Paravertebral blockade for day-case breast augmentation: a randomized clinical trial.

Abstract:

BACKGROUND:Bilateral breast augmentation is an increasingly popular day-case procedure. Local infiltration with sedation is routinely used for its ease of application compared with the more complex and potentially riskier paravertebral blockade (PVB). We hypothesized that ropivacaine injected by experienced anesthesia providers into the paravertebral space as a PVB was more effective than ropivacaine injected by the operating surgeon (plastic surgeon) directly into the zone of surgical dissection. METHODS:Forty female patients who were ASA physical status I or II and undergoing bilateral subpectoral cosmetic breast augmentation were recruited for participation in a prospective, randomized, single-blind study. Patients were randomized to 1 of 2 groups: ropivacaine via PVB, or surgical infiltration of ropivacaine. In both groups, the surgeon was asked to infiltrate the appropriate area with either saline (PVB group) or ropivacaine (local infiltration group). Both groups were sedated with propofol, titrated to effect. The plastic surgeon was blinded to the solution injected. Data collected included demographic characteristics, intraoperative cooperation scores, recovery room postoperative nausea and vomiting, analgesia use, and visual analog scale pain scores. All patients were asked to complete a preoperative anxiety and quality of recovery questionnaire and to record their pain scores and analgesia requirements on discharge. The outcome measures were (i) intraoperative patient cooperation as assessed by the plastic surgeon, (ii) propofol requirement, (iii) postoperative pain, and (iv) quality of recovery. RESULTS:Forty patients completed the study. PVB improved intraoperative cooperation (significance of difference P < 0.001, WMWodds = 6.69 with 95% 1-sided confidence interval CI ≥2.85), reduced propofol requirement (significance of difference P = 0.005, WMWodds = 0.35, CI <0.69), and decreased average postoperative pain in the home environment (significance of difference P = 0.007, WMWodds = 0.38, CI <0.73). There were no PVB complications. Only patients from the surgical infiltration group required rescue analgesics (30%, significance of difference = 0.01). CONCLUSIONS:In a limited number of patients, we found that PVB is superior to direct surgical infiltration of ropivacaine for bilateral breast augmentation in same-day surgery. These advantages need to be balanced against the potential risks of PVB, especially in an office setting.

journal_name

Anesth Analg

journal_title

Anesthesia and analgesia

authors

Gardiner S,Rudkin G,Cooter R,Field J,Bond M

doi

10.1213/ANE.0b013e318264ba33

subject

Has Abstract

pub_date

2012-11-01 00:00:00

pages

1053-9

issue

5

eissn

0003-2999

issn

1526-7598

pii

ANE.0b013e318264ba33

journal_volume

115

pub_type

杂志文章,随机对照试验
  • Nonlinear heart rate variability analysis may predict atrial fibrillation after coronary artery bypass grafting.

    abstract:BACKGROUND:Heart rate variability might predict arrhythmias after coronary artery bypass grafting. METHODS:Off-line processing of 10-min electrocardiogram recordings of consecutive patients provided R-R intervals for time domain, frequency domain, Poincaré, and point correlation analyses and subsequent association wit...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/01.ane.0000239330.45658.76

    authors: Chamchad D,Djaiani G,Jung HJ,Nakhamchik L,Carroll J,Horrow JC

    更新日期:2006-11-01 00:00:00

  • A comparison of two epidural alpha 2-agonists, guanfacine and clonidine, in regard to duration of antinociception, and ventilatory and hemodynamic effects in goats.

    abstract::Epidural clonidine produces analgesia in humans with acute and chronic pain. Its use is limited because of short-lasting analgesia, hemodynamic depression, sedation, and respiratory depression. Intrathecal guanfacine has a longer duration of action than intrathecal clonidine. The present study compares these two drugs...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:

    authors: Smith BD,Baudendistel LJ,Gibbons JJ,Schweiss JF

    更新日期:1992-05-01 00:00:00

  • Assessment of vaporizer performance in low-flow and closed-circuit anesthesia.

