Abstract:
:Ovarian cancer in women is a complex and deadly disease, where the molecular events that initiate and control tumor formation remain poorly defined. Therefore, mouse models provide one approach for determining the mechanisms by which specific oncogenic factors cause ovarian surface epithelial cell and granulosa cell transformation. This minireview summarizes the phenotypes of current mouse models that have been generated and some of the underlying mechanisms they have provided.
journal_name
Endocrinologyjournal_title
Endocrinologyauthors
Mullany LK,Richards JSdoi
10.1210/en.2011-2121subject
Has Abstractpub_date
2012-04-01 00:00:00pages
1585-92issue
4eissn
0013-7227issn
1945-7170pii
en.2011-2121journal_volume
153pub_type
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