Do aspirin and statins prevent severe sepsis?

abstract：PURPOSE OF REVIEW:Hepatitis C virus is an RNA virus that usually establishes persistent infection in its host. As an important cause of cirrhosis and hepatocellular carcinoma worldwide, hepatitis C is a growing public health concern. Despite recent advances in therapy, most people infected with the virus can expect lif...

journal_title：Current opinion in infectious diseases

authors： Darling JM,Wright TL

更新日期：2004-06-01 00:00:00

abstract：PURPOSE OF REVIEW:In contrast to patients at risk for hospital-acquired pneumonia or mechanically ventilated patients at risk for ventilator-associated pneumonia, healthcare-associated pneumonia is a relatively new clinical entity that includes a spectrum of adult patients who have close association with acute care hos...

journal_title：Current opinion in infectious diseases

authors： Craven DE

更新日期：2006-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Pneumocystis pneumonia (PCP) is a frequent opportunistic infection associated with a high mortality rate. PCP is of increasing importance in non-HIV immunocompromised patients, who present with severe respiratory distress with low fungal loads. Molecular detection of Pneumocystis in broncho-alveolar l...

journal_title：Current opinion in infectious diseases

authors： Guegan H,Robert-Gangneux F

更新日期：2019-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Strict adherence to clinical practice guidelines is recognized to improve outcomes but the inconvenient truth is that only a small subset of what is done in medicine has been tested in appropriate, well designed studies. In this article, we aim to review controversial aspects of the clinical managemen...

journal_title：Current opinion in infectious diseases

authors： Peçanha-Pietrobom PM,Colombo AL

更新日期：2020-12-01 00:00:00

abstract：PURPOSE OF REVIEW:This review examines recent literature on Chagas disease in the immunosuppressed host. RECENT FINDINGS:Chagas disease in immunosuppressed patients may represent acute transmission in an organ recipient, or reactivation of chronic infection in an HIV-infected individual or patient receiving cardiac tr...

journal_title：Current opinion in infectious diseases

authors： Bern C

更新日期：2012-08-01 00:00:00

abstract：PURPOSE OF REVIEW:There is a global need for well tolerated, effective, and affordable vaccines to prevent group A streptococcal infections and their most serious complications. The aim of this review is to highlight the recent progress in the identification of promising vaccine antigens and new approaches to vaccine d...

journal_title：Current opinion in infectious diseases

authors： Dale JB,Walker MJ

更新日期：2020-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Integrase strand transfer inhibitors (INSTIs) have become a key component of antiretroviral therapy since the approval of twice-daily raltegravir in 2007 and the more recent approval of elvitegravir in 2012. At the same time, a third compound, dolutegravir, is in late-phase clinical trials, being test...

journal_title：Current opinion in infectious diseases

authors： Quashie PK,Mesplède T,Wainberg MA

更新日期：2013-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Fungal endocarditis remains a rare disease occurring mostly in patients with predisposing host conditions. Regarding its poor prognosis because of severe complications, there is an urgent need for properly established treatment guidelines and prophylaxis for patients at risk. In this review we provide...

journal_title：Current opinion in infectious diseases

authors： Tacke D,Koehler P,Cornely OA

更新日期：2013-12-01 00:00:00

abstract：:Herpes simplex virus persists in a latent form for the life of its host, periodically reactivating and often resulting in significant psychosocial distress for the patient. Currently no cure is available. Antiviral therapy is the main treatment modality, used either orally, intravenously, or topically to prohibit furt...

journal_title：Current opinion in infectious diseases

authors： Yeung-Yue KA,Brentjens MH,Lee PC,Tyring SK

更新日期：2002-04-01 00:00:00

abstract：PURPOSE OF REVIEW:This review addresses recent developments that relate to the pathogenesis of severe malaria and its treatment, and also highlights the increase in the global burden of malaria and provides a summary of clinical trials of malaria vaccines. RECENT FINDINGS:Malaria, one of the world's most important par...

