Fucoidan, a sulfated polysaccharide from brown algae, improves cognitive impairment induced by infusion of Aβ peptide in rats.

abstract：:The cytochrome P450 enzyme 2E1 (CYP2E1) presents in both microsome and mitochondrion, which influences the metabolism of many xenobiotics. The mice active liver homogenate was prepared for the medicinal incubation and mitochondrion was extracted for chemical screening targeting CYP2E1 enzyme. Representative CYP2E1 ind...

journal_title：Environmental toxicology and pharmacology

authors： Wang M,Zhou Z,Wang J,Zhang X

更新日期：2016-10-01 00:00:00

abstract：:The Opuntia ficus indica f. inermis methanolic flowers extract (OMFE) was phytochemical studied, in vitro tested for their potential antioxidant activity using 2,2-diphenyl-1-picrylhydrazyl (DPPH), reducing power, linoleic acid peroxidation assays and in vivo evaluated for its ability to prevent ethanol-induced gastri...

journal_title：Environmental toxicology and pharmacology

authors： Alimi H,Hfaiedh N,Bouoni Z,Sakly M,Ben Rhouma K

更新日期：2011-11-01 00:00:00

abstract：:Essential oils from aerial parts of Piper aduncum (Matico) and Piper obliquum (Anis del Oriente) of ecuadorian origin were analyzed by GC-FID, GC-MS, (13)C NMR and their biological and pharmacological activities were assessed. Chemical composition proved to be unusually different from previous reports for safrole-rich...

journal_title：Environmental toxicology and pharmacology

authors： Guerrini A,Sacchetti G,Rossi D,Paganetto G,Muzzoli M,Andreotti E,Tognolini M,Maldonado ME,Bruni R

更新日期：2009-01-01 00:00:00

abstract：:The study investigated the correlation between infarction areas and behavioural deficits in middle cerebral artery occlusion (MCAO) and photothrombosis stroke models. In the MCAO model, a 0.38 mm-diameter silicone-coated thread was introduced through the left external carotid artery and advanced 18 mm via the internal...

journal_title：Environmental toxicology and pharmacology

authors： Choi BI,Park D,Lee SH,Bae DK,Yang G,Yang YH,Kim TK,Choi EK,Lee HJ,Choi KC,Nahm SS,Kim YB

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Sulfur mustard is an alkylating agent which cause to short and long term incapacitations on various organs including lung. There is no definite treatment for lung disorders induced by SM exposure. In the present study, the preventive effect of Zataria multiflora (Z. multiflora) on hematological parameters, o...

journal_title：Environmental toxicology and pharmacology

authors： Khazdair MR,Rajabi O,Balali-Mood M,Beheshti F,Boskabady MH

更新日期：2018-03-01 00:00:00

abstract：:Earthworms are the key soil organisms, contribute to many positive ecological services that could be degraded by pesticides and other soil pollutants such as heavy metals. Chemicals usually occur as mixtures in the environmental systems which can lead synergistic effects. The assessment and characterization of soil po...

journal_title：Environmental toxicology and pharmacology

authors： Uwizeyimana H,Wang M,Chen W,Khan K

更新日期：2017-10-01 00:00:00

abstract：:The dechlorination of PCB, specifically the noncoplanar congener PCB 153, has been observed in the presence of a crude nitrate reductase extract from Medicago sativa leaves. These observations were further confirmed using a commercially available and pure nitrate reductase from Zea mays. The presence of nitrate reduct...

journal_title：Environmental toxicology and pharmacology

authors： Magee KD,Michael A,Ullah H,Dutta SK

更新日期：2008-03-01 00:00:00

abstract：:Serious bacterial pathogens have recently become a major cause of massive mortality in swimming crabs (Portunus trituberculatus). In this study, the antibacterial activity against Vibrio and the pharmacokinetics (PK) of sulfamethoxazole (SMZ)-trimethoprim (TMP) in crabs were estimated to explore the pharmacokinetics/p...

journal_title：Environmental toxicology and pharmacology

authors： Fu G,Peng J,Wang Y,Zhao S,Fang W,Hu K,Shen J,Yao J

更新日期：2016-09-01 00:00:00

abstract：:Air pollution is a topic discussed all over the world and the search for alternatives to reduce it is of great interest to many researchers. The use of alternative energy sources and biofuels seems to be the environmentally safer solution. In this work, the deleterious effects on the respiratory system of mice exposed...

journal_title：Environmental toxicology and pharmacology

authors： Josino JB,Serra DS,Gomes MDM,Araújo RS,de Oliveira MLM,Cavalcante FSÁ

更新日期：2017-12-01 00:00:00

abstract：:This study examines strain differences in testosterone (T)-hydroxylations between Wistar and Dark Agouti (DA) rats of both genders. The DA rat, an animal model, is a poor metabolizer of such drugs as debrisoquine, which are metabolized by cytochrome P450 (CYP) 2D. T-16α-, 2α-hydroxylations, which are linked to CYP2C11...

