Abstract：
:Effects of combined exposure to m-xylene and n-butyl alcohol in the conditions of subchronic inhalation experiment in rats were examined. Rats were exposed to vapours of individual solvents at concentrations of 50 and 100 ppm and their 1:1 mixture at concentrations of 50 + 50 ppm and 100 + 100 ppm, 6 h/day, 5 days/week for 3 months. No significant changes in body weight gain, in absolute and relative organ weights and clinical biochemistry parameters were observed. The motor coordination disturbances caused by mixture of m-xylene and n-butyl alcohol at concentrations of 100 + 100 ppm were identical as those caused by n-butyl alcohol at concentration of 100 ppm. Thus, in condition of combined exposure, the toxic effect of m-xylene was not added to the effect of n-butyl alcohol. Significant increase in sensitivity to pain in animals exposed to m-xylene at both concentrations, and parallel lack of changes in the pain sensitivity in animals exposed to n-butyl alcohol and to the solvent mixtures was observed. n-Butyl alcohol provoked the increase of lipid peroxidation in hepatic microsomes without any induction of cytochrome P-450 monooxygenases, m-Xylene did not affect the activity of monooxygenase and lipid peroxidation rate in hepatic microsomes and moreover, in the case of combined exposure it abolished the effect on n-butyl alcohol. Results obtained in condition of acute and subchronic inhalation exposure interpreted jointly, indicate the less than additive toxic effect of combined exposure to m-xylene and n-butyl alcohol.
journal_name
Int J Occup Med Environ Healthauthors
Korsak Z,Wiśniewska-Knypl J,Swiercz Rsubject
Has Abstractpub_date
1994-01-01 00:00:00pages
155-66issue
2eissn
1232-1087issn
1896-494Xjournal_volume
7pub_type
杂志文章abstract：OBJECTIVES:Nurses are at elevated risk of burnout, anxiety and depressive disorders, and may then become less productive. This begs the question if a preventive intervention in the work setting might be cost-saving from a business perspective. MATERIAL AND METHODS:A cost-benefit analysis was conducted to evaluate the ...
journal_title：International journal of occupational medicine and environmental health
pub_type： 杂志文章,随机对照试验
doi：10.13075/ijomeh.1896.00465
更新日期：2015-01-01 00:00:00
abstract：:Breast cancer is responsible for considerable morbidity and the majority of female deaths in industrialized countries. In the etiology of breast cancer many endogenous and exogenous risk factors have been discussed. It is estimated that about 40% of all cancers in women are hormonally mediated. Both estrogens and andr...
journal_title：International journal of occupational medicine and environmental health
pub_type： 杂志文章,评审
doi：
更新日期：2003-01-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to verify the influence of a specific exercise program on the strength and resistance levels of lumbar flexors and extensors in warehouse workers. MATERIALS AND METHODS:The population used in this randomized controlled trial included 557 warehouse male workers from a food distributi...
journal_title：International journal of occupational medicine and environmental health
pub_type： 杂志文章,随机对照试验
doi：10.2478/s13382-012-0011-0
更新日期：2012-03-01 00:00:00
abstract：OBJECTIVES:This study intended to characterize work environment contamination by particles in 2 waste-sorting plants. MATERIAL AND METHODS:Particles were measured by portable direct-reading equipment. Besides mass concentration in different sizes, data related with the number of particles concentration were also obtai...
journal_title：International journal of occupational medicine and environmental health
pub_type： 杂志文章
doi：10.2478/s13382-014-0310-8
更新日期：2014-10-01 00:00:00
abstract：OBJECTIVES:It is commonly known that ergonomics in emergency medical services (EMS) is very important. Emergency medical services workers are exposed to different conditions and they should perform a variety of tasks. MATERIAL AND METHODS:The aim of the work has been to analyze the angular position of elbows and force...
journal_title：International journal of occupational medicine and environmental health
pub_type： 杂志文章
doi：10.13075/ijomeh.1896.01073
更新日期：2017-10-06 00:00:00
abstract：:Crystalline silica is a health hazard commonly encountered in work environment. Occupational exposure to crystalline silica dust concerns workers employed in such industries as mineral, fuel-energy, metal, chemical and construction industry. It is estimated that over 2 million workers in the European Union are exposed...
journal_title：International journal of occupational medicine and environmental health
pub_type： 杂志文章,评审
doi：10.2478/v10001-008-0010-3
更新日期：2008-01-01 00:00:00
abstract：OBJECTIVES:The aim of this study is to establish which psychosocial factors at work are related to depression among female white-collar workers in Vilnius. MATERIALS AND METHODS:The data was collected in a case-control study in 2002-2004. The cases were selected from patients treated at Vilnius mental health centers. ...
journal_title：International journal of occupational medicine and environmental health
pub_type： 杂志文章
doi：10.2478/s13382-011-0018-y
更新日期：2011-06-01 00:00:00
abstract：OBJECTIVES:The association between depressive symptoms and psycho-organisational work environment has been established in the literature. Some studies have evaluated depressive symptoms in healthcare workers, but little research has been carried out among nurse managers. The aim of the study is to evaluate the depressi...
