Abstract:
OBJECTIVE:To test models of unidirectional and bidirectional change between treatment adherence and glycemic control in youth with type 1 diabetes. RESEARCH DESIGN AND METHODS:We conducted a 2-year longitudinal, multisite study of 225 youth with type 1 diabetes recruited at the cusp of adolescence (aged 9-11 years) to describe the mutual influences of glycemic control as measured by HbA(1c) and treatment adherence as measured by blood glucose monitoring frequency (BGMF) during the transition to adolescence. RESULTS:HbA(1c) increased from 8.2 to 8.6% (P < 0.001) and BGMF decreased from 4.9 to 4.5 checks per day (P < 0.02) during the 2-year period. Changes in the BGMF slope predicted changes in HbA(1c). A change (increase) in HbA(1c) was associated with a change (decrease) in BGMF of 1.26 (P < 0.001) after controlling for covariates. CONCLUSIONS:The magnitude of the effect of declining treatment adherence (BGMF) on glycemic control in young adolescents may be even greater than declines observed among older adolescents. BGMF offers a powerful tool for targeted management of glycemic control for type 1 diabetes during the critical transition to adolescence.
journal_name
Diabetes Carejournal_title
Diabetes careauthors
Rausch JR,Hood KK,Delamater A,Shroff Pendley J,Rohan JM,Reeves G,Dolan L,Drotar Ddoi
10.2337/dc11-2163subject
Has Abstractpub_date
2012-06-01 00:00:00pages
1219-24issue
6eissn
0149-5992issn
1935-5548pii
dc11-2163journal_volume
35pub_type
杂志文章,多中心研究相关文献
DIABETES CARE文献大全abstract:OBJECTIVE:To investigate the triglyceride-glucose (TyG) index association with coronary artery calcification (CAC) progression in adult Koreans. RESEARCH DESIGN AND METHODS:Various cardiovascular risk factors and anthropometric profiles were assessed in 1,175 subjects who previously had a CAC evaluation at least twice...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc18-1920
更新日期:2019-08-01 00:00:00
abstract::Core Outcome Sets (COS) contain an agreed minimum set of outcomes to be measured and reported in all studies in a specific area, with the objective of standardizing outcome reporting. COS may minimize research waste by identifying outcomes important to key stakeholders, allowing for improved evidence synthesis, and fa...
journal_title:Diabetes care
pub_type: 杂志文章,评审
doi:10.2337/dc20-1621
更新日期:2020-12-01 00:00:00
abstract::OBJECTIVE To assess the relationship between albuminuria, including elevation within the normal range, and decline in glomerular filtration rate (GFR) in diabetic patients. RESEARCH DESIGN AND METHODS A total of 5,449 Japanese diabetic patients were categorized according to sex and urinary albumin-to-creatinine ratio ...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc08-2151
更新日期:2009-08-01 00:00:00
abstract:OBJECTIVE:Growth deferentiation factor-15 (GDF-15) is involved in inflammation and apoptosis. Expression is induced in the heart in response to ischemia and in atherosclerotic plaques. The aim of this study was to investigate GDF-15 levels in relation to all-cause mortality, cardiovascular mortality and morbidity, decl...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc09-2174
更新日期:2010-07-01 00:00:00
abstract:OBJECTIVE:The prevalence of the metabolic syndrome, a potent risk factor for cardiovascular diseases (CVDs), has not been adequately explored in older individuals. Moreover, two sets of criteria have been proposed for the definition of metabolic syndrome, one by the World Health Organization (WHO) and one by the Nation...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.28.4.882
更新日期:2005-04-01 00:00:00
abstract:OBJECTIVE:To determine whether overweight Latino children with impaired fasting glucose (IFG) (> or = 100 mg/dl) have increased insulin resistance or decreased beta-cell function compared with those with normal fasting glucose (NFG). RESEARCH DESIGN AND METHODS:We studied 207 healthy overweight Latino children, aged 8...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.28.10.2519
更新日期:2005-10-01 00:00:00
abstract:OBJECTIVE:To examine mortality rates and causes of death among subjects diagnosed with type 1 diabetes aged journal_title:Diabetes care pub_type: 杂志文章 doi:10.2337/dc07-2029 更新日期:2008-05-01 00:00:00
abstract::Whereas self-monitoring of blood glucose (SMBG) is the recommended source of information on which to make self-care decisions, patients frequently use estimates of their own blood glucose (BG). This study evaluated whether patients with insulin-dependent diabetes mellitus (IDDM) could learn to improve accuracy of BG e...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.12.5.313
更新日期:1989-05-01 00:00:00
abstract:OBJECTIVE:To compare the efficacy and safety of glimepiride versus metformin in pediatric subjects with type 2 diabetes inadequately controlled with diet and exercise alone or oral monotherapy. RESEARCH DESIGN AND METHODS:This 26-week, single-blind, active-controlled, multinational study randomized 285 subjects to rec...
