当前位置： SCI文献检索 > ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY期刊下所有文献 > Acute and chronic effects of sarin exposure from the Tokyo subway incident.

Acute and chronic effects of sarin exposure from the Tokyo subway incident.

Abstract：

:The Tokyo subway sarin attack was the second documented incident of nerve gas poisoning in Japan. The St. Luke's International Hospital received 640 patients on the day of the attack. Reduction in plasma cholinesterase (ChE) activity was generally associated with the severity of acute signs of toxicity. With time and treatment, the value rose quickly. To evaluate possible residual signs of symptoms 1 year after the attack, we sent questionnaires to the victims; of 303 respondents, 45% still had some symptoms including eye problems, easy fatigability, headache, and fear. Therefore, we conducted a study in collaboration with investigators at the Tokyo University Department of Public Health to evaluate possible long-term neuropsychological sequelae. The findings suggest the need to closely follow such patients for possible persistent functional changes.

journal_name

Environ Toxicol Pharmacol

journal_title

Environmental toxicology and pharmacology

authors

Okumura T,Hisaoka T,Naito T,Isonuma H,Okumura S,Miura K,Maekawa H,Ishimatsu S,Takasu N,Suzuki K

doi

10.1016/j.etap.2004.12.005

subject

Has Abstract

pub_date

2005-05-01 00:00:00

pages

447-50

issue

3

eissn

1382-6689

issn

1872-7077

pii

S1382-6689(04)00266-2

journal_volume

19

pub_type

杂志文章

相关文献

ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY文献大全
  • Dechlorination of PCB in the presence of plant nitrate reductase.

    abstract：:The dechlorination of PCB, specifically the noncoplanar congener PCB 153, has been observed in the presence of a crude nitrate reductase extract from Medicago sativa leaves. These observations were further confirmed using a commercially available and pure nitrate reductase from Zea mays. The presence of nitrate reduct...

    journal_title：Environmental toxicology and pharmacology

    pub_type： 杂志文章

    doi：10.1016/j.etap.2007.10.009

    authors： Magee KD,Michael A,Ullah H,Dutta SK

    更新日期：2008-03-01 00:00:00

  • In situ assessment of Karaj River genotoxic impact with the alkaline comet assay and micronucleus test, on feral brown trout (Salmo trutta fario).

    abstract：:The in situ evaluation of the genotoxic impact of the Karaj River was performed using the comet and micronucleus (MN) assays in erythrocytes, liver, gill and kidney of indigenous brown trout, Salmo trutta fario from three different stations, including Varangerud, Asara and Purkan. The results showed that DNA damage si...

    journal_title：Environmental toxicology and pharmacology

    pub_type： 杂志文章

    doi：10.1016/j.etap.2017.12.024

    authors： Hariri M,Mirvaghefi A,Farahmand H,Taghavi L,Shahabinia AR

    更新日期：2018-03-01 00:00:00

  • Pesticides and their binary combinations as P-glycoprotein inhibitors in NIH 3T3/MDR1 cells.

    abstract：:The purpose of the present study was to assess do selected pesticides as well as their binary combinations act as inhibitors of P-glycoprotein (P-gp) activity of NIH 3T3 mouse fibroblasts stably transfected with human MDR1 gene (NIH 3T3/MDR1). As a result of P-gp inhibition, the increase of intracellular accumulation ...

    journal_title：Environmental toxicology and pharmacology

    pub_type： 杂志文章

    doi：10.1016/j.etap.2006.04.002

    authors： Pivčević B,Zaja R

    更新日期：2006-11-01 00:00:00

  • Mechanism based QSAR studies of N-phenylbenzamides as antimicrobial agents.

    abstract：:N-Phenyl benzamides are potent antibacterial agents. They are active against both Gram-positive and Gram-negative bacteria. The Gram-positive bacteria have strong and thick cell wall while the Gram-negative bacterial have thin and permeable cell wall. The DFT based QSAR reveals that molecular weight and total energy s...

    journal_title：Environmental toxicology and pharmacology

    pub_type： 杂志文章

    doi：10.1016/j.etap.2008.01.005

    authors： Pasha FA,Muddassar M,Lee C,Cho SJ

    更新日期：2008-09-01 00:00:00

  • Blood selenium concentration in a selected population of children inhabiting industrial regions in Upper Silesia (Poland).

    abstract：PURPOSE:Present study aimed at determining blood selenium concentration (Se-B) in a selected population of children inhabiting industrial regions. METHODS:The studies were conducted on a group of 267 children inhabiting industrial regions in Upper Silesia (Poland). Determination of Se-B was performed using hydride gen...

