Abstract:
:Organic acids and bases are among the most frequently used chemicals in the manufacturing industries. However, the toxicology of only a number of them has been fully characterized, and for fewer still have occupational exposure limits been established. This paper reviews the acute and chronic toxicity data of the organic acids and bases, and considers the mechanism by which these chemicals produce their effects. A methodology for establishing preliminary occupational exposure limits based on the physicochemical properties of these chemicals is presented. Workplace exposure limits for 20 organic acids and bases which currently have no exposure guidelines are suggested. Advice regarding appropriate medical treatment of exposure to these materials is discussed.
journal_name
Am J Ind Medjournal_title
American journal of industrial medicineauthors
Leung HW,Paustenbach DJdoi
10.1002/ajim.4700180610subject
Has Abstractpub_date
1990-01-01 00:00:00pages
717-35issue
6eissn
0271-3586issn
1097-0274journal_volume
18pub_type
杂志文章,评审abstract:BACKGROUND:Studies comparing different forms of asbestos are rare, and limited by the failure to compare results with unexposed populations. We compare autoimmune responses among former workers and residents of the crocidolite mining and milling town of Wittenoom, Western Australia, with an unexposed population. METHO...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22863
更新日期:2018-07-01 00:00:00
abstract::Several recent studies (animal and human) have suggested an association between lung cancer and silica exposure. To test the hypothesis, we have studied death benefit records of 1,905 members of the Granite Cutters Union. A proportionate mortality analysis (PMR) was conducted, using U.S. deaths as a comparison populat...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700090210
更新日期:1986-01-01 00:00:00
abstract:BACKGROUND:Despite the human and monetary costs of occupational injury and illness, occupational health care has focused more on treatment than prevention, and prevention is not part of many clinical occupational health practices. This represents a failure of occupational health care to meet the health care needs of th...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.1105
更新日期:2001-09-01 00:00:00
abstract:BACKGROUND:Many newly constructed green buildings (GB) are certified using the United States Green Building Council (USGBC) Leadership in Energy and Environmental Design (LEED) rating system for new construction and major renovation which focuses on architectural and mechanical design to conserve energy, reduce environ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22166
更新日期:2013-04-01 00:00:00
abstract::The authors developed a union sponsored 2-day human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) "train the trainer" program for healthcare workers in the San Francisco Bay Area. The program incorporated the "education for action" approach in an effort to respond to the inadequacies in many tra...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700220509
更新日期:1992-01-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to examine the association between Dupuytren's contracture (DC), repetitive handwork (RHW), heavy handwork (HHW), and/or vibration exposure. METHODS:Frequency and intensity of the three types of handwork were collected and compared between DC patients and controls. Hours of wo...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22736
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:Acoustic neuroma is the intracranial tumor subtype showing the highest relative risk in relation to ionizing radiation but other environmental risk factors are largely unknown. This study was performed to investigate the effect of power frequency magnetic fields. METHOD:A total of 793 cases between 1987 and...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20251
更新日期:2006-02-01 00:00:00
abstract:BACKGROUND:Neck pain is a prevalent musculoskeletal condition among workers in the United States. This study explores a set of workplace psychosocial and organization-related factors for neck pain. METHODS:Data used for this study come from the 2010 National Health Interview Survey which provides a representative samp...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22602
更新日期:2016-07-01 00:00:00
abstract:BACKGROUND:Asbestos fibers are known to accumulate in lung parenchyma and thoracic lymph nodes, but their presence and translocation into the extrapulmonary tissues need clarification. We assessed the presence of asbestos in the para-aortic (PA) and mesenteric (ME) lymph nodes. METHODS:PA and ME lymph nodes and lung t...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20694
更新日期:2009-06-01 00:00:00
abstract::In 1979, a pilot survey defined respiratory status and unmet health care needs of retired and former male asbestos workers in Hawaii. Of 1,401 identified subjects, 741 were contacted and 411 were interviewed. Forty-five subjects were between 39 and 54 years of age; 208, between 55 and 64; and 158, age 65 or more. They...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700060208
更新日期:1984-01-01 00:00:00
abstract::The objective of this study was to examine the endocrine profiles of a group of male workers chronically exposed to trichloroethylene (TCE) in an electronics factory. A total of 124 workers participated in a preliminary study, for which 85 satisfied the selection criteria and were recruited to take part in a more deta...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(sici)1097-0274(199709)32:3<217::aid-ajim6
更新日期:1997-09-01 00:00:00
abstract:BACKGROUND:Thoroughbred horse farm workers self-report a high frequency of work-related injuries and pain. However, an analysis of Thoroughbred horse farm workers' compensation injury claims is absent from the literature, yet may benefit worker safety. METHODS:We analyzed workers' compensation insurance firm data cont...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.23159
更新日期:2020-10-01 00:00:00
abstract:BACKGROUND:Biomass cooking fuel is the main source of indoor air pollution in the majority of households in the developing world. Sri Lanka is an island of about 20 million population with urban, rural, and estate population of 14.6%, 80.0%, and 5.4%, respectively. This study describes biomass fuel use for cooking in S...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.21023
更新日期:2012-12-01 00:00:00
abstract::Cohort mortality and nested case-control studies were conducted involving 2,901 men employed 1 year or more between 1940 and 1986 at any of four California facilities of a major chemical company. Employees experienced fewer deaths from each of the major causes than were expected based on U.S., California, and local co...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700220107
更新日期:1992-01-01 00:00:00