journal_title：International journal of occupational medicine and environmental health
pub_type： 杂志文章
doi：10.2478/s13382-014-0264-x
更新日期：2014-04-01 00:00:00
abstract：OBJECTIVES:To investigate the influence of the anti-tumor necrosis factor-α infliximab (IFX) in the case of rats with silicosis. MATERIAL AND METHODS:Forty-eight Wistar rats were randomly divided into 3 groups. The study group (N = 16) - silicosis was induced by intratracheal instillation of 50 mg silica on day 1, and...
journal_title：International journal of occupational medicine and environmental health
pub_type： 杂志文章
doi：10.13075/ijomeh.1896.01037
更新日期：2018-07-04 00:00:00
abstract：BACKGROUND:Benzalkonium chloride (BAC) is a quaternary ammonium compound (QAC) with a C8 to C18 chain length of alkyl groups. Since BAC exerts toxic effects on microorganisms, it has been used as an effective germicide and preservative, mostly in cosmetic industry and medicine. However, the toxic potential of BAC may b...
journal_title：International journal of occupational medicine and environmental health
pub_type： 杂志文章
doi：10.2478/v10001-008-0020-1
更新日期：2008-01-01 00:00:00
abstract：:Isoprostanes are a recently discovered group of prostaglandin isomers. Results of previous studies suggest that they can be used as oxidative stress markers, because in a number of cardiovascular, pulmonary and neurological diseases their levels in biological samples considerably increase. It has been found that peopl...
journal_title：International journal of occupational medicine and environmental health
pub_type： 杂志文章,评审
doi：10.13075/ijomeh.1896.00596
更新日期：2016-01-01 00:00:00
abstract：:Mice were administered with chloroform at 10 a.m., 2 p.m. and 6 p.m. and the signs of hepatotoxicity were measured 18 or 24 hrs later. The levels of alanine aminotransferase (ALT) in serum, and malondialdehyde (MDA) in the liver were higher after the evening administration compared to the morning one. The decrements o...
journal_title：International journal of occupational medicine and environmental health
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
abstract：OBJECTIVES:The objective of our study was to examine the impact of income, education chronic diseases and self-rated health on health behavior (smoking, alcohol consumption, physical activity, diet) in a large urban population of Poland. MATERIALS AND METHODS:The data were collected in Lódź, a large industrial city of...
journal_title：International journal of occupational medicine and environmental health
pub_type： 杂志文章
doi：
更新日期：2004-01-01 00:00:00
abstract：:The authors studied 140 women, selected at random, aged 22-55, divided into two groups. Group I (control) included 50 women, mean age 40.1 +/- 1.7 years. Group II included 90 women, mean age 39.7 +/- 2.1 years, chronically exposed to 15.6 - 21.84 mg/m3 of carbon disulphide from 0.5 to over 20 years. It was found that ...
journal_title：International journal of occupational medicine and environmental health
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
abstract：OBJECTIVES:The aim of this study was to evaluate the potential association between occupational stress and musculoskeletal symptoms in firefighters. MATERIAL AND METHODS:Data were collected among Cypriot firefighters through a battery of adapted questionnaires completed anonymously. RESULTS:A total of 430 firefighter...
journal_title：International journal of occupational medicine and environmental health
pub_type： 杂志文章
doi：10.13075/ijomeh.1896.01268
更新日期：2019-06-14 00:00:00
abstract：OBJECTIVES:The aim of this study is to assess chromosomal damage in Tunisian hospital workers occupationally exposed to low levels of ionizing radiation (IR). MATERIALS AND METHODS:The cytokinesis-block micronucleus (CBMN) assay in the peripheral lymphocytes of 67 exposed workers compared to 43 controls matched for ge...
journal_title：International journal of occupational medicine and environmental health
pub_type： 杂志文章,多中心研究
doi：10.2478/s13382-013-0084-4
更新日期：2013-03-01 00:00:00
abstract：OBJECTIVE:One of the practical models for assessment of stressful working conditions due to job strain is "job demand and control" or Karasek's job strain model. This model explains how adverse physical and psychological effects including cardiovascular disease risk factors can be established due to high work demand. T...
journal_title：International journal of occupational medicine and environmental health
pub_type： 杂志文章
doi：10.2478/s13382-013-0127-x
更新日期：2013-08-01 00:00:00
abstract：:Many etiologies are held accountable for nasal septum perforations. Topical nasal drug usage, previous surgeries, trauma, nose picking, squamous cell carcinoma, some rheumatological disorders such as granulomatosis with polyangiitis (Wegener granulomatosis), some infectious diseases such as syphilis and leprosy are am...
journal_title：International journal of occupational medicine and environmental health
pub_type：
doi：10.13075/ijomeh.1896.01019
更新日期：2017-10-06 00:00:00
abstract：OBJECTIVES:The method for the determination of As, Al, Cd, Ni, Pb (toxic elements) and Cr, Co, Cu, Fe, Mn, Zn (essential elements) in human urine by the use of Inductively Coupled Plasma Mass Spectrometry (quadrupole ICP-MS DRCe Elan, Perkin Elmer) with the dynamic reaction cell (DRC) was developed. MATERIALS AND METH...
