Blood pressure, not cardiac output, determines blood loss during induced hypotension.

abstract：UNLABELLED:We evaluated the effect of the fresh gas flow (FGF) rate and the anesthetic technique on the ability to control the acute hyperdynamic response to a specific surgical stimulus during surgery in 90 consenting ASA physical status I-III patients undergoing lower abdominal procedures. After the administration of...

journal_title：Anesthesia and analgesia

authors： Avramov MN,Griffin JD,White PF

更新日期：1998-09-01 00:00:00

abstract：IMPLICATIONS:This case describes the impact of argatroban and off-pump coronary revascularization on hemostasis as assessed by conventional hemostatic measures and Thrombelastography in a patient with heparin-induced thrombocytopenia. ...

journal_title：Anesthesia and analgesia

authors： Kieta DR,McCammon AT,Holman WL,Nielsen VG

更新日期：2003-04-01 00:00:00

abstract：:Combinations of nonsteroidal antiinflammatory drugs (NSAIDs) and opioids are widespread in the management of pain, allowing better analgesia with reduced side effects. Cannabinoids are promising analgesic drugs that have pharmacological properties similar to those of opioids. However, the beneficial effects of cannabi...

journal_title：Anesthesia and analgesia

authors： Ulugöl A,Ozyigit F,Yesilyurt O,Dogrul A

更新日期：2006-02-01 00:00:00

abstract：:Sufentanil is a potent opioid that occasionally has been associated with hypotension. The mechanism behind this hypotension is unclear. We hypothesized that sufentanil had a direct effect on vascular smooth muscle to cause vasodilation. Sufentanil was infused into the brachial artery of 10 young, healthy volunteers at...

journal_title：Anesthesia and analgesia

authors： Ebert TJ,Ficke DJ,Arain SR,Holtz MN,Shankar H

更新日期：2005-12-01 00:00:00

abstract：:Acute respiratory distress syndrome (ARDS) is a significant cause of morbidity and mortality in the intensive care unit (ICU) and is characterized by lung epithelial and endothelial cell injury, with increased permeability of the alveolar-capillary membrane, leading to pulmonary edema, severe hypoxia, and difficulty w...

journal_title：Anesthesia and analgesia

authors： Lee LK,Medzikovic L,Eghbali M,Eltzschig HK,Yuan X

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Many new mechanical ventilation modes are proposed without any clinical evaluation. "Dual-controlled" modes, such as AutoFlow™, are supposed to improve patient- ventilator interfacing and could lead to fewer alarms. We performed a long-term clinical evaluation of the efficacy and safety of AutoFlow during as...

journal_title：Anesthesia and analgesia

authors： Lasocki S,Labat F,Plantefeve G,Desmard M,Mentec H

更新日期：2010-10-01 00:00:00

abstract：:We evaluated risk of heart block after cardiopulmonary by-pass (CPB) in patients with normal conduction undergoing coronary artery bypass grafting who chronically received calcium-entry blockers, beta-blockers, or combined therapy. Before CPB, calcium-entry blockers alone produced an increase in P-R intervals but no c...

journal_title：Anesthesia and analgesia

authors： Henling CE,Slogoff S,Kodali SV,Arlund C

更新日期：1984-05-01 00:00:00

abstract：UNLABELLED:The use of cerebral monitoring may improve the ability of anesthesiologists to titrate anesthetic drugs. However, there is controversy regarding the impact of the alleged anesthetic-sparing effects of cerebral monitoring on the recovery process and patient outcome. We designed this prospective double-blinded...

journal_title：Anesthesia and analgesia

authors： Recart A,Gasanova I,White PF,Thomas T,Ogunnaike B,Hamza M,Wang A

更新日期：2003-12-01 00:00:00

abstract：BACKGROUND:The pattern and magnitude of the hyperglycemic response to surgical stress, the added effect of low-dose steroids, and whether these differ in diabetics and nondiabetics remain unclear. We therefore tested 2 hypotheses: (1) that diabetics show a greater increase from preoperative to intraoperative glucose co...

journal_title：Anesthesia and analgesia

authors： Abdelmalak BB,Bonilla AM,Yang D,Chowdary HT,Gottlieb A,Lyden SP,Sessler DI

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:We compared temperature changes in patients undergoing hip replacement during warming with a resistive heating blanket or air-forced system. METHODS:Fifty-six patients were enrolled. Patients were randomly allocated to the "forced-air group" (forced-air system) or to the "heating-blanket group" (resistive h...

