Expression of immunoreactive activin A in fetal rat pancreas.

abstract：:Thyrotropin-releasing hormone (TRH)-stimulated thyroid stimulating hormone (TSH) response in normal subjects is suppressed by oral glucose administration. Pharmacologic studies indicate that this suppressive action of glucose is mediated by an increase in hypothalamic somatostatin (SRIH) tone. Since activation of the ...

journal_title：Endocrine journal

authors： Park C,Kim E,Sohn S,Yang I,Koh G,Oh S,Woo J,Kim S,Kim J,Kim Y,Oh K,Park S,Park S

更新日期：2005-02-01 00:00:00

abstract：:Erdheim-Chester disease (ECD) is a form of non-Langerhans histiocytosis. In this report, we show a case of ECD presenting diabetes insipidus and multiple xanthogranulomas received glucocorticoid treatment over a year. During this period, xanthogranulomas improved in response to the glucocorticoid therapy. Furthermore,...

journal_title：Endocrine journal

authors： Taguchi T,Iwasaki Y,Asaba K,Yoshida T,Takao T,Ikeno F,Nakajima H,Kodama H,Hashimoto K

更新日期：2008-03-01 00:00:00

abstract：:Since 1989, neonatal mass screening for congenital adrenal hyperplasia (CAH) has been carried out in Japan. The mass screening has detected not only the patients with the classic form of steroid 21-hydroxylase deficiency (21-OHD), but also those with the nonclassic (NC) form of 21-OHD, and the molecular basis in these...

journal_title：Endocrine journal

authors： Shinagawa T,Horikawa R,Isojima T,Naiki Y,Tanaka T,Katsumata N

更新日期：2007-12-01 00:00:00

abstract：:The two types of prognostic factors of papillary thyroid carcinoma (PTC) are static and dynamic. The following static prognostic factors have been conventionally adopted: age, tumor size, extrathyroid extension, lymph node metastasis, and distant metastasis based on pre-, intra- and post-operative findings. These fact...

journal_title：Endocrine journal

authors： Ito Y,Miyauchi A,Kobayashi K,Kihara M,Miya A

更新日期：2014-01-01 00:00:00

abstract：:Metabolic syndrome (MetS) is the occurrence of diabetes mellitus/glucose intolerance, arterial hypertension, central obesity, dyslipidemia, and microalbuminuria in the same patient (definition by WHO). Presence of metabolic syndrome is associated with larger myocardial infarction size and complications following acut...

journal_title：Endocrine journal

authors： Kranjcec D,Altabas V

更新日期：2012-01-01 00:00:00

abstract：:In hope of understanding possible roles of estrogen during early embryogenesis, we examined the expression of both estrogen receptor alpha (ER alpha) and ER beta, a recently cloned novel subtype, in mouse oocytes and preimplantation embryos by means of reverse transcription polymerase chain reaction (RT-PCR). To inves...

journal_title：Endocrine journal

authors： Hiroi H,Momoeda M,Inoue S,Tsuchiya F,Matsumi H,Tsutsumi O,Muramatsu M,Taketani Y

更新日期：1999-02-01 00:00:00

abstract：:We studied the changes in serum sodium (Na) and potassium (K) levels in seventeen patients in diabetic ketoacidosis and nine patients in non-ketotic hyperosmolar coma, who had marked hyperglycemia (707.4 +/- 75.6 mg/dl, mean +/- SEM) and dehydration. The disorder characterized two types of alteration. The one group wa...

journal_title：Endocrine journal

authors： Ishikawa S,Sakuma N,Fujisawa G,Tsuboi Y,Okada K,Saito T

更新日期：1994-02-01 00:00:00

abstract：:Somatostatin is well known to inhibit the hormone secretion of various peptides. This action has been considered to be generally mediated via six different specific somatostatin receptors (sstr), sstr1, sstr2A, sstr2B, sstr3, sstr4, and sstr5. It then becomes very important to demonstrate the localization of these sst...

journal_title：Endocrine journal

authors： Taniyama Y,Suzuki T,Mikami Y,Moriya T,Satomi S,Sasano H

更新日期：2005-10-01 00:00:00

abstract：:This study assessed the association of muscle mass with insulin resistance, evaluated from the insulin sensitivity index (ISI), in Japanese patients with gestational diabetes mellitus (GDM). Consecutive patients with GDM (n = 96) admitted to St. Marianna University Hospital between October 2015 and March 2018 for init...

journal_title：Endocrine journal

authors： Kawanabe S,Nagai Y,Nakamura Y,Nishine A,Nakagawa T,Tanaka Y

更新日期：2019-01-28 00:00:00

abstract：:The gene responsible for multiple endocrine neoplasia type 1 (MEN1) has recently been cloned, and its germline mutations were identified in patients with this syndrome. The majority of the mutations, frameshift or nonsense mutations, are expected to result in a loss of function of the gene product menin. Since the con...

journal_title：Endocrine journal

authors： Miyauchi A,Sato M,Matsubara S,Ohye H,Kihara M,Matsusaka K,Nishitani A,Takahara J

