Abstract：
:Treatment of bipolar disorder often results in patients taking several drugs in an attempt to alleviate residual depressive symptoms, which can lead to an accumulation of side effects. New treatments for bipolar depression that do not increase the side effect burden are needed. One nonpharmacological treatment with few side effects, bright light therapy, has been shown to be an effective therapy for seasonal affective disorder, yet has not been extensively studied for other forms of depression. Forty-four adults with bipolar disorder, depressed phase were randomized to treatment with bright light therapy, low-density or high-density negative ion generator for 8 weeks. The primary measure of efficacy was the Structured Interview Guide for the Hamilton Depression Rating Scale with Atypical Depression Supplement (SIGH-ADS). Adverse events were assessed using the Young Mania Rating Scale (YMRS) and Systematic Assessment for Treatment Emergent effects (SAFTEE). All outcome variables were statistically analyzed using a mixed model repeated measure analysis of variance (ANOVA). The results showed no statistically significant differences between groups in any outcome measures at study end point; adverse events, including switches into hypomania, were rare. Further research is needed to determine the efficacy of bright light therapy in this population.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Dauphinais DR,Rosenthal JZ,Terman M,DiFebo HM,Tuggle C,Rosenthal NEdoi
10.1016/j.psychres.2012.01.015subject
Has Abstractpub_date
2012-03-30 00:00:00pages
57-61issue
1eissn
0165-1781issn
1872-7123pii
S0165-1781(12)00045-5journal_volume
196pub_type
杂志文章,随机对照试验abstract：:Impulse Control Disorders (ICDs) are a set of behaviours characterised by impulsivity despite known harm. Related to ICDs is the dopamine dysregulation syndrome (DDS), which is characterised by an addiction-like consumption of dopaminergic medication and punding. These behaviours all have an increased prevalence in Pa...
journal_title：Psychiatry research
pub_type： 杂志文章,评审
doi：10.1016/j.psychres.2014.12.005
更新日期：2015-02-28 00:00:00
abstract：:Posttraumatic stress disorder (PTSD) is an anxiety- and memory-based disorder. The hippocampus and amygdala are key areas in mood regulation. Fluoxetine was found to improve the anxiety-related symptoms of PTSD patients. However, little work has directly examined the effects of fluoxetine on the hippocampus and the am...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.pscychresns.2015.02.011
更新日期：2015-05-30 00:00:00
abstract：:Baseline body mass index (BMI), baseline BMI status (normal, overweight, obese) and early (1 month) BMI increases were tested as predictors of 6- and 12-month increases in glucose and lipid measures in 82 olanzapine (OLZ)- and 78 risperidone (RIS)-treated patients with schizophrenia, schizoaffective disorder, or bipol...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2011.07.008
更新日期：2011-09-30 00:00:00
abstract：:Progressive supranuclear palsy (PSP) is a rare neurodegenerative disorder in which, classically, patients present with postural instability and falls, parkinsonism, and slowing of vertical saccades. PSP patients typically have deficits in cognitive functioning, difficulties with most daily activities, and present with...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2013.08.045
更新日期：2013-12-30 00:00:00
abstract：:Clearer understanding of psychological processes and mechanisms such as cognitive style inform more targeted psychological treatments for mood disorders. Studies to date have focused on bipolar I disorder or combined bipolar sub-types, precluding identification of any distinctive cognitive style profiles. We examined ...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2012.11.036
更新日期：2013-04-30 00:00:00
abstract：:Time perception (TP) impairment in schizophrenia has been originally described by clinicians and afterwards addressed in laboratory. Previous studies generally observed that schizophrenia patients overestimate time and that their timing sensitivity is impaired. However, because of the disease cognitive impairments, no...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2012.06.008
更新日期：2012-12-30 00:00:00
abstract：:We investigated the kinetic parameters of serotonin (5-HT) uptake into platelets in a group of 26 drug-naïve patients suffering from major depression before and after 3-7 weeks of treatment with citalopram. The degree of depression was rated using the Hamilton Depression Rating Scale (HDRS). The 5-HT uptake characteri...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2007.06.022
更新日期：2008-11-30 00:00:00