    journal_title：Environmental toxicology and pharmacology

    pub_type： 杂志文章

    doi：10.1016/j.etap.2012.06.005

    authors： Gać P,Pawlas N,Poręba R,Poręba M,Prokopowicz A,Pawlas K

    更新日期：2012-09-01 00:00:00

  • In vitro myelotoxicity of environmental contaminants.

    abstract：:Myelotoxicity of pesticides and algal toxins was detected in vitro by using the granulocyte-macrophage colony forming unit assay (CFU-GM), and the MTT test with SR-4987 cells, an established stromal cell line derived from a long term murine bone marrow culture, which may represent a suitable in vitro model for studyin...

    journal_title：Environmental toxicology and pharmacology

    pub_type： 杂志文章

    doi：10.1016/s1382-6689(98)00029-5

    authors： Gribaldo L,Casati S,Figliuzzi L,Marafante E

    更新日期：1998-10-01 00:00:00

  • Assessment of multipathway exposure of small children to PAH.

    abstract：:The aim of study was to assess the uptake of polycyclic aromatic hydrocarbons (PAH) by children living in a city and its effect on 1-hydroxypyrene (1-OHP) excretion. Two groups of children (n=11 and 13; 3-6 years old) were chosen: (1) a group from a kindergarten situated near a road with a high traffic density ('pollu...

    journal_title：Environmental toxicology and pharmacology

    pub_type： 杂志文章

    doi：10.1016/s1382-6689(00)00032-6

    authors： Vyskocil A,Fiala Z,Chénier V V,Krajak L,Ettlerova E,Bukac J,Viau C,Emminger S

    更新日期：2000-01-01 00:00:00

  • Impact of long term Fe³⁺ toxicity on expression of glutathione system in rat liver.

    abstract：:The free radicals within the body, produced by metabolic activities or derived from environmental sources are relatively related to hepatoxicity. Since heavy metals including iron have the ability to produce free radicals, the liver glutathione system neutralizes them to protect cells against any damage. The objective...

    journal_title：Environmental toxicology and pharmacology

    pub_type： 杂志文章

    doi：10.1016/j.etap.2013.12.007

    authors： Budak H,Gonul N,Ceylan H,Kocpinar EF

    更新日期：2014-01-01 00:00:00

  • GS-2, a pyrazolo[1,5-a]indole derivative with inhibitory activity of topoisomerases, exerts its potent cytotoxic activity by ROS generation.

    abstract：:Pyrazolo[1,5-a]indole derivatives, a new type of topoisomerase (topo) inhibitor, demonstrate a broad spectrum of antitumor activities. However, the mechanism underlying the induced cytotoxicity remains unclear. In this study, we investigated whether GS-2, one of the derivatives, altered the levels of ROS in breast can...

    journal_title：Environmental toxicology and pharmacology

    pub_type： 杂志文章

    doi：10.1016/j.etap.2013.09.019

    authors： Ji YY,Zhu YM,Wang JW

    更新日期：2013-11-01 00:00:00

  • Bisphenol A and its analogs: Do their metabolites have endocrine activity?

    abstract：:Structural analogs of bisphenol A are commonly used as its alternatives in industrial and commercial applications. Nevertheless, the question arises whether the use of other bisphenols is justified as replacements for bisphenol A in mass production of plastic materials. To evaluate the influence of metabolic reactions...

    journal_title：Environmental toxicology and pharmacology

    pub_type： 杂志文章,评审

    doi：10.1016/j.etap.2016.09.014

    authors： Gramec Skledar D,Peterlin Mašič L

    更新日期：2016-10-01 00:00:00

  • Environmental epigenomics: Current approaches to assess epigenetic effects of endocrine disrupting compounds (EDC's) on human health.

    abstract：:Environmental Epigenomics is a developing field to study the epigenetic effect on human health from exposure to environmental factors. Endocrine disrupting chemicals have been detected primarily in pharmaceutical drugs, personal care products, food additives, and food containers. Exposure to endocrine-disrupting chemi...

    journal_title：Environmental toxicology and pharmacology

    pub_type： 杂志文章,评审

    doi：10.1016/j.etap.2017.02.004

    authors： Tapia-Orozco N,Santiago-Toledo G,Barrón V,Espinosa-García AM,García-García JA,García-Arrazola R

    更新日期：2017-04-01 00:00:00

  • Potential role of vitamins in chromium induced spermatogenesis in Swiss mice.

