fusion of a joint, typically under non-irrigated conditions. Drilling induces a significant amount of heat and accumulates after multiple passes, which can result in thermal osteonecrosis and various complications. To und...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2015.06.002
更新日期：2015-09-01 00:00:00
abstract：:CT data has been widely used in the finite element modeling of bone. It can provide useful information on the geometrical topology and material properties of bone. Based on CT data, the assignment of bone material properties to finite element meshes is a fundamental step in the model generation. Most work done in this...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2005.06.003
更新日期：2006-04-01 00:00:00
abstract：:Scoliosis is a 3D deformity of the spine and rib cage. Extensive validation of 3D reconstruction methods of the spine from biplanar radiography has already been published. In this article, we propose a novel method to reconstruct the rib cage, using the same biplanar views as for the 3D reconstruction of the spine, to...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2013.06.002
更新日期：2013-11-01 00:00:00
abstract：:During reconstructive surgery of the face, one side may be used as a template for the other, exploiting assumed bilateral facial symmetry. The best method to calculate this plane, however, is debated. A new semi-automatic technique for calculating the symmetry plane of the facial skeleton is presented here that uses s...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2013.06.006
更新日期：2013-12-01 00:00:00
abstract：:Dynamic models of the human trunk have been extensively used to investigate the biomechanics of lower back pain and postural instability in different populations. Despite their diverse applications, previous models rely on intrinsic upper body segment parameters (UBSP), e.g., each segment's mass-inertia characteristic...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2010.09.008
更新日期：2011-01-01 00:00:00
abstract：:We investigated whether automatic control of a hand grasp neuroprosthesis by means of signals from natural sensors in the skin of the index finger can mimic the natural control of grasp force in an important task of daily living, namely eating. We designed a simulated eating task with the same ratio of rest and activi...
journal_title：Medical engineering & physics
pub_type： 临床试验,杂志文章
doi：10.1016/j.medengphy.2004.03.002
更新日期：2004-07-01 00:00:00
abstract：:Small spaces make collision-free turns difficult for wheelchair users. Contrary to basic kinematic wheelchair modelling and not considered previously by engineers; when wheelchairs turn in small spaces, could lateral drift (sideways slipping) increase the risk of collisions with surrounding structures such as walls an...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2020.11.012
更新日期：2021-01-01 00:00:00
abstract：:We introduce a novel dual-switch control paradigm based on the simultaneous measurement of frontalis muscle mechanomyography (MMG) and vocalizations (humming) using a single contact microphone attached to the forehead. Vibrations of the face and skull during vocalization are manifested as periodic high-frequency compo...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2010.06.003
更新日期：2010-10-01 00:00:00
abstract：:The measurement of wrist active range of motion (ROM) is essential for determining the progress of hand functional recovery, which can provide insight into quantitative improvements and enable effective monitoring during hand rehabilitation. Compared with manual methods, which depend on the experience of the therapist...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2019.07.003
更新日期：2019-09-01 00:00:00
abstract：:T2 mapping is a powerful noninvasive technique providing quantitative biological information of the inherent tissue properties. However, its clinical usage is limited due to the relative long scanning time. This paper proposed a novel model-based method to address this problem. Typically, we directly estimated the rel...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2014.06.002
更新日期：2014-11-01 00:00:00
abstract：:The internal carotid artery (ICA) has been proposed as an alternative site to the middle cerebral artery (MCA) to measure dynamic cerebral autoregulation (dCA) using transcranial Doppler ultrasound (TCD). Our aim was to test the inter-operator reproducibility of dCA assessment in the ICA and the effect of interaction ...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2016.03.007
更新日期：2016-07-01 00:00:00
abstract：:Our main goal was to test various impedance methods for measuring body composition in adolescents with anorexia nervosa (AN) during refeeding therapy. A specific objective was to compare the information provided by a foot-to-foot impedancemeter (FFI) with that supplied by a medical multifrequency impedancemeter and by...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2007.09.005
更新日期：2008-07-01 00:00:00
abstract：:The mean value and standard deviation of localization error for the stereo imaging systems are derived based on probability theory. Compared with the maximum error analysis method used in our previous study, the new approach yields more informative and precise results as the guidance for X-ray imaging system design an...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/s1350-4533(01)00084-4
更新日期：2001-10-01 00:00:00
abstract：:Electromyography (EMG) has been widely used for the assessment of musculoskeletal functions and the control of electrical prostheses, which make use of the EMG signal generated by the contraction of the residual muscles. In spite of the successful applications of EMG in different fields, it has some inherent limitatio...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2005.07.012
更新日期：2006-06-01 00:00:00
abstract：:Stent implantation has become a widely accepted endovascular intervention for the treatment of stenosed arteries. This minimally invasive technique has shown excellent results in unbranched arteries. However, stenting bifurcation lesions remains a challenge in coronary intervention as it is associated with a lower suc...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2008.11.013
更新日期：2009-05-01 00:00:00
abstract：:A field-usable sleepiness tester could reduce sleepiness related accidents. 15 subjects' postural steadiness was measured with a Nintendo(®) Wii Fit balance board every hour for 24 h. Body sway was quantified with complexity index, CI, and the correlation between CI and alertness predicted by a three-process model of ...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2013.08.007
更新日期：2013-12-01 00:00:00
abstract：:Functional spinal units (FSUs) are frequently used for in vitro mechanical testing. This approach assumes that the mechanical behavior of the FSUs is equivalent to the mechanics of these segments within the intact spine. The purpose of this study was to determine whether normal spinal mechanics are compromised in FSU ...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/s1350-4533(02)00152-2
更新日期：2003-04-01 00:00:00
abstract：OBJECTIVE:Joint space narrowing is an important feature of progressive joint damage and functional impairment in rheumatoid arthritis (RA). Methods to provide a continuous measurement of joint space width have not been adopted in research or clinical settings. High-resolution peripheral quantitative computed tomography...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2013.04.003
更新日期：2013-10-01 00:00:00
abstract：:The impeller blood pump with its simplicity has many advantages compared with the diaphragm pump, but the nonpulsatile property has limited its applications. To make the impeller pump pulsatile, many investigations have been made in vain because of resulting haemolysis. The author has succeeded in producing a pulsatil...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/1350-4533(95)00010-0
更新日期：1996-01-01 00:00:00
abstract：:A decrease in bone density at the hip or spine has been shown to increase the risk of fracture. A limitation of the bone mineral density (BMD) measurement is that it provides only a measure of a bone sample's average density when projected onto a 2D surface. Effectively, what determines bone fracture is whether an app...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2011.08.008
更新日期：2012-05-01 00:00:00
abstract：:The value of compliance of disposable elements such as infusion lines and syringes can significantly affect the performance characteristics of infusion devices. In a technique used to determine the compliance of infusion lines, the item under test is placed in a semi sealed water filled enclosure and the volume of flu...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2014.07.016
更新日期：2014-11-01 00:00:00
abstract：BACKGROUND AND AIMS OF THE STUDY:Mechanical heart valves (MHV) are widely used to replace dysfunctional and failed heart valves. The bileaflet MHV design is very popular due to its superior hemodynamics. Since their introduction in 1977, the hemodynamics of bileaflet prostheses has been extensively studied. In this stu...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2005.03.013
更新日期：2006-03-01 00:00:00