journal_title：Environmental toxicology and pharmacology

authors： Maeda Y,Morita K,Tasaki T,Kazusaka A,Imaoka S,Funae Y,Fujita S

更新日期：1997-02-15 00:00:00

abstract：:Cleft palate(CP) is a widely studied congenital malformation. However, its etiology and pathogenesis still remain unclear. Proteins are fundamental molecules that participate in every biological process within cells. In this study, we established CP mouse models induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) an...

journal_title：Environmental toxicology and pharmacology

authors： Wang C,Zhai SN,Yuan XG,Zhang DW,Jiang H,Qiu L,Fu YX

更新日期：2019-11-01 00:00:00

abstract：:Safrole is a natural compound categorized as a group 2B carcinogen extracted from betel quid chewing, which is a common practice of psychoactive habits integrated into social and cultural ceremonies among serveral million people, especially in Southern or Southeastern Asia. Safrole is one of the major risk compunds fo...

journal_title：Environmental toxicology and pharmacology

authors： Chien KJ,Yang ML,Tsai PK,Su CH,Chen CH,Horng CT,Yeh CH,Chen WY,Lin ML,Chen CJ,Chian CY,Kuan YH

更新日期：2018-12-01 00:00:00

abstract：:Cadmium (Cd), an environmental and industrial pollutant, generates free radicals responsible for oxidative stress. Cd can also lead to various renal toxic damage such as the proximal tubules and glomerulus dysfunction. Plantamajoside (PMS), a major compound of Plantago asiatica (PA), was reported to have the antioxida...

journal_title：Environmental toxicology and pharmacology

authors： Jung HY,Seo DW,Hong CO,Kim JY,Yang SY,Lee KW

更新日期：2015-01-01 00:00:00

abstract：:Application of human antidotes against nerve agent intoxications to microcrustacean Daphnia magna (Crustacea, Cladocera) intoxicated by a nerve agent tabun (O-ethyl-N,N-dimethylphosphoramidocyanidate) and their efficacy was investigated. It was found that antidotes can be successfully applied to intoxicated daphnids. ...

journal_title：Environmental toxicology and pharmacology

authors： Vesela S,Kuca K,Jun D

更新日期：2008-05-01 00:00:00

abstract：:In this study, the hepatoprotective effect of dieckol on carbon tetrachloride (CCl4) induced hepatic damages in ICR mice liver was investigated. Mice were randomly divided into 4 groups such as saline treated (negative control), CCl4 treated (positive control), CCl4+dieckol (5mg/kg mouse) and CCl4+dieckol (25mg/kg mou...

journal_title：Environmental toxicology and pharmacology

authors： Kang MC,Kang SM,Ahn G,Kim KN,Kang N,Samarakoon KW,Oh MC,Lee JS,Jeon YJ

更新日期：2013-05-01 00:00:00

abstract：:The molecular and histological effects of tumor promoters on gap junctional intercellular communication (GJIC) were studied in three mouse epidermal cell types, representing different stages of tumor formation. GJIC was inhibited by most of the studied compounds (l-ethionine, d-limonene, o-anisidine, clofibrate, Arocl...

journal_title：Environmental toxicology and pharmacology

authors： Jansen L,Mesnil M,Koeman J,Jongen W

更新日期：1996-05-15 00:00:00

abstract：:Quantitative structure - activity relationships (QSARs) which are obtained with a representation of the molecular architecture via simplified molecular input-line entry system (SMILES) are applied to build up predictive models of acute toxicity of pesticides towards Daphnia magna. The acute toxicity towards Daphnia ma...

journal_title：Environmental toxicology and pharmacology

authors： Cappelli CI,Toropov AA,Toropova AP,Benfenati E

更新日期：2020-11-01 00:00:00

abstract：:The aim of this study was to investigate the effect of betaine (BET) on alcoholic liver fibrosis in rats. Fibrosis was experimentally generated with ethanol plus carbon tetrachloride (ETH+CCl4) treatment. Rats were treated with ETH (5% v/v in drinking water) for 14 weeks. CCl4 was administered intraperitoneally (i.p.)...

journal_title：Environmental toxicology and pharmacology

authors： Bingül İ,Başaran-Küçükgergin C,Aydın AF,Çoban J,Doğan-Ekici I,Doğru-Abbasoğlu S,Uysal M

更新日期：2016-07-01 00:00:00

abstract：:To investigate the regulated role of IL-1β in initiating and maintaining inflammation, PMA-differentiated THP-1 macrophages were exposed to two micro-sized crystalline silica particles (Si3-5μm and Si1μm) from 3h to 24h, respectively. Cytotoxicity and inflammatory cytokines (IL-1β, TNF-α and IL-6) expressions measured...

journal_title：Environmental toxicology and pharmacology

authors： Zhou T,Cui X,Zhou Y,Guo J,Rong Y,Chen W

更新日期：2015-01-01 00:00:00

abstract：:Changes in some blood parameters after 12-week administration of sodium metavanadate (SMV; 0.125mgV/ml) or/and magnesium sulphate (MS; 0.06mgMg/ml) in drinking water were studied in outbred male Wistar rats (16 rats/each group) to explore the probable mechanism(s) underlying SMV toxicity and check whether Mg at the le...

