Relationship between prognosis of papillary thyroid carcinoma patient and age: a retrospective single-institution study.

abstract：:Antipituitary antibody (APA) has been reported to be detected in patients with autoimmune thyroid disease. Type 2 iodothyronine deiodinase (D2) is expressed in both pituitary gland and thyroid gland. We studied the association of APA and D2 peptide antibody in patients with autoimmune thyroid disease. Rat pituitary gl...

journal_title：Endocrine journal

authors： Nakahara R,Tsunekawa K,Yabe S,Nara M,Seki K,Kasahara T,Ogiwara T,Nishino M,Kobayashi I,Murakami M

更新日期：2005-12-01 00:00:00

abstract：:To explore the relationship between serum thyrotropin and components of metabolic syndrome in a Chinese cohort. A total of 1534 adult inhabitants in DaDong district of Shenyang were asked to fulfill the questionnaire, complete physical examination and OGTT. Blood samples were collected to test thyrotropin (TSH), fasti...

journal_title：Endocrine journal

authors： Lai Y,Wang J,Jiang F,Wang B,Chen Y,Li M,Liu H,Li C,Xue H,Li N,Yu J,Shi L,Bai X,Hou X,Zhu L,Lu L,Wang S,Xing Q,Teng X,Teng W,Shan Z

更新日期：2011-01-01 00:00:00

abstract：:This study aimed to assess the relationship between the metabolic effect after laparoscopic sleeve gastrectomy (LSG) in morbidly obese Japanese patients, with or without type 2 diabetes mellitus (T2DM), and improved pancreatic steatosis (PS). The study enrolled 27 morbidly obese Japanese patients who were undergoing L...

journal_title：Endocrine journal

authors： Umemura A,Sasaki A,Nitta H,Baba S,Ando T,Kajiwara T,Ishigaki Y

更新日期：2017-05-30 00:00:00

abstract：:It has been demonstrated the involvement of branched-chain amino acids (BCAA) on obesity and related metabolic disorder. We investigated the effects of branched-chain amino acids (BCAA) on obesity and on glucose/fat homeostasis in mice fed on a high-fat (45%) diet. BCAA was dissolved in 0.5% methylcellulose and added ...

journal_title：Endocrine journal

authors： Arakawa M,Masaki T,Nishimura J,Seike M,Yoshimatsu H

更新日期：2011-01-01 00:00:00

abstract：:An open-label prospective cross-over trial was performed to compare the efficacy and adverse effects of nateglinide with those of voglibose on Japanese early type 2 diabetes (who were oral hypoglycemic agent naïve and whose HbA(1C) levels were between 7.0 and 7.9% before treatment). Fourteen patients received 270 mg/d...

journal_title：Endocrine journal

authors： Kurebayashi S,Watada H,Tanaka Y,Kawasumi M,Kawamori R,Hirose T

更新日期：2006-04-01 00:00:00

abstract：:Therapeutic blocking antibodies against programmed death 1 (PD1) and cytotoxic T-lymphocyte antigen 4 (CTLA4) are applied for advanced cancer therapy, but induce a wide range of immune-related adverse events. In our recent case of a 52-year-old female doctor suffering from breast cancer having metastasized to the lung...

journal_title：Endocrine journal

authors： Okahata S,Sakamoto K,Mitsumatsu T,Kondo Y,Noso S,Ikegami H,Shiba T

更新日期：2019-04-25 00:00:00

abstract：:A nationwide epidemiologic survey of fibroblast growth factor 23 (FGF23)-related hypophosphatemic diseases was conducted in 2010 to clarify the prevalence and the clinical presentations of the disorders. A questionnaire inquiring the experience of patients with these diseases was sent to randomly selected hospitals th...

journal_title：Endocrine journal

authors： Endo I,Fukumoto S,Ozono K,Namba N,Inoue D,Okazaki R,Yamauchi M,Sugimoto T,Minagawa M,Michigami T,Nagai M,Matsumoto T

