The role of βIII-tubulin in non-small cell lung cancer patients treated by taxane-based chemotherapy.

abstract：BACKGROUND:We conducted a phase I dose escalation study to determine the maximum tolerated dose (MTD), the recommended dose (RD) and the safety profile of amrubicin (AMR) plus paclitaxel (PTX) combination regimen for patients with previously treated non-small cell lung cancer (NSCLC). PATIENTS AND METHODS:PTX was admi...

journal_title：International journal of clinical oncology

authors： Kaira K,Sunaga N,Imai H,Kamide Y,Koga Y,Ono A,Kuwako T,Masuda T,Hisada T,Ishizuka T,Yamada M

更新日期：2016-04-01 00:00:00

abstract：:Research misconduct and fraud in clinical research is an increasing problem facing the scientific community. This problem is expected to increase due to discoveries in central statistical monitoring and with the increase in first-time clinical trial investigators in the increasingly global reach of oncology clinical t...

journal_title：International journal of clinical oncology

authors： Herson J

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Indocyanine green (ICG), an agent for measuring liver function, becomes fluorescent under near-infrared (NIR) light after binding to serum proteins. Hepatocellular carcinoma (HCC) with a deposit of preoperatively administered ICG becomes clearly detectable under ICG fluorography; however, it remains unclear ...

journal_title：International journal of clinical oncology

authors： Morita Y,Sakaguchi T,Unno N,Shibasaki Y,Suzuki A,Fukumoto K,Inaba K,Baba S,Takehara Y,Suzuki S,Konno H

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:Invasive micropapillary carcinoma (IMPC) is a relatively rare subtype of gastric adenocarcinoma and has aggressive histopathologic characteristics, including lymphatic and vascular invasion. However, the associated long-term survival outcomes remain unclear. This study aimed to compare the clinicopathologica...

journal_title：International journal of clinical oncology

authors： Kano M,Hihara J,Kaneko M,Uemura K,Ohge H,Sueda T

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Recent studies have shown that immune-related adverse events (irAEs) caused by immune checkpoint inhibitors (ICIs) were correlated with favorable clinical outcome in patients with melanoma. However, in metastatic renal cell carcinoma (mRCC) patients, there have been few reports about the correlation between ...

journal_title：International journal of clinical oncology

authors： Kato T,Nagahara A,Kawamura N,Nakata W,Soda T,Matsuzaki K,Hatano K,Kawashima A,Ujike T,Imamura R,Nishimura K,Takada S,Tsujihata M,Yamaguchi S,Takao T,Nishimura K,Nonomura N,Uemura M

更新日期：2021-01-20 00:00:00

abstract：:In Japan, the first actual survey of morbidity from cancer was conducted by Dr. Mitsuo Segi in Miyagi Prefecture from 1951 to 1953. Population-based cancer registries were started in 1957 in Hiroshima and 1958 in Nagasaki for the follow-up of survivors of the atomic bombings. Public population-based cancer registries,...

journal_title：International journal of clinical oncology

authors： Okamoto N

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:To report on our primary experience with the placement of a hydrogel spacer following stereotactic body radiation therapy (SBRT) in low- and intermediate-risk prostate cancer patients and assess its impact on dosimetry as well as acute toxicity. METHODS:A total of 70 patients treated with SBRT (total dose o...

journal_title：International journal of clinical oncology

authors： Kobayashi H,Eriguchi T,Tanaka T,Ogata T,Ishida M,Nakajima Y,Kumabe A,Kosugi M

更新日期：2021-01-07 00:00:00

abstract：BACKGROUND:Recurrent or persistent clear cell carcinoma (CCC) of the ovary is particularly chemotherapy resistant. The purpose of this study was to review our extensive institutional experiences with recurrent or persistent CCC with the aim of finding a more effective chemotherapy regimen. METHODS:The medical records ...

journal_title：International journal of clinical oncology

authors： Yoshino K,Enomoto T,Fujita M,Ueda Y,Kimura T,Kobayashi E,Tsutsui T,Kimura T

更新日期：2013-02-01 00:00:00

abstract：:The mechanisms and clinical significance of lymph node involvement in ovarian cancer have been revealed since the International Federation of Gynaecology and Obstetrics (FIGO) introduced a new clinical staging including retroperitoneal lymph node status. The multiple directions of the lymph drainage pathway in ovarian...

journal_title：International journal of clinical oncology

authors： Ushijima K

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND:This multi-center, phase III trial assesses the efficacy of daikenchuto (TU-100) on gastrointestinal disorders after hepatic resection (UMIN Registration No. 000003103). MATERIALS AND METHODS:A total of 231 patients, who underwent hepatic resection at 26 Japanese centers, were enrolled. Patients were random...

journal_title：International journal of clinical oncology

authors： Shimada M,Morine Y,Nagano H,Hatano E,Kaiho T,Miyazaki M,Kono T,Kamiyama T,Morita S,Sakamoto J,Kusano M,Saji S,Kanematsu T,Kitajima M

