Daphnia intoxicated by nerve agent tabun can be treated using human antidotes.

abstract：:Endothelial nitric oxidase synthase (eNOS) uncoupling plays a causal role in endothelial dysfunction in atherosclerosis. Genistein consumption has been associated with the prevention of atherosclerosis. However, the effect of genistein on eNOS uncoupling has not been reported. A model of oxidized low-density lipoprote...

journal_title：Environmental toxicology and pharmacology

authors： Zhang HP,Zhao JH,Yu HX,Guo DX

更新日期：2016-03-01 00:00:00

abstract：:The aliphatic ether 1,6-dimethoxyhexane (DMH) was previously identified as a testicular toxicant. Testis protein extracts from control and DMH-treated rats were subjected to two-dimensional gel electrophoresis for comparison of protein expression profiles. MALDI-ToF peptide mass fingerprinting of differentially expres...

journal_title：Environmental toxicology and pharmacology

authors： Pelletier G,Masson S,Wang YL,Wade MG,Mohottalage S,Kumarathasan P,Vincent R,Poon R,Chu I

更新日期：2007-09-01 00:00:00

abstract：:In this study, the effects of acute and subacute formaldehyde (FA) exposures on spontaneous locomotor activity (SLMA), wet dog shake (WDS) behavior and pentylenetetrazole (PTZ) induced seizures were evaluated in Balb/C mice. SLMA was concentration dependently reduced after acute FA exposures at 1.8, 3.2, 4.5, 6.4, 9.7...

journal_title：Environmental toxicology and pharmacology

authors： Usanmaz SE,Akarsu ES,Vural N

更新日期：2002-03-01 00:00:00

abstract：:The present study was aimed to evaluate the effect of morin on blood glucose, insulin level, hepatic glucose regulating enzyme activities and glycogen level in experimental diabetes. Diabetes mellitus was induced by a single intraperitoneal injection of streptozotocin (STZ) (50 mg/kg b.w.). Five days after STZ injecti...

journal_title：Environmental toxicology and pharmacology

authors： Vanitha P,Uma C,Suganya N,Bhakkiyalakshmi E,Suriyanarayanan S,Gunasekaran P,Sivasubramanian S,Ramkumar KM

更新日期：2014-01-01 00:00:00

abstract：:Emamectin benzoate (EB) is an avermectin insecticide used extensively in pest control on vegetable and field crops. Few studies have been done for evaluating adverse effects of EB. In the current study, we evaluated the toxic effects of EB on male rats and the possible ameliorative role of fennel essential oil (FEO). ...

journal_title：Environmental toxicology and pharmacology

authors： El-Sheikh el-SA,Galal AA

更新日期：2015-05-01 00:00:00

abstract：:The present study was undertaken to scientifically evaluate, validate and compare the cardioprotective effects of lisinopril (Lsp), an angiotensin converting enzyme (ACE) inhibitor and vitamin E (Vit E), an antioxidant in the setting of ischemia and reperfusion (I-R) injury. An open chest left anterior descending coro...

journal_title：Environmental toxicology and pharmacology

authors： Mohanty IR,Arya DS,Dinda A,Gupta SK

更新日期：2013-03-01 00:00:00

abstract：:Triazine herbicide atrazine is considered to be moderately toxic to various aquatic animals. The aim of our study was to evaluate the acute embryotoxicity of atrazine and its two degradation products, desisopropylatrazine and desethylatrazine, and their mixture to the early life stages of zebrafish (Danio rerio) by me...

journal_title：Environmental toxicology and pharmacology

authors： Blahova J,Cocilovo C,Plhalova L,Svobodova Z,Faggio C

更新日期：2020-07-01 00:00:00

abstract：:Decabromodiphenyl ether (BDE209) is the major contaminant at e-waste recycling sites (EWRSs), and its potential toxicological effects on terrestrial organisms have received extensive attention. However, the impacts of BDE209 on the antioxidant defense system in terrestrial organisms remain vague. Therefore, indoor inc...

journal_title：Environmental toxicology and pharmacology

authors： Zhang W,Liu K,Chen L,Chen L,Lin K,Fu R

更新日期：2014-07-01 00:00:00

abstract：:Organophosphate flame retardants (OPFRs) are increasingly produced and used as alternatives of brominated flame-retardants (BFRs) and have become emerging marine environmental contaminants. So far, however, little is known regarding the biological effects of OPFRs in marine organisms. In this study, the biological eff...

journal_title：Environmental toxicology and pharmacology

authors： Wu H,Zhong M,Lu Z,Shan X,Li F,Ji C,Cong M

更新日期：2018-07-01 00:00:00

abstract：:The Opuntia ficus indica f. inermis methanolic flowers extract (OMFE) was phytochemical studied, in vitro tested for their potential antioxidant activity using 2,2-diphenyl-1-picrylhydrazyl (DPPH), reducing power, linoleic acid peroxidation assays and in vivo evaluated for its ability to prevent ethanol-induced gastri...