journal_title：Environmental toxicology and pharmacology

authors： Ścibior A,Adamczyk A,Gołębiowska D,Niedźwiecka I

更新日期：2012-09-01 00:00:00

abstract：:We previously observed that nonylphenol (NP) exposure during development resulted in increases in body weight and hyperadrenalism in adult male offspring. The mechanism of hyperadrenalism includes the primary activation of the adrenal gland and the conversion of inactive glucocorticoids to active glucocorticoids by 11...

journal_title：Environmental toxicology and pharmacology

authors： Chang LL,Wun WS,Wang PS

更新日期：2016-06-01 00:00:00

abstract：:We investigated the effect of phytosterol (PS) in regard to liver damage induced by 4-nitrophenol (PNP). Twenty rats were randomly divided into four groups (Control, PS, PNP, and PNP+PS). The PS and PNP+PS groups were pretreated with PS for one week. The PNP and PNP+PS groups were injected subcutaneously with PNP for ...

journal_title：Environmental toxicology and pharmacology

authors： Chen J,Song M,Li Y,Zhang Y,Taya K,Li C

更新日期：2016-01-01 00:00:00

abstract：:The Tokyo subway sarin attack was the second documented incident of nerve gas poisoning in Japan. The St. Luke's International Hospital received 640 patients on the day of the attack. Reduction in plasma cholinesterase (ChE) activity was generally associated with the severity of acute signs of toxicity. With time and ...

journal_title：Environmental toxicology and pharmacology

authors： Okumura T,Hisaoka T,Naito T,Isonuma H,Okumura S,Miura K,Maekawa H,Ishimatsu S,Takasu N,Suzuki K

更新日期：2005-05-01 00:00:00

abstract：:Crops produced through genetic modification are beginning to reach the market and many genetically-modified crops are under development. Since genetic modification results in the introduction of new proteins into the food plant the safety of the newly introduced proteins must be assessed. The potential allergenicity o...

journal_title：Environmental toxicology and pharmacology

authors： Taylor SL

更新日期：1997-11-01 00:00:00

abstract：:Pimpinella brachycarpa (Kom.) Nakai (PB) is one of the most favored edible greens grown in Asian regions. In our previously study, we found PB extract had antioxidant effects in vitro. In the present study, an EtOAc soluble extract (PBet) was isolated from PB. Then the antioxidant properties at cellular level, phytoch...

journal_title：Environmental toxicology and pharmacology

authors： Lu J,Qian W,Xu L,Huang G,Cong W,Wang Z,Deng X,Wang D,Guan S

更新日期：2012-09-01 00:00:00

abstract：:The environmental pollutant bisphenol A dimethacylate (BAD) has been used as a dental composite. The effect of BAD on cytosolic Ca(2+) concentrations ([Ca(2+)]i) and viability in OC2 human oral cancer cells was explored. The Ca(2+)-sensitive fluorescent dye fura-2 was applied to measure [Ca(2+)]i. BAD induced [Ca(2+)]...

journal_title：Environmental toxicology and pharmacology

authors： Chien JM,Chou CT,Lu YC,Lu T,Chi CC,Tseng LL,Liu SI,Cheng JS,Kuo CC,Liang WZ,Jan CR

更新日期：2013-03-01 00:00:00

abstract：:Susceptibility is well-recognized as a potentially important aspect of health risk assessment, particularly for groups such as pregnant women and their fetuses, infants, children, the elderly, and the infirm, that are known or suspected to be more vulnerable to environmental insults. More recently, it has become appar...

journal_title：Environmental toxicology and pharmacology

authors： Sexton K

更新日期：1997-12-01 00:00:00

abstract：:Palladium (Pd) is known to be released into the environment in the fine and ultrafine (at the nanoscale) airborne particle fractions mainly from automobile catalytic converters leading to an increase human exposure to this noble metal. It was reported that Pd can induce allergic reactions in individuals exposed to it ...

journal_title：Environmental toxicology and pharmacology

authors： Chhay P,Murphy-Marion M,Samson Y,Girard D

更新日期：2018-01-01 00:00:00

abstract：:4-tert-octylphenol (4t-OP) is a well-known xenoestrogen. Our objective was to explore the effects and molecular mechanisms of 4t-OP on human sperm. Sperm samples were exposed to 0, 0.1, or 0.3 mM 4t-OP for two hours. Results showed that both sperm viability and motility were significantly injured by 0.3 mM 4t-OP. We a...

journal_title：Environmental toxicology and pharmacology

authors： Huang S,Cao S,Zhou T,Kong L,Liang G

更新日期：2018-09-01 00:00:00

abstract：:Chromium (Cr) (VI) compounds are known carcinogens and mutagens. The mechanism of carcinogenicity and mutagenicity caused by chromium(VI) compounds remained unclear for several years. However, in the recent past chromium-induced carcinogenicity and/or mutagenicity was known to happen due to the generation of reactive ...

journal_title：Environmental toxicology and pharmacology

authors： Acharya UR,Mishra M,Mishra I,Tripathy RR

更新日期：2004-01-01 00:00:00