journal_title:Diabetes care
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.2337/dc06-1554
更新日期:2007-04-01 00:00:00
abstract:OBJECTIVE:Longitudinal changes in GAD antibody (Ab) and ICA512/IA-2 (ICA512) Ab were examined in relation to age at the onset of diabetes and autoimmunity against the thyroid gland. RESEARCH DESIGN AND METHODS:GADAb, ICA512Ab, and antithyroid autoantibody were examined at onset in 40 juvenile-onset IDDM patients (17 m...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.21.1.49
更新日期:1998-01-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to examine the association of physical activity and cardiovascular fitness (CVF) with insulin sensitivity in a nationally representative sample of U.S. youth. RESEARCH DESIGN AND METHODS:The study included 1,783 U.S. adolescents (11% Mexican American, 14% non-Hispanic black, 63%...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc06-0426
更新日期:2006-07-01 00:00:00
abstract:OBJECTIVE:Existing physical examination scoring systems for distal diabetic polyneuropathy (PNP) do not fulfill all of the following criteria: validity, manageability, predictive value, and hierarchy The aim of this study was to adapt the Neuropathy Disability Score (NDS) to diagnose PNP in diabetes so that it fulfills...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.23.6.750
更新日期:2000-06-01 00:00:00
abstract::We studied the reliability of the Chemstrip system in the self-monitoring of blood glucose by diabetic patients. A total of 453 blood glucose values obtained by 38 diabetic patients using Chemstrip were compared with the glucose values of the same blood samples measured with a conventional laboratory method. We found ...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.4.3.414
更新日期:1981-05-01 00:00:00
abstract::To evaluate the importance of dialysis in the determination of glycosylated hemoglobin (HbA1), we studied blood glucose and HbA1 in 38 insulin-dependent diabetic children during a morning fast and again 6 h postprandially. We used two methods to determine glycosylated hemoglobin: (1) the conventional macrocolumn metho...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.4.5.551
更新日期:1981-09-01 00:00:00
abstract::This review summarizes Session IV: Therapeutic Interventions of the Fourth International Gestational Diabetes Workshop and suggests intervention protocols based on the presentations at this meeting and the literature. The opinions of the six presenters and their interpretation of the review of the literature in their ...
journal_title:Diabetes care
pub_type: 杂志文章,评审
doi:
更新日期:1998-08-01 00:00:00
abstract::Considerable attention has been focused on the importance of physical activity in improving the diabetic state in obese, non-insulin-dependent diabetic patients. Because this patient population tends to be sedentary, this challenge requires an active effort involving the patient and health-care providers. The latter m...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.3.5.627
更新日期:1980-09-01 00:00:00
abstract::Pancreatic beta cell responses were measured in obese and nonobese maturity-onset diabetes of the young (MODY) patients by estimating serum immunoreactive insulin (IRI) and C-peptide (CP) during oral glucose tolerance testing (OGTT). The serum CP responses were generally low in MODY patients and more pronounced in obe...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.8.1.69
更新日期:1985-01-01 00:00:00
abstract::A case-control study examining the 1-yr motor vehicle accident experiences of 158 insulin-dependent diabetes mellitus (IDDM) cases and 158 nondiabetic siblings was undertaken to evaluate the risk of motor vehicle accidents among drivers with IDDM. In multivariate analyses the overall accident risk of the cases and con...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.11.9.701
更新日期:1988-10-01 00:00:00
abstract:OBJECTIVE:A key milestone in progress towards providing an efficacious and safe closed-loop artificial pancreas system for outpatient use is the development of fully automated, portable devices with fault detection capabilities to ensure patient safety. The ability to remotely monitor the operation of the closed-loop s...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc12-0761
更新日期:2012-11-01 00:00:00
abstract:OBJECTIVE:To conduct a systematic review of the published literature on the efficacy and safety of herbal therapies and vitamin/mineral supplements for glucose control in patients with diabetes. RESEARCH DESIGN AND METHODS:We conducted an electronic literature search of MEDLINE, OLDMEDLINE, Cochrane Library Database, ...
