Diabetic neuropathy examination: a hierarchical scoring system to diagnose distal polyneuropathy in diabetes.

abstract：OBJECTIVE:To study the metabolic effect and the variability of the effect elicited by inhalation of 87.2 U insulin powder combined with an absorption enhancer. The metabolic effect was compared with that of 10.2 U regular insulin injected subcutaneously and of 5.5 U regular insulin given intravenously RESEARCH DESIGN ...

journal_title：Diabetes care

authors： Heinemann L,Klappoth W,Rave K,Hompesch B,Linkeschowa R,Heise T

更新日期：2000-09-01 00:00:00

abstract：OBJECTIVE:We sought to determine whether levels of inflammatory markers and different cytokines are abnormal in nondiabetic offspring of type 2 diabetic subjects. RESEARCH DESIGN AND METHODS:Cytokine levels were measured in 19 healthy control subjects and 129 offspring of patients with type 2 diabetes (109 with normal...

journal_title：Diabetes care

authors： Ruotsalainen E,Salmenniemi U,Vauhkonen I,Pihlajamäki J,Punnonen K,Kainulainen S,Laakso M

更新日期：2006-12-01 00:00:00

abstract：OBJECTIVE:Cardiomyopathy is noted in up to 40% of infants of diabetic mothers, and the exact mechanisms are unknown. The aim of this study was to determine whether fetal serum markers of cardiac function differ between normal and type 1 diabetic pregnancies and to examine the relationship between these markers and feta...

journal_title：Diabetes care

authors： Russell NE,Higgins MF,Amaruso M,Foley M,McAuliffe FM

更新日期：2009-11-01 00:00:00

abstract：OBJECTIVE:To determine the best autoantibody-based testing strategy for recruiting relatives for future intervention trials and to establish the role of islet cell antibodies (ICAs) within this strategy. RESEARCH DESIGN AND METHODS:ICAs, insulin autoantibodies (IAAs), GAD antibodies, and IA-2 antibodies were determine...

journal_title：Diabetes care

authors： Bingley PJ,Williams AJ,Gale EA

更新日期：1999-11-01 00:00:00

abstract：OBJECTIVE:With increasing life expectancy in the U.S., it is important to know whether a longer life expectancy means a longer healthy life span or a prolonged period of later-life morbidity. This study examines changes in lifetime without diabetes, a leading cause of morbidity in later life. RESEARCH DESIGN AND METHO...

journal_title：Diabetes care

authors： Cunningham SA,Riosmena F,Wang J,Boyle JP,Rolka DB,Geiss LS

更新日期：2011-10-01 00:00:00

abstract：OBJECTIVE:To compare the weight losses of black and white patients with NIDDM treated in a year-long behavioral weight loss program. RESEARCH DESIGN AND METHODS:Subjects were randomly assigned to a behavioral program that either used a low-calorie diet throughout or included two 12-week periods of a very-low calorie d...

journal_title：Diabetes care

authors： Wing RR,Anglin K

更新日期：1996-05-01 00:00:00

abstract：OBJECTIVE:To determine the prevalence and incidence of diabetes in Alaska Natives and the incidence of cerebrovascular accidents (stroke), myocardial infarction (MI), end-stage renal disease (ESRD), lower-extremity amputations (LEA), and mortality over a 6- to 8-year period. RESEARCH DESIGN AND METHODS:The data derive...

journal_title：Diabetes care

authors： Schraer CD,Adler AI,Mayer AM,Halderson KR,Trimble BA

更新日期：1997-03-01 00:00:00

abstract：OBJECTIVE:To assess the efficacy and safety of initial combination therapy with sitagliptin and metformin in patients with type 2 diabetes and inadequate glycemic control on diet and exercise. RESEARCH DESIGN AND METHODS:In a 24-week, randomized, double-blind, placebo-controlled, parallel-group study, 1,091 patients w...

journal_title：Diabetes care

authors： Goldstein BJ,Feinglos MN,Lunceford JK,Johnson J,Williams-Herman DE,Sitagliptin 036 Study Group.

更新日期：2007-08-01 00:00:00

abstract：OBJECTIVE:This study examined associations between BMI and mortality in individuals with normoglycemia, impaired fasting glucose (IFG), newly diagnosed diabetes, and prevalent diabetes and identified BMI ranges associated with the lowest mortality in each group. RESEARCH DESIGN AND METHODS:A total of 12,815,006 adults...

journal_title：Diabetes care

authors： Lee EY,Lee YH,Yi SW,Shin SA,Yi JJ

更新日期：2017-08-01 00:00:00

abstract：:Secondary failure to oral hypoglycemic agents (OHAs) is a possible outcome for non-insulin-dependent diabetes mellitus (NIDDM) patients and poses a serious therapeutic problem. In this study, we evaluated the effect of adding a single bedtime low-dose NPH insulin injection to the previous ineffective sulfonylurea ther...

journal_title：Diabetes care

authors： Trischitta V,Italia S,Borzi V,Tribulato A,Mazzarino S,Squatrito S,Vigneri R

