PAR-1 polymorphisms and risk of Helicobacter pylori-related gastric cancer in a Chinese population.

abstract：AIM:To report our experience on implementation and preliminary results of a decision-making model based on the recommendations of an Interdisciplinary Oncological Care Group developed for the management of colorectal cancer. PATIENTS AND METHODS:The multidisciplinary team identified a reference guideline using apprais...

journal_title：Anticancer research

authors： Genovesi D,Mazzilli L,Trignani M,DI Tommaso M,Nuzzo A,Biondi E,Tinari N,Martino MT,Innocenti P,DI Sebastiano P,Mazzola L,Lanci C,Neri M,Laterza F,Marino M,Ferrini G,Spadaccini A,Filippone A,DI Giandomenico E,Marulli

更新日期：2014-05-01 00:00:00

abstract：:MUC1 (DF3 antigen) is a member of a family of high molecular weight glycoproteins. Recent studies have demonstrated that MUC1 is expressed in tumors of various human organs and may function as an anti-adhesion molecule that inhibits cell-to-cell adhesion, inducing tumor metastasis. However, expression patterns of MUC1...

journal_title：Anticancer research

authors： Kijima H,Chino O,Oshiba G,Tanaka H,Kenmochi T,Kise Y,Shimada H,Abe Y,Tokunaga T,Yamazaki H,Nakamura M,Tanaka M,Makuuchi H,Ueyama Y

更新日期：2001-03-01 00:00:00

abstract：:A pharmacokinetic study on cis-(glycolato-O,O)/ (4R,5R)-4,5-bis(aminomethyl)-1,3-dioxolane-2-spiro-1'- cyclohexane]platinum(II) (SKI 2032R) was performed in dogs. A single dose of 2.0 mg/kg of SKI 2032R was administered i.v. bolus to three beagle dogs. Plasma samples were analyzed for platinum by flameless atomic abso...

journal_title：Anticancer research

authors： Kim DK,Cho YB,Kim HT,Kim TS,Kim KH,Hong WS

更新日期：1996-05-01 00:00:00

abstract：:Herein we report on a case of synchronous large gastrointestinal stromal tumor (GIST) and adenocarcinoma of the stomach treated with radical surgery following neoadjuvant therapy with imatinib mesylate. A 58-year-old man was referred to our hospital with a large mass in the peritoneal cavity. Abdominal computed tomogr...

journal_title：Anticancer research

authors： Namikawa T,Munekage E,Munekage M,Maeda M,Yatabe T,Kitagawa H,Sakamoto K,Obatake M,Kobayashi M,Hanazaki K

更新日期：2016-04-01 00:00:00

abstract：:We examined the expression of survivin using immunohistochemistry in 102 cases of laryngeal squamous cell carcinoma (LSCC). Overall, 65.7% (67 out of 102) of tumors were positive for survivin expression and significantly associated with tumor site, poor differentiation, tumor size, lymph node metastasis and advanced s...

journal_title：Anticancer research

authors： Dong Y,Sui L,Watanabe Y,Sugimoto K,Tokuda M

更新日期：2002-07-01 00:00:00

abstract：:P-glycoprotein (P-gp) actively pumps out a number of anticancer drugs, such as epirubicin, from tumor cells. P-gp is also expressed in the small intestine under normal physiological conditions. Inhibition of intestinal P-gp function using MDR reversing agents may enhance the oral bioavailability of some chemotherapeut...

journal_title：Anticancer research

authors： Lo YL,Hsu CY,Huang JD

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND/AIM:We evaluated the efficacy and safety of carbon-ion radiotherapy (CIRT) alone for Stage III non-small-cell lung cancer (NSCLC). PATIENTS AND METHODS:Data of 65 patients (median age=73 years) with Stage III NSCLC who underwent CIRT alone in the QST Hospital, Chiba, Japan, between 1997 and 2015 were retros...

journal_title：Anticancer research

authors： Anzai M,Yamamoto N,Hayashi K,Nakajima M,Nomoto A,Ogawa K,Tsuji H

更新日期：2020-01-01 00:00:00

abstract：:In this study, a protein kinase C inhibitor, H-7, was found to potentiate the antiproliferative effects of difluoromethyl ornithine (DFMO), inhibitor of the polyamine biosynthesis, on NIH 3T3 and 3T3/SV40 cells in culture. Incubation of the cells with DFMO inhibited the cell growth, whereas the addition of polyamine s...

journal_title：Anticancer research

authors： Khan NA,Havouis R,Quemener V,Moulinoux JP

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND:Pure or metaplastic squamous cell carcinoma (SCC) of the breast is a rare entity with an unclear pathogeny and aggressive clinical behaviour. An attempt was made to characterize its differential immunohistochemical and biological profile. PATIENTS AND METHODS:Twenty-seven cases of SCC (pure or not) of the b...

journal_title：Anticancer research

authors： Grenier J,Soria JC,Mathieu MC,Andre F,Abdelmoula S,Velasco V,Morat L,Besse B,Dunant A,Spielmann M,Delaloge S