journal_title：Current opinion in infectious diseases

authors： Maitland K,Bejon P,Newton CR

更新日期：2003-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Colonization of the host epithelia by pathogenic Escherichia coli is influenced by the ability of the bacteria to interact with host surfaces. Because the initial step of an E. coli infection is to adhere, invade, and persist within host cells, some strategies used by intestinal and extraintestinal E....

journal_title：Current opinion in infectious diseases

authors： Kalita A,Hu J,Torres AG

更新日期：2014-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The detection of latent tuberculosis infection (LTBI) in different categories of compromised patients is reviewed with focus on the role of strategies incorporating immunodiagnostic tests and analysis of epidemiological and clinical risk factors. RECENT FINDINGS:The development of active tuberculosis...

journal_title：Current opinion in infectious diseases

authors： Sauzullo I,Vullo V,Mastroianni CM

更新日期：2015-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Schistosomiasis is a chronic and morbid disease that affects hundreds of millions of the poorest individuals in (sub)tropical regions, particularly sub-Saharan Africa. Just one drug, praziquantel (PZQ), is available. As discussed, efforts to expand mass drug administration programs may accelerate the ...

journal_title：Current opinion in infectious diseases

authors： Caffrey CR,Secor WE

更新日期：2011-10-01 00:00:00

abstract：:The sequence of the Treponema pallidum genome was completed in July 1998, yielding a wealth of new information regarding the enigmatic spirochete that causes syphilis and related treponematoses. By providing the sequences and predicted functions of over 1000 genes, the genome sequence will greatly facilitate research ...

journal_title：Current opinion in infectious diseases

authors： Norris SJ,Weinstock GM

更新日期：2000-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Breast surgery is considered a clean surgical procedure; nevertheless, infection rates are often higher than those reported after other similarly considered clean surgeries (e.g., thyroid, hernia). Acute bacterial skin and soft tissue infections, mostly surgical site infections and implant-associated ...

journal_title：Current opinion in infectious diseases

authors： Corcione S,Lupia T,De Rosa FG

更新日期：2019-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Chronic pulmonary aspergillosis (CPA) is a relatively rare, slowly progressive pulmonary syndrome due to Aspergillus spp. that requires specific knowledge in terms of disease entity, diagnosis, management and azole resistance. This review focuses on the recent understanding of CPA entity and the emerg...

journal_title：Current opinion in infectious diseases

authors： Izumikawa K,Takazono T,Kohno S

更新日期：2010-12-01 00:00:00

abstract：PURPOSE OF REVIEW:This review focuses on recent developments on evaluation of 8-aminoquinoline analogs with broader efficacy and reduced toxicity, which would provide better drugs for treatment of protozoal infections. RECENT FINDINGS:The earlier efforts towards development of 8-aminoquinoline analogs have been direct...

journal_title：Current opinion in infectious diseases

authors： Tekwani BL,Walker LA

更新日期：2006-12-01 00:00:00

abstract：PURPOSE OF REVIEW:A review of recent developments in the understanding of the natural history of anal squamous carcinoma arising from areas of high-grade anal intraepithelial neoplasia. RECENT FINDINGS:Anal intraepithelial neoplasia is a consequence of chronic human papillomavirus infection in the anal canal and appea...

journal_title：Current opinion in infectious diseases

authors： Fox PA

更新日期：2006-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Japanese encephalitis is the most common vaccine-preventable viral encephalitis in Asia. In view of the production cessation of the inactivated mouse brain-derived Japanese encephalitis vaccine, it is timely to provide an update on new Japanese encephalitis vaccines and revised vaccine recommendations...

journal_title：Current opinion in infectious diseases

authors： Wilder-Smith A,Halstead SB

更新日期：2010-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Genital Chlamydia trachomatis is common among young, sexually active people. Infections are most often asymptomatic but have potential long-term consequences for female reproductive health. The link between C. trachomatis and ectopic pregnancy is mainly based on early seroepidemiological case-control ...