journal_title：Anesthesia and analgesia

authors： Fanelli A,Danelli G,Ghisi D,Ortu A,Moschini E,Fanelli G

更新日期：2009-01-01 00:00:00

abstract：UNLABELLED:Flurbiprofen, a nonsteroidal antiinflammatory drug (NSAID), has been used to treat rheumatic and osteoarthritic pain and to reduce postoperative pain. Although other NSAIDs, such as indomethacin, reduce cerebral blood flow (CBF), the effect of flurbiprofen on CBF is unknown. In the present study, we investig...

journal_title：Anesthesia and analgesia

authors： Yoshitani K,Kawaguchi M,Tatsumi K,Sasaoka N,Kurumatani N,Furuya H

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:Dosing subcutaneous (SC) unfractionated heparin (UFH) 3 times a day (TID) for deep venous thrombosis prophylaxis is used for patients in the United States undergoing nonorthopedic surgery. There is a lack of data on the risks of neuraxial techniques in patients receiving TID SC UFH; however, concerns have be...

journal_title：Anesthesia and analgesia

authors： Pace M,Koury K,Gulur P

更新日期：2014-11-01 00:00:00

abstract：IMPLICATIONS:Tizanidine was given systemically to rats with experimental postoperative pain. Partial pain relief was obtained, but the effect was not clinically significant. Although systemic tizanidine is effective in relieving experimental neuropathic pain, it is not as effective for postoperative pain. ...

journal_title：Anesthesia and analgesia

authors： Hord AH,Denson DD,Azevedo MI

更新日期：2001-11-01 00:00:00

abstract：:Hospitals rely on pagers and ordinary telephones to reach staff members in emergency situations. New telecommunication technologies such as General Packet Radio Service (GPRS), the third generation mobile phone system Universal Mobile Telecommunications System (UMTS), and Wireless Local Area Network (WLAN) might be ab...

journal_title：Anesthesia and analgesia

authors： Wallin MK,Marve T,Hakansson PK

更新日期：2005-11-01 00:00:00

abstract：:Lidocaine decreases the minimum alveolar concentration (MAC) of inhaled anesthetics and has been used clinically to reduce the requirements for other anesthetic drugs. In this study we examined the effects of lidocaine on isoflurane MAC in cats. Six cats were studied. In Experiment 1, the MAC of isoflurane was determi...

journal_title：Anesthesia and analgesia

authors： Pypendop BH,Ilkiw JE

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:The Perioperative Surgical Home (PSH) seeks to remedy the currently highly fragmented and expensive perioperative care in the United States. The 2 specific aims of this health services research study were to assess the association between the preoperative and postoperative elements of an initial PSH model an...

journal_title：Anesthesia and analgesia

authors： Vetter TR,Barman J,Hunter JM Jr,Jones KA,Pittet JF

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Intercostal nerve blocks with liposomal bupivacaine are commonly used for thoracic surgery pain management. However, dose scheduling is difficult because the pharmacokinetics of a single-dose intercostal injection of liposomal bupivacaine has never been investigated. The primary aim of this study was to asse...

journal_title：Anesthesia and analgesia

authors： Manson WC,Blank RS,Martin LW,Alpert SB,Dobrzanski TP,Schneider EB,Ratcliffe SJ,Durieux ME

更新日期：2020-12-01 00:00:00

abstract：UNLABELLED:Reductions in cerebral venous oxyhemoglobin saturation (SjO2) occur during the rewarming phase of hypothermic cardiopulmonary bypass (CPB). We prospectively investigated the effects of propofol on these reductions in SjO2 (SjO2 <50%). Fiberoptic jugular bulb catheters were inserted in 30 patients undergoing ...

journal_title：Anesthesia and analgesia

authors： Souter MJ,Andrews PJ,Alston RP

更新日期：1998-05-01 00:00:00

abstract：:In Japan, an ever-present problem in the preoperative evaluation of patients with ischemic heart disease is that although such evaluations are based on Western data, these data serve as the basis for determining perioperative risk in Japanese patients. To remedy this problem, the Cardiac Ischemia and Anesthesia Resear...

journal_title：Anesthesia and analgesia

authors： Seki M,Kashimoto S,Nagata O,Yoshioka H,Ishiguro T,Nishimura K,Honda O,Sakamoto A,Omi A,Ogihara Y,Fujimoto K,Iwade M,Yamada T,Nomura M,Takeda J

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:Isoflurane activates vascular adenosine triphosphate sensitive potassium (K(ATP)) channels, and may induce vasodilation. In the present study, we investigated whether hyperglycemia modifies isoflurane activation of vascular K(ATP) channel. METHODS:We used a cell-attached patch-clamp configuration to test th...