journal_title：Environmental toxicology and pharmacology

authors： Alimi H,Hfaiedh N,Bouoni Z,Sakly M,Ben Rhouma K

更新日期：2011-11-01 00:00:00

abstract：:The present study was aimed to analyze the effect of ZnO and TiO2 nanoparticles (NPs) on Haemato-immunological parameters in adult Tilapia, Oreochromis mossambicus. The nanoparticles size found as 47 nm and 30 nm for ZnO and TiO2 respectively. The acute toxicity (96 h) of ZnO (LC50: 100-110 ppm) and TiO2 (LC50: 80-90 ...

journal_title：Environmental toxicology and pharmacology

authors： Suganthi P,Murali M,Athif P,Sadiq Bukhari A,Syed Mohamed HE,Basu H,Singhal RK

更新日期：2019-02-01 00:00:00

abstract：:This study investigated the cytoprotective effect of baicalein (5,6,7-trihydroxyflavone) against oxidative stress-induced mitochondrial dysfunction. Electron spin resonance (ESR) spectrometry revealed that baicalein showed significant scavenging effects on superoxide radicals and hydroxyl radicals. When H(2)O(2) treat...

journal_title：Environmental toxicology and pharmacology

authors： Lee IK,Kang KA,Zhang R,Kim BJ,Kang SS,Hyun JW

更新日期：2011-01-01 00:00:00

abstract：:Since hypoxia-inducible factor-1α (HIF-1α) is the key transcription factor that enables cells to survive in hypoxia, we have investigated whether an upregulation of HIF-1α prevents the noise-induced hearing loss in BALB/c hybrid mice, which were intraperitoneally injected with CoCl(2) (a HIF-1α inducer) and exposed to...

journal_title：Environmental toxicology and pharmacology

authors： Chung JW,Shin JE,Han KW,Ahn JH,Kim YJ,Park JW,So HS

更新日期：2011-01-01 00:00:00

abstract：:The features of organophosphate-induced brain injuries were investigated. Rats were poisoned intraperitoneally with 9 mg/kg (1.8 LD(50)) of diisopropylfluorophosphate. Pyridostigmine bromide (0.1 mg/kg) and atropine methylnitrate (20 mg/kg), which are centrally inactive, were pre-treated intramuscularly to reduce the ...

journal_title：Environmental toxicology and pharmacology

authors： Kim YB,Hur GH,Shin S,Sok DE,Kang JK,Lee YS

更新日期：1999-04-01 00:00:00

abstract：:In assessing interindividual variability in metabolic activation, the toxic metabolite is often too unstable for conventional analysis. Possible alternatives include a stable product of the reactive metabolite e.g. cysteinyl derivatives of N-acetyl-4-benzoquinoneimine, the toxic metabolite of paracetamol, adducts with...

journal_title：Environmental toxicology and pharmacology

authors： Boobis AR

更新日期：1996-10-15 00:00:00

abstract：:In this study, we report the antioxidant and antitoxic potential of chemically synthesized 4-oxo-2-phenyl-4H-chromene-7,8-diyl bis((1-amino-2-hydroxypropyl)carbamate) (DHF-BAHPC) compound using in vitro and in vivo assays. The DHF-BAHPC was synthesized by linking 7,8-Dihydroxyflavone (DHF) with two molecules of Fmoc-t...

journal_title：Environmental toxicology and pharmacology

authors： Mohankumar T,Lalithamba HS,Manigandan K,Muthaiyan A,Elangovan N

更新日期：2020-10-01 00:00:00

abstract：:The mutagenic and genotoxic effect of 'Rasayanzine', an atrazine herbicide, was carried out in fish Channa punctatus using micronucleus and single cell gel electrophoresis (SCGE) assays. Three sub-lethal concentrations of the test material viz., SL-I (1/5th LC(50)=∼8.48 mgL(-1)), SL-II (1/8th LC(50)=∼5.30 mgL(-1)) and...

journal_title：Environmental toxicology and pharmacology

authors： Nwani CD,Nagpure NS,Kumar R,Kushwaha B,Kumar P,Lakra WS

更新日期：2011-03-01 00:00:00

abstract：:It is well known that developmental exposure to polychlorinated biphenyls (PCBs) could cause learning and memory deficits, but the underlying mechanisms are not clear. Actin cytoskeleton is directly involved in synaptic plasticity which is considered critical to learning and memory formation by LIM kinase 1 (LIMK-1)/c...

journal_title：Environmental toxicology and pharmacology

authors： Tang F,Yan C,Wu S,Li F,Yu Y,Gao Y,Jin X,Shen X

更新日期：2007-03-01 00:00:00

abstract：:Effects of aluminum (Al) on membrane properties of excitable cells are not fully understood. Several reports have identified cellular membranes as sensitive targets for Al intoxication. In the present study, we tested the hypothesis that treatment with Al would alter membrane fluidity and potential and these changes w...