更新日期：2015-01-01 00:00:00

abstract：:Since accumulation and interaction of immune cells including T cells and monocytes/macrophages are involved in the processes of atherosclerosis, atherosclerosis is currently understood as an inflammatory disorder. Entrapment of extracellular matrices components such as hyaluronan by monocytes and macrophages, as well ...

journal_title：Endocrine journal

authors： Tabata T,Mine S,Okada Y,Tanaka Y

更新日期：2007-12-01 00:00:00

abstract：:Non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) and invasive encapsulated follicular variant of papillary thyroid carcinoma (EFV-PTC) are indistinguishable preoperatively. CD26 expression in follicular tumor-uncertain malignant potential (FT-UMP) is reported to be clearly higher t...

journal_title：Endocrine journal

authors： Takagi S,Hirokawa M,Nagashima K,Higuchi M,Kadota K,Ishikawa R,Sato M,Miyauchi A,Miyake Y,Haba R

更新日期：2020-12-28 00:00:00

abstract：:The aim of this study is to investigate glucose metabolism longitudinally during pregnancy to explore mechanisms underlying gestational diabetes mellitus (GDM). We reviewed a total of 62 pregnant Japanese women who underwent a 75g oral glucose tolerance test (OGTT) twice during pregnancy (median: early, 13; late, 28 w...

journal_title：Endocrine journal

authors： Saisho Y,Miyakoshi K,Ikenoue S,Kasuga Y,Matsumoto T,Minegishi K,Yoshimura Y,Itoh H

更新日期：2013-01-01 00:00:00

abstract：:To assess the total daily inulin dose (TDD) and contribution of basal insulin to TDD and to identify the predictive factors for insulin requirement profiles in subjects with type 2 diabetes, we retrospectively examined insulin requirement profiles of 275 hospitalized subjects treated with basal-bolus insulin therapy (...

journal_title：Endocrine journal

authors： Shimoda S,Okubo M,Koga K,Sekigami T,Kawashima J,Kukidome D,Igata M,Ishii N,Shimakawa A,Matsumura T,Motoshima H,Furukawa N,Nishida K,Araki E

更新日期：2015-01-01 00:00:00

abstract：:Diabetes mellitus complicated with insulin antibodies is rare in clinical practice but usually difficult to control. A high amount of insulin antibodies, especially with low affinity and high binding capacity, leads to unstable glycemic control characterized by hyperglycemia unresponsive to large volume of insulin and...

journal_title：Endocrine journal

authors： Hayashi A,Takano K,Kawai S,Shichiri M

更新日期：2016-01-01 00:00:00

abstract：:Metabolic syndrome is a common disorder in Taiwan. For this study 431 subjects were randomly selected from visitors to the Department of Health Management. Blood pressure, blood glucose, lipid, uric acid levels and anthropometric measurements with immunoreactive insulin (IRI) and leptin levels were all correlated. We ...

journal_title：Endocrine journal

authors： Chiou WK,Lin JD,Weng HF,Ou YC,Liu TH,Fang JT

更新日期：2005-02-01 00:00:00

abstract：:Fatigue is a common symptom in patients visiting the clinic of psychosomatic medicine. A 250-μg synthetic ACTH (1-24) test (rapid ACTH test) and Beck depression inventory (BDI) were performed for 62 patients presenting with fatigue who visited the Department of Psychosomatic Medicine at Fukuoka Tokushukai Hospital. Pa...

journal_title：Endocrine journal

authors： Matsubayashi S,Nakatake N,Hara T

更新日期：2020-01-28 00:00:00

abstract：:Synchronous associations of Cushing's syndrome (CS) and primary aldosteronism (PA) with multiple adrenocortical adenomas secreting each hormone independently have rarely been reported. Herein, we describe a unique case of PA associated with CS with detailed clinical and pathological investigations. Bilateral adrenal m...