    abstract：:Chromium (Cr) (VI) compounds are known carcinogens and mutagens. The mechanism of carcinogenicity and mutagenicity caused by chromium(VI) compounds remained unclear for several years. However, in the recent past chromium-induced carcinogenicity and/or mutagenicity was known to happen due to the generation of reactive ...

    journal_title：Environmental toxicology and pharmacology

    pub_type： 杂志文章

    doi：10.1016/j.etap.2003.08.010

    authors： Acharya UR,Mishra M,Mishra I,Tripathy RR

    更新日期：2004-01-01 00:00:00

  • The interplay of the inhibitory effect of nifuroxazide on NF-κB/STAT3 signaling attenuates acetic acid-induced ulcerative colitis in rats.

    abstract：:Ulcerative colitis (UC) is a disease of increased worldwide prevalence. UC progression is associated with serious complications that leave the patient with considerable health burdens. Nifuroxazide is an oral nitrofuran antibiotic used as antidiarrheal medication. The current study places an emphasis on investigating ...

    journal_title：Environmental toxicology and pharmacology

    pub_type： 杂志文章

    doi：10.1016/j.etap.2020.103433

    authors： El-Far YM,Elsherbiny NM,El-Shafey M,Said E

    更新日期：2020-10-01 00:00:00

  • Effects of cigarette smoke on Holter ECG recordings in patients with arterial hypertension. Part 2: Parameters of heart rate turbulence.

    abstract：UNLABELLED:The studies aimed at evaluation of cigarette smoke effect on heart rate turbulence (HRT) in patients with arterial hypertension (AH). 223 consecutive individuals were qualified to the studies. The following groups of patients not suffering from other disease which may affect HRT were distinguished: 1--patien...

    journal_title：Environmental toxicology and pharmacology

    pub_type： 杂志文章

    doi：10.1016/j.etap.2014.01.022

    authors： Gać P,Sobieszczańska M

    更新日期：2014-03-01 00:00:00

  • DNA damaging and apoptotic potentials of Bisphenol A and Bisphenol S in human bronchial epithelial cells.

    abstract：:DNA damage caused by environmental agents often lead to many chronic diseases, including cancer. The present study aimed to understand the relative toxicity possessed by Bisphenol A (BPA) and Bisphenol S (BPS) on human bronchial epithelial cells (BEAS-2B). The cells were exposed to either BPA or BPS and evaluated for ...

    journal_title：Environmental toxicology and pharmacology

    pub_type： 杂志文章

    doi：10.1016/j.etap.2018.04.009

    authors： George VC,Rupasinghe HPV

    更新日期：2018-06-01 00:00:00

  • Ecotoxicity of veterinary enrofloxacin and ciprofloxacin antibiotics on anuran amphibian larvae.

    abstract：:The ecological risks posed by two β-diketone antibiotics (DKAs, enrofloxacin, ENR and ciprofloxacin, CPX), characterized by their long persistence in aqueous environments and known deleterious effect on model organisms such as zebrafish were analysed using Rhinella arenarum larvae. Sublethal tests were conducted using...

    journal_title：Environmental toxicology and pharmacology

    pub_type： 杂志文章

    doi：10.1016/j.etap.2017.01.021

    authors： Peltzer PM,Lajmanovich RC,Attademo AM,Junges CM,Teglia CM,Martinuzzi C,Curi L,Culzoni MJ,Goicoechea HC

    更新日期：2017-04-01 00:00:00

  • Genistein ameliorated endothelial nitric oxidase synthase uncoupling by stimulating sirtuin-1 pathway in ox-LDL-injured HUVECs.

    abstract：:Endothelial nitric oxidase synthase (eNOS) uncoupling plays a causal role in endothelial dysfunction in atherosclerosis. Genistein consumption has been associated with the prevention of atherosclerosis. However, the effect of genistein on eNOS uncoupling has not been reported. A model of oxidized low-density lipoprote...

    journal_title：Environmental toxicology and pharmacology

    pub_type： 杂志文章

    doi：10.1016/j.etap.2016.01.011

    authors： Zhang HP,Zhao JH,Yu HX,Guo DX

    更新日期：2016-03-01 00:00:00

  • Identification of estrogenic activity of chlorinated bisphenol A using a GFP expression system.

    abstract：:A green fluorescent protein (GFP)-reporter vector regulated by an estrogen response element (ERE) was constructed and transfected into human breast carcinoma MCF7 cells. Stable transfectants were selected and their GFP fluorescence intensity was measured using a quantitative fluorescent imaging system. 17β-estradiol (...