journal_title:Diabetes care
pub_type: 杂志文章,评审
doi:10.2337/diacare.26.4.1277
更新日期:2003-04-01 00:00:00
abstract:OBJECTIVE:Physical activity is integral to the management of type 2 diabetes. Unfortunately, the majority of adults with type 2 diabetes do not regularly engage in physical activity. The purpose of this study was to assess physical activity behavior and its correlates (i.e., physical activity knowledge, barriers, and p...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.22.5.706
更新日期:1999-05-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to investigate the presence and correlates of clinically relevant cognitive impairment in middle-aged adults with childhood-onset type 1 diabetes (T1D). RESEARCH DESIGN AND METHODS:During 2010-2013, 97 adults diagnosed with T1D and aged <18 years (age and duration 49 ± 7 and 41 ± 6 ...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/dc15-0041
更新日期:2015-09-01 00:00:00
abstract::This study investigates and compares human insulin (recombinant DNA) and purified porcine insulin (PPI) in healthy volunteers and in type II diabetic patients, in terms of whether both these insulins were capable of influencing in a different manner pancreatic glucagon, C-peptide, and free fatty acids (FFA) concentrat...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.5.2.s93
更新日期:1982-11-01 00:00:00
abstract:OBJECTIVE:To compare the glycemic profiles of patients with type 1 diabetes treated with either an implantable insulin pump or pancreas or islet transplantation by the means of the continuous glucose monitoring system (CGMS; Minimed, Sylmar, CA). RESEARCH DESIGN AND METHODS:The CGMS enabled recording of subcutaneous g...
journal_title:Diabetes care
pub_type: 杂志文章,多中心研究
doi:10.2337/diacare.25.12.2256
更新日期:2002-12-01 00:00:00
abstract:OBJECTIVE:A large proportion of vulvovaginal candidiasis (VVC) in diabetes is due to non-albicans Candida species such as C. glabrata and C. tropicalis. Observational studies indicate that diabetic patients with C. glabrata VVC respond poorly to azole drugs. We evaluated the response to oral fluconazole and boric acid ...
journal_title:Diabetes care
pub_type: 杂志文章,随机对照试验
doi:10.2337/dc06-1469
更新日期:2007-02-01 00:00:00
abstract::OBJECTIVE-Impaired endothelial function of resistance and conduit arteries can be detected in patients with type 1 diabetes. We studied whether a persistent improvement of endothelial function can be achieved by regular physical training. RESEARCH DESIGN AND METHODS-The study included 26 patients with type 1 diabetes ...
journal_title:Diabetes care
pub_type: 临床试验,杂志文章
doi:10.2337/diacare.25.10.1795
更新日期:2002-10-01 00:00:00
abstract:OBJECTIVE:To compare pharmacokinetics (PK) and pharmacodynamics (PD) of insulin glargine in type 2 diabetes mellitus (T2DM) after evening versus morning administration. RESEARCH DESIGN AND METHODS:Ten T2DM insulin-treated persons were studied during 24-h euglycemic glucose clamp, after glargine injection (0.4 units/kg...
journal_title:Diabetes care
pub_type: 杂志文章,随机对照试验
doi:10.2337/dc14-0649
更新日期:2015-03-01 00:00:00
abstract::Diabetes mellitus is a major public health problem and a leading cause of death, disability, and cost in the United States. We review the epidemiology of diabetes and its complications, the costs of diabetes, and discuss intervention strategies to reduce the burden of diabetes in the United States. ...
journal_title:Diabetes care
pub_type: 杂志文章,评审
doi:10.2337/diacare.8.4.391
更新日期:1985-07-01 00:00:00
abstract:OBJECTIVE:Delayed gastric emptying and/or gastrointestinal symptoms occur in 30-50% of diabetic patients. Known contributing factors are autonomic neuropathy and acute hyperglycemia, but the role of gastric autoimmunity has never been investigated, although 15-20% of type 1 diabetic patients exhibit parietal cell antib...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.25.5.912
更新日期:2002-05-01 00:00:00
abstract::The purpose of the study was to assess the value of 24-h urinary estriols in the management of diabetic pregnancies. Twenty-seven pregnant diabetic patients (White's class B through R) received insulin dosages twice daily as a combination of NPH and regular insulin. Laboratory and home monitored blood glucose was main...
journal_title:Diabetes care
pub_type: 杂志文章
doi:10.2337/diacare.5.3.316
更新日期:1982-05-01 00:00:00