Three female familial cases of solid pseudopapillary tumors with a protease serine 1 gene mutation.

abstract：OBJECTIVE:Green tea polyphenols have been shown to inhibit tumor growth in animal and in vitro studies. We examined the relationship between green tea consumption and the risk of death from pancreatic cancer in a large Japanese cohort. METHODS:At baseline (1988-1990), study participants reported the frequency and amou...

journal_title：Pancreas

authors： Lin Y,Kikuchi S,Tamakoshi A,Yagyu K,Obata Y,Kurosawa M,Inaba Y,Kawamura T,Motohashi Y,Ishibashi T,JACC Study Group.

更新日期：2008-07-01 00:00:00

abstract：:We report a case of severe acute pancreatitis associated with both gastric and abdominal wall infarction. The early skin changes on the anterior abdominal wall could be confused with Grey-Turner's sign. ...

journal_title：Pancreas

authors： Scholefield JH,Goodman AJ,Morgan WP

更新日期：1988-01-01 00:00:00

abstract：OBJECTIVES:Clinical trials are a prerequisite for evidence-based medicine. Trial representativity by internal and external validities is an assumption for a transfer into the real world. METHODS:A questionnaire addressing several forms of bias was established. Randomized controlled trials for adjuvant treatment of pan...

journal_title：Pancreas

authors： Sorg C,Schmidt J,Büchler MW,Edler L,Märten A

更新日期：2009-07-01 00:00:00

abstract：OBJECTIVES:The median age of patients with pancreatic ductal adenocarcinoma (PDAC) is approximately 70 years, and PDAC rarely affects individuals younger than 40 years. Here, we investigated clinicopathologic features and genetic background of PDAC occurring in young patients (age ≤ 40 years) to determine whether any d...

journal_title：Pancreas

authors： Ohmoto A,Yachida S,Kubo E,Takai E,Suzuki M,Shimada K,Okusaka T,Morizane C

更新日期：2016-08-01 00:00:00

abstract：:To investigate the heterogeneity of hematogenous metastases of pancreatic ductal carcinoma, we investigated carcinomatous spread in 130 autopsy cases. Hepatic metastases occurred most frequently, in 81 cases (62%), which may be explained by the fact that all veins draining the pancreas flow into the portal system. We ...

journal_title：Pancreas

authors： Kamisawa T,Isawa T,Koike M,Tsuruta K,Okamoto A

更新日期：1995-11-01 00:00:00

abstract：:Amyloid was isolated from islets of amyloidotic pancreata of monkey and human beings by solubilization of non-amyloid materials from the pancreas and digestion of contaminating collagen and elastin. The resulting pellet was estimated to be greater than 90% pure islet amyloid. Antibodies specific for monkey islet amylo...

journal_title：Pancreas

authors： Fang TY,Howard CF Jr

更新日期：1986-01-01 00:00:00

abstract：:Hepatocyte growth factor (HGF) is a widely expressed growth factor secreted by cells of mesenchymal origin, which has been shown to be involved in growth processes of multiple cell types. The HGF receptor, the product of the c-met protooncogene, is expressed mainly by epithelial cells. Increased expression of the HGF ...

journal_title：Pancreas

authors： Kiehne K,Herzig KH,Fölsch UR

更新日期：1997-07-01 00:00:00

abstract：:Neuroendocrine tumors (NETs) arise in most organs of the body and share many common pathologic features. However, a variety of different organ-specific systems have been developed for nomenclature, grading, and staging of NETs, causing much confusion. This review examines issues in the pathologic assessment of NETs th...

journal_title：Pancreas

authors： Klimstra DS,Modlin IR,Coppola D,Lloyd RV,Suster S

更新日期：2010-08-01 00:00:00

abstract：OBJECTIVES:The aims of this study were to evaluate diagnostic value of endoscopic ultrasound strain ratio elastography in patients with focal pancreatic masses and to determine the cutoff value between the pancreatic malignancies and inflammatory pancreatic masses using reference areas different than those used by othe...

journal_title：Pancreas

authors： Rustemović N,Kalauz M,Grubelić Ravić K,Iveković H,Bilić B,Ostojić Z,Opačić D,Ledinsky I,Majerović M,Višnjić A

更新日期：2017-03-01 00:00:00

abstract：:Adenosine-5'-O-(2-thiodiphosphate) (ADP beta S), a P2y purinergic agonist, has been shown to be a potent insulin secretagogue on the isolated rat pancreas. In the present work the effects of ADP beta S on insulin somatostatin, and glucagon secretions were investigated in dogs. In vivo, in anesthetized fasted dogs, i.v...

journal_title：Pancreas

authors： Hillaire-Buys D,Gross R,Parés-Herbuté N,Ribes G,Loubatières-Mariani MM

更新日期：1994-09-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to assess the relationship between the computed tomography (CT) pancreatic parenchyma attenuation value and clinically relevant postoperative pancreatic fistula (POPF). METHODS:The medical records of 115 patients who underwent pancreaticoduodenectomy and preoperative dynamic CT were...