abstract:BACKGROUND:In this study, we describe the methodology used for historical estimation of exposure to fluoride and to PAH in vertical stud Søderberg (VSS) potrooms at two Norwegian aluminum smelters. The assessment was performed in order to develop exposure data for epidemiological studies of cause-specific mortality and...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(sici)1097-0274(199902)35:2<164::aid-ajim8
更新日期:1999-02-01 00:00:00
abstract:BACKGROUND:Hispanic immigrant workers dominate California's hired farm workforce. Little is known about their health status; even less is known about those lacking employment authorization. METHODS:The California Agricultural Workers Health Survey (CAWHS) was a statewide cross-sectional household survey conducted in 1...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20796
更新日期:2010-04-01 00:00:00
abstract:BACKGROUND:The Oak Ridge, Tennessee Y-12 plant has operated as a nuclear materials fabrication plant since the 1940s. Given the work environment, and prior findings that lung cancer mortality was elevated among white male Y-12 workers relative to US white males, we investigated whether lung cancer mortality was associa...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20254
更新日期:2006-02-01 00:00:00
abstract::Two workers (23 and 28 years old) developed rhinitis and bronchial asthma after occupational contact with the isocyanate MDI. Positive skin prick test results for MDI-HSA and IgE antibodies to all isocyanate-HSA conjugates were obtained in both cases, and the inhalation challenge test with MDI produced immediate and l...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(SICI)1097-0274(199605)29:5<467::AID-AJIM5
更新日期:1996-05-01 00:00:00
abstract::The National Research Council's report "Protecting Youth at Work" addresses the health and safety consequences of work by youth in the United States. The report finds that a higher proportion of U.S. youth work than in any other developed nation and that as much as 80% of youth will have worked during their high schoo...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(sici)1097-0274(199911)36:5<579::aid-ajim1
更新日期:1999-11-01 00:00:00
abstract::Attitudes of occupational health care professionals toward smoking and their activity to address smoking issues were investigated by a questionnaire survey. Data were also collected on employees' exposure to environmental tobacco smoke and on smoking policies that existed in workplaces. Questionnaires were mailed to a...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(sici)1097-0274(199807)34:1<73::aid-ajim10
更新日期:1998-07-01 00:00:00
abstract::The occupational injury experience of the U.S. and Australian construction industries for 1988-1991 was compared to identify similarities and differences in risk and to share information vital for planning strategies for prevention. There were 4,158 deaths in the U.S. and 264 in the Australian construction industries....
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(SICI)1097-0274(199608)30:2<202::AID-AJIM1
更新日期:1996-08-01 00:00:00
abstract:BACKGROUND:Hotel room cleaners have physically demanding jobs that place them at high risk for shoulder pain. Psychosocial work factors may also play a role in shoulder pain, but their independent role has not been studied in this group. METHODS:Seventy-four percent (941 of 1,276) of hotel room cleaners from five Las ...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.20832
更新日期:2010-07-01 00:00:00
abstract::Measurement of specific organic compounds in exhaled breath has been used as an indicator of recent exposure to pollutants or as an indicator of the health of an individual. A typical application involves the collection of multiple breaths onto a sorbent cartridge or into an evacuated canister with the use of a relati...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700280110
更新日期:1995-07-01 00:00:00
abstract:BACKGROUND:The prerequisites necessary for attributing lung carcinoma to asbestos, represent a controversial issue. METHODS:Three parameters (occupational history, pleural plaques, and lung asbestos bodies) were investigated in 414 consecutive cases of lung carcinoma, examined at necropsy at the Hospital of Monfalcone...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/(sici)1097-0274(199909)36:3<360::aid-ajim3
更新日期:1999-09-01 00:00:00
abstract::The aim of the investigation was to study whether laboratory work or other types of chemical work at one petrochemical plant were associated with an increased risk for miscarriage or reduced birthweight. The study was based on questionnaire data for 95% of the women working at the plant between 1973 and 1987. A statis...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700160507
更新日期:1989-01-01 00:00:00
abstract::Mitoplasts from rabbit bone marrow cells in vitro incubated with benzene metabolites showed a concentration-dependent inhibition of mitochondrial RNA synthesis. The 50% molar inhibitory concentration for each metabolite was determined to be p-benzoquinone, 2 X 10(-6); phenol, 2.5 X 10(-5); hydroquinone, 5 X 10(-5); ca...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700070512
更新日期:1985-01-01 00:00:00
abstract::Thirty-eight patients with a diagnosis of malignant mesothelioma participated in a semi-structured interview to evaluate asbestos exposure, acquisition of increased risk information, and retrospective reporting of cognitive and behavioral reactions (particularly smoking behavior) to risk information. Twenty-eight pati...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.4700040306
更新日期:1983-01-01 00:00:00
abstract:BACKGROUND:Deaths due to occupational disease and injury place a heavy burden on society in terms of economic costs and human suffering. METHODS:We estimate the annual deaths due to selected diseases for which an occupational association is reasonably well established and quantifiable, by calculation of attributable f...
journal_title:American journal of industrial medicine
pub_type: 杂志文章,评审
doi:10.1002/ajim.10216
更新日期:2003-05-01 00:00:00
abstract:OBJECTIVE:To assess whether unionization prevents deterioration in self-reported health and depressive symptoms in late career transitions. METHODS:Data come from the Health and Retirement Study (N = 6475). The change in self-perceived health (SPH) and depressive symptoms (CESD) between wave 11 and wave 12 is explaine...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.22877
更新日期:2018-06-28 00:00:00
abstract:BACKGROUND:Case reports have identified hydrofluoric acid (HF) as causing fatal work injury, and HF has both local and systemic toxicity. Surveillance for HF-related mortality is problematic because of the lack of unique coding for this acid in hospital records and vital statistics. METHODS:We identified HF-related fa...
journal_title:American journal of industrial medicine
pub_type: 杂志文章
doi:10.1002/ajim.1090
更新日期:2001-08-01 00:00:00