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Purification of Trypanosoma cruzi surface proteins involved in adhesion to host cells.

Abstract：

:We have identified four surface 83 kDa proteins of pI values 6.3, 6.4, 6.5 and 6.6 in T. cruzi trypomastigotes which specifically bind to rat heart myoblasts. These proteins were purified by isoelectric focusing and anion-exchange chromatography in an FPLC system. These 83 kDa proteins inhibit the attachment of trypomastigotes to myoblasts in a concentration-dependent manner, indicating that these trypomastigote proteins mediate the attachment of trypomastigotes to heart myoblasts.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Villalta F,Lima MF,Zhou L

doi

10.1016/0006-291x(90)90764-e

subject

Has Abstract

pub_date

1990-10-30 00:00:00

pages

925-31

issue

2

eissn

0006-291X

issn

1090-2104

pii

0006-291X(90)90764-E

journal_volume

172

pub_type

杂志文章

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