Home blood pressure recording in mild hypertension: value of distinguishing sustained from clinic hypertension and effect on diagnosis and treatment. Bath Health District Hypertension Study Group.

Abstract:

:To identify the prevalence and magnitude of clinic changes in blood pressure and determine their effects on the diagnosis and treatment of hypertension, 268 patients with a BP greater than or equal to 160/95 mmHg on three consecutive occasions (twice in the general practitioner's surgery and once in the hospital clinic) recorded a home BP series with an electronic sphygmomanometer. Of these patients, 114 had never received antihypertensive treatment and 154 were receiving treatment. On return to the hospital clinic (second clinic visit) the BP was measured independently by the patient and doctor using electronic and mercury sphygmomanometers respectively and compared with the mean BP of the home series. In some 80% of both untreated and treated patients the second clinic BP was higher than the mean BP of the home series and in some 40% of patients a clinic rise of greater than 20/10 mmHg was recorded. Clinic falls in BP occurred in some 20% of both untreated and treated patients, but averaged only 4/4 mmHg. Treatment decisions based on a mean diastolic blood pressure of greater than or equal to 95 mmHg in the home series resulted in antihypertensive treatment not being started in 38% of untreated patients and not increased in 31% or reduced in 16% of treated patients when treatment would have been started, increased or continued unchanged on the basis of the second clinic (fourth recorded) diastolic blood pressure of greater than or equal to 95 mmHg. A patient recorded home series provides a representative sample of BP which distinguishes patients with sustained hypertension from those with clinic hypertension and may help reduce the overdiagnosis and overtreatment of mild hypertension.

journal_name

J Hum Hypertens

authors

Hall CL,Higgs CM,Notarianni L

subject

Has Abstract

pub_date

1990-10-01 00:00:00

pages

501-7

issue

5

eissn

0950-9240

issn

1476-5527

journal_volume

4

pub_type

杂志文章
  • Increased membraneous calcium concentrations in primary hypertension: a causal link to pathogenesis?

    abstract:BACKGROUND:Disturbance in calcium metabolism has been suggested in the pathogenesis of hypertension, however, membrane calcium content in humans has not been studied in detail yet in primary hypertension. We compared plasma, intracellular and membrane calcium concentrations in erythrocytes of patients with essential hy...

    journal_title:Journal of human hypertension

    pub_type: 杂志文章

    doi:10.1038/sj.jhh.1001121

    authors: Kosch M,Hausberg M,Barenbrock M,Posadzy-Malaczynska A,Rahn KH,Kisters K

    更新日期:2001-01-01 00:00:00

  • Antihypertensive effect of valyl-tyrosine, a short chain peptide derived from sardine muscle hydrolyzate, on mild hypertensive subjects.

    abstract::The present study was conducted to determine whether Valyl-Tyrosine (VY) has an antihypertensive effect on high-normal blood pressure and mild essential hypertension, as well as spontaneous hypertensive rats (SHR). A randomised double-blind placebo-controlled study was carried out on 29 volunteers. A 100-ml drink cont...

    journal_title:Journal of human hypertension

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1038/sj.jhh.1001065

    authors: Kawasaki T,Seki E,Osajima K,Yoshida M,Asada K,Matsui T,Osajima Y

    更新日期:2000-08-01 00:00:00

  • The role of angiotensin II receptor antagonists in hypertension management: focus on candesartan cilexetil.

    abstract::The prevention and treatment of hypertension both from the viewpoint of individual patient care and in terms of population health presents a considerable challenge to the medical profession. To assist in meeting this challenge, various bodies have produced guidelines for the management of hypertension during the past ...

    journal_title:Journal of human hypertension

    pub_type: 杂志文章,评审

    doi:10.1038/sj.jhh.1001072

    authors: Mancia G,Grassi G

    更新日期:2000-10-01 00:00:00

  • Does the Hawksley random zero sphygmomanometer underestimate blood pressure, and by how much?

    abstract::The study objective was to compare blood pressure (BP) measurement by the Hawksley random-zero sphygmomanometer and the standard mercury sphygmomanometer. Comparison of simultaneous 'blind' BP measurements were made using the Hawksley random-zero sphygmomanometer and the standard mercury sphygmomanometer linked by a Y...

    journal_title:Journal of human hypertension

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Mackie A,Whincup P,McKinnon M

    更新日期:1995-05-01 00:00:00

  • The association between longitudinal trends of thyroid hormones levels and incident hypertension in a euthyroid population.