更新日期：1998-12-01 00:00:00

abstract：:Thyroid dysfunction has been known to be closely associated with increased vascular events. The aims of the present study included determining the prevalence of subclinical thyroid disease and relationships between normal ranges of thyroid function and internal carotid artery steno-occlusion (ICS) in patients with isc...

journal_title：Endocrine journal

authors： Jeong SK,Seo JY,Nam HS,Park HK

更新日期：2010-01-01 00:00:00

abstract：:Patients with IgG4-related disease (IgG4-RD) are diagnosed in Japan by comprehensive or organ-specific diagnostic criteria. To date, organ-specific criteria have been established for several organs, but not for the thyroid. We attempted to establish diagnostic criteria for IgG4-related thyroid disease (IgG4-RTD) based...

journal_title：Endocrine journal

authors： Takeshima K,Li Y,Kakudo K,Hirokawa M,Nishihara E,Shimatsu A,Takahashi Y,Akamizu T

更新日期：2021-01-28 00:00:00

abstract：:We examined 13 patients with euthyroid Graves' disease suspected ophthalmologically, by comparing them with 20 patients with untreated Graves' disease and by following them up for 5 to 10 years. They had Graves' ophthalmopathy (NOSPECS class II-IV) without other ocular diseases, normal levels of serum thyroid hormones...

journal_title：Endocrine journal

authors： Kashiwai T,Tada H,Asahi K,Hidaka Y,Tamaki H,Iwatani Y,Amino N

更新日期：1995-06-01 00:00:00

abstract：:The management of occult small thyroid nodules found by ultrasonography is sometimes problematic. Self-palpation may be utilized in the follow-up of these nodules. We developed a method of thyroid self-examination (TSE). We examined the size of the nodules palpable by this method by ultrasonography. In 78 patients exa...

journal_title：Endocrine journal

authors： Takano T,Hasegawa Y,Amino N

更新日期：2000-10-01 00:00:00

abstract：:Synchronous associations of Cushing's syndrome (CS) and primary aldosteronism (PA) with multiple adrenocortical adenomas secreting each hormone independently have rarely been reported. Herein, we describe a unique case of PA associated with CS with detailed clinical and pathological investigations. Bilateral adrenal m...

journal_title：Endocrine journal

authors： Onoda N,Ishikawa T,Nishio K,Tahara H,Inaba M,Wakasa K,Sumi T,Yamazaki T,Shigematsu K,Hirakawa K

更新日期：2009-01-01 00:00:00

abstract：:This study aimed to assess the relationship between the metabolic effect after laparoscopic sleeve gastrectomy (LSG) in morbidly obese Japanese patients, with or without type 2 diabetes mellitus (T2DM), and improved pancreatic steatosis (PS). The study enrolled 27 morbidly obese Japanese patients who were undergoing L...

journal_title：Endocrine journal

authors： Umemura A,Sasaki A,Nitta H,Baba S,Ando T,Kajiwara T,Ishigaki Y

更新日期：2017-05-30 00:00:00

abstract：:Geographic differences have been reported to affect the morphological and molecular features of papillary thyroid carcinomas (PTCs). The area around Chernobyl is well-known to be iodine-deficient in contrast to Japan, an iodine-rich country. We reviewed histological differences in adult PTC between Ukraine and Japan. ...

journal_title：Endocrine journal

authors： Ito M,Bogdanova T,Zurnadzhy L,Saenko V,Rogounovitch T,Mitsutake N,Kondo H,Maeda S,Nakashima M,Tronko M,Yamashita S

更新日期：2014-01-01 00:00:00

abstract：:The incidence of noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) in papillary thyroid carcinoma (PTC) is significantly lower in Asian countries than Western countries; however, the difference remains unexplained. This study aimed to evaluate the incidence of NIFTP in tumors diagnos...

journal_title：Endocrine journal

authors： Hirokawa M,Higuchi M,Suzuki A,Hayashi T,Kuma S,Miyauchi A

更新日期：2020-10-28 00:00:00

abstract：:We previously developed a radioreceptor assay which is presumably specific for detection of blocking-type anti-TSH receptor (TSHR) antibodies using unsolubilized porcine TSHR. Employing this assay, we measured blocking TSH-binding inhibitory immunoglobulin (TBII) in the sera from 30 untreated Graves' patients and comp...

journal_title：Endocrine journal

authors： Tada H,Izumi Y,Watanabe Y,Takano T,Fukata S,Kuma K,Hidaka Y,Amino N

更新日期：2001-12-01 00:00:00

abstract：:The effect of add-on therapy with sitagliptin on glycemic control was prospectively investigated in patients with type 2 diabetes mellitus (T2DM) receiving insulin alone or insulin combined with oral antidiabetic drugs. Seventy-one patients were evaluated (38 men and 33 women aged 63.9 ± 10.2 years). They were divided...

