Abstract：
:Utility is a measure of undesirability for a specific health state. This study determines the utility scores for the individual symptoms of depression, and examines the impact that personal experience with depression has on these scores. Seventy-five subjects (19 with current depression, 21 with past depression, and 35 healthy controls) assigned utility scores to each of 10 individual symptoms of depression, and three depression severity profiles. Utility scores were measured using the standard gamble technique. Mean utility scores were used to list the symptoms of depression from most to least undesirable. The three diagnostic groups were compared with respect to the magnitude of undesirability of the depressive symptoms. The results of this study found that individuals assigned different utility scores to different symptoms of depression. The psychological symptoms of depression such as suicidal ideation, guilt and depressed mood were ranked as more undesirable than the somatic symptoms of depression. Each diagnostic group ranked the symptoms of depression in a similar manner. Patients with a current depression were willing to accept a greater risk of death to avoid suffering from lifelong depressive symptoms as compared to patients with a past depression or healthy controls.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Schaffer A,Levitt AJ,Hershkop SK,Oh P,MacDonald C,Lanctot Kdoi
10.1016/s0165-1781(02)00097-5subject
Has Abstractpub_date
2002-06-01 00:00:00pages
189-97issue
2eissn
0165-1781issn
1872-7123pii
S0165178102000975journal_volume
110pub_type
杂志文章abstract：:Correlations between normalized regional cerebral metabolic rates for glucose, determined by positron emission tomography with 18F-2-fluoro-2-deoxy-D-glucose, were used to investigate functional associations between pairs of brain regions in 18 adult patients with primary obsessive-compulsive disorder (OCD) of childho...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0925-4927(91)90014-h
更新日期：1991-12-01 00:00:00
abstract：:Information is available on aripiprazole as a treatment for borderline personality disorder (BPD), but no data have yet been presented concerning the use of this drug as an adjunctive treatment for drug-resistant BPD patients. This study investigates aripiprazole augmentation of ongoing sertraline therapy in drug-resi...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2007.07.006
更新日期：2008-11-30 00:00:00
abstract：:Schizophrenic patients were carefully diagnosed and screened for a history of neurological disorders. Diagnosis and subtyping was based on DSM-III-R criteria, using the Structured Clinical Interview for DSM-III-R, which was administered by trained interviewers and confirmed by a research psychiatrist. The schizophreni...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(90)90104-d
更新日期：1990-01-01 00:00:00
abstract：:The main goal of this study it is explore the psychopathological differences between IPD and SIPD in a sample of 125 adults with a lifetime diagnosis of cocaine disorder recruited from treatment setting and through street contacts. A secondary analysis of six cross-sectional studies was conducted between 2000 and 2010...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2016.05.043
更新日期：2016-08-30 00:00:00
abstract：:Positron emission tomography with [18F]-fluoro-2-deoxy-D-glucose as tracer was used to investigate frontal glucose metabolism in 15 unmedicated schizophrenic patients and 15 healthy subjects under resting conditions. Although no difference in absolute frontal cerebral metabolic rates of glucose (CMRglu) were found bet...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0925-4927(95)02672-k
更新日期：1995-09-29 00:00:00
abstract：:We examined the impact of a mental health awareness campaign on public attitudes. The campaign was embedded in the project psychenet - Hamburg Network for Mental Health. Beliefs and attitudes were examined before and after specific awareness measures in Hamburg (intervention region) and Munich (control region). Analys...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2016.01.029
更新日期：2016-03-30 00:00:00
abstract：:Gambling disorder (GD) frequently co-occurs with substance use disorders. However, the extent to which GD co-occurs with behavioral addictions (BAs) and the demographic, clinical, and personality correlates of comorbid GD and BA is largely unknown. The aims of the present research were to address this gap among people...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2020.112763
更新日期：2020-02-01 00:00:00
abstract：:Comorbid depression is frequent in obsessive-compulsive disorder (OCD) and is acknowledged as a major confound in biological and neurocognitive investigations in OCD. The aim of the present study was to assess the distribution of depressive symptoms in a large OCD sample (n=162) and to analyze the dimensional structur...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2003.11.003
更新日期：2004-02-15 00:00:00
abstract：:Childhood maltreatment history is a prevalent risk factor for substance use disorder and has lifelong adverse consequences on psychiatric wellbeing. The role of personality variations in determining childhood maltreatment-associated outcomes is poorly understood. This study sought to test neuroticism and agreeableness...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2018.07.010
更新日期：2018-10-01 00:00:00
abstract：:Absence of the adhesio interthalamica (AI) in schizophrenic first episode patients is suggestive for another marker of early developmental neuropathologic changes. Moreover, findings suggest that schizophrenic patients without AI are characterised by more severe negative symptoms. The study aims to investigate the pre...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/s0925-4927(02)00044-6
更新日期：2002-10-01 00:00:00
abstract：:To clarify the relationship between serum folate and schizophrenia (SZ) risk, the meta-analysis was conducted. PubMed, Embase, and Web of Science were searched without language restrictions. Weighted mean difference (WMD) as a summary statistic was used in this meta-analysis. Subgroup analyses by publication language ...