    abstract::Thyroid hormones, including free triiodothyronine (FT3), free thyroxine (FT4), have well-recognized effects on the cardiovascular system. However, the evidence is lacking regarding the relationship between repeated FT3, FT4, and thyroid-stimulating hormone (TSH) measurements and incident hypertension. The aim of this ...

    journal_title:Journal of human hypertension

    pub_type: 杂志文章

    doi:10.1038/s41371-020-00474-4

    authors: Wang Y,Gu Y,Zhang Q,Liu L,Meng G,Wu H,Zhang S,Zhang T,Wang X,Sun S,Wang X,Zhou M,Jia Q,Song K,Niu K

    更新日期:2021-01-18 00:00:00

  • Increased expression of miR-33a in monocytes from Mexican hypertensive patients in elevated carotid intima-media thickness.

    abstract::miR-33a has been described as a key regulator in the initiation and progression of atherosclerosis. However, its role in arterial hypertension (HTA) has not been elucidated. Therefore, the aim of this study was to determine the association between the expression of miR-33a (5p and 3p) and the carotid intima-media thic...

    journal_title:Journal of human hypertension

    pub_type: 杂志文章

    doi:10.1038/s41371-018-0102-x

    authors: Torres-Paz YE,Huesca-Gómez C,Sánchez-Muñoz F,Martínez-Alvarado R,Soto ME,Torres-Tamayo M,Fuentevilla-Álvarez G,Gamboa R

    更新日期:2018-10-01 00:00:00

  • Insertion/deletion polymorphism of the angiotensin-converting enzyme gene and loss of the insertion allele in aldosterone-producing adenoma.

    abstract::The genetic mechanisms responsible for the formation of adrenocortical adenomas which autonomously produce aldosterone are largely unknown. The adrenal renin-angiotensin system has been implicated in the pathophysiology of these tumours. Angiotensin-converting enzyme (ACE) catalyses the generation of angiotensin II, a...

    journal_title:Journal of human hypertension

    pub_type: 杂志文章

    doi:

    authors: Tunny TJ,Xu L,Richardson KA,Stowasser M,Gartside M,Gordon RD

    更新日期:1996-12-01 00:00:00

  • Fasting glucose and HbA1c levels as risk factors for the development of hypertension in Japanese individuals: Toranomon hospital health management center study 16 (TOPICS 16).

    abstract::We investigated the effect of elevated concentrations of fasting plasma glucose (FPG) or hemoglobin A1c (HbA1c) on the risk of development of hypertension among apparently healthy Japanese. Studied were 9584 individuals without known diabetes and hypertension. During a 5-year follow-up period, 1098 individuals develop...

    journal_title:Journal of human hypertension

    pub_type: 杂志文章

    doi:10.1038/jhh.2014.77

    authors: Heianza Y,Arase Y,Kodama S,Hsieh SD,Tsuji H,Saito K,Hara S,Sone H

    更新日期:2015-04-01 00:00:00

  • The epidemiology of elevated blood pressure as an estimate for hypertension in Aydin, Turkey.

    abstract:BACKGROUND:Hypertension is an important public health problem, with some variability of its epidemiological properties in different populations. OBJECTIVES:The purpose of this study was to estimate the prevalence of hypertension and to determine the hypertension awareness, treatment and control rates in Aydin, a Turki...

    journal_title:Journal of human hypertension

    pub_type: 杂志文章

    doi:10.1038/sj.jhh.1000824

    authors: Sönmez HM,Başak O,Camci C,Baltaci R,Karazeybek HS,Yazgan F,Ertin I,Celik SC

    更新日期:1999-06-01 00:00:00

  • Arterial waveform parameters in a large, population-based sample of adults: relationships with ethnicity and lifestyle factors.

    abstract::Little is known about how aortic waveform parameters vary with ethnicity and lifestyle factors. We investigated these issues in a large, population-based sample. We carried out a cross-sectional analysis of 4798 men and women, aged 50-84 years from Auckland, New Zealand. Participants were 3961 European, 321 Pacific, 2...

    journal_title:Journal of human hypertension

    pub_type: 杂志文章

    doi:10.1038/jhh.2016.78

    authors: Sluyter JD,Hughes AD,Thom SA,Lowe A,Camargo CA Jr,Hametner B,Wassertheurer S,Parker KH,Scragg RK

    更新日期:2017-05-01 00:00:00

  • Clinical relevance of visit-to-visit blood pressure variability: impact on renal outcomes.