journal_title：International journal of occupational medicine and environmental health
pub_type： 杂志文章
doi：10.2478/s13382-013-0106-2
更新日期：2013-04-01 00:00:00
abstract：OBJECTIVES:The main objective of this study has been qualitative investigation of the effects of external loading on the lumbar extension moment during squat lifting. Findings of this study may allow to determine the factor with the most considerable effect on the lumbar extension moment and may help determine the lumb...
journal_title：International journal of occupational medicine and environmental health
pub_type： 杂志文章
doi：10.13075/ijomeh.1896.00896
更新日期：2017-06-19 00:00:00
abstract：BACKGROUND:Children from low-income families may be subject to high exposures to polycyclic aromatic hydrocarbons (PAH) which can lead to respiratory disorders. This study aims to establish methods for assessing total PAH exposure of asthmatic and non-asthmatic children from low-income families; to estimate serum PAH c...
journal_title：International journal of occupational medicine and environmental health
pub_type： 杂志文章
doi：10.2478/v10001-008-0021-0
更新日期：2008-01-01 00:00:00
abstract：OBJECTIVES:This article investigates sickness presence among secondary school students in 5 European countries. The research questions asked are: What characterizes students with high sickness presence in secondary schools? Does high sickness presence influence future sickness absence? MATERIAL AND METHODS:A group of ...
journal_title：International journal of occupational medicine and environmental health
pub_type： 杂志文章
doi：10.13075/ijomeh.1896.01441
更新日期：2019-11-15 00:00:00
abstract：OBJECTIVES:The aim of this study was to investigate the cyto- and genotoxicity of nanocomposites (NCs) and generation of reactive oxygen species (ROS) as a result of particle-cell interactions. MATERIALS AND METHODS:Titanium dioxide (TiO(2)-Ag) and ion-exchange resin (Res-Ag), both coated with silver (Ag), were examin...
journal_title：International journal of occupational medicine and environmental health
pub_type： 杂志文章
doi：10.2478/s13382-011-0041-z
更新日期：2011-12-01 00:00:00
abstract：:Acute inflammatory lung injury is often a delayed complication of critical illness and is associated with increased mortality. High mobility group box 1 (HMGB1) protein, in addition to its role as a transcriptional regulator factor, has been identified as a late mediator of endotoxin lethality and might be also involv...
journal_title：International journal of occupational medicine and environmental health
pub_type： 杂志文章,评审
doi：
更新日期：2004-01-01 00:00:00
abstract：:An outline of the structure and operation principles of the database on EMF-producing devices used in Poland at frequencies ranging between 0.1 MHz and 300,000 MHz have been developed at the Nofer Institute of Occupational Medicine, Lodz. The primary objective of developing the EMF DATABASE is to ensure continuous and...
journal_title：International journal of occupational medicine and environmental health
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：:In the noisy environment, workers use hearing protectors to protect their hearing organ against adverse effects of noise. Hearing protectors should be well selected according to the spectrum and level of noise. The selection of hearing protectors is based on the sound attenuation values measured in laboratory conditio...
journal_title：International journal of occupational medicine and environmental health
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：OBJECTIVES:The aim of this study was to investigate the prevalence of obesity, alcoholic beverage consumption, unhealthy alcohol use and sudden sleep onset at the wheel among Italian truck drivers. In addition to prevalence rates, this study also aimed at investigating potential predictors for sudden-onset sleepiness a...
journal_title：International journal of occupational medicine and environmental health
pub_type： 杂志文章
doi：10.13075/ijomeh.1896.00638
更新日期：2016-01-01 00:00:00
abstract：:The authors aimed to characterize the current evidence base regarding musicians' musculoskeletal symptoms (MSS), in order to identify gaps for future research. A systematic search was conducted to identify peer-review studies published in English in 2007-2016 that investigated musicians' MSS. Narrative reviews, case r...
journal_title：International journal of occupational medicine and environmental health
pub_type： 杂志文章
doi：10.13075/ijomeh.1896.01340
更新日期：2019-06-14 00:00:00
abstract：:The role of glutathione S-transferase Mu 1 (GSTM1) in the biomonitoring of polycyclic aromatic hydrocarbons (PAHs) is not clear. Our purpose has been to evaluate the influence of GSTM1 genotypes on 1-hydroxypyrene (1-OHP), deoxyribonucleic acid (DNA) adducts, and micronucleus frequency in both occupational and non-occ...
journal_title：International journal of occupational medicine and environmental health
pub_type： 杂志文章,meta分析,评审
doi：10.13075/ijomeh.1896.01054
更新日期：2017-03-30 00:00:00
abstract：OBJECTIVES:Panic behavior poses a particular threat to the health and safety of subaquatic occupational specialists. Trait anxiety has previously been identified as a marker of panic behavior under water, and Spielberger's State-Trait Personality Inventory (trait anxiety subscale) has been previously used to measure tr...
journal_title：International journal of occupational medicine and environmental health
pub_type： 杂志文章
doi：10.2478/s13382-014-0321-5
更新日期：2014-12-01 00:00:00