journal_title：Pancreas

authors： Maehira H,Iida H,Mori H,Kitamura N,Miyake T,Shimizu T,Tani M

更新日期：2019-02-01 00:00:00

abstract：:Chemoprevention by a synthetic retinoid, selenium, and these agents in combination during the postinitiation stages of carcinogenesis induced in rats by azaserine was evaluated. Male Lewis rats were given three weekly injections of 30 mg/kg azaserine while being fed a purified diet. One week after completion of carcin...

journal_title：Pancreas

authors： Curphey TJ,Kuhlmann ET,Roebuck BD,Longnecker DS

更新日期：1988-01-01 00:00:00

abstract：OBJECTIVES:Activation of "nicotinic anti-inflammatory pathway" could reduce severity of inflammation and injury induced by acute pancreatitis. However, the role of regulatory T (Treg) cells in this pathway is unclear. METHODS:Severe acute pancreatitis (SAP) was induced in mice through retrograde injection of 50-μL 2% ...

journal_title：Pancreas

authors： Zheng YS,Wu ZS,Zhang LY,Ke L,Li WQ,Li N,Li JS

更新日期：2015-04-01 00:00:00

abstract：OBJECTIVES:To evaluate the systemic effects of moderate hypothermia (MH) and the timing of induction on acute pancreatitis (AP) and endotoxemia in rats. METHODS:The effects of MH were compared in 4 groups, that is, sham group (38 degrees C), control group (38 degrees C), early MH group (32 degrees C on administration ...

journal_title：Pancreas

authors： Fujimoto K,Fujita M,Tsuruta R,Tanaka R,Shinagawa H,Izumi T,Kasaoka S,Maekawa T

更新日期：2008-08-01 00:00:00

abstract：:The effects of manganese (Mn2+) on phosphorylation activity in the rat pancreas were examined in an in vitro phosphorylation assay and by sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) of endogenous proteins. Several histones were phosphorylated in the presence of pancreatic supernatant obtained ...

journal_title：Pancreas

authors： Brockenbrough JS,Korc M

更新日期：1990-09-01 00:00:00

abstract：OBJECTIVES:The 2012 international consensus guidelines for the management of intraductal papillary mucinous neoplasm (IPMN) of the pancreas stratified patients into 2 clinical categories, "high-risk stigmata" and "worrisome features," and recommended different therapeutic strategies for these groups. The aim of this st...

journal_title：Pancreas

authors： Aso T,Ohtsuka T,Matsunaga T,Kimura H,Watanabe Y,Tamura K,Ideno N,Osoegawa T,Takahata S,Shindo K,Ushijima Y,Aishima S,Oda Y,Ito T,Mizumoto K,Tanaka M

更新日期：2014-11-01 00:00:00

abstract：OBJECTIVES:Our aim was to establish and characterize a novel pancreatic ductal adenocarcinoma cell line from a patient in whom the origin of the invasive carcinoma could be traced back to the intraductal papillary mucinous neoplasm (IPMN) precursor lesion. METHODS:The primary patient-derived tumor was propagated in im...

journal_title：Pancreas

authors： Heller A,Angelova AL,Bauer S,Grekova SP,Aprahamian M,Rommelaere J,Volkmar M,Janssen JW,Bauer N,Herr I,Giese T,Gaida MM,Bergmann F,Hackert T,Fritz S,Giese NA

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVES:Patients with chronic pancreatitis are managed by extracorporeal shock wave lithotripsy (ESWL) for pancreatic stones. Stone density on noncontrast computed tomography (NCCT) is used to predict stone composition and fragility, but no report investigating the pancreatic stone density has been documented. We ai...

journal_title：Pancreas

authors： Ohyama H,Mikata R,Ishihara T,Tsuyuguchi T,Sakai Y,Sugiyama H,Yasui S,Ishii K,Itoh S,Nishikawa T,Watanabe Y,Yokosuka O

更新日期：2015-04-01 00:00:00

abstract：:Free radicals have been implicated in beta-cell destruction. pancreatic antioxidant enzymatic defenses provide significant endogenous protection from these highly cytotoxic effector molecules. In our colony of BB rats, the reliability of peripheral blood lymphocyte count (PBLC) as a predictor of diabetes onset was ass...

journal_title：Pancreas

authors： Roza AM,Pieper GM,Johnson CP,Adams MB

更新日期：1995-01-01 00:00:00

abstract：OBJECTIVES:To correlate magnetic resonance cholangiopancreatography (MRCP) and magnetic resonance imaging (MRI) findings of the pancreas with the pancreatic exocrine function determined by fecal elastase 1 concentration. METHODS:Magnetic resonance imaging and MRCP findings of 81 consecutive patients with clinically su...