    abstract::An impaired renal function has been found associated with very high cardiovascular (CV) risk, especially in subjects with type 2 diabetes. Microalbuminuria is a sensitive early marker of renal damage, often preceding the more advanced stages of diabetic nephropathy. Consistent evidence has been provided that any degre...

    journal_title:Journal of human hypertension

    pub_type: 杂志文章,评审

    doi:10.1038/jhh.2013.96

    authors: Parati G,Liu X,Ochoa JE

    更新日期:2014-07-01 00:00:00

  • Left ventricular hypertrophy, blood pressure and ACE genotype in untreated hypertension.

    abstract::It has been suggested that the deletion polymorphism of the angiotensin-converting enzyme (ACE) genotype may be important in the development of left ventricular hypertrophy (LVH). In order to test this hypothesis we investigated the interaction between blood pressure (BP), LVH and ACE genotype in 86 previously untreat...

    journal_title:Journal of human hypertension

    pub_type: 杂志文章

    doi:10.1038/sj.jhh.1000491

    authors: Mayet J,O'Kane KP,Elton R,Johnstone HA,Shahi M,Ozkor MA,Stanton AV,Poulter NR,Sever PS,Foale RA,Webb DJ,Thom SA

    更新日期:1997-09-01 00:00:00

  • Effects of heart rate variability biofeedback on cardiovascular responses and autonomic sympathovagal modulation following stressor tasks in prehypertensives.

    abstract::Autonomic dysfunction is implicated in prehypertension, and previous studies have suggested that therapies that improve modulation of sympathovagal balance, such as biofeedback and slow abdominal breathing, are effective in patients with prehypertension at rest. However, considering that psychophysiological stressors ...

    journal_title:Journal of human hypertension

    pub_type: 杂志文章

    doi:10.1038/jhh.2015.27

    authors: Chen S,Sun P,Wang S,Lin G,Wang T

    更新日期:2016-02-01 00:00:00

  • Elevated microRNA-34a contributes to trophoblast cell apoptosis in preeclampsia by targeting BCL-2.

    abstract::Preeclampsia (PE) is one of the most common pregnancy-specific pathologic complications, and is characterised by onset of hypertension and proteinuria. Placental trophoblast cell apoptosis is generally accepted as a major cause of PE. However, the details of the mechanism underlying the condition remain unclear. Here,...

    journal_title:Journal of human hypertension

    pub_type: 杂志文章

    doi:10.1038/jhh.2017.65

    authors: Guo M,Zhao X,Yuan X,Li P

    更新日期:2017-12-01 00:00:00

  • Particle numbers of lipoprotein subclasses and arterial stiffness among middle-aged men from the ERA JUMP study.

    abstract::We examined the association between serum lipoprotein subclasses and the three measures of arterial stiffness, that is, (i) carotid-femoral pulse wave velocity (cfPWV), which is a gold standard measure of central arterial stiffness, (ii) brachial-ankle PWV (baPWV), which is emerging as a combined measure of central an...

    journal_title:Journal of human hypertension

    pub_type: 杂志文章,多中心研究

    doi:10.1038/jhh.2013.60

    authors: Vishnu A,Choo J,Masaki KH,Mackey RH,Barinas-Mitchell E,Shin C,Willcox BJ,El-Saed A,Seto TB,Fujiyoshi A,Miura K,Lee S,Sutton-Tyrrell K,Kuller LH,Ueshima H,Sekikawa A,ERA JUMP Study Group.

    更新日期:2014-02-01 00:00:00

  • Positive association of CYP11B2 gene polymorphism with genetic predisposition to essential hypertension.

    abstract::Predispositions to essential hypertension and cardiovascular diseases are possibly associated with gene polymorphisms of the renin-angiotensin system. Gene polymorphisms of angiotensinogen and angiotensin-converting enzyme genes have been suggested to be risk factors for hypertension and myocardial infarction. Concern...

    journal_title:Journal of human hypertension

    pub_type: 杂志文章

    doi:10.1038/sj.jhh.1001484

    authors: Tsukada K,Ishimitsu T,Teranishi M,Saitoh M,Yoshii M,Inada H,Ohta S,Akashi M,Minami J,Ono H,Ohrui M,Matsuoka H

    更新日期:2002-11-01 00:00:00

  • Interrelationship between aortic stiffness and proteinuria in chronic kidney disease.