更新日期：1989-09-01 00:00:00

abstract：OBJECTIVE:Screening involves the presumptive identification of asymptomatic individuals at increased risk for unrecognized disease. We examined changes in screening practices for prediabetes and diabetes since January 2010, when HbA1c was first recommended as an option for screening and diagnosis. RESEARCH DESIGN AND ...

journal_title：Diabetes care

authors： Evron JM,Herman WH,McEwen LN

更新日期：2019-04-01 00:00:00

abstract：OBJECTIVE:ABCC8 mutations cause neonatal diabetes mellitus that can be transient (TNDM) or, less commonly, permanent (PNDM); ∼90% of individuals can be treated with oral sulfonylureas instead of insulin. Previous studies suggested that people with ABCC8-PNDM require lower sulfonylurea doses and have milder neurological...

journal_title：Diabetes care

authors： Bowman P,Mathews F,Barbetti F,Shepherd MH,Sanchez J,Piccini B,Beltrand J,Letourneau-Freiberg LR,Polak M,Greeley SAW,Rawlins E,Babiker T,Thomas NJ,De Franco E,Ellard S,Flanagan SE,Hattersley AT,Neonatal Diabetes Internat

更新日期：2021-01-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of ginseng on newly diagnosed non-insulin-dependent diabetes mellitus (NIDDM) patients. RESEARCH DESIGN AND METHODS:In this double-blind placebo-controlled study, 36 NIDDM patients were treated for 8 weeks with ginseng (100 or 200 mg) or placebo. Efficacy was evaluated with psychoph...

journal_title：Diabetes care

authors： Sotaniemi EA,Haapakoski E,Rautio A

更新日期：1995-10-01 00:00:00

abstract：OBJECTIVE:Whether hyperglycemia in utero less than overt diabetes is associated with altered childhood glucose metabolism is unknown. We examined associations of gestational diabetes mellitus (GDM) not confounded by treatment with childhood glycemia in the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) cohort. RES...

journal_title：Diabetes care

authors： Lowe WL Jr,Scholtens DM,Kuang A,Linder B,Lawrence JM,Lebenthal Y,McCance D,Hamilton J,Nodzenski M,Talbot O,Brickman WJ,Clayton P,Ma RC,Tam WH,Dyer AR,Catalano PM,Lowe LP,Metzger BE,HAPO Follow-up Study Cooperative Res

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVE:Many non-European ethnic groups have an increased risk for diabetes; however, the published literature demonstrates considerable uncertainty about the rates of diabetes complications among minority populations. The objective of this study was to determine the risks of cardiovascular complications and of morta...

journal_title：Diabetes care

authors： Shah BR,Victor JC,Chiu M,Tu JV,Anand SS,Austin PC,Manuel DG,Hux JE

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVE:Sustained excess BMI increases the risk of type 1 diabetes (T1D) in autoantibody-positive relatives without diabetes of patients. We tested whether elevated BMI also accelerates the progression of islet autoimmunity before T1D diagnosis. RESEARCH DESIGN AND METHODS:We studied 706 single autoantibody-positive...

journal_title：Diabetes care

authors： Ferrara-Cook C,Geyer SM,Evans-Molina C,Libman IM,Becker DJ,Gitelman SE,Redondo MJ,Type 1 Diabetes TrialNet Study Group.

更新日期：2020-03-01 00:00:00

abstract：:The plasma glucose and plasma free insulin profiles of six totally insulin-dependent diabetic patients were compared during periods of 4 days in hospital under a conventional insulin therapy (ICIT) comprising 4 daily injections of regular insulin and under continuous subcutaneous insulin infusion (CSII). Two profiles ...

journal_title：Diabetes care

authors： Buysschaert M,Marchand E,Ketelslegers JM,Lambert AE

更新日期：1983-01-01 00:00:00

abstract：:In a 10-yr prospective population study 406 subjects who were 70 yr old received an oral glucose tolerance test. Of these subjects 169 were retested at 80. Three sets of diagnostic criteria were evaluated, of which the WHO criteria are recommended for screening studies in this age group. The prevalences of diabetes me...

journal_title：Diabetes care

authors： Agner E,Thorsteinsson B,Eriksen M

更新日期：1982-11-01 00:00:00

abstract：OBJECTIVE:In a few previous studies, cardiovascular disease (CVD) risk factors (RFs) have been shown to predict diabetes. Our objective was to determine whether the presence of CVD RFs predict the eventual development of diabetes after controlling for known RFs, such as directly measured insulin resistance and obesity....

journal_title：Diabetes care

authors： D'Agostino RB Jr,Hamman RF,Karter AJ,Mykkanen L,Wagenknecht LE,Haffner SM,Insulin Resistance Atherosclerosis Study Investigators.