    journal_title：Environmental toxicology and pharmacology

    pub_type： 杂志文章

    doi：10.1016/s1382-6689(02)00011-x

    authors： Kuruto-Niwa R,Terao Y,Nozawa R

    更新日期：2002-08-01 00:00:00

  • Pharmacologically prospective antibiotic agents and their sources: a marine microbial perspective.

    abstract：:Marine microbes have been a storehouse of bioactive metabolites with tremendous potential as drug candidates. Marine microorganism derived secondary metabolites (chemical compounds/peptides) are considered to be a burning area of research since recent past. Many of such compounds have been proven to be anti-bacterial,...

    journal_title：Environmental toxicology and pharmacology

    pub_type： 杂志文章,评审

    doi：10.1016/j.etap.2012.08.016

    authors： Bhatnagar I,Kim SK

    更新日期：2012-11-01 00:00:00

  • A new index to assess chemicals increasing the greenhouse effect based on their toxicity to algae.

    abstract：:CO2, as the typical greenhouse gas causing the greenhouse effect, is a major global environmental problem and has attracted increasing attention from governments. Using algae to eliminate CO2, which has been proposed as an effective way to reduce the greenhouse effect in the past decades, can be disturbed by a growing...

    journal_title：Environmental toxicology and pharmacology

    pub_type： 杂志文章

    doi：10.1016/j.etap.2015.08.034

    authors： Wang T,Zhang X,Tian D,Gao Y,Lin Z,Liu Y,Kong L

    更新日期：2015-11-01 00:00:00

  • The protective role of vitamin E on gill and liver tissue histopathology and micronucleus frequencies in peripheral erythrocytes of Oreochromis niloticus exposed to deltamethrin.

    abstract：:Deltamethrin, is a commonly used pyrethroid pesticide. Vitamin E is a antioxidant that plays an important role in protecting cells against toxicity by inactivating free radicals generated following pesticides exposure. Therefore, it was evaluated whether deltamethrin induced histopathological changes and nuclear abnor...

    journal_title：Environmental toxicology and pharmacology

    pub_type： 杂志文章

    doi：10.1016/j.etap.2012.03.009

    authors： Kan Y,Cengiz EI,Ugurlu P,Yanar M

    更新日期：2012-09-01 00:00:00

  • Differences in binding of epidermal growth factor to liver membranes of TCDD-resistant and TCDD-sensitive rats after a single dose of TCDD.

    abstract：:Epidermal growth factor (EGF) receptor has been implied as having a role in certain actions of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). After a single dose of TCDD, the receptor has been shown to be downregulated in several tissues including the liver. Two rat substrains, the Han/Wistar (Kuopio; H/W) rat and the Lo...

    journal_title：Environmental toxicology and pharmacology

    pub_type： 杂志文章

    doi：10.1016/1382-6689(95)00016-x

    authors： Tuomisto J,Sewall CH,Unkila M,Pohjanvirta R,Clark GC,Viluksela M,Rozman K,Lucier GW

    更新日期：1996-04-15 00:00:00

  • Natural and synthetic organic compounds in the environment-a symposium report.

    abstract：:In March 2000, an international two-day symposium was organized in Noordwijkerhout, The Netherlands, on 'Natural and synthetic organic compounds in the environment'. The emphasis of the symposium was on the following classes of compounds: polycyclic aromatic hydrocarbons, xeno-estrogens, phyto-estrogens, and veterinar...

    journal_title：Environmental toxicology and pharmacology

    pub_type： 杂志文章

    doi：10.1016/s1382-6689(01)00090-4

    authors： Ariese F,Ernst WH,Sijm DT

    更新日期：2001-07-01 00:00:00

  • Ardipusilloside I induces apoptosis in human glioblastoma cells through a caspase-8-independent FasL/Fas-signaling pathway.

    abstract：:Ardipusilloside I, a triterpenoid saponin isolated from Ardisia pusilla A. DC, suppresses the growth of a variety of cancer cells, and has certain immunomodulative properties. Herein, we investigated its effect on glioblastoma cell line U87MG cells and primary cultured human glioblastoma cells, and examined the underl...

    journal_title：Environmental toxicology and pharmacology

    pub_type： 杂志文章

    doi：10.1016/j.etap.2008.11.008

    authors： Xiong J,Cheng G,Tang H,Zhen HN,Zhang X

    更新日期：2009-03-01 00:00:00

  • The effect of phytosterol protects rats against 4-nitrophenol-induced liver damage.