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:Detailed information is not currently available on the incidence, natural course, and management of asymptomatic abnormal prostate findings incidentally detected by radiologic evaluations after BCG therapy for non-muscle-invasive bladder cancer patients. METHODS:We identified 38 patients who were evaluated ...

journal_title：International journal of clinical oncology

authors： Matsushima M,Kikuchi E,Akita H,Miyajima A,Oya M,Jinzaki M

更新日期：2017-06-01 00:00:00

abstract：:We present the case of a 62-year-old Japanese man whose histological diagnosis was adenoendocrine cell carcinoma of the gallbladder at autopsy, but whose antemortem diagnosis was squamous cell carcinoma. The patient was admitted to hospital with complaints of occasional vomiting and abdominal pain. Abdominal computed ...

journal_title：International journal of clinical oncology

authors： Taniguchi H,Sakagami J,Suzuki N,Hasegawa H,Shinoda M,Tosa M,Baba T,Yasuda H,Kataoka K,Yoshikawa T

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:Trachelectomy was developed as a fertility-sparing surgery for early-stage cervical cancer in patients of childbearing age. The purpose of this study is to evaluate oncologic and obstetric outcomes and complications after abdominal trachelectomy. METHODS:We began to perform abdominal trachelectomy in 2005. ...

journal_title：International journal of clinical oncology

authors： Okugawa K,Kobayashi H,Sonoda K,Kaneki E,Kawano Y,Hidaka N,Egashira K,Fujita Y,Yahata H,Kato K

更新日期：2017-04-01 00:00:00

abstract：:A case of mantle cell lymphoma (MCL) associated with multiple lymphomatous polyposis (MLP) is reported is a 62-year-old woman, with special reference to the patient's clinical features and response to treatment. There were multiple widespread polypoid lesions in the entire gastrointestinal tract, with ileocecal masses...

journal_title：International journal of clinical oncology

authors： Tsujimura H,Takagi T,Tamaru J,Sakai C

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND:Although regorafenib or trifluridine/tipiracil (FTD/TPI) has been recognized as a later-line standard treatment in patients with metastatic colorectal cancer (mCRC), not all patients have beneficial outcomes. This study aimed to develop a prognostic scoring system for evaluating the overall survival (OS) ben...

journal_title：International journal of clinical oncology

authors： Moriwaki T,Fukuoka S,Masuishi T,Takashima A,Kumekawa Y,Kajiwara T,Yamazaki K,Esaki T,Makiyama A,Denda T,Hatachi Y,Suto T,Sugimoto N,Enomoto M,Ishikawa T,Kashiwada T,Oki E,Komatsu Y,Tsuji A,Tsuchihashi K,Sakai D,

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Neoplastic cardiac tamponade (NCT) is a life-threatening complication of cancer. The interval between cancer diagnosis and NCT onset and the prognosis after pericardiocentesis may differ according to cancer type. METHODS AND RESULTS:We performed a retrospective study of 113 patients (54 % male) with NCT who...

journal_title：International journal of clinical oncology

authors： Takayama T,Okura Y,Okada Y,Honma K,Nashimoto A,Sato N,Yokoyama A,Minamino T

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:We conducted a study to validate the influence of the systemic immune-inflammation index (SII) on overall survival (OS) in patients with metastatic renal cell carcinoma (mRCC) and to verify whether the implementation of the SII in place of neutrophil and platelet counts within the International Metastatic Re...

journal_title：International journal of clinical oncology

authors： Chrom P,Zolnierek J,Bodnar L,Stec R,Szczylik C

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:Set-up errors represent a source of uncertainty in head and neck (H&N) cancer radiotherapy. The present study evaluated set-up accuracy with the use of cone-beam computed tomography (CBCT) in order to establish the proper clinical target volume (CTV) to planning target volume (PTV) margins to be adopted. ME...

journal_title：International journal of clinical oncology

authors： Dionisi F,Palazzi MF,Bracco F,Brambilla MG,Carbonini C,Asnaghi DD,Monti AF,Torresin A

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Panitumumab is a fully human, monoclonal antibody against the epidermal growth factor receptor. Previous studies in non-Japanese patients with solid tumors showed that panitumumab exhibited nonlinear pharmacokinetics, was well tolerated (skin toxicities were the most common treatment-related adverse events),...

journal_title：International journal of clinical oncology

authors： Doi T,Ohtsu A,Tahara M,Tamura T,Shirao K,Yamada Y,Otani S,Yang BB,Ohkura M,Ohtsu T

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:The efficacy of individual chemotherapy based on chemosensitivity has scarcely been studied. METHODS:We examined the chemosensitivites for four anticancer agents - 1-(4-amino-2-methyl-5-pyrimidinyl) methyl-3 (2-chloroethyl)-3-nitrosourea hydrochloride (ACNU), carboplatin, cisplatin, and etoposide - of 43 ma...

journal_title：International journal of clinical oncology

authors： Ono A,Kanno H,Hayashi A,Nishimura S,Kyuma Y,Sato H,Ito S,Shimizu N,Chang CC,Gondo G,Yamamoto I,Sasaki T,Tanaka M