    abstract::The performance of five of the most commonly used halothane vaporizers and three enflurane vaporizers was tested under conditions encountered in low-flow and closed-circuit anesthesia. Anesthetic gas concentrations were measured continuously with a mass spectrometer connected to a circle system. The results indicated ...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:

    authors: Lin CY

    更新日期:1980-05-01 00:00:00

  • Succinylcholine-vecuronium (Org NC 45) sequence for cesarean section.

    abstract::Vecuronium (Org NC 45) was used in 27 parturients undergoing elective cesarean section under general anesthesia. One of the parturients had a twin pregnancy. Neuromuscular transmission was assessed clinically by stimulating the ulnar nerve and observing the contraction of the fingers. An initial bolus of 0.05 mg . kg-...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:

    authors: Baraka A,Noueihed R,Sinno H,Wakid N,Agoston S

    更新日期:1983-10-01 00:00:00

  • S(+)-ketamine as an analgesic adjunct reduces opioid consumption after cardiac surgery.

    abstract::There are no studies evaluating S(+)-ketamine for pain management after sternotomy. In this prospective, randomized, double-blind, placebo-controlled clinical trial, we evaluated the efficacy and feasibility of S(+)-ketamine as an adjunctive analgesic after cardiac surgery. Ninety patients scheduled for elective coron...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1213/01.ANE.0000133913.07342.B9

    authors: Lahtinen P,Kokki H,Hakala T,Hynynen M

    更新日期:2004-11-01 00:00:00

  • Adenosine-induced flow arrest to facilitate intracranial aneurysm clip ligation does not worsen neurologic outcome.

    abstract:BACKGROUND:When temporary arterial occlusion of the parent artery is difficult for anatomical reasons, or when inadvertent aneurysmal rupture occurs during surgical dissection, adenosine administration can be used to produce flow arrest and brief, profound systemic hypotension that can facilitate intracranial aneurysm ...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/ANE.0b013e3182a6d31b

    authors: Bebawy JF,Zeeni C,Sharma S,Kim ES,DeWood MS,Hemmer LB,Ramaiah VK,Bendok BR,Koht A,Gupta DK

    更新日期:2013-11-01 00:00:00

  • Postoperative Myocardial Injury in Middle-Aged and Elderly Patients Following Curative Resection of Esophageal Cancer With Aggressive or Standard Body Temperature Management: A Randomized Controlled Trial.

    abstract:BACKGROUND:Risk of intraoperative hypothermia is relatively high in middle-aged and elderly patients undergoing curative resection of esophageal cancer, which may cause myocardial ischemia during the early postoperative period. The objective of this study was to compare aggressive or standard body temperature managemen...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1213/ANE.0000000000004022

    authors: Zhang Z,Xu M,Wu D,Zhang X,Wu J

    更新日期:2019-08-01 00:00:00

  • The volatile anesthetic isoflurane inhibits the histamine-induced Ca2+ influx in primary human endothelial cells.

    abstract:UNLABELLED:Although isoflurane is a known vasodilator, the mechanism of isoflurane-induced vasodilation is not clear. One of the most important systems in this context is the nitric oxide (NO)-mediated vasodilation. The activity of this system is regulated by the agonist-induced Ca(2+) influx rather than Ca(2+) release...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/01.ane.0000068826.97781.ce

    authors: Tas PW,Stöbetael C,Roewer N

    更新日期:2003-08-01 00:00:00

  • A survey of anesthesiologists' views of operating room recycling.

    abstract:BACKGROUND:Operating rooms contribute significantly to the increasing volumes and costs of hospital waste. Little is known, however, about doctors' views of hospital waste recycling despite their potential influence in improving recycling programs. We surveyed the waste recycling views held by anesthesiologists in Aust...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/ANE.0b013e31824d273d

    authors: McGain F,White S,Mossenson S,Kayak E,Story D

    更新日期:2012-05-01 00:00:00

  • The contribution of the coronary concentrations of propofol to its cardiovascular effects in anesthetized sheep.