journal_title：Anesthesia and analgesia

authors： Kawano T,Tanaka K,Mawatari K,Oshita S,Takahashi A,Nakaya Y

更新日期：2008-03-01 00:00:00

abstract：:A low approach to the interscalene block (LISB) deposits local anesthetic farther caudad on the brachial plexus compared with the conventional interscalene block (ISB). We compared the efficacy of LISB and ISB in achieving anesthesia of the distal extremity in 254 patients having upper extremity surgery. The most freq...

journal_title：Anesthesia and analgesia

authors： Kim JH,Chen J,Bennett H,Lesser JB,Resta-Flarer F,Barczewska-Hillel A,Byrnes P,Santos AC

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Growing awareness of the negative impacts from the practice of health care on the environment and public health calls for the routine inclusion of life cycle criteria into the decision-making process of device selection. Here we present a life cycle assessment of 2 laryngeal mask airways (LMAs), a one-time-u...

journal_title：Anesthesia and analgesia

authors： Eckelman M,Mosher M,Gonzalez A,Sherman J

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:The arterial pulse oximeter, which was introduced clinically in the 1970s, is a convenient, useful, and now ubiquitous anesthesia monitor. Unfortunately, although percent saturation of arterial hemoglobin is, along with cardiac output and concentration of hemoglobin, one of 3 components of oxygen delivery, i...

journal_title：Anesthesia and analgesia

authors： Thiele RH,Tucker-Schwartz JM,Lu Y,Gillies GT,Durieux ME

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Pro- and anti-inflammatory cytokines (adipokines) associated with adipose tissue can modulate inflammatory processes and lead to systemic inflammatory conditions such as metabolic syndrome. In the present pilot study, we investigated 3 major adipokines (leptin, adiponectin, and resistin) and 2 nonspecific pr...

journal_title：Anesthesia and analgesia

authors： Hozumi J,Sumitani M,Nishizawa D,Nagashima M,Ikeda K,Abe H,Kato R,Kusakabe Y,Yamada Y,Japanese Translational Research-Cancer Pain Research Group.

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Statistical heterogeneity can increase the uncertainty of results and reduce the quality of evidence derived from systematic reviews. At present, it is uncertain what the major factors are that account for heterogeneity in meta-analyses of analgesic adjuncts. Therefore, the aim of this review was to identify...

journal_title：Anesthesia and analgesia

authors： Doleman B,Sutton AJ,Sherwin M,Lund JN,Williams JP

更新日期：2018-02-01 00:00:00

abstract：:To test the hypothesis that acute subarachnoid hemorrhage is associated with abnormal myocardial perfusion, we assessed myocardial blood flow with thallium scintigraphy in 19 patients with a confirmed subarachnoid hemorrhage and an abnormal electrocardiogram. A thallium scan was performed at the bedside of each patien...

journal_title：Anesthesia and analgesia

authors： Szabo MD,Crosby G,Hurford WE,Strauss HW

更新日期：1993-02-01 00:00:00

abstract：:Spine surgery has been growing rapidly as a neurosurgical operation, with an increase of 220% over a 15-year period. Intraoperative blood transfusion is a major outcome determinant of spine procedures. Various approaches, including pharmacologic and nonpharmacologic therapies, have been tested to decrease both intraop...

journal_title：Anesthesia and analgesia

authors： Willner D,Spennati V,Stohl S,Tosti G,Aloisio S,Bilotta F

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Even though current perception threshold (CPT) has been used for evaluating the effectiveness of sensory block in patients before surgery, its reliability under controlled conditions has not been investigated. Two independent investigations were performed. The primary objective of the first study was to dete...

journal_title：Anesthesia and analgesia

authors： Gaudreault F,Drolet P,Fallaha M,Varin F

更新日期：2015-03-01 00:00:00

abstract：:It remains questionable whether local anesthetics can interact with membrane lipids at clinically relevant concentrations to show the difference between enantiomers. We compared the effects of bupivacaine stereoisomers on biomimetic membranes containing cardiolipin and cholesterol. Bupivacaine interacted with the memb...

journal_title：Anesthesia and analgesia

authors： Tsuchiya H,Mizogami M

更新日期：2012-02-01 00:00:00

abstract：UNLABELLED:This study was designed to determine if, and to what extent, antithrombin III (AT) levels affect the response of the activated clotting time (ACT) to heparin in concentrations used during cardiac surgery, and to characterize the relationship between AT levels and markers of activation of coagulation during c...

journal_title：Anesthesia and analgesia

authors： Despotis GJ,Levine V,Joist JH,Joiner-Maier D,Spitznagel E

更新日期：1997-09-01 00:00:00