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:Soft-tissue tumors are often accompanied by abnormal temperature distribution detected during palpation. However, the assessment of temperature distribution is subjective, limiting its wide use in cancer screening. The aim of this study was to evaluate the clinical significance of the thermal detection of so...

journal_title：International journal of clinical oncology

authors： Shimatani A,Hoshi M,Oebisu N,Iwai T,Takada N,Nakamura H

更新日期：2020-07-01 00:00:00

abstract：:Prostate cancer is androgen-dependent, and hormone therapy, mainly achieved by androgen deprivation, has been one of the main treatment modalities in the clinical management of prostate cancer patients for more than six decades. In the 1980s, luteinizing hormone-releasing hormone agonists, which reduce testosterone to...

journal_title：International journal of clinical oncology

authors： Suzuki H,Kamiya N,Imamoto T,Kawamura K,Yano M,Takano M,Utsumi T,Naya Y,Ichikawa T

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:Liver resection is the most effective procedure for colorectal cancer liver metastasis (CRLM); however, early recurrence is an important problem that affects the postoperative prognoses of patients with CRLM. We previously suggested a therapeutic algorithm for CRLM using fluorodeoxyglucose-positron emission ...

journal_title：International journal of clinical oncology

authors： Watanabe A,Harimoto N,Yokobori T,Araki K,Kubo N,Igarashi T,Tsukagoshi M,Ishii N,Yamanaka T,Handa T,Oyama T,Higuchi T,Shirabe K

更新日期：2020-02-01 00:00:00

abstract：:Primary sarcoma of the fallopian tube is a very rare neoplasm. We report the case of a 69-year-old woman affected with leiomyosarcoma of the left fallopian tube. Her chief complaint was lower abdominal pain. The preoperative diagnosis was a left adnexal malignant tumor based on pelvic examination, abdominal computed t...

journal_title：International journal of clinical oncology

authors： Ueda T,Emoto M,Fukuoka M,Miyahara D,Horiuchi S,Tsujioka H,Kawarabayashi T

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:Phase I study of weekly administration of low-dose docetaxel/cisplatin concurrent with conventionally fractionated radiotherapy for locally advanced head and neck squamous cell carcinoma suggested the recommended dose of docetaxel at 10 mg/m2 and cisplatin at 20 mg/m2. Phase II study of the concurrent chemor...

journal_title：International journal of clinical oncology

authors： Nakahara S,Takenaka Y,Ogawa K,Nishiike S,Yamamoto Y,Seo Y,Isohashi F,Suzuki O,Yoshioka Y,Sumida I,Yoshii T,Tomiyama Y,Inohara H

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:To avoid the loss of fertility, chemotherapy should be chosen as an adjuvant treatment after trachelectomy. Our study evaluated the effectiveness and safety of adjuvant chemotherapy after abdominal trachelectomy for cervical cancer. METHODS:Our institutional review board approved this clinical study, and in...

journal_title：International journal of clinical oncology

authors： Okugawa K,Yahata H,Sonoda K,Kodama K,Yagi H,Ohgami T,Yasunaga M,Onoyama I,Kaneki E,Asanoma K,Kobayashi H,Kato K

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:As cancer therapy can be harmful to spermatogenesis, men are generally advised to cryopreserve sperm before gonadotoxic treatment. Here, we compared fresh and frozen-thawed sperm quality in patients according to cancer type, and reported use rate in subsequent assisted reproductive technology (ART) cycles. ...

journal_title：International journal of clinical oncology

authors： Freour T,Mirallie S,Jean M,Barriere P

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:The aim of this study was to investigate the screening rate for hepatitis B virus (HBV) infection, which is recommended by some guidelines for the prevention of HBV reactivation, in patients undergoing chemotherapy for malignancy in Japan. METHODS:The study subjects were 3302 patients who had received first...

journal_title：International journal of clinical oncology

authors： Ikeda M,Yamamoto H,Kaneko M,Oshima H,Takahashi H,Umemoto K,Watanabe K,Hashimoto Y,Ohno I,Mitsunaga S,Okusaka T

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Pulmonary metastasectomy in patients with renal cell carcinoma (RCC) remains controversial. The purpose of our analysis was to explore the outcome of patients with RCC who underwent pulmonary metastasectomy at our institution. METHODS:We reviewed data on 25 patients who underwent resection of lung metastasi...

journal_title：International journal of clinical oncology

authors： Kawashima A,Nakayama M,Oka D,Sato M,Hatano K,Mukai M,Nagahara A,Nakai Y,Takayama H,Inoue M,Shiono H,Nishimura K,Okumura M,Nonomura N

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:The present study investigated whether treatment with anginex, a novel antiangiogenic peptide, could block re-vascularization after radiation treatment. METHODS:A squamous cell (SCCVII) xenograft tumor mouse model was employed to assess the effects of anginex given post-radiation on tumor growth, microvesse...

journal_title：International journal of clinical oncology

authors： Amano M,Suzuki M,Andoh S,Monzen H,Terai K,Williams B,Song CW,Mayo KH,Hasegawa T,Dings RP,Griffin RJ

更新日期：2007-02-01 00:00:00