    abstract:UNLABELLED:Linking physiological pharmacokinetic models to models of the cardiovascular system requires knowledge of the sites in the body that mediate a drug's cardiovascular effects. We examined the role of the coronary concentrations of propofol. Nine sheep anesthetized with isoflurane (2%) were instrumented acutely...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/01.ane.0000060561.16583.a7

    authors: Zheng D,Upton RN,Martinez AM

    更新日期:2003-06-01 00:00:00

  • The effects of milrinone on platelets in patients undergoing cardiac surgery.

    abstract::Although amrinone produces thrombocytopenia, no information is available regarding the acute effects of milrinone on platelets. Therefore, we evaluated the effects of milrinone on platelet number and function in cardiac surgical patients. Twenty-seven patients were studied during cardiac surgery requiring cardiopulmon...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00000539-199507000-00009

    authors: Kikura M,Lee MK,Safon RA,Bailey JM,Levy JH

    更新日期:1995-07-01 00:00:00

  • Blood pressure, not cardiac output, determines blood loss during induced hypotension.

    abstract::Cardiac output characteristically decreases during trimethaphan infusion but is well maintained or increased during sodium nitroprusside infusion. We postulated that at similar levels of mean arterial pressure, sodium nitroprusside might be associated with greater blood loss than trimethaphan due to the increase in ca...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:

    authors: Sivarajan M,Amory DW,Everett GB,Buffington C

    更新日期:1980-03-01 00:00:00

  • Comparison of Intraoperative Sedation With Dexmedetomidine Versus Propofol on Acute Postoperative Pain in Total Knee Arthroplasty Under Spinal Anesthesia: A Randomized Trial.

    abstract:BACKGROUND:In patients undergoing total knee arthroplasty under spinal anesthesia, we compared the postoperative analgesic effect of intraoperative sedation with dexmedetomidine versus propofol. We hypothesized that sedation with dexmedetomidine would result in lower postoperative opioid analgesic consumption than with...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1213/ANE.0000000000003315

    authors: Shin HJ,Do SH,Lee JS,Kim TK,Na HS

    更新日期:2019-12-01 00:00:00

  • Right Ventricular Longitudinal Strain Is Depressed in a Bovine Model of Pulmonary Hypertension.

    abstract:BACKGROUND:Pulmonary hypertension and resulting right ventricular (RV) dysfunction are associated with significant perioperative morbidity and mortality. Although echocardiography permits real-time, noninvasive assessment of RV function, objective and comparative measures are underdeveloped, and appropriate animal mode...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/ANE.0000000000001215

    authors: Bartels K,Brown RD,Fox DL,Bull TM,Neary JM,Dorosz JL,Fonseca BM,Stenmark KR

    更新日期:2016-05-01 00:00:00

  • Propofol suppresses the cortical somatosensory evoked potential in rats.

    abstract:UNLABELLED:The dose-response curve for the effect of volatile anesthetics on the somatosensory evoked potential (SEP) is well described, but for propofol, the large dose segment of the curve is undefined. We describe the effect of increasing plasma concentrations of propofol on cortical SEPs in 18 rats. After surgical ...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/01.ane.0000090318.16879.a8

    authors: Logginidou HG,Li BH,Li DP,Lohmann JS,Schuler HG,DiVittore NA,Kreiser S,Cronin AJ

    更新日期:2003-12-01 00:00:00

  • Propofol anesthesia for children undergoing magnetic resonance imaging: a comparison with isoflurane, nitrous oxide, and a laryngeal mask airway.

    abstract:BACKGROUND:Both propofol infusions with oxygen delivered through nasal cannula and isoflurane/N2O (nitrous oxide) delivered via a laryngeal mask airway (LMA) are used to provide anesthesia for children undergoing magnetic resonance imaging scans. We compared the incidence of adverse events and perioperative physiologic...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1213/ANE.0000000000000504

    authors: Heard C,Harutunians M,Houck J,Joshi P,Johnson K,Lerman J

    更新日期:2015-01-01 00:00:00

  • Cyclosporine can increase isoflurane MAC.