journal_title：Psychiatry research
pub_type： 杂志文章,meta分析
doi：10.1016/j.psychres.2015.11.045
更新日期：2016-01-30 00:00:00
abstract：:The goal of the study was to describe with prospective methodology the therapeutic response to nortriptyline in the respiratory panic disorder (PD) subtype versus the non-respiratory subtype. A total of 118 PD outpatients (DSM-IV) were previously divided into respiratory (n=77) and non-respiratory (n=41) subtypes and ...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/s0165-1781(03)00132-x
更新日期：2003-10-15 00:00:00
abstract：:An exaggerated response to emotional stimuli is among the many symptoms widely reported by veterans of the 1991 Persian Gulf War. These symptomologies have been attributed to damage and dysfunction associated with deployment-related exposures. We collected event-related potential data from 22 veterans meeting Haley cr...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.pscychresns.2012.08.004
更新日期：2013-03-30 00:00:00
abstract：:Considering the lack of existing measures on attitudes toward personal recovery and the need to acknowledge the cultural milieu in recovery attitude assessment, the present study developed and validated the Attitudes towards Recovery Questionnaire (ARQ) in a sample of people in recovery of mental illness, family carer...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2018.05.047
更新日期：2018-09-01 00:00:00
abstract：:Poor cognitive insight in schizophrenia has been linked to delusions, hallucinations, and negative symptoms as well as to depressive/anxiety symptoms. Its impact on quality of life has been less studied, especially in schizophrenia subjects with ongoing auditory hallucinations. The Beck Cognitive Insight Scale (BCIS) ...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2017.09.032
更新日期：2018-01-01 00:00:00
abstract：:Numerous studies have implicated a connection between schizophrenia and autoimmune disorders. However, the precise relationship and underlying mechanism are still obscure. To further identify the association between autoimmune disorders and schizophrenia, the mRNA expressions of various cytokines and Toll-like recepto...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2010.04.049
更新日期：2011-05-30 00:00:00
abstract：:Objective measures of experimentally induced aggressiveness were evaluated in heroin-dependent patients (HDP), 15 receiving buprenorphine (BUP) and 15 receiving methadone (METH) treatment. HDP were randomly assigned to BUP and METH groups. Fifteen healthy subjects (CONT) were included in the study as controls. During ...