    abstract::Aortic stiffness and proteinuria are cardiovascular risk factors that are generally associated with each other. We analysed whether this is true for patients with chronic kidney disease (CKD). We hypothesized that in CKD patients of young age and predominant sole renal disease, aortic stiffness has no predictive value...

    journal_title:Journal of human hypertension

    pub_type: 杂志文章

    doi:10.1038/jhh.2009.108

    authors: Pan CR,Roos M,Schmaderer C,Lutz J,Wang JG,Heemann U,Baumann M

    更新日期:2010-09-01 00:00:00

  • Acute exercise-induced nitric oxide production contributes to upregulation of circulating endothelial progenitor cells in healthy subjects.

    abstract::Exercise has been proved to promote the number and activity of circulating endothelial progenitor cells (EPCs) in humans, which contributes to improvement in endothelial function and maintenance of cardiovascular homoeostasis. However, the mechanism underlying the effect of exercise on circulating EPCs in healthy subj...

    journal_title:Journal of human hypertension

    pub_type: 杂志文章

    doi:10.1038/sj.jhh.1002171

    authors: Yang Z,Wang JM,Chen L,Luo CF,Tang AL,Tao J

    更新日期:2007-06-01 00:00:00

  • Prevalence, awareness, treatment and control of hypertension in the elderly: results from a population survey.

    abstract::Prevalence, awareness, treatment and control of hypertension were assessed in 1032 (90%) of 1147 elderly (> or = 65 years) inhabitants of three Italian villages. Blood pressure (BP) was measured at home on two separate occasions following a standardised protocol. Persons taking antihypertensive drugs or with BP values...

    journal_title:Journal of human hypertension

    pub_type: 杂志文章

    doi:10.1038/sj.jhh.1001117

    authors: Prencipe M,Casini AR,Santini M,Ferretti C,Scaldaferri N,Culasso F

    更新日期:2000-12-01 00:00:00

  • Increased pulse pressure and carotid vascular resistance in normotensive black African subjects.

    abstract::To evaluate ethnic differences in cerebral circulation, an index of carotid vascular resistance (RI) was determined by continuous wave Doppler ultrasound. Validation of the index resulted from a significant correlation between RI and carotid vascular resistance obtained from direct measurement of blood pressure and ca...

    journal_title:Journal of human hypertension

    pub_type: 杂志文章

    doi:

    authors: Toto-Moukouo JA,Safar ME

    更新日期:1990-06-01 00:00:00

  • Preeclampsia: effect on newborn blood pressure in the 3 days following preterm birth: a cohort study.

    abstract::Maternal hypertension and preeclampsia are associated with greater risk of hypertension in childhood, and cardiovascular events in adulthood. However, whether preeclampsia affects blood pressure (BP) in the newborn period is unclear. Previous neonatal studies were based on small sample sizes, very low birth weight or ...

    journal_title:Journal of human hypertension

    pub_type: 杂志文章

    doi:10.1038/jhh.2014.50

    authors: Reveret M,Boivin A,Guigonnis V,Audibert F,Nuyt AM

    更新日期:2015-02-01 00:00:00

  • Urinary calcium excretion, sodium intake and blood pressure in a multi-ethnic population: results of the Wandsworth Heart and Stroke Study.

    abstract:BACKGROUND:Hypertension is associated with increased urinary calcium excretion (UCa). A high sodium intake increases both UCa and blood pressure (BP). However, it is not clear whether these effects are modified by gender or ethnic origin. OBJECTIVES:To examine the relationships between BP, urinary sodium (UNa), gender...

    journal_title:Journal of human hypertension

    pub_type: 杂志文章

    doi:10.1038/sj.jhh.1001171

    authors: Blackwood AM,Sagnella GA,Cook DG,Cappuccio FP

    更新日期:2001-04-01 00:00:00

  • Left ventricular mass is related to endothelium-dependent vasodilation in the forearm, but not in the brachial artery, in elderly subjects: the Prospective Investigation of the Vasculature in Uppsala Seniors study.

    abstract::Left ventricular hypertrophy (LVH) is a powerful cardiovascular risk factor and has previously been related to endothelium-dependent vasodilation (EDV) in hypertensive patients. In the Prospective Investigation of the Vasculature in Uppsala Seniors study, different techniques to evaluate EDV in different types of vess...

    journal_title:Journal of human hypertension

    pub_type: 杂志文章

    doi:10.1038/jhh.2008.61

    authors: Lind L

    更新日期:2008-11-01 00:00:00

  • Prevalence of poor sleep quality and its associated factors among hypertensive patients on follow up at Jimma University Medical Center.

