Adverse effects of antioxidative vitamins.

Abstract:

:High doses of synthetic antioxidative vitamins: A, E, C and β-carotene are often used on long-term basis in numerous preventive and therapeutic medical applications. Instead of expected health effects, the use of those vitamins may however lead to cases of hypervitaminosis and even to intoxication. The article points out main principles of safety which are to be observed during supplementation with antioxidative vitamins. Toxic effects resulting from erroneous administration of high doses of those substances on organs and systems of the organism are also discussed. Attention is drawn to interactions of antioxidative vitamins with concomitantly used drugs, as well as intensification of adverse effects caused by various exogenous chemical factors. Moreover, the article presents the evaluation of supplementation with these vitamins, which was performed in large studies.

authors

Rutkowski M,Grzegorczyk K

doi

10.2478/S13382-012-0022-x

subject

Has Abstract

pub_date

2012-06-01 00:00:00

pages

105-21

issue

2

eissn

1232-1087

issn

1896-494X

journal_volume

25

pub_type

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