更新日期：2007-01-01 00:00:00

abstract：:In experimental and clinical phase II trials GnRH agonists were shown to possess antitumor activity in ovarian cancer. The outcome of prostatic cancer was also improved experimentally by a combination of cytostatic chemotherapy and GnRH analogs. Encouraged by these results, we administered micro-encapsulated triptorel...

journal_title：Anticancer research

authors： Medl M,Peters-Engel C,Fuchs G,Leodolter S

更新日期：1993-11-01 00:00:00

abstract：AIM:To elucidate the behavior of 1 phosphatidylinositol 4,5 bisphosphate (PIP2) 5 phosphatase (PIP2 5-Pase, EC 3.1.3.36) and 1 phosphatidylinositol 4 phosphate (PIP) 4-phosphatase (PIP 4-Pase) in cancer cells, the steady state activities of PIP2 5-Pase and PIP 4-Pase were determined in the particulate fractions of rat ...

journal_title：Anticancer research

authors： Yang H,Shen F,Weber G

更新日期：1999-11-01 00:00:00

abstract：:1-(phenylmethyl)-4,7,10-tris-[(4'methylphenyl)-sulfonyl]-1,4,7, 10-tetraazacyclododecane proved to possess potent in vivo antineoplastic and in vitro cytotoxicity in murine and human tissue cultured cells. In Tmolt3 leukemic cells 1-(phenylmethyl)-4,7,10-tris-[(4'methylphenyl)sulfonyl]-1,4,7, 10-tetraazacyclododecane ...

journal_title：Anticancer research

authors： Hall IH,Elkins AL,Karthikeyan S,Spielvogel BF

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND:The aim of this study was to determine the progression-free survival (PFS) and toxicity associated with adjuvant administration of carboplatin and pemetrexed for completely resected patients with stage IB, II and IIIA non-small cell lung cancer (NSCLC). PATIENTS AND METHODS:Forty-five eligible NSCLC patient...

journal_title：Anticancer research

authors： Karapanagiotou EM,Boura PG,Papamichalis G,Konstantinou M,Sepsas E,Chamalakis G,Simsiris P,Gkiozos I,Syrigos KN

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:Gingival squamous cell carcinoma (SCC) cells frequently invade mandibular bone, and this destruction is associated with a worse prognosis. However, the relationship between bone destruction and associated factors is unclear. In this study, the role and diagnostic utility of transforming growth factor-beta (T...

journal_title：Anticancer research

authors： Goda T,Shimo T,Yoshihama Y,Hassan NM,Ibaragi S,Kurio N,Okui T,Honami T,Kishimoto K,Sasaki A

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:Prostate cancer treated with androgen ablation eventually becomes resistant. Because the androgen receptor (AR) signaling axis affects disease progression, AR coactivator molecules could provide clinical prognostic value. This study investigates the association between AR coactivator molecules and clinical o...

journal_title：Anticancer research

authors： Mori R,Wang Q,Quek ML,Tarabolous C,Cheung E,Ye W,Groshen S,Hawes D,Togo S,Shimada H,Danenberg KD,Danenberg PV,Pinski JK

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:The description of the different forms of circulating PSA has opened a new strategy in the diagnosis of prostate cancer. The aim of our study was to assess the diagnostic potential of PSA and the PSA fractions in the diagnosis of benign prostate hyperplasia (BPH) and prostate cancer. PATIENTS AND METHODS:We...

journal_title：Anticancer research

authors： Filella X,Alcover J,Corral JM,Molina R,Beardo P,Ballesta AM

更新日期：2001-09-01 00:00:00

abstract：:Screening for hereditary tumours provides a basis for secondary prevention. In 1985, the Foundation for the Detection of Hereditary Tumours was established in The Netherlands to coordinate screening in families with hereditary tumours. In the initial period of four years a large number of families were collected. Regi...

journal_title：Anticancer research

authors： Vasen HF,Griffioen G,Lips CJ,Struyvenberg A,van Slooten EA

更新日期：1990-03-01 00:00:00

abstract：:Four patients with colorectal cancer after pelvic irradiation for gynaecological malignancies are reported. The interval between irradiation and the diagnosis of colorectal cancer was 15-28 years. Histological findings of radiation proctocolitis adjacent to the cancer were observed in all specimens. Ki-67 immunohistol...

journal_title：Anticancer research

authors： Tsunoda A,Shibusawa M,Kawamura M,Marumori T,Kusano M,Ohta H

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND/AIM:Although reckoned necessary for survival benefit, neoadjuvant chemotherapy (NAC) of gastric cancer (GC) patients has so far provided questionable results. Consequently, searching for new and clearer systems of response to NAC, post-NAC re-evaluation and prognostic prediction appears essential. The purpos...

journal_title：Anticancer research

authors： Virgilio E,Giarnieri E,Giovagnoli MR,Montagnini M,Proietti A,D'Urso R,Fegiz A,Mercantini P,Balducci G,Cavallini M