journal_title：Endocrine journal

authors： Onoda N,Ishikawa T,Nishio K,Tahara H,Inaba M,Wakasa K,Sumi T,Yamazaki T,Shigematsu K,Hirakawa K

更新日期：2009-01-01 00:00:00

abstract：:Parathyroidectomy (PTX) is the standard treatment for secondary hyperparathyroidism (SHPT); however, the administration of cinacalcet has gained prominence as a noninvasive treatment. We aimed to determine whether PTX or cinacalcet is more effective in preventing morbidity and mortality through reviewing follow-up dat...

journal_title：Endocrine journal

authors： Kim WW,Rhee Y,Kim BS,Kim K,Lee CR,Kang SW,Lee J,Jeong JJ,Nam KH,Chung WY

更新日期：2019-10-28 00:00:00

abstract：:Adrenocortical carcinoma (ACC) is a rare aggressive tumor originating from adrenocortical parenchymal cells and its incidence is approximately 1 per million population per year. An oncocytic ACC is a recently identified entity among the several known histopathological variants of ACC, which is characterized by oncocyt...

journal_title：Endocrine journal

authors： Harada K,Yasuda M,Nakano Y,Yoshida K,Umeda Y,Yagi T,Yamazaki Y,Sasano H,Otsuka F

更新日期：2020-08-28 00:00:00

abstract：:Expression of activin A in fetal rat pancreas was studied immunohistochemically by using anti-activin A antibody. On embryonic day 12 (E12), cells in cap-like pancreatic anlage were stained with anti-activin A antibody. In these sections, no immunoreactive insulin or glucagon was observed. On E13.5, cells containing i...

journal_title：Endocrine journal

authors： Furukawa M,Eto Y,Kojima I

更新日期：1995-02-01 00:00:00

abstract：:The human endometrium undergoes cyclical changes including proliferation, differentiation, tissue breakdown, and shedding (menstruation) throughout a woman's reproductive life. The postovulatory rise in ovarian progesterone induces profound remodeling and differentiation of the estradiol-primed endometrium. This chang...

journal_title：Endocrine journal

authors： Maruyama T,Yoshimura Y

更新日期：2008-10-01 00:00:00

abstract：:Sera from 30 Japanese insulin-dependent diabetes mellitus (IDDM) patients of short duration were examined to determine whether they had antibodies to proteolytic fragments of islet antigen, the molecular weights of which were 37,000 and/or 40,000 Mr (37KAb). The median age and disease duration of the patients were 13 ...

journal_title：Endocrine journal

authors： Ozawa Y,Kasuga A,Maruyama T,Kitamura Y,Amemiya S,Ishihara T,Suzuki R,Saruta T

更新日期：1996-12-01 00:00:00

abstract：:Immunoglobulin G4-related disease (IgG4-RD) is characterized by elevated serum IgG4 levels, IgG4-positive plasmacytes, and lymphocyte infiltration into multiple organs. IgG4 thyroiditis is a subset of patients with Hashimoto's thyroiditis (HT) who exhibited histopathological features of IgG4-RD; its source of serum Ig...

journal_title：Endocrine journal

authors： Takeshima K,Ariyasu H,Inaba H,Inagaki Y,Yamaoka H,Furukawa Y,Doi A,Furuta H,Nishi M,Akamizu T

更新日期：2015-01-01 00:00:00

abstract：:We propose a new classification of thyroid follicular cell tumors which is correlated with patient's prognosis. It is unique as to two new categories: borderline malignancy between benign and malignant, and moderately differentiated adenocarcinoma (MDA) as a differentiation classification to stratify tumor aggressive...

journal_title：Endocrine journal

authors： Kakudo K,Bai Y,Liu Z,Li Y,Ito Y,Ozaki T

更新日期：2012-01-01 00:00:00

abstract：:The present study was undertaken to determine pathophysiology of body water control in hypernatremic subjects with hypothalamic space-occupying lesions. Eight subjects with hypothalamic space-occupying lesions were divided into two groups of hypernatremia in the presence or absence of body water deficit. In 5 dehydrat...