    abstract::Several studies have reported an association between the abnormal duration of sleep and chronic conditions including hypertension. However, the existing body of evidence is not entirely significant; as insignificant associations between poor sleep and blood pressure (BP) have been found across different studies. The a...

    journal_title:Journal of human hypertension

    pub_type: 杂志文章

    doi:10.1038/s41371-020-0320-x

    authors: Birhanu TE,Getachew B,Gerbi A,Dereje D

    更新日期:2021-01-01 00:00:00

  • Soluble vascular endothelial growth factor receptor-1 is reduced in patients with resistant hypertension after renal denervation.

    abstract::Renal denervation (RDN) has been shown in several studies to reduce blood pressure (BP) in patients with resistant hypertension (RH). Data on potential biomarkers associated with BP changes remain scarce. We evaluated whether soluble vascular endothelial growth factor receptor (sVEGFR-1) is affected by the procedure. ...

    journal_title:Journal of human hypertension

    pub_type: 杂志文章

    doi:10.1038/jhh.2016.64

    authors: Eikelis N,Hering D,Marusic P,Walton AS,Lambert EA,Sata Y,Krum H,Lambert GW,Esler MD,Schlaich MP

    更新日期:2017-04-01 00:00:00

  • A physician-pharmacist model for the surveillance of blood pressure in the community: a feasibility study.

    abstract::Hypertension is poorly managed. Hospital-based pharmacists working with physicians have been shown to improve the rate of achievement of "target" blood pressure in selected patients. It is unknown if such schemes can operate in the community and to what extent they would attract volunteers with poorly managed blood pr...

    journal_title:Journal of human hypertension

    pub_type: 杂志文章

    doi:10.1038/sj.jhh.1001220

    authors: Earle KA,Taylor P,Wyatt S,Burnett S,Ray J

    更新日期:2001-08-01 00:00:00

  • Effect of antihypertensive treatment on qualitative estimates of microalbuminuria.

    abstract::We tested the utility of qualitative microalbuminuria (MAU) screening in an office practice setting, in assessing the response of MAU to drug treatment. We enrolled general practitioners throughout Germany, who obtained histories, physical examinations, and routine laboratory values as clinically indicated on > 6000 n...

    journal_title:Journal of human hypertension

    pub_type: 杂志文章

    doi:

    authors: Agrawal B,Wolf K,Berger A,Luft FC

    更新日期:1996-08-01 00:00:00

  • Arterial compliance may be reduced by ingestion of red wine.

    abstract::The aim of this study was to assess the effect of alcohol on blood pressure and arterial compliance over 24 h in a group of volunteers, comparing the same group of subjects on two consecutive but separate days, one with alcohol intake (alcohol day) and one free of alcohol (control day). We studied 18 healthy subjects ...

    journal_title:Journal of human hypertension

    pub_type: 杂志文章,随机对照试验

    doi:10.1038/jhh.2015.19

    authors: Fantin F,Bulpitt CJ,Zamboni M,Cheek E,Rajkumar C

    更新日期:2016-01-01 00:00:00

  • Role of the Gly460Trp polymorphism of the alpha-adducin gene in primary hypertension in Scandinavians.

    abstract::Previous studies have suggested that the Trp460 allele of the Gly460Trp polymorphism in the alpha-adducin gene is associated with salt sensitivity and primary hypertension. The present study was undertaken to evaluate if the Trp460 allele of this polymorphism is associated with primary hypertension in Scandinavians. T...

    journal_title:Journal of human hypertension

    pub_type: 杂志文章

    doi:10.1038/sj.jhh.1000942

    authors: Melander O,Bengtsson K,Orho-Melander M,Lindblad U,Forsblom C,Råstam L,Groop L,Hulthén UL

    更新日期:2000-01-01 00:00:00

  • Comparison of cilazapril and nifedipine retard on ambulatory blood pressure, metabolic, rheological and platelet function in hypertensive patients.

    abstract::In a 12 week randomised, double-blind study, a total of 31 patients with a sitting DBP of between 95 and 115 mmHg were enrolled for comparison of the antihypertensive, metabolic and antiplatelet effects of the drugs cilazapril and nifedipine retard. A two week placebo treatment was given before either cilazapril (2.5 ...

    journal_title:Journal of human hypertension

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Ding YA,Law HW,Chou TC

    更新日期:1994-02-01 00:00:00