更新日期：2004-09-01 00:00:00

abstract：OBJECTIVE:Incidence of type 2 diabetes might be associated with preexisting hypertension. There is no information on whether incident diabetes is predicted by blood pressure control. We evaluated the hazard of diabetes in relation to blood pressure control in treated hypertensive patients. RESEARCH DESIGN AND METHODS:...

journal_title：Diabetes care

authors： Izzo R,de Simone G,Chinali M,Iaccarino G,Trimarco V,Rozza F,Giudice R,Trimarco B,De Luca N

更新日期：2009-05-01 00:00:00

abstract：OBJECTIVE:Given the role of gut microbiota in regulating metabolism, probiotics administered during pregnancy might prevent gestational diabetes mellitus (GDM). This question has not previously been studied in high-risk overweight and obese pregnant women. We aimed to determine whether probiotics (Lactobacillus rhamnos...

journal_title：Diabetes care

authors： Callaway LK,McIntyre HD,Barrett HL,Foxcroft K,Tremellen A,Lingwood BE,Tobin JM,Wilkinson S,Kothari A,Morrison M,O'Rourke P,Pelecanos A,Dekker Nitert M

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVE:Long-term implications of childhood obesity and BMI change over the life course for risk of type 2 diabetes remain uncertain. The objective was to establish whether there are effects on adult glucose metabolism of 1) sensitive periods of BMI gain or 2) long duration of overweight and obesity. RESEARCH DESIGN...

journal_title：Diabetes care

authors： Power C,Thomas C

更新日期：2011-09-01 00:00:00

abstract：OBJECTIVE:While there is growing evidence on the effectiveness of structured care for diabetic patients in trial settings, standard population level evaluations may misestimate intervention benefits due to patient selection. In order to account for potential biases in measuring intervention benefits, we tested the impa...

journal_title：Diabetes care

authors： Chevreul K,Brunn M,Cadier B,Nolte E,Durand-Zaleski I

更新日期：2014-07-01 00:00:00

abstract：:OBJECTIVE We evaluated relationships of oral glucose tolerance testing (OGTT)-derived measures of insulin sensitivity and pancreatic β-cell function with indices of diabetes complications in a cross-sectional study of patients with type 2 diabetes who are free of overt cardiovascular or renal disease. RESEARCH DESIGN ...

journal_title：Diabetes care

authors： Mulvey CK,McNeill AM,Girman CJ,Churchill TW,Terembula K,Ferguson JF,Shah R,Mehta NN,Qasim AN,Rickels MR,Reilly MP

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:Adverse microbial exposures might contribute to diabetogenesis. We hypothesized that clinical periodontal disease (a manifestation of microbial exposures in dysbiotic biofilms) would be related to insulin resistance among diabetes-free participants. The roles of inflammatory mediation and effect modification ...

journal_title：Diabetes care

authors： Demmer RT,Squillaro A,Papapanou PN,Rosenbaum M,Friedewald WT,Jacobs DR Jr,Desvarieux M

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVE:To examine medical and mental health care expenditures for large numbers of individuals with diabetes enrolled in employment-sponsored insurance plans. RESEARCH DESIGN AND METHODS:Health insurance billing data for approximately 1.3 million individuals enrolled in health insurance plans sponsored by 862 large...

journal_title：Diabetes care

authors： Peele PB,Lave JR,Songer TJ

更新日期：2002-11-01 00:00:00

abstract：OBJECTIVE:Continuous glucose monitoring (CGM) reduces HbA1c and time spent in hypoglycemia in people with type 1 diabetes (T1D) treated with multiple daily insulin injections (MDI) when evaluated over shorter time periods. It is unclear to what extent CGM improves and helps to maintain glucose control, treatment satisf...

journal_title：Diabetes care

authors： Lind M,Ólafsdóttir AF,Hirsch IB,Bolinder J,Dahlqvist S,Pivodic A,Hellman J,Wijkman M,Schwarcz E,Albrektsson H,Heise T,Polonsky W

更新日期：2021-01-01 00:00:00

abstract：OBJECTIVE:To determine whether the use of glyburide is associated with an increased risk of cancer compared with the use of other second-generation sulfonylureas among patients with type 2 diabetes. RESEARCH DESIGN AND METHODS:The U.K. Clinical Practice Research Datalink was used to conduct a cohort study among 52,600...

journal_title：Diabetes care

authors： Tuccori M,Wu JW,Yin H,Majdan A,Azoulay L

更新日期：2015-11-01 00:00:00

abstract：OBJECTIVE:In a previous study, we found observational evidence of improvement in beta-cell function when rosiglitazone was added to a failing oral antihyperglycemic regimen consisting of sulfonylureas and metformin. To confirm our previous observations, we designed and performed a prospective, randomized, and controlle...

journal_title：Diabetes care

authors： Ovalle F,Bell DS

更新日期：2004-11-01 00:00:00

abstract：OBJECTIVE:Some children with type 1 diabetes may be at risk of cognitive impairments, but mechanisms of this effect have not been confirmed. The objective of this study was to determine whether severe hypoglycemia (SH) in children with type 1 diabetes is associated with cognitive decline over 18 months. RESEARCH DESIG...

journal_title：Diabetes care

authors： Wysocki T,Harris MA,Mauras N,Fox L,Taylor A,Jackson SC,White NH

更新日期：2003-04-01 00:00:00