abstract：:This study aimed to examine the concurrent relation between six dimensions of emotion dysregulation, proposed by Gratz and Roemer (2004), and suicide ideation and attempt in a large sample of psychiatric adolescent inpatients. A sample of 547 adolescent inpatients completed measures on dimensions of emotion dysregulat...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2018.11.038
更新日期：2019-01-01 00:00:00
abstract：:Poor cognitive insight in schizophrenia has been linked to delusions, hallucinations, and negative symptoms as well as to depressive/anxiety symptoms. Its impact on quality of life has been less studied, especially in schizophrenia subjects with ongoing auditory hallucinations. The Beck Cognitive Insight Scale (BCIS) ...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2017.09.032
更新日期：2018-01-01 00:00:00
abstract：:The absence of assessment tools incorporating different cultural models of mental illness is a major barrier to recruiting ethnic minorities into clinical trials, reducing generalisability of findings and potentially increasing disparities in access to evidence-based care. This study aimed to develop and validate a ne...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2018.03.013
更新日期：2018-05-01 00:00:00
abstract：:Scores on 17 psychological dimensions of the Gottschalk-Gleser content analysis scales were obtained from 5-minute speech samples of 37 white children hospitalized on the psychiatric service of a general hospital. These content analysis scores were compared to identical scores obtained from a normative sample of 109 w...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(79)90030-1
更新日期：1979-07-01 00:00:00
abstract：:Wells's (2009) metacognitive theory suggests that inflexible and recurrent styles of thinking in response to negative thoughts, feelings, and beliefs underlie mood and anxiety symptoms. Wells termed such styles of thinking as the cognitive attentional syndrome (CAS). Using a clinical sample (N=132) of patients with ei...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2013.04.020
更新日期：2013-11-30 00:00:00
abstract：:Previous studies have shown that various factors, such as genetic and environmental factors, contribute to the development of major depressive disorder (MDD). The aim of this study is to clarify how multiple factors, including affective temperaments, childhood abuse and adult life events, are involved in the severity ...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2015.12.016
更新日期：2016-02-28 00:00:00
abstract：:The DSM-IV describes pathological gambling as a chronic condition with an insidious course. However, several extant studies characterize pathological and problem gambling as fluctuating over time. The present analyses expand on previous reports by evaluating changes in pathological gambling symptoms across the lifetim...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2006.05.015
更新日期：2007-07-30 00:00:00
abstract：:The cognitive significance of P300 abnormalities in schizophrenia and obsessive-compulsive disorder (OCD) was investigated. P300 was measured by an auditory oddball paradigm, in which a series of standard tones (1000 Hz) and target tones (1500 Hz) were presented. The subject's task was to count the number of the prese...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/s0925-4927(03)00045-3
更新日期：2003-06-30 00:00:00
abstract：:A range of executive function (EF) deficits have been associated with Borderline Personality (BPD), a disorder characterized by high rates of suicide. However, the role of EF and suicide risk in BPD has not been examined. This exploratory study compared working memory, Stroop interference, motor inhibition (SSRT) and ...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2011.10.008
更新日期：2012-03-30 00:00:00
abstract：:An exaggerated response to emotional stimuli is among the many symptoms widely reported by veterans of the 1991 Persian Gulf War. These symptomologies have been attributed to damage and dysfunction associated with deployment-related exposures. We collected event-related potential data from 22 veterans meeting Haley cr...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.pscychresns.2012.08.004
更新日期：2013-03-30 00:00:00
abstract：:In recent years, research focusing on childhood has reported that communication difficulties in autism spectrum disorder (ASD) are related to the social reciprocity difficulties inherent to ASD, as well as severe social anxiety and decreased verbal fluency. However, there have been no reports regarding these correlati...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2020.113503
更新日期：2020-12-01 00:00:00
abstract：:Orexins have played a role in reward-seeking and addiction-related behavior. There are few reports in the literature on serum levels of orexins in patients with heroin use disorder (HUD) undergoing methadone maintenance treatment (MMT). The aim of this study was to investigate the serum levels of orexin A in HUD patie...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2018.04.010