更新日期：2019-02-01 00:00:00

abstract：:We have previously shown that L-glutamic acid gamma-monohydroxamate (GAH) exhibits an antitumor activity, both in vitro and in vivo. In this report we explore the selective cytotoxicity of GAH in vitro by comparing the survival of tumor and normal cells. GAH exerts an irreversible delayed effect with tumoral cells and...

journal_title：Anticancer research

authors： Thomasset N,Chabanas A,Tournaire R,Malley S,Navarro C,Lawrence JJ,Doré JF,Vila J

更新日期：1993-09-01 00:00:00

abstract：AIM:The current study aimed to determine the prognostic significance of thrombocytosis in patients with colorectal cancer (CRC) by a meta-analysis of the literature. PATIENTS AND METHODS:The meta-analysis followed the 2009 guidelines of Preferred Reporting Items for Systematic Reviews and Meta-Analyses. A systematic l...

journal_title：Anticancer research

authors： Gu D,Szallasi A

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND/AIM:Several epidemiological studies have reported the chemopreventive potential of biochanin A, in cancer development and progression. We investigated the anticancer potential of combination of biochanin A and temozolomide against U-87 MG and T98 G [glioblastoma multiforme (GBM)] cells. MATERIALS AND METHOD...

journal_title：Anticancer research

authors： Desai V,Jain A,Shaghaghi H,Summer R,Lai JCK,Bhushan A

更新日期：2019-01-01 00:00:00

abstract：AIM:We aimed to clarify the prognostic significance of HER2 positivity in advanced gastric cancer. PATIENTS AND METHODS:The cohort included patients with initially metastatic or recurrent gastric cancer treated with first-line modified FOLFOX-6. The HER2 status was analyzed according to modified scoring criteria speci...

journal_title：Anticancer research

authors： Kim JW,Im SA,Kim M,Cha Y,Lee KH,Keam B,Kim MA,Han SW,Oh DY,Kim TY,Kim WH,Bang YJ

更新日期：2012-04-01 00:00:00

abstract：:The most widely-known anti-tumor drugs often induce marked immunosuppression which can give rise to one or more sepses. Anti-infection measures immediately applied can sometimes prove largely ineffective or even useless, the patient dying not as a result of the spread of the tumour but as a direct consequence of oppor...

journal_title：Anticancer research

authors： Castelli M,Baggio G,Ruberto AI,Malagoli M,Casolari C,Rossi T,Galatulas I

更新日期：1997-11-01 00:00:00

abstract：:Combined treatment of interleukin-2 (IL-2), 5-fluorouracil (5-FU) and mitomycin C (MMC) is reported to be effective against hepatic metastasis of colon carcinoma. To clarify this modality, we investigated lymphokine activated killer (LAK) activity of human peripheral lymphocytes on colon cancer cell lines by 51Cr rele...

journal_title：Anticancer research

authors： Ishihara M,Kubota T,Watanabe M,Kawano Y,Narai S,Yasui N,Otani Y,Teramoto T,Kitajima M

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND/AIM:In patients with soft tissue sarcoma (STS), distinguishing small metastatic pulmonary nodules from benign ones remains difficult. This study aimed to determine the accuracy of 18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) in detecting pulmonary metastasis and identi...

journal_title：Anticancer research

authors： Hagi T,Nakamura T,Sugino Y,Matsubara T,Asanuma K,Sudo A

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND/AIM:We undertook a case-control and a case-case study to examine the possible association of p53 codon72 polymorphism with the breast cancer risk and resistance to anthracycline-based chemotherapy. PATIENTS AND METHODS:Case-control study: This study enrolled 175 patients with breast cancer treated at the Sa...

journal_title：Anticancer research

authors： Arfaoui A,Douik H,Kablouti G,Chaaben AB,Handiri N,Zid Z,Ouni N,Zouiouch F,Ayari F,Mamoughli T,Bouassida J,Abazza H,Harzallaha L,Guemira F

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND/AIM:The toxicity of the proteasome inhibitor MG132 was tested alone and combined either with the topoisomerase I inhibitor topotecan or the topoisomerase II inhibitor etoposide against a panel of 18 cell lines representing six pediatric tumor types. MATERIALS AND METHODS:MG132, topotecan, etoposide and thei...

journal_title：Anticancer research

authors： Destanovic E,Boos J,Lanvers-Kaminsky C

更新日期：2018-07-01 00:00:00

abstract：:A plethora of contradictory research surrounds vitamin D and its influence on health and disease. This may, in part, result from analytical difficulties with regard to measuring vitamin D metabolites in serum. Indeed, variation exists between analytical techniques and assays used for the determination of serum 25-hydr...

journal_title：Anticancer research

authors： Stokes CS,Lammert F,Volmer DA

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Matrix metalloproteinase 9 (MMP-9) plays an important role in cancer invasion and metastasis. The relationship between serum MMP-9 levels and clinicopathological factors in gastric cancer patients is not clear. MATERIALS AND METHODS:Preoperative serum was obtained from 170 patients who had undergone gastrec...

journal_title：Anticancer research

authors： Shen KH,Chi CW,Lo SS,Kao HL,Lui WY,Wu CW

更新日期：2000-03-01 00:00:00