journal_title：Current opinion in infectious diseases

authors： Bakken IJ

更新日期：2008-02-01 00:00:00

abstract：PURPOSE OF REVIEW:This review addresses the changing patterns of antimicrobial resistance in Salmonella. RECENT FINDINGS:Resistance to chloramphenicol, amicillin and cotrimoxazole is common in Salmonella Typhi and Paratyphi A in Asia and a few countries of Africa. In some countries, the isolation of multidrug resistan...

journal_title：Current opinion in infectious diseases

authors： Parry CM

更新日期：2003-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The emergence of 2009 pandemic H1N1 influenza A (pH1N1) has provided a unique challenge to influenza control in healthcare settings. We provide an overview of the early lessons from the 2009 pandemic. RECENT FINDINGS:The modes of influenza transmission and their contributions to the development of in...

journal_title：Current opinion in infectious diseases

authors： Carlson AL,Budd AP,Perl TM

更新日期：2010-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The incidence of both invasive fungal infections and respiratory mould infections is increasing and they cause significant costs, morbidity and mortality. Non-Aspergillus moulds are increasing as cause of lung infections in specific populations and new problems of susceptibility and resistance are app...

journal_title：Current opinion in infectious diseases

authors： Paiva JA,Pereira JM

更新日期：2013-04-01 00:00:00

abstract：PURPOSE OF REVIEW:HIV postexposure prophylaxis is often recommended following potential sexual exposure to HIV. Recent data address the effectiveness of postexposure prophylaxis and prevention counseling, cost-effectiveness, antiretroviral options, challenges with nonoccupational postexposure prophylaxis among adolesce...

journal_title：Current opinion in infectious diseases

authors： Roland ME

更新日期：2007-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The present review describes the literature about the prevention of Staphylococcus aureus infections in surgery, published from August 2006 to January 2008, and puts it into perspective. RECENT FINDINGS:To prevent Staphylococcus aureus infections after surgical procedures, three methods were describe...

journal_title：Current opinion in infectious diseases

authors： van Rijen MM,Kluytmans JA

更新日期：2008-08-01 00:00:00

abstract：:Infections caused by Candida spp. are frequent and serious in oncology patients. Over the past decade, the introduction of azole antifungals as prophylactic agents, and other factors have caused a shift in the species of Candida that cause infection. During the period under review (June 1999 to June 2000), several stu...

journal_title：Current opinion in infectious diseases

authors： Marr KA

更新日期：2000-12-01 00:00:00

abstract：:Therapeutic approaches in the practice of haematology/oncology are increasing in complexity. Agents such as the purine analogues and monoclonal antibodies may introduce a new spectrum of infection as a consequence of prolonged/profound lymphoid suppression. The use of high dose therapy with stem cells support is incre...

journal_title：Current opinion in infectious diseases

authors： Potter M

更新日期：1999-08-01 00:00:00

abstract：:Efforts to reduce hospitalization or the length of stay are common topics in papers published last year. Chlamydia pneumoniae is now recognized worldwide as a common pathogen in community-acquired pneumonia. A great variation in the frequency of various pathogens is found in different countries, stressing the importan...

journal_title：Current opinion in infectious diseases

authors： Holmberg H

更新日期：1998-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The majority of hepatitis C virus (HCV) infections in the United Kingdom and many developing countries were acquired through injecting. New clinical guidance suggests that HCV treatment should be offered to people with a transmission risk - such as people who inject drugs (PWID) - irrespective of seve...

journal_title：Current opinion in infectious diseases

authors： Hickman M,De Angelis D,Vickerman P,Hutchinson S,Martin NK

更新日期：2015-12-01 00:00:00

abstract：:Cystic fibrosis is the most common lethal inherited disorder with autosomal recessive inheritance. Major progress has been made in understanding the molecular mechanisms leading to increased susceptibility to Pseudomonas aeruginosa colonization. Persistent respiratory infection with P. aeruginosa leads to progressive ...

journal_title：Current opinion in infectious diseases

authors： Brennan AL,Geddes DM

更新日期：2002-04-01 00:00:00