journal_title：Endocrine journal

authors： Katsuno T,Ikeda H,Ida K,Miyagawa J,Namba M

更新日期：2013-01-01 00:00:00

abstract：:It has been suggested that metabolic syndrome (MetS) overlaps prediabetes and type 2 diabetes and that it is not necessary to consider it as a separate clinical entity. In the present study, patients with normoglycemia and dysglycemia were compared in terms of MetS frequency and MetS criteria characteristics, in order...

journal_title：Endocrine journal

authors： Uzunlulu M,Oguz A

更新日期：2007-12-01 00:00:00

abstract：:Prostaglandin E2 (PGE2) has a potent bone resorbing activity in vitro, but some recent studies have shown that PGE2 stimulates bone formation in vivo. The effects of PGE2 on the bone are therefore still controversial. We attempted to reveal the effects of PGE2 on bone in vivo more directly; we injected PGE2 continuous...

journal_title：Endocrine journal

authors： Takada M,Yamamoto I,Yuu I,Kigami Y,Ohnaka Y,Morita R

更新日期：1995-06-01 00:00:00

abstract：:We describe a patient with right adrenal tumor detected incidentally. The tumor was diagnosed as pheochromocytoma by endocrinological and radiological studies, and was removed surgically. Graves' disease, which had been in remission for more than two decades after discontinuation of antithyroid drug treatment, relapse...

journal_title：Endocrine journal

authors： Abe M,Mori K,Nagai K,Ito S

更新日期：2003-12-01 00:00:00

abstract：:TSH receptor antibody (TRAb) titer has been reported to be correlated with Graves' ophthalmopathy (GO). However, the correlation between GO activity and TRAb titer assessed with a third-generation assay has not been reported. We enrolled 238 untreated Graves' disease patients who came to the outpatient clinic of Ito H...

journal_title：Endocrine journal

authors： Mukasa K,Yoshimura Noh J,Kouzaki A,Ohye H,Kunii Y,Watanabe N,Yoshihara A,Matsumoto M,Suzuki M,Ito K

更新日期：2016-01-01 00:00:00

abstract：:Several studies have shown the correlation between vitamin D [25(OH)D] deficiency and thyroid autoimmunity and reducing of thyroid autoantibodies in patients with normal levels of vitamin D combining with thyroid hormone replacement. However, other authors not agree with this association. It is still unclear whether t...

journal_title：Endocrine journal

authors： Botelho IMB,Moura Neto A,Silva CA,Tambascia MA,Alegre SM,Zantut-Wittmann DE

更新日期：2018-10-29 00:00:00

abstract：:Plasma total homocysteine (tHcy) is an independent risk factor for cardiovascular disease and increased tHcy levels have been reported to be a novel risk factor of atherosclerotic disease. The aim of this study was to assess the association of the metabolic syndrome components with plasma (tHcy) level. Total 722 parti...

journal_title：Endocrine journal

authors： Rhee EJ,Hwang ST,Lee WY,Yoon JH,Kim BJ,Kim BS,Kang JH,Lee MH,Park JR,Sung KC

更新日期：2007-12-01 00:00:00

abstract：:The syndrome of McCune-Albright syndrome (MAS) is clasically defined as a triad presentation with the findings of polyostotic fibrous dysplasia, café-au-lait spots, and sexual precocity. However, not all patients present with complete symptoms. A 52-year-old man was diagnosed as having a variant of McCune-Albright syn...

journal_title：Endocrine journal

authors： Sargin H,Gozu H,Bircan R,Sargin M,Avsar M,Ekinci G,Yayla A,Gulec I,Bozbuga M,Cirakoglu B,Tanakol R

更新日期：2006-02-01 00:00:00

abstract：:Sirtuin1 (SIRT1) is activated during calorie restriction and appears to be related to energy balance through glucose or lipid metabolism and insulin signaling. These findings suggest that SIRT1 may play a role in the pathophysiology of visceral obesity. Therefore, we investigated the relationship between SIRT1 gene ex...

journal_title：Endocrine journal

authors： Lee H,Chu SH,Park JY,Park HK,Im JA,Lee JW

更新日期：2013-01-01 00:00:00

abstract：:Anaplastic carcinoma arises from differentiated carcinoma and generally shows a dire prognosis. Anaplastic transformation may occur not only in primary tumors but also in metastatic lymph nodes. We encountered 5 cases of papillary carcinoma showing anaplastic transformation in lymph nodes that were curatively resected...

journal_title：Endocrine journal

authors： Ito Y,Higashiyama T,Hirokawa M,Fukushima M,Inoue H,Yabuta T,Tomoda C,Uruno T,Kihara M,Takamura Y,Miya A,Kobayashi K,Matsuzuka F,Miyauchi A

更新日期：2008-12-01 00:00:00

abstract：:Circulating human GH (hGH) consists of several molecular isoforms. It was previously reported that the proportion of 20 kilodalton hGH (20K-hGH) was elevated in the serum of patients with active acromegaly. In this study, we investigated the effects of octreotide and transsphenoidal adenomectomy on the proportion of 2...

journal_title：Endocrine journal

authors： Murakami Y,Shimizu T,Yamamoto M,Kato Y

更新日期：2004-06-01 00:00:00