    abstract:UNLABELLED:Previous reports indicate that cyclosporine increases sleeping time from barbiturate administration, and analgesia from fentanyl administration, suggesting a possible contribution of cyclosporine to anesthesia. Accordingly, we determined whether cyclosporine pretreatment decreases isoflurane MAC (the minimum...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1097/00000539-200210000-00025

    authors: Niemann CU,Stabernack C,Serkova N,Jacobsen W,Christians U,Eger EI 2nd

    更新日期:2002-10-01 00:00:00

  • An absorbable local anesthetic matrix provides several days of functional sciatic nerve blockade.

    abstract:BACKGROUND:Functional blockade of peripheral nerves is the primary objective of local anesthesia, and it is often desirable to have a persistent blockade, sustained throughout and beyond a surgical procedure. Current local anesthetics give effective analgesia for <8-12 h after a single bolus injection. We report on an ...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/ane.0b013e318193596a

    authors: Wang CF,Djalali AG,Gandhi A,Knaack D,De Girolami U,Strichartz G,Gerner P

    更新日期:2009-03-01 00:00:00

  • Intravenous administration of flurbiprofen does not affect cerebral blood flow velocity and cerebral oxygenation under isoflurane and propofol anesthesia.

    abstract:UNLABELLED:Flurbiprofen, a nonsteroidal antiinflammatory drug (NSAID), has been used to treat rheumatic and osteoarthritic pain and to reduce postoperative pain. Although other NSAIDs, such as indomethacin, reduce cerebral blood flow (CBF), the effect of flurbiprofen on CBF is unknown. In the present study, we investig...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1213/01.ane.0000099755.97885.3c

    authors: Yoshitani K,Kawaguchi M,Tatsumi K,Sasaoka N,Kurumatani N,Furuya H

    更新日期:2004-02-01 00:00:00

  • Multiwavelength pulse oximetry: theory for the future.

    abstract:BACKGROUND:As the use of pulse oximeters increases, the needs for higher performance and wider applicability of pulse oximetry have increased. To realize the full potential of pulse oximetry, it is indispensable to increase the number of optical wavelengths. To develop a multiwavelength oximetry system, a physical theo...

    journal_title:Anesthesia and analgesia

    pub_type: 历史文章,杂志文章

    doi:10.1213/01.ane.0000268716.07255.2b

    authors: Aoyagi T,Fuse M,Kobayashi N,Machida K,Miyasaka K

    更新日期:2007-12-01 00:00:00

  • Serum anticholinergic activity and postoperative cognitive dysfunction in elderly patients.

    abstract:BACKGROUND:Cerebral cholinergic transmission plays a key role in cognitive function, and anticholinergic drugs administered during the perioperative phase are a hypothetical cause of postoperative cognitive dysfunction (POCD). We hypothesized that a perioperative increase in serum anticholinergic activity (SAA) is asso...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章

    doi:10.1213/ANE.0000000000000390

    authors: Rossi A,Burkhart C,Dell-Kuster S,Pollock BG,Strebel SP,Monsch AU,Kern C,Steiner LA

    更新日期:2014-10-01 00:00:00

  • A Randomized Controlled Trial Comparing Two Multimodal Analgesic Techniques in Patients Predicted to Have Severe Pain After Cesarean Delivery.

    abstract:BACKGROUND:Improved pain control after cesarean delivery remains a challenging objective. Poorly treated acute pain following delivery is associated with an increased risk of chronic pain and depression. This study was conducted to determine whether the addition of systemic acetaminophen and an increased dose of intrat...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1213/ANE.0000000000000695

    authors: Booth JL,Harris LC,Eisenach JC,Pan PH

    更新日期:2016-04-01 00:00:00

  • Naloxone does not antagonize the analgesic effects of inhalation anesthetics.

    abstract::A previous demonstration that the ratio of analgesic to anesthetic endpoints is not constant across inhalation anesthetic agents implies that more than one mechanism of action may be operant in general anesthesia. We hypothesized that the endogenous opiate systems might account for this observed disparity in ratios. T...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:

    authors: Levine LL,Winter PM,Nemoto EM,Uram M,Lin MR

    更新日期:1986-04-01 00:00:00

  • The preemptive analgesic effect of rofecoxib after ambulatory arthroscopic knee surgery.