journal_title：Environmental toxicology and pharmacology

authors： Johnson VJ,Tsunoda M,Murray TF,Sharma RP

更新日期：2005-02-01 00:00:00

abstract：:Fucoidan is a complex sulfated polysaccharide, derived from marine brown seaweed. In the present study, we investigated the effects of fucoidan on improving learning and memory impairment in rats induced by infusion of Aβ (1-40), and its possible mechanisms. The results indicated that fucoidan could ameliorate Aβ-indu...

journal_title：Environmental toxicology and pharmacology

authors： Gao Y,Li C,Yin J,Shen J,Wang H,Wu Y,Jin H

更新日期：2012-03-01 00:00:00

abstract：:Epidemiological studies indicate that arsenic exposure induces hypertension. We hypothesized that arsenate exposure modulates the contractility of vascular smooth muscle through the stress response. Intraperitoneal injection of sodium arsenate (15mg/kg) 16h before increased not only the blood pressure of rats but also...

journal_title：Environmental toxicology and pharmacology

authors： Park TG,Seong Y,Suk K,Ha JH,Kim I

更新日期：2005-02-01 00:00:00

abstract：:Deoxynivalenol (DON) has broad toxicity in animals and humans. In this study the impact of DON treatment on apoptotic pathways in PC12 cells was determined. The effects of DON were evaluated on (i) typical indicators of apoptosis, including cellular morphology, cell activity, lactate dehydrogenase (LDH) release, and a...

journal_title：Environmental toxicology and pharmacology

authors： Wang X,Xu W,Fan M,Meng T,Chen X,Jiang Y,Zhu D,Hu W,Gong J,Feng S,Wu J,Li Y

更新日期：2016-04-01 00:00:00

abstract：:Phthalates are chemicals widely used in industry and the consequences for human health caused by exposure to these agents are of significant current interest. Phthalate toxicity targets the reproductive and respiratory systems primarily, but they also may be involved in the processes of carcinogenesis and even in auti...

journal_title：Environmental toxicology and pharmacology

authors： Ventrice P,Ventrice D,Russo E,De Sarro G

更新日期：2013-07-01 00:00:00

abstract：:The toxicity of chlorobenzenes to Tetrahymena growth metabolism was studied by microcalorimetry. The growth constant (k), peak time (T) and generation times (T(G)) were calculated. IC(50) of chlorobenzenes was obtained through the kinetic parameters. The results suggested that the order of toxicity was 1,2,4-trichloro...

journal_title：Environmental toxicology and pharmacology

authors： Zhang T,Li X,Min X,Fang T,Zhang Z,Yang L,Liu P

更新日期：2012-05-01 00:00:00

abstract：:Impact of smoking on the levels of apolipoprotein B (APOB) was evaluated by analyzing data from National Health and Nutrition Examination Survey for the years 2007-2012 for US adolescents aged 12-19 years and adults aged >=20 years. When adjustments were made for the effects of age, gender, race/ethnicity, body mass i...

journal_title：Environmental toxicology and pharmacology

authors： Jain RB

更新日期：2017-07-01 00:00:00

abstract：:The wide range of potential health beneficial effects of isoflavones, including a chemoprentive action, have prompted us to study the potential benefits of genistein and daidzein in an experimental model of environmental pollution impact on lung tissue. A diesel engine placed was used to generate reproducible emission...

journal_title：Environmental toxicology and pharmacology

authors： Morin JP,Rumigny JF,Bion A,Dionnet F

更新日期：2002-11-01 00:00:00

abstract：:The novel niosomal system aimed to deliver the active drug entity to the target site. The objective of this study was to prepare and evaluate the effect of itraconazole niosome on the in vitro susceptibility of Leishmania tropica as compared to itraconazole alone or tartar emetic. The overall growth rate of promastigo...

journal_title：Environmental toxicology and pharmacology

authors： Khazaeli P,Sharifi I,Talebian E,Heravi G,Moazeni E,Mostafavi M

更新日期：2014-07-01 00:00:00

abstract：:Glyphosate is the active ingredient and polyoxyethyleneamine, the major component, is the surfactant present in the herbicide Roundup formulation. The objective of this study was to analyze potential cytotoxicity of the Roundup and its fundamental substance (glyphosate). Albino male rats were intraperitoneally treated...

journal_title：Environmental toxicology and pharmacology

authors： El-Shenawy NS

更新日期：2009-11-01 00:00:00

abstract：:There is controversy as to whether low-level chronic exposure to methylmercury (MeHg) through maternal fish consumption may cause subtle effects in the developing child, owing in part to the potential ameliorating effects of beneficial seafood nutrients. The aim of the present investigation was to assess the ameliorat...

journal_title：Environmental toxicology and pharmacology

authors： Folven KI,Glover CN,Malde MK,Lundebye AK

更新日期：2009-07-01 00:00:00

abstract：:Crops produced through genetic modification are beginning to reach the market and many genetically-modified crops are under development. Since genetic modification results in the introduction of new proteins into the food plant the safety of the newly introduced proteins must be assessed. The potential allergenicity o...

journal_title：Environmental toxicology and pharmacology

authors： Taylor SL

更新日期：1997-11-01 00:00:00