    abstract：:We investigated the effect of phytosterol (PS) in regard to liver damage induced by 4-nitrophenol (PNP). Twenty rats were randomly divided into four groups (Control, PS, PNP, and PNP+PS). The PS and PNP+PS groups were pretreated with PS for one week. The PNP and PNP+PS groups were injected subcutaneously with PNP for ...

    journal_title：Environmental toxicology and pharmacology

    pub_type： 杂志文章

    doi：10.1016/j.etap.2015.12.011

    authors： Chen J,Song M,Li Y,Zhang Y,Taya K,Li C

    更新日期：2016-01-01 00:00:00

  • Therapeutic potential of thymoquinone against anti-tuberculosis drugs induced liver damage.

    abstract：:Hepatotoxicity is the most serious adverse effect related to tuberculosis treatment which interrupts the successful completion of tuberculosis treatment. The purpose of this study was to assess therapeutic effect of thymoquinone (TQ) against anti-tuberculosis drugs (ATD) induced liver damage. Rats were treated with AT...

    journal_title：Environmental toxicology and pharmacology

    pub_type： 杂志文章

    doi：10.1016/j.etap.2013.07.010

    authors： Jaswal A,Sinha N,Bhadauria M,Shrivastava S,Shukla S

    更新日期：2013-11-01 00:00:00

  • Pharmacokinetic profile of cefquinome after oral subchronic flubendiamide exposure and in vitro plasma protein binding in buffalo calves.

    abstract：:The disposition kinetics study of cefquinome was conducted following single intravenous (IV) administration of 2mg/kg bodyweight in buffalo calves after oral subchronic exposure to flubendiamide and to determine the in vitro plasma protein binding of cefquinome. Plasma concentrations of cefquinome were analyzed using ...

    journal_title：Environmental toxicology and pharmacology

    pub_type： 杂志文章

    doi：10.1016/j.etap.2014.12.004

    authors： Venkatachalam D,Dumka VK

    更新日期：2015-01-01 00:00:00

  • Purification and characterization of antioxidant components from the fruiting bodies of Pleurotus abalonus including 9-beta-d-ribofuranosidoadenine, 5'-deoxy-5'-(methylthio)adenosine, and a triterpenoid.

    abstract：:Although Pleurotus abalonus is a well-known edible mushroom in Asia, there is a dearth of information on its antioxidant activity. The present report is the first one focused on the purification and characterization of 9-beta-d-ribofuranosidoadenine (ADO), 5'-deoxy-5'-(methylthio) adenosine (MTA) and a triterpenoid co...

    journal_title：Environmental toxicology and pharmacology

    pub_type： 杂志文章

    doi：10.1016/j.etap.2013.06.007

    authors： Zhang YN,Song M,Ng TB,Zhao L,Liu F

    更新日期：2013-09-01 00:00:00

  • Effects of topical exposure to a mixture of chlorpyrifos, cypermethrin and captan on the hematological and immunological systems in male Wistar rats.

    abstract：:Most Thai orchid farmers heavily used pesticide mixtures, and were shown to have various hematologic/immunologic alterations. The present study investigated the effect of exposure of male Wistar rats to a mixture of three pesticides (chlorpyrifos, cypermethrin and captan) that are most often used by the farmers. Three...

    journal_title：Environmental toxicology and pharmacology

    pub_type： 杂志文章

    doi：10.1016/j.etap.2018.02.010

    authors： Aroonvilairat S,Tangjarukij C,Sornprachum T,Chaisuriya P,Siwadune T,Ratanabanangkoon K

    更新日期：2018-04-01 00:00:00

  • Switch regulation of interleukin-1 beta in downstream of inflammatory cytokines induced by two micro-sized silica particles on differentiated THP-1 macrophages.

    abstract：:To investigate the regulated role of IL-1β in initiating and maintaining inflammation, PMA-differentiated THP-1 macrophages were exposed to two micro-sized crystalline silica particles (Si3-5μm and Si1μm) from 3h to 24h, respectively. Cytotoxicity and inflammatory cytokines (IL-1β, TNF-α and IL-6) expressions measured...

    journal_title：Environmental toxicology and pharmacology

    pub_type： 杂志文章

    doi：10.1016/j.etap.2014.12.017

    authors： Zhou T,Cui X,Zhou Y,Guo J,Rong Y,Chen W

    更新日期：2015-01-01 00:00:00