    abstract:UNLABELLED:Nonsteroidal antiinflammatory drugs (NSAIDs) provide effective postoperative analgesia after arthroscopic knee surgery. Some investigators have suggested that the preemptive administration of NSAIDs may reduce postoperative analgesic requirements and hypersensitivity. We evaluated the analgesic effect of adm...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00000539-200201000-00010

    authors: Reuben SS,Bhopatkar S,Maciolek H,Joshi W,Sklar J

    更新日期:2002-01-01 00:00:00

  • How to improve the performance of intraoperative risk models: an example with vital signs using the surgical apgar score.

    abstract:BACKGROUND:Computerized reviews of patient data promise to improve patient care through early and accurate identification of at-risk and well patients. The significance of sampling strategy for patient vital signs data is not known. In the instance of the surgical Apgar score (SAS), we hypothesized that larger sampling...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/ANE.0b013e3182a46d6d

    authors: Hyder JA,Kor DJ,Cima RR,Subramanian A

    更新日期:2013-12-01 00:00:00

  • A Contemporary Medicolegal Analysis of Outpatient Medication Management in Chronic Pain.

    abstract:BACKGROUND:Opioids are frequently used in chronic pain management but are associated with significant morbidity and mortality in some patient populations. An important avenue for identifying complications-including serious or rare complications-is the study of closed malpractice claims. The present study is intended to...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/ANE.0000000000002499

    authors: Abrecht CR,Brovman EY,Greenberg P,Song E,Rathmell JP,Urman RD

    更新日期:2017-11-01 00:00:00

  • Perioperative changes in blood pressure and heart rate.

    abstract::In order to evaluate the possible physiologic significance of intra- and postoperative hypotension, we monitored arterial blood pressure and heart rate continuously for 36 hr starting the night before and ending the morning after operation in 34 gynecologic patients. The lowest pressures that occurred during physiolog...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:

    authors: Berger JJ,Donchin M,Morgan LS,van der Aa J,Gravenstein JS

    更新日期:1984-07-01 00:00:00

  • Case report: neurological complications associated with epidural analgesia in children: a report of 4 cases of ambiguous etiologies.

    abstract::The safety and utility of pediatric epidural analgesia is well established, but the risk of permanent neurological injury is unknown and largely must be extrapolated from adult literature. In this article we present a series of 4 cases of longterm or permanent neurologic complications associated with epidural analgesi...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章

    doi:10.1213/ANE.0b013e31826918b6

    authors: Meyer MJ,Krane EJ,Goldschneider KR,Klein NJ

    更新日期:2012-12-01 00:00:00

  • A comparison of the costs and efficacy of ondansetron versus dolasetron for antiemetic prophylaxis.

    abstract:UNLABELLED:The optimal dose and timing of 5-HT(3) antagonist administration for prophylaxis against postoperative nausea and vomiting (PONV) remains controversial. Although 5-HT(3) antagonists seem to be most effective when administered near the end of surgery, there are no data on the comparative efficacy or costs ass...

    journal_title:Anesthesia and analgesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00000539-200006000-00017

    authors: Zarate E,Watcha MF,White PF,Klein KW,Sa Rego M,Stewart DG

    更新日期:2000-06-01 00:00:00

  • The efficacy of a resistive heating under-patient blanket versus a forced-air warming system: a randomized controlled trial.

    abstract:BACKGROUND:We compared temperature changes in patients undergoing hip replacement during warming with a resistive heating blanket or air-forced system. METHODS:Fifty-six patients were enrolled. Patients were randomly allocated to the "forced-air group" (forced-air system) or to the "heating-blanket group" (resistive h...

    journal_title:Anesthesia and analgesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1213/ane.0b013e31818e6199

    authors: Fanelli A,Danelli G,Ghisi D,Ortu A,Moschini E,Fanelli G

    更新日期:2009-01-01 00:00:00