更新日期：2018-06-01 00:00:00
abstract：:Both the [3H]imipramine and [3H]paroxetine binding sites and the 5-HT2A receptor were simultaneously determined in frontal cortex, cingulate cortex, hippocampus and amygdala from 17 control subjects and 17 depressed suicide victims. A significant decrease in the maximum binding (Bmax) of [3H]imipramine was observed in...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/s0925-4927(98)00015-8
更新日期：1998-06-30 00:00:00
abstract：:Several existing laboratory-based stress paradigms have significant shortcomings for assessing neurobiological correlates of stress in healthy volunteers and severely ill psychiatric patients. We have examined neuroendocrine effects of stress associated with the lumbar puncture (LP) procedure in drug-free depressed an...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(88)90050-9
更新日期：1988-08-01 00:00:00
abstract：:Perception of objectively independent events or stimuli as being significantly connected and the associated proneness to perceive meaningful patterns constitute part of the positive symptoms of schizophrenia, which are associated with altered attentional processes in lateralized speech perception. Since perceiving mea...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2017.07.043
更新日期：2018-05-01 00:00:00
abstract：:The study objective was to develop a new measure for use in the empirical measurement of microaggression behaviors perpetrated towards persons with mental illness and examine its psychometric properties. Following development of an initial item pool, 505 participants (students at a large college in New York City and c...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2015.07.061
更新日期：2015-09-30 00:00:00
abstract：:Appropriately estimating stress levels in daily life is important for motivating people to undertake stress-management behaviors or seek out information on stress management and mental health. People who exhibit high stress underestimation might not be interested in information on mental health, and would therefore ha...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2017.12.090
更新日期：2018-04-01 00:00:00
abstract：:Borderline personality disorder (BPD) is a genetically influenced psychiatric illness with disruptions in neural systems supporting cognition and emotion regulation. Volumetric decreases of the hippocampus and amygdala may characterize BPD and serve as putative endophenotypes for the illness. The purpose of the presen...
journal_title：Psychiatry research
pub_type： 杂志文章,meta分析,评审
doi：10.1016/j.pscychresns.2012.02.012
更新日期：2012-03-31 00:00:00
abstract：:The Self-Regulatory Executive Function (s-REF) model assumes that a common set of unhelpful metacognitive beliefs have a central role in predisposition to psychological disorder and the maintenance of symptoms and distress. This research aims to test whether the five unhelpful metacognitive beliefs implicated in the m...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2016.10.029
更新日期：2016-12-30 00:00:00
abstract：:A computed tomographic (CT) brain scan study was conducted in 24 young males treated and followed up for hyperactivity since childhood. Compared to 27 matched controls, adults with a history of hyperactivity had a significantly greater frequency of cerebral atrophy. No differences in cerebellar atrophy frequency or in...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(86)90052-1
更新日期：1986-03-01 00:00:00
abstract：:The relationships between interrater diagnostic reliability, confidence in diagnosis, DSM-III-R criteria ambiguity and case report data quality were examined in 20 case vignettes describing psychosis-related symptomatology. Each of seven diagnosticians made DSM-III-R diagnoses and gave confidence ratings for those dia...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/s0165-1781(01)00223-2
更新日期：2001-04-15 00:00:00
abstract：:Utility is a measure of undesirability for a specific health state. This study determines the utility scores for the individual symptoms of depression, and examines the impact that personal experience with depression has on these scores. Seventy-five subjects (19 with current depression, 21 with past depression, and 3...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/s0165-1781(02)00097-5
更新日期：2002-06-01 00:00:00
abstract：:The major aims of this study were to examine how, if at all, having higher levels of PTSD would be associated with performance on a facial affect recognition task in which facial expressions of emotion are superimposed on emotionally valenced, non-face images. College students with trauma histories (N = 90) completed ...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2018.04.055
更新日期：2018-07-01 00:00:00
