Expression of fibronectin and type I collagen by human dental pulp cells and gingiva fibroblasts grown on fibronectin substrate.

Abstract:

:Specific antibodies and indirect immunoperoxidase labelling were used to study the intracellular production of collagen and fibronectin by cells grown on fibronectin-coated glass; the same cell populations seeded on uncoated glass were used as controls. Strong intracellular staining for type I collagen was seen in all cases, but immunostaining for fibronectin was very faint or negative in both gingival and pulp cells grown on the fibronectin substrate, in contrast to control cells. Thus, fibronectin substrate inhibited fibronectin synthesis by the cultured cells, but did not seem to influence type I collagen synthesis.

journal_name

Arch Oral Biol

journal_title

Archives of oral biology

authors

Veron MH,Couble ML,Caillot G,Hartmann DJ,Magloire H

doi

10.1016/0003-9969(90)90089-s

subject

Has Abstract

pub_date

1990-01-01 00:00:00

pages

565-9

issue

7

eissn

0003-9969

issn

1879-1506

pii

0003-9969(90)90089-S

journal_volume

35

pub_type

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