journal_title：Psychiatry research
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.psychres.2006.02.013
更新日期：2007-01-15 00:00:00
abstract：:In the search for a less expensive alternative to magnetic resonance imaging (MRI), which is contraindicated in some patients, we evaluated the accuracy of an individualized MR template-based head model in terms of navigated brain stimulation system targeting. The mean error between the identification of target points...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.pscychresns.2011.12.013
更新日期：2012-07-30 00:00:00
abstract：:Internet addiction became a major mental health problem in college student. Our objective was to examine the relationship between psychological inflexibility and experiential avoidance (PIEA) and Internet addiction (IA) and the mediating effects of mental health problem indicators. 500 college students (238 men and 26...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2017.07.021
更新日期：2017-11-01 00:00:00
abstract：:There have been conflicting findings as to whether the P3 brain potential to targets in oddball tasks is reduced in depressed patients. The P3 to novel distracter stimuli in a three-stimulus oddball task has a more frontocentral topography than P3 to targets and is associated with different cognitive operations and ne...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2008.10.023
更新日期：2009-12-30 00:00:00
abstract：:The most significant contributor to premature mortality in patients with bipolar disorder is preventable cardiovascular diseases. This study investigated if the Physical Activity Vital Sign (PAVS) assessment (two questions which clarify if a person meets the recommended 150min of physical activity per week) can identi...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2016.06.060
更新日期：2016-12-30 00:00:00
abstract：:Parental style and Cloninger's dimensions are associated with psychosis, but it is still unclear whether temperament, character and parenting variables are linked to specific psychotic symptoms. This study extends previous research exploring these issues. 78 patients with psychosis and 156 control subjects were recrui...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2018.08.066
更新日期：2018-11-01 00:00:00
abstract：:We have previously reported that the activity in platelets of the important antioxidant enzyme glutathione peroxidase (GPx) is inversely correlated with computed tomographic (CT) measures of brain atrophy in a population of patients with chronic schizophrenia, suggesting that low GPx may be a vulnerability factor in t...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(90)90103-c
更新日期：1990-01-01 00:00:00
abstract：:Antidepressants are widely used in treating depression and other behavioral problems in children and adolescents. Little is known about the long-term effects of these agents, particularly on physiological systems. The effects of previous antidepressant treatment during a social challenge in 9-month-old rhesus monkeys ...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/s0165-1781(00)00165-7
更新日期：2000-07-24 00:00:00
abstract：:We examined sex differences in the distribution of psychiatric diagnoses among hospitalized patients, controlling for socio-demographic variables. The sample included 1865 psychiatric inpatients consecutively admitted during a 9-year period. The finding of a higher proportion of men among patients hospitalized for sch...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2011.11.023
更新日期：2012-06-30 00:00:00
abstract：:This report describes a computer program for applying a new statistical method for determining levels of agreement, or reliability, when multiple examiners evaluate a single subject. The statistics that are performed include the following: an overall level of agreement, expressed as a percentage, that takes into accou...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/s0165-1781(97)00093-0
更新日期：1997-08-29 00:00:00
abstract：:No prospective studies of first psychotic episodes have explored sex differences in smoking cessation. The aim of this study was to determine the influence of sex and substance abuse on smoking cessation during an 8-year follow-up of patients after a first psychotic episode. Logistic regression modeling was used to id...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2011.08.005
更新日期：2012-01-30 00:00:00
abstract：:Concentrations of plasma norepinephrine (NE) and plasma-3-methoxy-4-hydroxyphenylglycol (MHPG), blood pressure, and heart rate were measured on 2 days in 25 depressed patients and 25 controls. Comparisons were made between patients and controls, and also between days for both groups, to determine the short-term stabil...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/0165-1781(86)90093-4
更新日期：1986-09-01 00:00:00
abstract：:The objectives of this study were to evaluate the oral health of a group of schizophrenic outpatients and a control group without psychiatric illness. The study also aimed to assess the influence of positive and negative symptomatology on oral health among outpatients with schizophrenia. The DMF-T Index (sum of decaye...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2010.09.012
更新日期：2011-06-30 00:00:00
abstract：:The mineralocorticoid receptor (Nr3c2) has received increased attention as an important stress-related gene. Here, we sought to uncover candidate genes regulating the expression of Nr3c2. Using a genetical genomics approach, we identified a significant trans-regulated expression quantitative trait locus (eQTL) at Chro...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2020.112760
更新日期：2020-01-07 00:00:00