journal_title：Pancreas

authors： Bilgin M,Bilgin S,Balci NC,Momtahen AJ,Bilgin Y,Klör HU,Rau WS

更新日期：2008-01-01 00:00:00

abstract：:A case of papillary cystic tumor (PCT) of the pancreas in a 55-year-old woman is described. She presented with a gradually enlarging and painless abdominal mass for > 26 years. The tumor was encapsulated and measured 16 x 12 x 10 cm. The gross features and conventional light microscopic appearance of this tumor were c...

journal_title：Pancreas

authors： Lee WY,Tzeng CC,Jin YT,Chow NH,Yip CM,Lee JC

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVES:To measure the usefulness of Ki-67 proliferative index (Ki-67 index) as a prognostic variable for grading pancreatic neuroendocrine tumors. METHODS:A multi-institutional prospective database comprising 350 patients. Grading based on mitotic activity (<2 mitoses/10 high-power fields, 2-20 and >20) and Ki-67 ...

journal_title：Pancreas

authors： Philips P,Kooby DA,Maithel S,Merchant NB,Weber SM,Winslow ER,Ahmad S,Kim HJ,Scoggins CR,McMasters KM,Martin RCG 2nd

更新日期：2018-03-01 00:00:00

abstract：:Peptide YY (PYY) is a recently isolated gut peptide that is found primarily in the mucosal endocrine cells of the terminal ileum, colon, and rectum of several mammalian species, including humans. The purpose of this study was to characterize the effect of PYY on pancreatic exocrine secretion in six conscious dogs prep...

journal_title：Pancreas

authors： Lluis F,Gomez G,Fujimura M,Greeley GH Jr,Thompson JC

更新日期：1987-01-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to investigate the biochemical and functional properties of a rat acellular pancreatic bioscaffolds (APBs). METHODS:Fresh pancreata from 10 rats were soaked and perfused through portal veins using Easy-Load Digital Drive peristaltic pumps. The histological structure, extracellular ma...

journal_title：Pancreas

authors： Wang X,Li YG,Du Y,Zhu JY,Li Z

更新日期：2018-09-01 00:00:00

abstract：:Lipid peroxidation, which may be involved in the pathogenesis of acute pancreatitis, is usually assessed in vitro or indirectly using antioxidants or free radical scavengers. We assessed lipid peroxidation in an in vivo model by measuring ethane exhalation in two models of acute pancreatitis. Edematous acute pancreati...

journal_title：Pancreas

authors： Lévy P,Lettéron P,Paye F,Molas G,Guimont MC,Pessayre D,Bernades P,Rozé C

更新日期：1997-05-01 00:00:00

abstract：:It has recently been shown that the infusion of oleic acid into the rat pancreaticobiliary duct causes a reproducible and long-lasting atrophy of the exocrine pancreas. The effects of this pancreatic atrophy on non-invasive pancreatic function tests have not been fully characterized. This study was undertaken to deter...

journal_title：Pancreas

authors： Henry JP,Steinberg WM

更新日期：1993-09-01 00:00:00

abstract：OBJECTIVES:This analysis investigated nomogram use to evaluate metastatic pancreatic cancer prognosis. METHODS:Thirty-four baseline factors were examined in the Metastatic Pancreatic Adenocarcinoma Clinical Trial (MPACT) (nab-paclitaxel plus gemcitabine vs gemcitabine) data set. Factors significantly (P < 0.1) associa...

journal_title：Pancreas

authors： Goldstein D,Von Hoff DD,Chiorean EG,Reni M,Tabernero J,Ramanathan RK,Botteman M,Aly A,Margunato-Debay S,Lu B,Louis CU,McGovern D,Lee CK

更新日期：2020-07-01 00:00:00

abstract：:With a nitrosamine induced hamster pancreatic cancer cell line (HaP-T1), survival time and metastatic rates were compared between orthotopic cell implantation (OCI; n = 5) and orthotopic tissue implantation (OTI; n = 5) models. All the tumors were palpable (100% tumor take) after 1 week in both groups. Hamsters in the...

journal_title：Pancreas

authors： Morioka CY,Saito S,Ohzawa K,Watanabe A

更新日期：2000-03-01 00:00:00

abstract：OBJECTIVES:Cigarette smoking is an independent risk factor for chronic pancreatitis. We conducted a systematic review of the literature assessing whether cigarette smoking is a risk factor for acute pancreatitis (AP) and recurrent AP (RAP). METHODS:MEDLINE, PubMed, Embase, and Cochrane Database of Systematic Reviews w...

journal_title：Pancreas

authors： Majumder S,Gierisch JM,Bastian LA

更新日期：2015-05-01 00:00:00

abstract：OBJECTIVES:Prior studies have indicated that endogenous or exogenous cholecystokinin (CCK) induces transient acinar cell proliferation at about 24 hours after its stimulation. The aims of the present study were to determine the time point when the administration of the CCK-A-receptor antagonist loxiglumide had its maxi...

journal_title：Pancreas

authors： Kanemitsu D,Sakagami J,Motoyoshi T,Nakajima T,Kataoka K

更新日期：2006-03-01 00:00:00