journal_title：Endocrine journal

authors： Hayashi T,Murata M,Saito T,Ikoma A,Tamemoto H,Kawakami M,Ishikawa SE

更新日期：2008-08-01 00:00:00

abstract：:Prostaglandin E2 (PGE2) has a potent bone resorbing activity in vitro, but some recent studies have shown that PGE2 stimulates bone formation in vivo. The effects of PGE2 on the bone are therefore still controversial. We attempted to reveal the effects of PGE2 on bone in vivo more directly; we injected PGE2 continuous...

journal_title：Endocrine journal

authors： Takada M,Yamamoto I,Yuu I,Kigami Y,Ohnaka Y,Morita R

更新日期：1995-06-01 00:00:00

abstract：:To determine whether patients with medullary thyroid carcinoma (MTC) develop other endocrine neoplasms or their relatives develop MTC, we investigated the mutations in the RET proto-oncogene in patients with multiple endocrine neoplasia type 2B (MEN 2B, N = 1) and sporadic MTC (N = 6). DNA from MTC tissue and the peri...

journal_title：Endocrine journal

authors： Migita M,Hiromatsu Y,Sato M,Yang D,Kameo J,Jimi A,Nonaka K

更新日期：1997-08-01 00:00:00

abstract：:Recent studies have revealed that decline in cellular nicotinamide adenine dinucleotide (NAD+) levels causes aging-related disorders and therapeutic approaches increasing cellular NAD+ prevent these disorders in animal models. The administration of nicotinamide mononucleotide (NMN) has been shown to mitigate aging-rel...

journal_title：Endocrine journal

authors： Irie J,Inagaki E,Fujita M,Nakaya H,Mitsuishi M,Yamaguchi S,Yamashita K,Shigaki S,Ono T,Yukioka H,Okano H,Nabeshima YI,Imai SI,Yasui M,Tsubota K,Itoh H

更新日期：2020-02-28 00:00:00

abstract：:Congenital adrenal hyperplasia (CAH) due to steroid 21-hydroxylase (21-OH) deficiency (21-OHD) is an autosomal recessive disorder, in which CYP21A2 mutations or deletions result in underproduction of glucocorticoid and mineralocorticoid, and overproduction of androgens. Patients with CAH are treated with oral steroid ...

journal_title：Endocrine journal

authors： Naiki Y,Miyado M,Horikawa R,Katsumata N,Onodera M,Pang S,Ogata T,Fukami M

更新日期：2016-10-29 00:00:00

abstract：:The proteins found in cow milk have been reported to cause systemic inflammation. Endoplasmic reticulum (ER) stress is known to be involved in the development of several metabolic disorders including insulin resistance and non-alcoholic fatty liver disease. However, the effect of thiazolidinediones (TZDs) on ER stress...

journal_title：Endocrine journal

authors： Kang SB,Kim HM,Kim HJ,Seok H,Huh JH,Lee BW,Kang ES,Lee HC,Cha BS

更新日期：2013-01-01 00:00:00

abstract：:In vitro studies in isolated pancreas and islets have shown that glucagon-like peptide-1 (GLP-1) promotes insulin release in a typical concentration-dependent manner. In contrast, the relationship between plasma GLP-1 and insulin concentrations in vivo is complicated, because GLP-1-promoted insulin release lowers bloo...

journal_title：Endocrine journal

authors： Eiki J,Yada T

更新日期：2011-01-01 00:00:00

abstract：:The effect of add-on therapy with sitagliptin on glycemic control was prospectively investigated in patients with type 2 diabetes mellitus (T2DM) receiving insulin alone or insulin combined with oral antidiabetic drugs. Seventy-one patients were evaluated (38 men and 33 women aged 63.9 ± 10.2 years). They were divided...

journal_title：Endocrine journal

authors： Katsuno T,Ikeda H,Ida K,Miyagawa J,Namba M

更新日期：2013-01-01 00:00:00